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DMSO reduces the cytotoxicity of anticancer ruthenium complex KP1019 in yeast.

Jonathan Davis, Anne Cetto, Mary Campbell, Seth Scoggins, Laura Stultz, Pamela Hanson,

Low solubility in aqueous solutions is a significant limitation of the otherwise promising anticancer ruthenium complex KP1019. In laboratory studies, this challenge is often overcome by using DMSO to help drive the drug into solution. Since DMSO was previously shown to alter the bioactivity of platinum-based chemotherapeutics, here we examine ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Caenorhabditis Intervention Testing Program: the farnesoid X receptor agonist obeticholic acid does not robustly extend lifespan in nematodes.

Mackenzie L Morshead, Christine A Sedore, E Grace Jones, David Hall, W Todd Plummer, Theo Garrett, Mark Lucanic, Max Guo, Monica Driscoll, Patrick C Phillips, Gordon Lithgow,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 1 time

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Caenorhabditis Intervention Testing Program: the creatine analog β-guanidinopropionic acid does not extend lifespan in nematodes.

Anna L Coleman-Hulbert, Erik Johnson, Christine A Sedore, Stephen A Banse, Max Guo, Monica Driscoll, Gordon J Lithgow, Patrick C Phillips,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 3 times

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Corrigendum: 10.17912/micropub.biology.000131.

[This corrects the article DOI: 10.17912/micropub.biology.000131.]. ... Read more >>

MicroPubl Biol (microPublication biology)
[2019, 2019:]

Cited: 0 times

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Corrigendum: Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes. microPublication Biology July 3, 2019. 10.17912/micropub.biology.000131.

[This corrects the article DOI: 10.17912/micropub.biology.000131.]. ... Read more >>

MicroPubl Biol (microPublication biology)
[2019, 2019:]

Cited: 0 times

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Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes.

Anna L Coleman-Hulbert, Erik Johnson, Christine A Sedore, Stephen A Banse, Max Guo, Monica Driscoll, Gordon J Lithgow, Patrick C Phillips,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

Cited: 3 times

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Stroke recovery enhancing therapies: lessons from recent clinical trials.

Andreas Rogalewski, Wolf-Rüdiger Schäbitz,

Poststroke recovery processes include restoration or compensation of function, respectively functions initially lost or new functions acquired after an injury. Therapeutic interventions can enhance these processes and/or reduce processes impeding regeneration. Numerous experimental studies suggest great opportunities for such treatments, but the results from recent large clinical trials using neuromodulators ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):717-720]

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Modeling Multicomponent Interventions in Network Meta-Analysis.

Areti Angeliki Veroniki, Georgios Seitidis, Stavros Nikolakopoulos, Marta Ballester, Jessica Beltran, Monique Heijmans, Dimitris Mavridis,

There is a rapid increase in trials assessing healthcare interventions consisting of a combination of drugs (polytherapies) or multiple components. In the latter type of interventions (also known as complex interventions), the aspect of complexity is of paramount importance. For example, nonpharmacological interventions, such as psychological interventions or self-management interventions, ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2345:245-261]

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Survival outcomes and adverse events in patients with chronic kidney disease after coronary artery bypass grafting and percutaneous coronary intervention: a meta-analysis of propensity score-matching studies.

Ye-Gui Yang, Nuo Li, Meng-Hua Chen,

<h4>Background</h4>The present meta-analysis of propensity score-matching studies aimed to compare the long-term survival outcomes and adverse events associated with coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in patients with chronic kidney disease (CKD).<h4>Methods</h4>Electronic databases were searched for studies comparing CABG and PCI in patients with CKD. The ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):606-616]

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CRISPR/Cas9-Mediated Genetic Engineering to Generate a Disease Model Prairie Vole, Based on Species-Optimized Assisted Reproductive Technology.

Kengo Horie, Katsuhiko Nishimori,

Social and prosocial behaviors, including communication, social bonding, and affiliation, parental behaviors, and empathy are key features of a highly social mammalian species. However, the neuronal mechanism in the brain underlying these behaviors remains unclear because of limited information on the social and prosocial behavioral levels in rodent models generally ... Read more >>

Methods Mol Biol (Methods in molecular biology (Clifton, N.J.))
[2022, 2384:139-152]

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Effectiveness of Structured Physical Activity Interventions Through the Evaluation of Physical Activity Levels, Adoption, Retention, Maintenance, and Adherence Rates: A Systematic Review and Meta-Analysis.

