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Journal Ann Intern Med

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Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians.

Amir Qaseem, Itziar Etxeandia-Ikobaltzeta, Jennifer S Lin, Nick Fitterman, Tatyana Shamliyan, Timothy J Wilt, ,

<h4>Description</h4>The American College of Physicians (ACP) developed this guideline to provide clinical recommendations on the role of colonoscopy for diagnostic evaluation of colorectal cancer (CRC) after a presumed diagnosis of acute left-sided colonic diverticulitis and on the role of pharmacologic, nonpharmacologic, and elective surgical interventions to prevent recurrence after initial ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2022, :]

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Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians.

Amir Qaseem, Itziar Etxeandia-Ikobaltzeta, Jennifer S Lin, Nick Fitterman, Tatyana Shamliyan, Timothy J Wilt, ,

<h4>Description</h4>The American College of Physicians (ACP) developed this guideline to provide clinical recommendations on the diagnosis and management of acute left-sided colonic diverticulitis in adults. This guideline is based on current best available evidence about benefits and harms, taken in the context of costs and patient values and preferences.<h4>Methods</h4>The ACP ... Read more >>

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Annals Graphic Medicine - Nurse Reviewing the Chart of a Critically Ill Patient With COVID-19.

Arun Thekkekarott Kuruvila, Nikita Hegde,

Ann Intern Med (Annals of internal medicine)
[2022, :]

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The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia.

Theodore E Warkentin, Menaka Pai,

Ann Intern Med (Annals of internal medicine)
[2022, :]

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Annals Video Summary - Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis: A Systematic Review.

Ann Intern Med (Annals of internal medicine)
[2022, :]

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Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis : A Systematic Review.

Ethan M Balk, Gaelen P Adam, Monika Reddy Bhuma, Kristin J Konnyu, Ian J Saldanha, Michael D Beland, Nishit Shah,

<h4>Background</h4>Clinicians need to better understand the value of computed tomography (CT) imaging and nonsurgical treatment options to manage acute left-sided colonic diverticulitis.<h4>Purpose</h4>To evaluate CT imaging, outpatient treatment of uncomplicated diverticulitis, antibiotic treatment, and interventional radiology for patients with complicated diverticulitis.<h4>Data sources</h4>MEDLINE, Cochrane Central Register of Controlled Trials, Cochrane Database of ... Read more >>

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Case Series of Thrombosis With Thrombocytopenia Syndrome After COVID-19 Vaccination-United States, December 2020 to August 2021.

Isaac See, Allison Lale, Paige Marquez, Michael B Streiff, Allison P Wheeler, Naomi K Tepper, Emily Jane Woo, Karen R Broder, Kathryn M Edwards, Ruth Gallego, Andrew I Geller, Kelly A Jackson, Shashi Sharma, Kawsar R Talaat, Emmanuel B Walter, Imo J Akpan, Thomas L Ortel, Victor C Urrutia, Shannon C Walker, Jennifer C Yui, Tom T Shimabukuro, Adamma Mba-Jonas, John R Su, David K Shay,

<h4>Background</h4>Thrombosis with thrombocytopenia syndrome (TTS) is a potentially life-threatening condition associated with adenoviral-vectored COVID-19 vaccination. It presents similarly to spontaneous heparin-induced thrombocytopenia. Twelve cases of cerebral venous sinus thrombosis after vaccination with the Ad26.COV2.S COVID-19 vaccine (Janssen/Johnson & Johnson) have previously been described.<h4>Objective</h4>To describe surveillance data and reporting rates of ... Read more >>

Ann Intern Med (Annals of internal medicine)
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Evaluation and Management After Acute Left-Sided Colonic Diverticulitis : A Systematic Review.

Ethan M Balk, Gaelen P Adam, Wangnan Cao, Shivani Mehta, Nishit Shah,

<h4>Background</h4>The value of interventions used after acute colonic diverticulitis is unclear.<h4>Purpose</h4>To evaluate postdiverticulitis colonoscopy and interventions to prevent recurrent diverticulitis.<h4>Data sources</h4>MEDLINE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Embase, CINAHL, and ClinicalTrials.gov from 1 January 1990 through 16 November 2020.<h4>Study selection</h4>Comparative studies of interventions of interest ... Read more >>

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Antibody Response to a Fourth Messenger RNA COVID-19 Vaccine Dose in Kidney Transplant Recipients: A Case Series.

