Full Text Journal Articles about
Interstitial Nonidiopathic Pulmonary Fibrosis

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Telomeropathy in Chronic Hypersensitivity Pneumonitis.

Demosthenes Bouros, Argyrios Tzouvelekis,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2019, 200(9):1086-1087]

Cited: 0 times

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Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.

Felix Chua, Sujal R Desai, Andrew G Nicholson, Anand Devaraj, Elisabetta Renzoni, Alexandra Rice, Athol U Wells,

Pleuroparenchymal fibroelastosis (PPFE) is an unusual pulmonary disease with unique clinical, radiological, and pathological characteristics. Designated a rare idiopathic interstitial pneumonia in 2013, its name refers to a combination of fibrosis involving the visceral pleura and fibroelastotic changes predominating in the subpleural lung parenchyma. Although a number of disease associations ... Read more >>

Ann Am Thorac Soc (Annals of the American Thoracic Society)
[2019, 16(11):1351-1359]

Cited: 0 times

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Remember Me? The Bone Marrow in Pulmonary Fibrosis.

Sunad Rangarajan, Victor J Thannickal,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2019, 200(8):959-960]

Cited: 0 times

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Subclinical Interstitial Lung Abnormalities: Lumping and Splitting Revisited.

Simon L F Walsh, Luca Richeldi,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2019, 200(2):121-123]

Cited: 1 time

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Unclassifiable interstitial lung disease: from phenotyping to possible treatments.

Sabina A Guler, Christopher J Ryerson,

PURPOSE OF REVIEW:Accurate diagnosis of interstitial lung diseases (ILDs) can be challenging, and a substantial percentage of ILD patients remain unclassifiable even after thorough assessment by an experienced multidisciplinary team. In this review, we summarize the recent literature on the definition, prevalence, diagnosis, treatment, and prognosis of unclassifiable ILD, and ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2018, 24(5):461-468]

Cited: 1 time

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Clinical implications of telomere dysfunction in lung fibrosis.

Maria Molina-Molina, Raphael Borie,

PURPOSE OF REVIEW:Telomere attrition has been proposed as one of the aging hallmarks in pulmonary fibrosis. Telomere shortening and telomerase gene mutations have been widely evaluated in recent years. Reduced telomere length may be identified in a quarter of patients with sporadic idiopathic pulmonary fibrosis (IPF) and half of those ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2018, 24(5):440-444]

Cited: 4 times

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Utility of Routine Spirometry Measures for Surveillance of Idiopathic Subglottic Stenosis.

Delaney J Carpenter, Sergio Ferrante, Stephen R Bakos, Matthew S Clary, Alexander H Gelbard, James J Daniero,

Importance:Because of the recurrent nature of idiopathic subglottic stenosis, routine follow-up is necessary for monitoring progression of stenosis. However, no easily accessible, standardized objective measure exists to monitor disease progression. Objective:To determine whether peak expiratory flow (PEF) can be used as a reliable and easily accessible biometric indicator of disease ... Read more >>

JAMA Otolaryngol Head Neck Surg (JAMA otolaryngology-- head & neck surgery)
[2019, 145(1):21-26]

Cited: 1 time

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Association between a Single Nucleotide Polymorphism in the 3'-UTR of ARHGEF18 and the Risk of Nonidiopathic Pulmonary Arterial Hypertension in Chinese Population.

Ding Li, Yan Sun, Xiaochao Kong, Changxing Luan, Youjia Yu, Feng Chen, Peng Chen,

ARHGEF18 has been identified as upregulated in the lung tissues of rat models of pulmonary artery hypertension introduced by hypoxia or monocrotaline (MCT). We used online SNP function prediction tools to screen the candidate SNPs that might be associated with the regulation of the ARHGEF18 expression. The result suggested that ... Read more >>

Dis. Markers (Disease markers)
[2018, 2018:2461845]

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Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias: the time is now (?).