Nadja Willinger, James Steele, Lou Atkinson, Gary Liguori, Alfonso Jimenez, Steve Mann, Elizabeth Horton,

<h4>Background</h4>Structured physical activity (PA) interventions (ie, intentionally planned) can be implemented in a variety of facilities, and therefore can reach a large proportion of the population. The aim of the authors was to summarize the effectiveness of structured interventions upon PA outcomes, in addition to proportions of individuals adopting and maintaining ... Read more >>

J Phys Act Health (Journal of physical activity & health)
[2021, 18(1):116-129]

Cited: 1 time

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Participants' experiences and impressions of a group-based positive psychology intervention programme for rural adults in Ghana.

Richard Appiah, Angelina Wilson Fadiji, Marie P Wissing, Lusilda Schutte,

<b>Introduction</b>: There is growing evidence that group-based mental health intervention programmes can encourage the development of peer support, psychosocial skills, and collaborative therapeutic relationships with longer lasting effects. This study explored participants' experiences of, perceived benefits of, and recommendations to improve a 10-session group-based multicomponent positive psychology intervention (mPPI)-the <i>Inspired Life ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1891760]

Cited: 1 time

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Effectiveness of multimodal nutrition interventions during pregnancy to achieve 2009 Institute of Medicine gestational weight gain guidelines: a systematic review and meta-analysis.

Andrew R Beauchesne, Kelly Copeland Cara, Jiawen Chen, Qisi Yao, Laura Paige Penkert, Wenfang Yang, Mei Chung,

<h4>Background</h4>In 2009, the Institute of Medicine (IOM) published a revision to its 1990 recommendations on gestational weight gain (GWG). The objective of this review is to update a previous systematic review and meta-analysis to evaluate the effectiveness of nutrition interventions in achieving recommended GWG.<h4>Methods</h4>We conducted updated literature searches in MEDLINE<sup>®</sup> ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1179-1197]

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Suppressed inflammation in obese children induced by a high-fiber diet is associated with the attenuation of gut microbial virulence factor genes.

Hui Li, Guojun Wu, Liping Zhao, Menghui Zhang,

In our previous study, a gut microbiota-targeted dietary intervention with a high-fiber diet improved the immune status of both genetically obese (Prader-Willi Syndrome, PWS) and simple obese (SO) children. However, PWS children had higher inflammation levels than SO children throughout the trial, the gut microbiota of the two cohorts was ... Read more >>

Virulence (Virulence)
[2021, 12(1):1754-1770]

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Storying My Lifestyle Change: How Breast Cancer Survivors Experience and Reflect on Their Participation in a Pilot Healthy Lifestyle Intervention.

Shira J Yufe, Karen D Fergus, Dana A Male,

<b>Purpose</b>: Healthy lifestyle interventions after breast cancer treatment have generally been studied in terms of weight-loss outcomes, which leaves a gap in our understanding of the phenomenological experience of such programs. Our knowledge of <i>how</i> or <i>why</i> women recovering from breast cancer engage or do not engage in these programs ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1864903]

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Primary care practice-based care management for chronically ill patients (PraCMan) in German healthcare: Outcome of a propensity-score matched cohort study.

Jonas D Senft, Tobias Freund, Michel Wensing, Simon Schwill, Regina Poss-Doering, Joachim Szecsenyi, Gunter Laux,

<h4>Background</h4>Growing prevalence of chronic diseases is a rising challenge for healthcare systems. The Primary Care Practice-Based Care Management (PraCMan) programme is a comprehensive disease management intervention in primary care in Germany aiming to improve medical care and to reduce potentially avoidable hospitalisations for chronically ill patients.<h4>Objectives</h4>This study aimed to assess ... Read more >>

Eur J Gen Pract (The European journal of general practice)
[2021, 27(1):228-234]

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Health promotion interventions supporting Indigenous healthy ageing: a scoping review.

Sarah Oosman, Christine Nisbet, Liris Smith, Sylvia Abonyi,

Aging well is a priority in Canada and globally, particularly for older Indigenous adults experiencing an increased risk of chronic conditions. Little is known about health promotion interventions for older Indigenous adults and most literature is framed within Eurocentric paradigms that are not always relevant to Indigenous populations. This scoping ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1950391]

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Effects of a multimodal exercise protocol on functional outcomes, epigenetic modulation and brain-derived neurotrophic factor levels in institutionalized older adults: a quasi-experimental pilot study.