Sophie Caillard, Olivier Thaunat, Ilies Benotmane, Christophe Masset, Gilles Blancho,

Ann Intern Med (Annals of internal medicine)
[2022, :]

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Web Exclusive. Annals Graphic Medicine - The Endless Battle.

Emily S Yin,

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):W12-W13]

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Prediction of End-Stage Kidney Disease Using Estimated Glomerular Filtration Rate With and Without Race : A Prospective Cohort Study.

Joshua D Bundy, Katherine T Mills, Amanda H Anderson, Wei Yang, Jing Chen, Jiang He, ,

<h4>Background</h4>New estimated glomerular filtration rate (eGFR) equations removed race adjustment, but the impact of its removal on prediction of end-stage kidney disease (ESKD) is unknown.<h4>Objective</h4>To compare the ESKD prediction performance of different eGFR equations.<h4>Design</h4>Observational, prospective cohort study.<h4>Setting</h4>7 U.S. clinical centers.<h4>Participants</h4>3873 participants with chronic kidney disease (CKD) from the CRIC (Chronic ... Read more >>

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Eliminating Racial Inequities in Kidney Health: Much More Than Revising Estimating Equations.

Akinlolu Ojo,

Ann Intern Med (Annals of internal medicine)
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Summary for Patients: Fracture Risk During Osteoporosis Drug Holidays.

Ann Intern Med (Annals of internal medicine)
[2022, :]

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Comparative Fracture Risk During Osteoporosis Drug Holidays After Long-Term Risedronate Versus Alendronate Therapy : A Propensity Score-Matched Cohort Study.

Kaleen N Hayes, Kevin A Brown, Angela M Cheung, Sandra A Kim, David N Juurlink, Suzanne M Cadarette,

<h4>Background</h4>An osteoporosis drug holiday is recommended for most patients after 3 to 5 years of therapy. Risedronate has a shorter half-life than alendronate, and thus the residual length of fracture protection may be shorter.<h4>Objective</h4>To examine the comparative risks of drug holidays after long-term (≥3 years) risedronate versus alendronate therapy.<h4>Design</h4>Population-based, matched, ... Read more >>

Ann Intern Med (Annals of internal medicine)
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Opioid Use Disorder.

Jessica L Taylor, Jeffrey H Samet,

Opioid use disorder (OUD) is a treatable chronic disorder with episodes of remission and recurrence characterized by loss of control of opioid use, compulsive use, and continued use despite harms. If untreated, OUD is associated with significant morbidity and mortality. Buprenorphine and methadone reduce fatal and nonfatal opioid overdose and ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):ITC1-ITC16]

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Residual Confounding in Health Plan Performance Assessments: Evidence From Randomization in Medicaid.

Jacob Wallace, J Michael McWilliams, Anthony Lollo, Janet Eaton, Chima D Ndumele,

<h4>Background</h4>Risk adjustment is used widely in payment systems and performance assessments, but the extent to which it distinguishes plan or provider effects from confounding due to patient differences is typically unknown.<h4>Objective</h4>To assess the degree to which risk-adjusted measures of health plan performance adequately adjust for the variation across plans that ... Read more >>

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Cardiometabolic Disease Burden and Steroid Excretion in Benign Adrenal Tumors : A Cross-Sectional Multicenter Study.

Alessandro Prete, Anuradhaa Subramanian, Irina Bancos, Vasileios Chortis, Stylianos Tsagarakis, Katharina Lang, Magdalena Macech, Danae A Delivanis, Ivana D Pupovac, Giuseppe Reimondo, Ljiljana V Marina, Timo Deutschbein, Maria Balomenaki, Michael W O'Reilly, Lorna C Gilligan, Carl Jenkinson, Tomasz Bednarczuk, Catherine D Zhang, Tina Dusek, Aristidis Diamantopoulos, Miriam Asia, Agnieszka Kondracka, Dingfeng Li, Jimmy R Masjkur, Marcus Quinkler, Grethe Å Ueland, M Conall Dennedy, Felix Beuschlein, Antoine Tabarin, Martin Fassnacht, Miomira Ivović, Massimo Terzolo, Darko Kastelan, William F Young, Konstantinos N Manolopoulos, Urszula Ambroziak, Dimitra A Vassiliadi, Angela E Taylor, Alice J Sitch, Krishnarajah Nirantharakumar, Wiebke Arlt, ,

