Full Text Journal Articles about
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Neuronal expression of Ca2+ oscillation initiator is linked to rapid neonatal growth in mice.

Woojin Kang, Kenji Yamatoya, Kenji Miyado, Mami Miyado, Yoshitaka Miyamoto,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 0 times

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Caspar SUMOylation regulates Drosophila lifespan.

Bhagyashree Kaduskar, Deepti Trivedi, Girish S Ratnaparkhi,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 0 times

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The autophagy gene product BEC-1 supports normal aging and neurodevelopment in Caenorhabditis elegans: Integration.

Nicholas Ashley, Andrea Holgado,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

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Presumptive heterophil extracellular traps recognized cytologically in nine reptile patients with inflammatory conditions.

A J Flanders, R J Ossiboff, J F X Wellehan, A B Alexander, D V E Fredholm, T M Desiderio, N I Stacy,

<h4>Background</h4>Neutrophil extracellular traps (NETs) represent a novel cellular mechanism of antimicrobial defense activity. Intravascular neutrophils produce extracellular web-like structures composed of chromatin, histones, and cytoplasmic granule proteins to attack and kill microbes. They may impact both pathogen and host; NETs correlate strongly with disseminated intravascular coagulation and mortality in critically ... Read more >>

Vet Q (The veterinary quarterly)
[2021, 41(1):89-96]

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Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases.

Mary E Marquart,

Bacterial proteases and peptidases are integral to cell physiology and stability, and their necessity in <i>Streptococcus pneumoniae</i> is no exception. Protein cleavage and processing mechanisms within the bacterial cell serve to ensure that the cell lives and functions in its commensal habitat and can respond to new environments presenting stressful ... Read more >>

Virulence (Virulence)
[2021, 12(1):766-787]

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Protective effects of Re-yan-ning mixture on Streptococcus pneumonia in rats based on network pharmacology.

Lizhu Han, Jing Kou, Kunxia Hu, Yunlan Wang, Zhishu Tang, Zhisheng Wu, Xiao Song,

<h4>Context</h4>Re-yan-ning mixture (RYNM) is a new national drug approved by China's State Food and Drug Administration for the treatment of colds, simple pneumonia and acute bronchitis.<h4>Objective</h4>To determine the mechanism of action of RYNM in the treatment of bacterial pneumonia.<h4>Materials and methods</h4>Using the network pharmacology approach, the multiple components, component candidate ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2021, 59(1):209-221]

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Infections in hematopoietic stem cell transplant patients admitted to Hematology intensive care unit: a single-center study.

Tuğba Barlas, Kamil İnci, Gulbin Aygencel, Melda Türkoğlu, Özlem Güzel Tunçcan, Ferda Can, Lale Aydın Kaynar, Zübeyde Nur Özkurt, Zeynep Arzu Yeğin, Münci Yağcı,

<h4>Objective</h4>The aim of this study was to investigate the data of HSCT patients who were admitted to our Hematology ICU due to infections or infectious complications.<h4>Materials and methods</h4>HSCT patients who were admitted to our Hematology ICU between 01 January 2014 and 01 September 2017 were analyzed retrospectively.<h4>Results</h4>62 HSCT patients were ... Read more >>

Hematology (Hematology (Amsterdam, Netherlands))
[2021, 26(1):328-339]

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Clinical descriptive analysis of severe Pneumocystis jirovecii pneumonia in renal transplantation recipients.

Dan Xie, Wen Xu, Jingya You, Xiaofeng Yuan, Mingliang Li, Xiaogang Bi, Kouxing Zhang, Heng Li, Ying Xian,

<i>Pneumocystis jirovecii (P. jirovecii)</i> pneumonia (PJP) is an opportunistic fungal infection after renal transplantation, which is always severe, difficult to diagnose, combined with multiple complications and have poor prognosis. We retrospectively analyzed clinical data, including risk factors, diagnosis, treatment and complications of seven clinical cases suffered with severe PJP after ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1264-1272]

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Effect of a genetically engineered interferon-alpha versus traditional interferon-alpha in the treatment of moderate-to-severe COVID-19: a randomised clinical trial.

