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Journal Anesthesiology

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Association of Surgical Hospitalization with Brain Amyloid Deposition: The Atherosclerosis Risk in Communities-Positron Emission Tomography (ARIC-PET) Study.

Keenan A Walker, Rebecca F Gottesman, Josef Coresh, A Richey Sharrett, David S Knopman, Thomas H Mosley, Alvaro Alonso, Yun Zhou, Dean F Wong, Charles H Brown,

BACKGROUND:As more older adults undergo surgery, it is critical to understand the long-term effects of surgery on brain health, particularly in relation to the development of Alzheimer's disease. This study examined the association of surgical hospitalization with subsequent brain β-amyloid deposition in nondemented older adults. METHODS:The Atherosclerosis Risk in Communities-Positron ... Read more >>

Anesthesiology (Anesthesiology)
[2020, 132(6):1407-1418]

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Local Sympathectomy Promotes Anti-inflammatory Responses and Relief of Paclitaxel-induced Mechanical and Cold Allodynia in Mice.

Raquel Tonello, Wenrui Xie, Sang Hoon Lee, Min Wang, Xiaojuan Liu, Judith A Strong, Jun-Ming Zhang, Temugin Berta,

BACKGROUND:Patients undergoing cancer treatment often experience chemotherapy-induced neuropathic pain at their extremities, for which there is no U.S. Food and Drug Administration-approved drug. The authors hypothesized that local sympathetic blockade, which is used in the clinic to treat various pain conditions, can also be effective to treat chemotherapy-induced neuropathic pain. ... Read more >>

Anesthesiology (Anesthesiology)
[2020, 132(6):1540-1553]

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Intubation and Ventilation amid the COVID-19 Outbreak: Wuhan's Experience.

Lingzhong Meng, Haibo Qiu, Li Wan, Yuhang Ai, Zhanggang Xue, Qulian Guo, Ranjit Deshpande, Lina Zhang, Jie Meng, Chuanyao Tong, Hong Liu, Lize Xiong,

The COVID-19 outbreak has led to 80,409 diagnosed cases and 3,012 deaths in mainland China based on the data released on March 4, 2020. Approximately 3.2% of patients with COVID-19 required intubation and invasive ventilation at some point in the disease course. Providing best practices regarding intubation and ventilation for ... Read more >>

Anesthesiology (Anesthesiology)
[2020, 132(6):1317-1332]

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Byline Backstory No. 5: Physic(k)al Pursuits at Ursinus with Mauchly's Skateboard, Snyder's Unicycle…and Einstein's Bike?

Anesthesiology (Anesthesiology)
[2020, 132(6):1568]

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Sevoflurane Enhances Proliferation, Metastatic Potential of Cervical Cancer Cells via the Histone Deacetylase 6 Modulation In Vitro.

Wenwen Zhang, Bo Sheng, Sisi Chen, Hailin Zhao, Lingzhi Wu, Yibing Sun, Jiang Cui, Xueqiong Zhu, Daqing Ma,

BACKGROUND:Sevoflurane is commonly used for cervical cancer surgery, but its effect on cervical cancer cell biology remains unclear. This mechanistic study explores how sevoflurane affects the proliferation and metastatic potential of immortalized cervical cancer cell lines. METHODS:Cultured cervical cancer Caski and HeLa lines were exposed to 1, 2, or 3% ... Read more >>

Anesthesiology (Anesthesiology)
[2020, 132(6):1469-1481]

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Benjamin Harrison Awakens a Navy Anesthetized by America's Apathy and Complacency.

Anesthesiology (Anesthesiology)
[2020, 132(6):1370]

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Shadowing the Abbess: Wood Library-Museum Exhibit Designer John Byrne and His "Superior" Spouse.

Anesthesiology (Anesthesiology)
[2020, 132(6):1418]

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Alypin: An Antithetical Anesthetic.

Anesthesiology (Anesthesiology)
[2020, 132(6):1527]

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This Month in Anesthesiology.

Anesthesiology (Anesthesiology)
[2020, 132(6):A1-A2]

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Uncertainty and Certainty.

Evan D Kharasch,

Anesthesiology (Anesthesiology)
[2020, :]

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Prophylactic Intrathecal Morphine and Prevention of Post-Dural Puncture Headache: A Randomized Double-blind Trial: Erratum.

Anesthesiology (Anesthesiology)
[2020, :]

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Anesthesia as Decoupling?

Andrew E Hudson,

Anesthesiology (Anesthesiology)
[2020, :]

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Population Volume Kinetics in Volunteers: Reply: Retraction.