Iasmin Fraga, Camila Weber, Wériton Baldo Galiano, Lucio Iraci, Mariana Wohlgemuth, Gabriela Morales, Camila Cercato, Juliana Rodriguez, Daniela Pochmann, Caroline Dani, Pérsia Menz, Adriane Dal Bosco, Viviane Rostirola Elsner,

Epigenetic changes have been shown to be associated with both aging process and aging-related diseases. There is evidence regarding the benefits of physical activity on the functionality, cognition, and quality of life of institutionalized older adults, however, the molecular mechanisms involved are not elucidated. The purpose of this pilot study ... Read more >>

Neural Regen Res (Neural regeneration research)
[2021, 16(12):2479-2485]

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Contemporary impact of circadian symptom-onset patterns of acute ST-Segment elevation myocardial infarction on long-term outcomes after primary percutaneous coronary intervention.

Hui Peng, Zhijun Sun, Beibing Di, Xiaosong Ding, Hui Chen, Hongwei Li,

<h4>Background</h4>Daytime variation with regard to onset time of ST-elevation myocardial infarction (STEMI) symptoms has been observed. Nevertheless, with the advanced medical therapy, it is not uncertainty if a similar circadian pattern of STEMI symptom onset occurs, as well as its possible impact on clinical outcomes. Few long-term data are available. ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):247-256]

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Diversity Interventions in the Classroom: From Resistance to Action.

Dustin B Thoman, Melo-Jean Yap, Felisha A Herrera, Jessi L Smith,

What goes into faculty decisions to adopt a classroom intervention that closes achievement gaps? We present a theoretical model for understanding possible resistance to and support for implementing and sustaining a diversity-enhancing classroom intervention. We propose, examine, and refine a "diversity interventions-resistance to action" model with four key inputs that ... Read more >>

CBE Life Sci Educ (CBE life sciences education)
[2021, 20(4):ar52]

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Nurses' experiences of serving as a communication guide and supporting the implementation of a communication intervention in the intensive care unit.

Anna Holm, Veronika Karlsson, Pia Dreyer,

<h4>Purpose</h4>: To explore the experience of serving as a nurse communication guide, supporting the bottom-up implementation of a multi-component communication intervention prototype in the intensive care unit.<h4>Methods</h4>: The overall frame was Complex Interventions, and the study was conducted within the phenomenological-hermeneutic tradition. Semi-structured telephone interviews were conducted with eight nurse ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1971598]

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Health-related integration interventions for migrants by civil society organizations: an integrative review.

Pelle Pelters, Eva-Carin Lindgren, Catrine Kostenius, Marie Lydell, Krister Hertting,

<b>Purpose</b>: Migrants are a vulnerable group concerning health and integration. Civil society organizations are deemed important for the integration and health of migrants and have been encouraged to help. This study explored health and acculturation, as expressed in research into health-related integration interventions for migrant groups provided by civil society ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2021, 16(1):1927488]

Cited: 1 time

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Can changes to improve person-centred maternity care be spread across public health facilities in Uttar Pradesh, India?

May Sudhinaraset, Katie Giessler, Michelle Kao Nakphong, Kali Prosad Roy, Ananta Basudev Sahu, Kovid Sharma, Dominic Montagu, Cathy Green,

Poor quality person-centred maternity care (PCMC) leads to delays in care and adverse maternal and newborn outcomes. This study describes the impact of spreading a Change Package, or interventions that other health facilities had previously piloted and identified as successful, to improve PCMC in public health facilities in Uttar Pradesh, ... Read more >>

Sex Reprod Health Matters (Sexual and reproductive health matters)
[2021, 29(1):1-15]

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School professionals committed to student well-being.

Anna Onnela, Tuula Hurtig, Hanna Ebeling,

The northern provinces of Finland are mostly not densely populated, with long distances to healthcare services. This creates a challenge for how to reach all children and adolescents with mental health services. In order to assess the effectiveness of school-based mental health promotion interventions, it is essential to understand the ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1873589]

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Positive-word stimuli via a smartphone application have no immediate-term effects on multi-directional reach ability in standing position: a randomized controlled trial.

Kenta Azukizawa, Kodai Hirose, Yuta Morigami, Naoki Higashi, Hiroyuki Uchida, Kazuki Hirao,

<h4>Objectives</h4>The purpose of the study was to examine the immediate-term effect of positive-word stimuli via a smartphone application on the multi-directional reach ability in standing position in young adults.<h4>Methods</h4>This study was an immediate-term, assessor-blinded, two-arm, parallel-group, randomized controlled trial among young adults recruited from one university in Japan. Participants were ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):1402-1409]

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