<h4>Background</h4>Benign adrenal tumors are commonly discovered on cross-sectional imaging. Mild autonomous cortisol secretion (MACS) is regularly diagnosed, but its effect on cardiometabolic disease in affected persons is ill defined.<h4>Objective</h4>To determine cardiometabolic disease burden and steroid excretion in persons with benign adrenal tumors with and without MACS.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>14 endocrine secondary and ... Read more >>

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Knowledge Gaps, Challenges, and Opportunities in Health and Prevention Research for Asian Americans, Native Hawaiians, and Pacific Islanders: A Report From the 2021 National Institutes of Health Workshop.

Alka M Kanaya, Ann W Hsing, Sela V Panapasa, Namratha R Kandula, Maria Rosario G Araneta, Daichi Shimbo, Paul Wang, Scarlett L Gomez, Jinkook Lee, K M Venkat Narayan, Marjorie K L Mala Mau, Sonali Bose, Martha L Daviglus, Frank B Hu, Nadia Islam, Chandra L Jackson, Merle Kataoka-Yahiro, John S K Kauwe, Simin Liu, Grace X Ma, Tung Nguyen, Latha Palaniappan, V Wendy Setiawan, Chau Trinh-Shevrin, Janice Y Tsoh, Dhananjay Vaidya, Barbara Vickrey, Thomas J Wang, Nathan D Wong, Sean Coady, Yuling Hong,

Asian Americans (AsA), Native Hawaiians, and Pacific Islanders (NHPI) comprise 7.7% of the U.S. population, and AsA have had the fastest growth rate since 2010. Yet the National Institutes of Health (NIH) has invested only 0.17% of its budget on AsA and NHPI research between 1992 and 2018. More than ... Read more >>

Ann Intern Med (Annals of internal medicine)
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The Imperfect Science of Evaluating Performance: How Bad and Who Cares?

Aaron L Schwartz, Rachel M Werner,

Ann Intern Med (Annals of internal medicine)
[2022, :]

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Cardiometabolic Morbidity of Mild Cortisol Excess.

André Lacroix,

Ann Intern Med (Annals of internal medicine)
[2022, :]

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In persons at intermediate risk for CVD, polypills reduce a composite of CV events at 5 y.

Krysta Brown, Anthony A Donato,

<h4>Source citation</h4>Joseph P, Roshandel G, Gao P, et al. <b>Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis.</b> Lancet. 2021;398:1133-46. 34469765. ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):JC2]

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In older patients at high risk for stroke, intensive AF screening with an implantable loop recorder did not reduce stroke.

Mohammed Yousufuddin, Arshad Jahangir,

<h4>Source citation</h4>Svendsen JH, Diederichsen SZ, Højberg S, et al. <b>Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial.</b> Lancet. 2021;398:1507-16. 34469766. ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):JC8]

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In uninfected household contacts of patients with COVID-19, REGEN-COV reduced symptomatic COVID-19 at 28 d.

Darren Lau, Lynora Saxinger,

<h4>Source citation</h4>O'Brien MP, Forleo-Neto E, Musser BJ, et al. <b>Subcutaneous REGEN-COV antibody combination to prevent Covid-19.</b> N Engl J Med. 2021;385:1184-95. 34347950. ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):JC5]

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In long-term, higher-dose opioid use, dose tapering was linked to overdose and mental health crises.

Peter MacDougall,

<h4>Source citation</h4>Agnoli A, Xing G, Tancredi DJ, et al. <b>Association of dose tapering with overdose or mental health crisis among patients prescribed long-term opioids.</b> JAMA. 2021;326:411-9. 34342618. ... Read more >>

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):JC11]

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Annals On Call - Bleeding Risk During Extended Anticoagulation for Unprovoked VTE.

Robert M Centor, Jori E May,

Ann Intern Med (Annals of internal medicine)
[2022, 175(1):OC1]

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