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Snakebites in Suriname: Evaluation of the Protocolled Administration of Anti-Snake Venom in a Tertiary Care Setting.

Navin Ramdhani, Simone Jonker, Kevin van 't Kruys, Rakesh Bansie, Wilco Zijlmans,

Venomous snakebites regularly occur in Suriname, a middle-income country located on the north coast of South America. Officially reported data on incidence and mortality are lacking. The aim of this retrospective study was to assess whether the use of our national snakebite protocol with selective administration of anti-snake venom (ASV) ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Control of Rabies as a Victim of Its Own Success: Perception of Risk within a Latin American Population.

Felipe Rocha,

Control of Rabies as a Victim of Its Own Success: Perception of Risk within a Latin American Population. ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Test, Treat, Track, Test, and Treat Active Surveillance toward Elimination of Schistosomiasis: A Feasibility Study.

Reda M R Ramzy, Amal Rabiee, Khaled M Abd Elaziz, Carl H Campbell, Nupur Kittur, Daniel G Colley, Ayat A Haggag,

We assessed the feasibility of using a test, treat, track, test, and treat (5T) active surveillance strategy to identify and treat individuals with schistosomiasis in three very low-prevalence villages in Kafr El Sheikh Governorate, Egypt. Primary index cases (PICs) were identified using the point-of-care circulating cathodic antigen (POC-CCA) assay in ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Spatial Inequality Hides the Burden of Dog Bites and the Risk of Dog-Mediated Human Rabies.

Micaela De la Puente-León, Michael Z Levy, Amparo M Toledo, Sergio Recuenco, Julianna Shinnick, Ricardo Castillo-Neyra,

Since its reintroduction in 2015, rabies has been established as an enzootic disease among the dog population of Arequipa, Peru. Given the unknown rate of dog bites, the risk of human rabies transmission is concerning. Our objective was to estimate the rate of dog bites in the city and to ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Case Report: Novel Coronavirus-A Potential Cause of Acute Pancreatitis?

Syed Muhammad Mashhood Ali Bokhari, Fatima Mahmood,

A 32-year-old medical practitioner presented to the emergency department with complaints of severe abdominal pain, fever, and vomiting, 1 week after the diagnosis of COVID-19. The patient did not report any comorbid conditions, alcohol usage, or gallstone disease. Laboratory and radiological investigations revealed the diagnosis of acute pancreatitis. He underwent ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Case Report: COVID-19-Related Pneumothorax-Case Series Highlighting a Significant Complication.

Shaikha D Al-Shokri, Ashraf O E Ahmed, Ahmed Osman Saleh, Mohamed AbouKamar, Khalid Ahmed, Mouhand F H Mohamed,

COVID-19 is a recent outbreak in China and rapidly spread worldwide. Lung consolidation is the most common radiologic finding of COVID-19 pneumonia. Pneumothorax has been rarely reported as a complication of severe COVID-19 pneumonia. Early recognition and management are detrimental to the outcome. We here report three cases of SARS-CoV-2 ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Attitudes, Anxiety, and Behavioral Practices Regarding COVID-19 among University Students in Jordan: A Cross-Sectional Study.

Amin N Olaimat, Iman Aolymat, Nour Elsahoryi, Hafiz M Shahbaz, Richard A Holley,

The COVID-19 pandemic represents a major public health, economic, political, and scientific concern in most countries around the globe where COVID-19 cases and deaths have been confirmed. This study assessed the attitudes, anxiety, and behavioral practices of university students in Jordan regarding COVID-19 during the early period of the infection ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Early Postnatal and Preschool-Age Infection by Fasciola spp.: Report of Five Cases from Vietnam and Worldwide Review.

Nguyen Van De, Thanh Hoa Le, Veronica H Agramunt, Santiago Mas-Coma,

Fascioliasis is reported in five Vietnamese children aged 4 years or younger. A 10-month-old girl child and a 12-month-old boy child are the youngest patients ever diagnosed. Eggs in stools suggested an infection occurred at 5-6 months and 7-8 months of age, respectively. DNA sequencing and egg size indicated this ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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An Atypical Case of Autochthonous Cutaneous Leishmaniasis Associated with Naturally Infected Phlebotomine Sand Flies in Texas, United States.

Evan J Kipp, Marcos de Almeida, Paula L Marcet, Richard S Bradbury, Theresa Benedict, Wuling Lin, Ellen M Dotson, Melinda Hergert,

In the United States, phlebotomine sand flies carrying Leishmania (Leishmania) mexicana are endemic along the southern border. However, relatively little is known about the enzootic and zoonotic transmission of L. (L.) mexicana within the United States, and autochthonous cases of the consequent disease are rarely reported. We investigated an atypical ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Bulla Formation and Tension Pneumothorax in a Patient with COVID-19.

