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Response to Parental Triamcinolone in Severe Asthma: A Useful Induced Phenotype for Clinicians?

William J Calhoun, Alejandro Villasante-Tezanos,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Triple Therapy Trials for COPD: Methodological Considerations in the Mortality Effect.

José Luis López-Campos, Alberto Fernández-Villar, Alberto Ruano-Ravina,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Mortality in ETHOS, a Question of "Power".

Paola Rogliani, Luigino Calzetta,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Reply to: López-Campos et al, and to Rogliani and Calzetta.

Fernando J Martinez, Patrick Darken, Paul Dorinsky,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Very Late Antigen-4: A Novel Receptor for Club Cell Secretory Protein 16 to Control Inflammation.

Hong Wei Chu, Niccolette Schaunaman,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Professor Pangloss and the Pangenome: Does Staphylococcus aureus Have the Best of All Possible Worlds?

Freya Harrison, Alan R Smyth,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Where is the Cystic Fibrosis Transmembrane Conductance Regulator?

Pascal Barbry, Brice Marcet, Ignacio Caballero,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Effect of Lowering Tidal Volume on Mortality in ARDS Varies with Respiratory System Elastance.

Ewan C Goligher, Eduardo L V Costa, Christopher J Yarnell, Laurent J Brochard, Thomas E Stewart, George Tomlinson, Roy G Brower, Arthur S Slutsky, Marcelo P B Amato,

Rationale If the risk of ventilator-induced lung injury in acute respiratory distress syndrome is causally determined by driving pressure rather than tidal volume, then the effect of ventilation with lower tidal volumes on mortality would be predicted to vary according to respiratory system elastance. Objectives To determine whether the mortality ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

Cited: 0 times

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Reply to: Triple Therapy Trials for COPD: Methodological Considerations in the Mortality Effect.

David A Lipson, MeiLan K Han, Robert Wise, Fernando J Martinez, ,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Reply to: Are Ground Glass Opacities on HRCT a Manifestation of Airway Disease?

Martine Remy-Jardin, Kevin C Wilson, Ganesh Raghu,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Monocyte Count as a Prognostic Biomarker in Patients with Idiopathic Pulmonary Fibrosis.

Michael Kreuter, Joyce S Lee, Argyrios Tzouvelekis, Justin M Oldham, Philip L Molyneaux, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler, Toby M Maher,

<b>Rationale:</b> There is an urgent need for simple, cost-effective prognostic biomarkers for idiopathic pulmonary fibrosis (IPF); biomarkers that show potential include monocyte count. <b>Objectives:</b> We used pooled data from pirfenidone and interferon gamma-1b trials to explore the association between monocyte count and prognosis in patients with IPF. <b>Methods:</b> This retrospective ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Effect of Simulated Obstructive Apnea on Thoracic Fluid Volume and Airway Narrowing in Asthma.

Xiaoshu Cao, T Douglas Bradley, Swati A Bhatawadekar, Shumit Saha, Susan M Tarlo, Matthew B Stanbrook, Mark D Inman, Khadija Rana, Ronald J Dandurand, Azadeh Yadollahi,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Are Ground Glass Opacities on HRCT a Manifestation of Airway Disease?

Onofre Morán-Mendoza, Mohamed Khalil,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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A Note on Common Apathy Versus Hypoactive Delirium in Critical Illness.

Jan N M Schieveld, Jacqueline J M H Strik,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Spring in New York.

Jeremy R Beitler,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Non-invasive Surrogate Markers of PH are Associated with Poor Survival in Lung Cancer Patients.

Bastian Eul, Michael Cekay, Soni Savai Pullamsetti, Khodr Tello, Jochen Wilhelm, Stefan Gattenlöhner, Ulf Sibelius, Friedrich Grimminger, Werner Seeger, Rajkumar Savai,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Entire Bilateral Kidneys Enhanced by Air-contrast after Ventilation-induced Alveolar Rupture.

Hsin Tseng, Alexander Lee Wang, Hsin-Ti Lin, Chi Chan Lee, Wei-Cheng Chen,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Antigen-specific T Cell Activation Distinguishes Between Recent and Remote Tuberculosis Infection.