Chuan Li, Fengming Luo, Chengwu Liu, Nian Xiong, Zhihua Xu, Wei Zhang, Ming Yang, Ye Wang, Dan Liu, Chao Yu, Jia Zeng, Li Zhang, Duo Li, Yanbin Liu, Mei Feng, Ruoyang Liu, Jiandong Mei, Senyi Deng, Zhen Zeng, Yuanhong He, Haiyan Liu, Zhengyu Shi, Meng Duan, Deying Kang, Jiayu Liao, Weimin Li, Lunxu Liu,

<h4>Background</h4>There are few effective therapies for coronavirus disease 2019 (COVID-19) upon the outbreak of the pandemic. To compare the effectiveness of a novel genetically engineered recombinant super-compound interferon (rSIFN-co) with traditional interferon-alpha added to baseline antiviral agents (lopinavir-ritonavir or umifenovir) for the treatment of moderate-to-severe COVID-19.<h4>Method</h4>In this multicenter randomized (1:1) ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):391-401]

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Bacterial and viral infections and related inflammatory responses in chronic obstructive pulmonary disease.

Silvestro Ennio D'Anna, Mauro Maniscalco, Francesco Cappello, Mauro Carone, Andrea Motta, Bruno Balbi, Fabio L M Ricciardolo, Gaetano Caramori, Antonino Di Stefano,

In chronic obstructive pulmonary disease (COPD) patients, bacterial and viral infections play a relevant role in worsening lung function and, therefore, favour disease progression. The inflammatory response to lung infections may become a specific indication of the bacterial and viral infections. We here review data on the bacterial-viral infections and ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):135-150]

Cited: 1 time

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Relation between insulin growth factor 1 and survival after SARS-CoV-2(COVID 19) infection in elderly kidney transplant recipients.

Amin Roshdy Soliman, Khaled Marzouk Sadek,

Ren Fail (Renal failure)
[2021, 43(1):388-390]

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Swertiamarin supplementation prevents obesity-related chronic inflammation and insulin resistance in mice fed a high-fat diet.

Liang Xu, Dandan Li, Yuqin Zhu, Suili Cai, Xue Liang, Ying Tang, Shengnan Jin, Chunming Ding,

Obesity is characterized by low-grade chronic inflammation, which underlies insulin resistance and non-alcoholic fatty liver disease (NAFLD). Swertiamarin is a secoiridoid glycoside that has been reported to ameliorate diabetes and NAFLD in animal models. However, the effects of swertiamarin on obesity-related inflammation and insulin resistance have not been fully elucidated. ... Read more >>

Adipocyte (Adipocyte)
[2021, 10(1):160-173]

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Spontaneous ilio-psoas haematomas (IPHs): a warning for COVID-19 inpatients.

Alessandra Vergori, Elisa Pianura, Patrizia Lorenzini, Alessandra D'Abramo, Federica Di Stefano, Susanna Grisetti, Serena Vita, Carmela Pinnetti, Davide Roberto Donno, Maria Cristina Marini, Emanuele Nicastri, Stefania Ianniello, Andrea Antinori, ,

<h4>Introduction</h4>Critically ill patients with COVID-19 are at increased risk of developing a hypercoagulable state due to haemostatic changes directly related to the SARS-CoV-2 infection or to the consequence of the cytokine storm. Anticoagulation is now recommended to reduce the thrombotic risk. Ilio-psoas haematoma (IPH) is a potentially lethal condition that ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):295-301]

Cited: 3 times

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Differences between recorded diagnoses of patients of an emergency department and office-hours primary care doctors: a register-based study in a Finnish town.