Kosuke Yasukawa, Arathy Vamadevan, Rosemarie Rollins,

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Evidence of Microbiome-Drug Interactions between the Antimalarial Lumefantrine and Gut Microbiota in Mice.

Matthew M Ippolito, Joshua E Denny, Elizabeth Nenortas, Theresa A Shapiro, Nathan W Schmidt,

The antimalarial drug lumefantrine (LF) exhibits erratic pharmacokinetics (PK). Intersubject variability might be attributed, in part, to differences in the gut microbiome-mediated drug metabolism. We assessed LF disposition in healthy mice stratified by enterotype to explore associations between the gut microbiota and LF PK. Gut microbiota enterotypes were classified according ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Seroprevalence of Measles, Rubella, Tetanus, and Diphtheria Antibodies among Children in Haiti, 2017.

Anna A Minta, Jocelyne Andre-Alboth, Lana Childs, Doug Nace, Gloria Rey-Benito, Jacques Boncy, Paul Adrien, Jeannot François, Nadia Phaïmyr Jn Charles, Valery Blot, Jodi Vanden Eng, Jeffrey W Priest, Eric Rogier, Rania A Tohme,

In Haiti, measles, rubella, and maternal and neonatal tetanus have been eliminated, but a diphtheria outbreak is ongoing as of 2019. We conducted a national representative, household-based, two-stage cluster survey among children aged 5-7 years in 2017 to assess progress toward maintenance of control and elimination of selected vaccine-preventable diseases ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Clinical and Laboratory Profile of Fatal Dengue Cases at a Tertiary Care Private Hospital in Mumbai, India.

Tanu Singhal, Vatsal Kothari,

Dengue-related mortality has significantly reduced with early and appropriate fluid resuscitation. However, we continue to see dengue-related fatalities in patients despite early intervention and advanced critical care support. This was a retrospective study conducted at a tertiary care private hospital in Mumbai, India. All patients dying of dengue in the ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Temporal Change of SARS-CoV-2 in Clinical Specimens of COVID-19 Pneumonia Patients.

Viravarn Luvira, Akanitt Jittmittraphap, Sant Muangnoicharoen, Nantarat Chantawat, Weena Janwitthayanan, Pornsawan Leaungwutiwong,

The quality and type of specimen collection affect the sensitivity of real-time reverse transcriptase-PCR (rRT-PCR) for the diagnosis of SARS-CoV-2. In this report, the course over time of rRT-PCR for SARS-CoV-2 in 26 clinical specimens collected from the upper (nasopharyngeal and throat swabs) and lower (sputum) respiratory tracts of COVID-19 ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Case Report: Dynamics of Acquired Fluoroquinolone Resistance under Standardized Short-Course Treatment of Multidrug-Resistant Tuberculosis.

Jean Claude Semuto Ngabonziza, Armand Van Deun, Patrick Migambi, Niyigena Esdras Belamo, Dusabe Théogène, Yves Mucyo Habimana, Bertin Ushizimpumu, Wim Mulders, Tom Decroo, Dissou Affolabi, Philip Supply, Bouke C de Jong, Leen Rigouts,

We report a case of acquired fluoroquinolone (FQ) resistance under short-course multidrug-resistant tuberculosis (MDR-TB) treatment. The patient was managed at Kabutare hospital, one of the two specialized MDR-TB clinics in Rwanda. A low dose of moxifloxacin was used in the first three critical months. Acquired resistance was identified at the ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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The Role of Mass Drug Administration of Antimalarials.

Pedro L Alonso,

The Role of Mass Drug Administration of Antimalarials. ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Cost-Effectiveness of Focal Mass Drug Administration and Mass Drug Administration with Dihydroartemisinin-Piperaquine for Malaria Prevention in Southern Province, Zambia: Results of a Community-Randomized Controlled Trial.

Joshua O Yukich, Callie Scott, Kafula Silumbe, Bruce A Larson, Adam Bennett, Timothy P Finn, Busiku Hamainza, Ruben O Conner, Travis R Porter, Joseph Keating, Richard W Steketee, Thomas P Eisele, John M Miller,

Community-wide administration of antimalarial drugs in therapeutic doses is a potential tool to prevent malaria infection and reduce the malaria parasite reservoir. To measure the effectiveness and cost of using the antimalarial drug combination dihydroartemisinin-piperaquine (DHAp) through different community-wide distribution strategies, Zambia's National Malaria Control Centre conducted a three-armed community-randomized ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Pyrethroid and Carbamate Resistance in Anopheles funestus Giles along Lake Kariba in Southern Zambia.