Michael Kreuter, Julia Wälscher, Jürgen Behr,

Therapeutic advances in the management of idiopathic pulmonary fibrosis (IPF) has led to improved outcomes with the use of the antifibrotic agents pirfenidone and nintedanib, with a number of randomized studies demonstrating benefits in slowing disease progression in IPF. However, treatment of other fibrosing interstitial lung diseases (ILD) remains challenging.Observational ... Read more >>

Curr Opin Pulm Med (Current opinion in pulmonary medicine)
[2017, 23(5):418-425]

Cited: 3 times

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Alpha-1 Antitrypsin Levels and Polymorphisms in Interstitial Lung Diseases.

Nalan Demir, Özlem Erçen Diken, Halil Gürhan Karabulut, Demet Karnak, Oya Kayacan,

BACKGROUND/AIM:Alpha-1 antitrypsin deficiency may be a potential predisposing factor for interstitial lung fibrosis. We investigated alpha-1 antitrypsin levels and its polymorphisms in patients with interstitial lung disease. MATERIALS AND METHODS:A total of 103 interstitial lung disease patients were compared. RESULTS:The mean alpha-1 antitrypsin level in idiopathic interstitial pneumonia patients was ... Read more >>

Turk J Med Sci (Turkish journal of medical sciences)
[2017, 47(2):476-482]

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Characterization of human PDGFR-β-positive pericytes from IPF and non-IPF lungs.

Carole L Wilson, Sarah E Stephenson, Jean Paul Higuero, Carol Feghali-Bostwick, Chi F Hung, Lynn M Schnapp,

Pericytes are key regulators of the microvasculature through their close interactions with the endothelium. However, pericytes play additional roles in tissue homeostasis and repair, in part by transitioning into myofibroblasts. Accumulation of myofibroblasts is a hallmark of fibrotic diseases such as idiopathic pulmonary fibrosis (IPF). To understand the contribution and ... Read more >>

Am. J. Physiol. Lung Cell Mol. Physiol. (American journal of physiology. Lung cellular and molecular physiology)
[2018, 315(6):L991-L1002]

Cited: 2 times

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Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts.

Saeid Ghavami, Behzad Yeganeh, Amir A Zeki, Shahla Shojaei, Nicholas J Kenyon, Sean Ott, Afshin Samali, John Patterson, Javad Alizadeh, Adel Rezaei Moghadam, Ian M C Dixon, Helmut Unruh, Darryl A Knight, Martin Post, Thomas Klonisch, Andrew J Halayko,

Idiopathic pulmonary fibrosis (IPF) is a lethal fibrotic lung disease in adults with limited treatment options. Autophagy and the unfolded protein response (UPR), fundamental processes induced by cell stress, are dysregulated in lung fibroblasts and epithelial cells from humans with IPF. Human primary cultured lung parenchymal and airway fibroblasts from ... Read more >>

Am. J. Physiol. Lung Cell Mol. Physiol. (American journal of physiology. Lung cellular and molecular physiology)
[2018, 314(3):L493-L504]

Cited: 12 times

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Factors associated with the 6-minute walk distance in patients with systemic sclerosis.

Sébastien Sanges, Jonathan Giovannelli, Vincent Sobanski, Sandrine Morell-Dubois, Hélène Maillard, Marc Lambert, Céline Podevin, Nicolas Lamblin, Pascal De Groote, Jean-François Bervar, Thierry Perez, Régis Matran, Martine Rémy-Jardin, Pierre-Yves Hatron, Éric Hachulla, David Launay,

There is an ongoing debate regarding the relevance of the 6-minute walking distance (6MWD) in systemic sclerosis (SSc) assessment, widely used as a usual test in these patients as well as an outcome measure in clinical trials. In this work, we aimed to assess the associations between the 6MWD and ... Read more >>

Arthritis Res. Ther. (Arthritis research & therapy)
[2017, 19(1):279]

Cited: 0 times

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Exploring Clinical and Epidemiological Characteristics of Interstitial Lung Diseases: Rationale, Aims, and Design of a Nationwide Prospective Registry--The EXCITING-ILD Registry.