Mika Lehto, Katri Mustonen, Marko Raina, Timo Kauppila,

To determine the extent to which it is possible to provide continuity of primary care for those who visit Emergency Departments (EDs) we studied how recorded diagnoses in primary care differ, depending on whether the patient is met in an ED or a primary care office-hours practice. In the present, ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1935593]

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Time-course analysis reveals that corticosteroids resuscitate diminished CD8+ T cells in COVID-19: a retrospective cohort study.

Fangzhou Ye, Jing Liu, Liangkai Chen, Bin Zhu, Li Yu, Boyun Liang, Ling Xu, Sumeng Li, Sihong Lu, Lei Fan, Dongliang Yang, Xin Zheng,

<h4>Objective</h4>To illustrate the effect of corticosteroids and heparin, respectively, on coronavirus disease 2019 (COVID-19) patients' CD8+ T cells and D-dimer.<h4>Methods</h4>In this retrospective cohort study involving 866 participants diagnosed with COVID-19, patients were grouped by severity. Generalized additive models were established to explore the time-course association of representative parameters of coagulation, ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):181-188]

Cited: 2 times

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Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against renal ischemia/reperfusion injury by inhibiting inflammation.

A-Feng Miao, Jian-Xiang Liang, Lei Yao, Jun-Ling Han, Li-Juan Zhou,

Hypoxia-induced inflammation is the critical pathological feature of acute kidney injury (AKI). Activation of hypoxia-inducible factor (HIF) signaling is considered as a central mechanism of body adapting to hypoxia. Hypoxia-inducible factor prolyl hydroxylase inhibitor FG-4592 (Roxadustat) is a first-in-class HIF stabilizer for the treatment of patients with renal anemia. The ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):803-810]

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The role and research progress of the balance and interaction between regulatory T cells and other immune cells in obesity with insulin resistance.

Leiling Liu, Jiahui Hu, Yating Wang, Hao Lei, Danyan Xu,

Metabolic homoeostasis in adipose tissue plays a major role in obesity-related insulin resistance (IR). Regulatory T (Treg) cells have been recorded to regulate metabolic homoeostasis in adipose tissue. However, their specific mechanism is not yet known. This review aims to present the role of Treg cells and other immune cells ... Read more >>

Adipocyte (Adipocyte)
[2021, 10(1):66-79]

Cited: 1 time

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Ac2-26 mitigated acute respiratory distress syndrome rats via formyl peptide receptor pathway.

Yingnan Ju, Lin Qiu, Xikun Sun, Hengyu Liu, Wei Gao,

<h4>Background</h4>Acute respiratory distress syndrome (ARDS) is characterized by severe local and systemic inflammation. Ac2-26, an Annexin A1 Peptide, can reduce the lung injury induced by reperfusion via the inhibition of inflammation. The present study aims to evaluate the effect and mechanism of Ac2-26 in ARDS.<h4>Methods</h4>Thirty-two rats were anaesthetized and randomized ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):653-661]

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First Nations' hospital readmission ending in death: a potential sentinel indicator of inequity?

Josée Lavoie, Wanda Phillips-Beck, Kathi Avery Kinew, Grace Kyoon-Achan, Alan Katz,

In this study, we focused on readmissions for Ambulatory Care Sensitive Conditions (ACSC) ending in death, to capture those admissions and readmissions that might have been prevented if responsive primary healthcare was accessible. We propose this as a sentinel indicator of equity. We conducted analyses of Manitoba-based 30-day hospital readmission ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1859824]

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Chest CT features associated with the clinical characteristics of patients with COVID-19 pneumonia.