Cheleka A M Mpande, Munyaradzi Musvosvi, Virginie Rozot, Boitumelo Mosito, Timothy D Reid, Constance Schreuder, Tessa Lloyd, Nicole Bilek, Huang Huang, Gerlinde Obermoser, Mark M Davis, Morten Ruhwald, Mark Hatherill, Thomas J Scriba, Elisa Nemes, ,

<h4>Rationale</h4>Current diagnostic tests fail to identify individuals at higher risk of progression to tuberculosis disease, such as those with recent Mycobacterium tuberculosis infection, who should be prioritized for targeted preventive treatment.<h4>Objectives</h4>To define a blood-based biomarker, measured with a simple flow cytometry assay, that can stratify different stages of tuberculosis infection ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Congenital Tracheo-esophageal Fistula in an Adult.

Seshiru Nakazawa, Toshiki Yajima, Ken Shirabe,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Comparative Effectiveness of Protective Ventilation Strategies for Moderate and Severe ARDS: Network Meta-Analysis.

Sachin Sud, Jan O Friedrich, Neill Kj Adhikari, Eddy Fan, Niall D Ferguson, Gordon Guyatt, Maureen O Meade,

<h4>Rationale</h4>Choosing the best ventilation strategy for acute respiratory distress syndrome (ARDS) is complex, yet highly relevant to clinicians during a respiratory pandemic.<h4>Objectives</h4>To compare the effects of low tidal volumes (Vt), high Vt, high positive end-expiratory pressure (high PEEP), prone ventilation, high frequency oscillation (HFO), and venovenous extracorporeal membrane oxygenation (VV ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Similarity of Lung Ultrasound Image in Patients with COVID-19 and COVID-like Illnesses.

Natalia Buda, Jolanta Cylwik, Renata Kwiecińska,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Positive End-Expiratory Pressure, Pleural Pressure, and Regional Compliance During Pronation: An Experimental Study.

Bhushan H Katira, Kohei Osada, Doreen Engelberts, Luca Bastia, L Felipe Damiani, Xuehan Li, Han Chen, Takeshi Yoshida, Marcelo B P Amato, Niall D Ferguson, Martin Post, Brian P Kavanagh, Laurent J Brochard,

<h4>Rationale</h4>The physiological basis of lung protection and the impact of PEEP during pronation in ARDS are not fully elucidated.<h4>Objectives</h4>To compare pleural pressure (Ppl) gradient, ventilation distribution and regional compliance between dependent and non-dependent lung, and investigate the effect of PEEP during supination and pronation.<h4>Methods</h4>We used a 2-hit model of lung ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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Respiratory Effects of Sedentary Ozone Exposure at the 70 ppb National Ambient Air Quality Standard: A Randomized Clinical Trial.

Michelle L Hernandez, Sally Ivins, Kelly Chason, Allison J Burbank, Meghan E Rebuli, Aaron Kobernick, Stephen A Schworer, Haibo Zhou, Neil E Alexis, David B Peden,

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

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The Sleep Apnea-specific Pulse Rate Response Predicts Cardiovascular Morbidity and Mortality.

Ali Azarbarzin, Scott A Sands, Magdy Younes, Luigi Taranto-Montemurro, Tamar Sofer, Daniel Vena, Raichel M Alex, Sang-Wook Kim, Daniel J Gottlieb, David P White, Susan Redline, Andrew Wellman,

<h4>Rational</h4>Randomized controlled trials have been unable to detect a cardiovascular benefit of continuous positive airway pressure (CPAP) in unselected patients with obstructive sleep apnea (OSA). We hypothesize that deleterious cardiovascular outcomes are concentrated in a subgroup of patients with heightened apnea/hypopnea-related pulse rate response.<h4>Methods</h4>We measured the pulse rate response to ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

Cited: 0 times

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Plasma Soluble Suppression of Tumerogenicity-2 Associates with Ventilator Liberation in Acute Hypoxemic Respiratory Failure.

Jehan Alladina, Sean D Levy, Josalyn L Cho, Kelsey L Brait, Sowmya R Rao, Alexander Camacho, Kathryn A Hibbert, R Scott Harris, Benjamin D Medoff, James L Januzzi, B Taylor Thompson, Ednan K Bajwa,

<h4>Rationale</h4>Standard physiologic assessments of extubation readiness in patients with acute hypoxemic respiratory failure (AHRF) may not reflect lung injury resolution and could adversely affect clinical decision-making and patient outcomes.<h4>Objectives</h4>We hypothesized that elevations in inflammatory plasma biomarkers soluble suppression of tumerogenicity-2 (sST2) and interleukin-6 (IL-6) indicate ongoing lung injury in AHRF ... Read more >>

Am J Respir Crit Care Med (American journal of respiratory and critical care medicine)
[2021, :]

Cited: 0 times

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