Anesthesiology (Anesthesiology)
[2020, :]

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Population Volume Kinetics in Volunteers: Comment: Retraction.

Anesthesiology (Anesthesiology)
[2020, :]

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Goal-directed versus Standard Fluid Therapy to Decrease Ileus after Open Radical Cystectomy: A Prospective Randomized Controlled Trial.

Vittoria Arslan-Carlon, Kay See Tan, Guido Dalbagni, Alessia C Pedoto, Harry W Herr, Bernard H Bochner, Eugene K Cha, Timothy F Donahue, Mary Fischer, S Machele Donat,

BACKGROUND:Postoperative ileus is a common complication of intraabdominal surgeries, including radical cystectomy with reported rates as high as 32%. Perioperative fluid administration has been associated with improvement in postoperative ileus rates, but it is difficult to generalize because earlier studies lacked standardized definitions of postoperative ileus and other relevant outcomes. ... Read more >>

Anesthesiology (Anesthesiology)
[2020, :]

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Shared Ventilation: Toward Safer Ventilator Splitting in Resource Emergencies.

Anne D Cherry, Jhaymie Cappiello, Muath Bishawi, Melanie G Hollidge, David B MacLeod,

Anesthesiology (Anesthesiology)
[2020, :]

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Autopilots in the Operating Room: Safe Use of Automated Medical Technology.

Keith J Ruskin, Chase Corvin, Stephen C Rice, Scott R Winter,

Automated medical technology is becoming an integral part of routine anesthetic practice. Automated technologies can improve patient safety, but may create new workflows with potentially surprising adverse consequences and cognitive errors that must be addressed before these technologies are adopted into clinical practice. Industries such as aviation and nuclear power ... Read more >>

Anesthesiology (Anesthesiology)
[2020, :]

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Wearing an N95 Respiratory Mask: An Unintended Exercise Benefit?

Bryan A Davis, Lawrence C Tsen,

Anesthesiology (Anesthesiology)
[2020, :]

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Isoflurane Exposure in Juvenile Caenorhabditis elegans Causes Persistent Changes in Neuron Dynamics.

Gregory S Wirak, Christopher V Gabel, Christopher W Connor,

BACKGROUND:Animal studies demonstrate that anesthetic exposure during neurodevelopment can lead to persistent behavioral impairment. The changes in neuronal function underlying these effects are incompletely understood. Caenorhabditis elegans is well suited for functional imaging of postanesthetic effects on neuronal activity. This study aimed to examine such effects within the neurocircuitry underlying ... Read more >>

Anesthesiology (Anesthesiology)
[2020, :]

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Perioperative Neurocognitive Disorder: Comment.

Giovanni Giordano, Francesco Pugliese, Federico Bilotta,

Anesthesiology (Anesthesiology)
[2020, :]

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Considerations for Assessing Risk of Provider Exposure to SARS-CoV-2 after a Negative Test.

Dustin R Long, Jacob E Sunshine, Wil Van Cleve,

Anesthesiology (Anesthesiology)
[2020, :]

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Enhanced Recovery after Lumbar Spine Fusion: A Randomized Controlled Trial to Assess the Quality of Patient Recovery.

Ellen M Soffin, James D Beckman, Audrey Tseng, Haoyan Zhong, Russel C Huang, Michael Urban, Carrie R Guheen, Han-Jo Kim, Frank P Cammisa, Jemiel A Nejim, Frank J Schwab, Isabel F Armendi, Stavros G Memtsoudis,

BACKGROUND:Prospective trials of enhanced recovery after spine surgery are lacking. We tested the hypothesis that an enhanced recovery pathway improves quality of recovery after one- to two-level lumbar fusion. METHODS:A patient- and assessor-blinded trial of 56 patients randomized to enhanced recovery (17 evidence-based pre-, intra-, and postoperative care elements) or ... Read more >>

Anesthesiology (Anesthesiology)
[2020, :]

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Intraoperative Circuit Leak Likely Caused by Surgical Prep.

Yuki Kojima, Kazuya Hirabayashi, Tatsuhiro Oka,

Anesthesiology (Anesthesiology)
[2020, :]

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Perioperative Neurocognitive Disorder: Reply.

Roderic G Eckenhoff, Maryellen F Eckenhoff,

Anesthesiology (Anesthesiology)
[2020, :]

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An Online Educational Platform in the COVID-19 Pandemic.

Lucy Liu Yang, Jia Liu Stevens, Marta Janina Campbell,

Anesthesiology (Anesthesiology)
[2020, :]

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