Ruichao Niu, Shuming Ye, Yongfeng Li, Hua Ma, Xiaoting Xie, Shilian Hu, Xiaoming Huang, Yangshu Ou, Jie Chen,

<h4>Objectives</h4>Coronavirus disease 2019 (COVID-19) has rapidly swept across the world. This study aimed to explore the relationship between the chest CT findings and clinical characteristics of COVID-19 patients.<h4>Methods</h4>Patients with COVID-19 confirmed by next-generation sequencing or RT-PCR who had undergone more than 4 serial chest CT procedures were retrospectively enrolled.<h4>Results</h4>This study ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):169-180]

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Microwave assisted green synthesis of silver nanoparticles for optical, catalytic, biological and electrochemical applications.

V N Anjana, Majo Joseph, Sijo Francis, Alex Joseph, Ebey P Koshy, Beena Mathew,

Plant-derived nanoparticles have multi-functionalities owing to their ecological origin and biocompatible nature. A novel and stable silver nanoparticle (AgNP) was reported here using <i>Cyanthillium cinereum</i> (<i>C. cinereum</i>) as a reducing as well as capping agent by rapid microwave-assisted green method. The synthesized nanoparticles revealed their crystalline and spherical nature with ... Read more >>

Artif Cells Nanomed Biotechnol (Artificial cells, nanomedicine, and biotechnology)
[2021, 49(1):438-449]

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Characterization of an NDM-5-producing hypervirulent Klebsiella pneumoniae sequence type 65 clone from a lung transplant recipient.

Jiankang Zhao, Yulin Zhang, Yanyan Fan, Jiajing Han, Zhujia Xiong, Xinmeng Liu, Binbin Li, Binghuai Lu, Bin Cao,

The emergence of New Delhi Metallo-β-lactamase (NDM)-producing <i>Klebsiella pneumoniae</i> has aroused critical concern worldwide. Herein, we reported the first emergence of NDM-5-producing <i>K. pneumoniae</i> isolates in a 68-year-old lung transplant recipient, who died of septic shock 13 days after surgery. The <i>K. pneumoniae</i> strain KP22937 isolated from the bloodstream of ... Read more >>

Emerg Microbes Infect (Emerging microbes & infections)
[2021, 10(1):396-399]

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Incidence of invasive Group B Streptococcus (iGBS) infections and the factors associated with iGBS mortality in adults during 2013-2017: a retrospective study at Thailand's largest national tertiary referral center.

Pakpoom Phoompoung, Nantaporn Pirogard, Amornrut Leelaporn, Nasikarn Angkasekwinai,

<h4>Objectives</h4>To determine the incidence of invasive Group B streptococcal (iGBS) diseases and the factors significantly associated with iGBS mortality in adult patients.<h4>Material and methods</h4>This retrospective study included adults with a positive culture for GBS isolated from a sterile site at Siriraj Hospital - Thailand's largest tertiary care hospital - during ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):715-721]

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Performance of prediction models for short-term outcome in COVID-19 patients in the emergency department: a retrospective study.

Paul M E L van Dam, Noortje Zelis, Sander M J van Kuijk, Aimée E M J H Linkens, Renée A G Brüggemann, Bart Spaetgens, Iwan C C van der Horst, Patricia M Stassen,

<h4>Introduction</h4>Coronavirus disease 2019 (COVID-19) has a high burden on the healthcare system. Prediction models may assist in triaging patients. We aimed to assess the value of several prediction models in COVID-19 patients in the emergency department (ED).<h4>Methods</h4>In this retrospective study, ED patients with COVID-19 were included. Prediction models were selected ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):402-409]

Cited: 1 time

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Acute otitis media and pneumococcal vaccination - an observational cross-sectional study of otitis media among vaccinated and unvaccinated children in Greenland.

Simon Imer Jespersen, Malene Nøhr Demant, Michael Lynge Pedersen, Preben Homøe,

<i>Streptococcus pneumoniae</i> is one of the main pathogens leading to otitis media. In 2010, the 13-valent pneumococcal conjugate vaccine (PCV13) was implemented in the Greenlandic childhood vaccination programme, but the effect of this change is not yet well documented. The objective of this study is to evaluate the effect of ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2021, 80(1):1858615]

Cited: 0 times

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