Michael Kreuter, Felix J F Herth, Margarethe Wacker, Reiner Leidl, Andreas Hellmann, Michael Pfeifer, Jürgen Behr, Sabine Witt, Dagmar Kauschka, Marcus Mall, Andreas Günther, Philipp Markart,

Despite a number of prospective registries conducted in past years, the current epidemiology of interstitial lung diseases (ILD) is still not well defined, particularly regarding the prevalence and incidence, their management, healthcare utilisation needs, and healthcare-associated costs. To address these issues in Germany, a new prospective ILD registry, "Exploring Clinical ... Read more >>

Biomed Res Int (BioMed research international)
[2015, 2015:123876]

Cited: 4 times

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Fibrosis: ultimate and proximate causes.

Victor J Thannickal, Yong Zhou, Amit Gaggar, Steven R Duncan,

Fibrotic disorders account for an increasing burden of disease-associated morbidity and mortality worldwide. Although numerous risk factors have been recognized, the etiologies of many of these clinical syndromes have not been identified, and they are often termed idiopathic or cryptogenic. Here, we provide an evolutionary perspective on fibrosis aimed at ... Read more >>

J. Clin. Invest. (The Journal of clinical investigation)
[2014, 124(11):4673-4677]

Cited: 69 times

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Limitations to the 6-minute walk test in dermatomyositis with interstitial lung disease in comparison with idiopathic interstitial pneumonia.

Fujiko Someya, Naoki Mugii,

Although the relationship between muscle strength and exercise capacity has been demonstrated in dermatomyositis without lung dysfunction, little is known about the association between exercise capacity and interstitial lung disease in dermatomyositis. Eleven patients with dermatomyositis with interstitial lung disease without the manifestation of muscle weakness and 12 patients with ... Read more >>

Clin Med Insights Circ Respir Pulm Med (Clinical medicine insights. Circulatory, respiratory and pulmonary medicine)
[2013, 7:1-6]

Cited: 2 times

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Systematic review of postradiotherapy bronchiolitis obliterans organizing pneumonia in women with breast cancer.

Gary R Epler, Eileen M Kelly,

Radiation therapy for breast cancer has been implicated in the development of bronchiolitis obliterans organizing pneumonia (BOOP). This inflammatory lung disorder was first noted in 1983, and there have been numerous reports of BOOP occurring in women who have had radiation therapy for breast cancer since 1995. This study was ... Read more >>

Oncologist (The oncologist)
[2014, 19(12):1216-1226]

Cited: 9 times

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Diffuse alveolar damage: a common phenomenon in progressive interstitial lung disorders.

Riitta Kaarteenaho, Vuokko L Kinnula,

It has become obvious that several interstitial lung diseases, and even viral lung infections, can progress rapidly, and exhibit similar features in their lung morphology. The final histopathological feature, common in these lung disorders, is diffuse alveolar damage (DAD). The histopathology of DAD is considered to represent end stage phenomenon ... Read more >>

Pulm Med (Pulmonary medicine)
[2011, 2011:531302]

Cited: 11 times

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Severe pulmonary hypertension in idiopathic nonspecific interstitial pneumonia.

Robert W Hallowell, Robert M Reed, Mostafa Fraig, Maureen R Horton, Reda E Girgis,

Pulmonary hypertension (PH) is a common complication of interstitial lung disease (ILD), particularly in idiopathic pulmonary fibrosis (IPF) and ILD associated with connective tissue disease, where the underlying pathology is often a nonspecific interstitial pneumonia (NSIP) pattern. The degree of PH in ILD is typically mild to moderate and radiographic ... Read more >>

Pulm Circ (Pulmonary circulation)
[2012, 2(1):101-106]

Cited: 6 times

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Cases non-specific interstitial pneumonia and hypersensitivity pneumonia: A new pathologic diagnosis or overlap syndrome.