Javan Chanda, Kochelani Saili, Foustina Phiri, Jennifer C Stevenson, Mulenga Mwenda, Sandra Chishimba, Conceptor Mulube, Brenda Mambwe, Christopher Lungu, Duncan Earle, Adam Bennett, Thomas P Eisele, Mulakwa Kamuliwo, Richard W Steketee, Joseph Keating, John M Miller, Chadwick H Sikaala,

Whereas data on insecticide resistance and its underlying mechanisms exist for parts of Zambia, data remain limited in the southern part of the country. This study investigated the status of insecticide resistance, metabolic mechanisms, and parasite infection in Anopheles funestus along Lake Kariba in southern Zambia. Indoor-resting mosquitoes were collected ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Prevalence of Asymptomatic and/or Low-Density Malaria Infection among High-Risk Groups in Peninsular Malaysia.

Naqib Rafieqin Noordin, Phone Youth Lee, Fatma Diyana Mohd Bukhari, Mun Yik Fong, Mohd Hafizi Abdul Hamid, Jenarun Jelip, Rose Nani Mudin, Yee Ling Lau,

Asymptomatic and/or low-density malaria infection has been acknowledged as an obstacle to achieving a malaria-free country. This study aimed to determine the prevalence of asymptomatic and/or low-density malaria infection in previously reported malarious localities using nested PCR in four states, namely, Johor, Pahang, Kelantan, and Selangor, between June 2019 and ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Impact of Different Strategies for Delivering Supplemental Zinc on Selected Fecal Markers of Environmental Enteric Dysfunction among Young Laotian Children: A Randomized Controlled Trial.

Guy-Marino Hinnouho, K Ryan Wessells, Maxwell A Barffour, Somphou Sayasone, Charles D Arnold, Sengchanh Kounnavong, Sonja Y Hess,

The objective of this study was to assess the impact of different strategies for delivering supplemental zinc on fecal myeloperoxidase (MPO), neopterin (NEO), and calprotectin (CAL) among young Laotian children. In a double-blind controlled trial, children aged 6-23 months were randomized to receive either daily preventive zinc (PZ) tablets (7 ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Out-of-Pocket Costs for Patients Diagnosed with Tuberculosis in Different Healthcare Settings in Bandung, Indonesia.

Susan M McAllister, Bony Wiem Lestari, Trudy Sullivan, Panji Fortuna Hadisoemarto, Nur Afifah, Rosye Arosdiani Apip, Megan Murray, Philip C Hill, Bachti Alisjahbana,

Costs related to tuberculosis (TB) can impose a significant burden on patients and their families and create barriers to diagnosis and treatment. Our study aimed to quantify out-of-pocket costs expended by TB patients in Bandung, Indonesia. This cross-sectional study recruited adults with TB from community health centers (CHCs), public and ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Predictors of Loss to Follow-Up among Men with Tuberculosis in Puducherry and Tamil Nadu, India.

Thomas J Zhou, Subitha Lakshminarayanan, Sonali Sarkar, Selby Knudsen, C Robert Horsburgh, Muthuraj Muthaiah, Carolyn K Kan, Padmini Salgame, Jerrold J Ellner, Gautam Roy, Helen E Jenkins, Natasha S Hochberg,

Identifying predictors of loss to follow-up (LTFU; treatment lapse ≥ 2 months) among people with tuberculosis (TB) may assist programmatic efforts in controlling the spread of TB. Newly diagnosed smear-positive TB patients were enrolled in the Regional Prospective Observational Research for TB study in Puducherry and Tamil Nadu, India. Treatment ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, :]

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Lichenoid Skin Nodules as Presenting Feature of Necrotic Erythema Nodosum Leprosum in Leprosy.

Akanksha Kaushik, Sunil Dogra, Tarun Narang,

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, 103(1):9]

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Impact of Different Mass Drug Administration Strategies for Gaining and Sustaining Control of Schistosoma mansoni and Schistosoma haematobium Infection in Africa.

Charles H King, Nupur Kittur, Sue Binder, Carl H Campbell, Eliézer K N'Goran, Aboulaye Meite, Jürg Utzinger, Annette Olsen, Pascal Magnussen, Safari Kinung'hi, Alan Fenwick, Anna E Phillips, Pedro H Gazzinelli-Guimaraes, Neerav Dhanani, Josefo Ferro, Diana M S Karanja, Pauline N M Mwinzi, Susan P Montgomery, Ryan E Wiegand, William Evan Secor, Amina A Hamidou, Amadou Garba, Daniel G Colley,

This report summarizes the design and outcomes of randomized controlled operational research trials performed by the Bill & Melinda Gates Foundation-funded Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) from 2009 to 2019. Their goal was to define the effectiveness and test the limitations of current WHO-recommended schistosomiasis control protocols ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, 103(1_Suppl):14-23]

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Schistosomiasis Consortium for Operational Research and Evaluation: Mission Accomplished.

N Robert Bergquist,

The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE), a program focusing on schistosomiasis control in sub-Saharan Africa between 2008 and 2019, investigated ways to improve coverage and efficacy of ongoing chemotherapy programs and concluded that because of continued transmission, mass distribution of praziquantel cannot eliminate the disease without complementary ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, 103(1_Suppl):1-4]

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