S F Tafti, A Cheraghvandi, B Mokri, F Talischi,

ATS/ERS evaluation of ILD's has recently considered NSIP as a single entity and it has historically been considered a provisional diagnosis. As more cases are reviewed, pathologic characteristics may become more precise with less overlap and help in diagnosis of complex cases. Here, we present a series of cases of ... Read more >>

Respir Med Case Rep (Respiratory medicine case reports)
[2012, 5:45-48]

Cited: 0 times

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Prospective, observational study of voriconazole therapeutic drug monitoring among lung transplant recipients receiving prophylaxis: factors impacting levels of and associations between serum troughs, efficacy, and toxicity.

Dimitra Mitsani, M Hong Nguyen, Ryan K Shields, Yoshiya Toyoda, Eun J Kwak, Fernanda P Silveira, Joseph M Pilewski, Maria M Crespo, Christian Bermudez, Jay K Bhama, Cornelius J Clancy,

Voriconazole prophylaxis is common following lung transplantation, but the value of therapeutic drug monitoring is unknown. A prospective, observational study of lung transplant recipients (n = 93) receiving voriconazole prophylaxis was performed. Serum voriconazole troughs (n = 331) were measured by high-pressure liquid chromatography. The median initial and subsequent troughs ... Read more >>

Antimicrob. Agents Chemother. (Antimicrobial agents and chemotherapy)
[2012, 56(5):2371-2377]

Cited: 51 times

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Preoperative plasma club (clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation.

R J Shah, N Wickersham, D J Lederer, S M Palmer, E Cantu, J M Diamond, S M Kawut, V N Lama, S Bhorade, M Crespo, E Demissie, J Sonett, K Wille, J Orens, A Weinacker, P Shah, S Arcasoy, D S Wilkes, J D Christie, L B Ware, ,

Inherent recipient factors, including pretransplant diagnosis, obesity and elevated pulmonary pressures, are established primary graft dysfunction (PGD) risks. We evaluated the relationship between preoperative lung injury biomarkers and PGD to gain further mechanistic insight in recipients. We performed a prospective cohort study of recipients in the Lung Transplant Outcomes Group ... Read more >>

Am. J. Transplant. (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons)
[2014, 14(2):446-452]

Cited: 5 times

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Integration and Evaluation of Clinical Decision Support Systems for Diagnosis Idopathics Pulmonary Fibrosis (IPF).

Yunhee Lee, Youngmoon Chae, Sungwan Jeon,

OBJECTIVES: The purpose of this study was to develop clinical decision support systems (CDSS) that are integrated with hospital information systems for the differential diagnosis of idiopathic pulmonary fibrosis (IPF). METHODS: The integrated CDSS were validated and evaluated by physicians. Knowledge modeling for diagnosing IPF was performed by knowledge working ... Read more >>

Healthc Inform Res (Healthcare informatics research)
[2010, 16(4):260-272]

Cited: 1 time

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International Classification of Diseases coding changes lead to profound declines in reported idiopathic pulmonary arterial hypertension mortality and hospitalizations: implications for database studies.

Jeffrey Link, Craig Glazer, Fernando Torres, Kelly Chin,

Database studies have reported several associations between the diagnosis of idiopathic pulmonary arterial hypertension (IPAH) and mortality attributable to IPAH, including older age, black race, and diabetes.We investigated reported deaths and hospital discharges coded as IPAH and compared these with other forms of pulmonary hypertension. Three databases were used: the ... Read more >>

Chest (Chest)
[2011, 139(3):497-504]

Cited: 18 times

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Classification and natural history of the idiopathic interstitial pneumonias.

Dong Soon Kim, Harold R Collard, Talmadge E King,

In the American Thoracic Society/European Respiratory Society consensus classification, idiopathic interstitial pneumonias are classified into seven clinicopathologic entities. The classification is largely based on histopathology, but depends on the close interaction of clinician, radiologist, and pathologist. An accurate diagnosis can be very difficult, especially when deciding between idiopathic pulmonary fibrosis ... Read more >>

Proc Am Thorac Soc (Proceedings of the American Thoracic Society)
[2006, 3(4):285-292]

Cited: 177 times

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