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Neuronal expression of Ca2+ oscillation initiator is linked to rapid neonatal growth in mice.

Woojin Kang, Kenji Yamatoya, Kenji Miyado, Mami Miyado, Yoshitaka Miyamoto,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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The autophagy gene product BEC-1 supports normal aging and neurodevelopment in Caenorhabditis elegans: Integration.

Nicholas Ashley, Andrea Holgado,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

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Caspar SUMOylation regulates Drosophila lifespan.

Bhagyashree Kaduskar, Deepti Trivedi, Girish S Ratnaparkhi,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Hydrogen-rich bath with nano-sized bubbles improves antioxidant capacity based on oxygen radical absorbing and inflammation levels in human serum.

Yoshiharu Tanaka, Li Xiao, Nobuhiko Miwa,

This study compared the effects of hydrogen-water (HW) bath on the oxygen radical absorption-based antioxidant capacity and the inflammatory indicator, C-reactive protein (CRP), in serum between healthy volunteers and inflammatory/collagen disease-patients. The HW bath apparatus supplied nano-bubbles with a diameter of 110 ± 10 nm and 338-682 μg/L of dissolved ... Read more >>

Med Gas Res (Medical gas research)
[2022, 12(3):91-99]

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Lithium promotes recovery after spinal cord injury.

Ying-Jie Zhao, Hao Qiao, Dong-Fan Liu, Jie Li, Jia-Xi Li, Su-E Chang, Teng Lu, Feng-Tao Li, Dong Wang, Hao-Peng Li, Xi-Jing He, Fang Wang,

Lithium is associated with oxidative stress and apoptosis, but the mechanism by which lithium protects against spinal cord injury remains poorly understood. In this study, we found that intraperitoneal administration of lithium chloride (LiCl) in a rat model of spinal cord injury alleviated pathological spinal cord injury and inhibited expression ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(6):1324-1333]

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Perioperative melatonin in COVID-19 patients: benefits beyond sedation and analgesia.

Abhijit S Nair,

Cytokine storm in coronavirus disease 2019 (COVID-19) patients leads to acute lung injury, acute respiratory distress syndrome, multiorgan dysfunction, shock, and thrombosis thus contributing to significant morbidity and mortality. Several agents like steroids, ascorbic acid, vitamins (C, D, E), glutathione, N-acetylcysteine have been used and several studies are underway to ... Read more >>

Med Gas Res (Medical gas research)
[2022, 12(2):41-43]

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Ozone gas applied through nebulization as adjuvant treatment for lung respiratory diseases due to COVID-19 infections: a prospective randomized trial.

Erhan Dengiz, Çağrı Özcan, Yusuf İzzettin Güven, Selcen Uçar, Behçet Kemal Ener, Semih Sözen, Buket Yağcı, İnal Albek Güzel, Betül Yiğit, Aslınur Andaç, Beyza Güneş, Emire Bor, Uğur Karabudak, Ali Kaya,

The objective of this study was to provide lung disinfection by nebulizing ozone gas with distilled water and olive oil for patients who have clinical symptoms due to coronavirus disease 2019 (COVID-19). The study attempted to reduce the viral load of COVID-19 in the lungs of patients, to provide a ... Read more >>

Med Gas Res (Medical gas research)
[2022, 12(2):55-59]

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Increased activation of the caudate nucleus and parahippocampal gyrus in Parkinson's disease patients with dysphagia after repetitive transcranial magnetic stimulation: a case-control study.

Pei-Ling Huang, Song-Jian Wang, Rui-Feng Sun, Zi-Man Zhu, Xiao-Ling Li, Wen-Shan Li, Meng-Yue Wang, Meng Lin, Wei-Jun Gong,

Repetitive transcranial magnetic stimulation (rTMS) has been shown to effectively improve impaired swallowing in Parkinson's disease (PD) patients with dysphagia. However, little is known about how rTMS affects the corresponding brain regions in this patient group. In this case-control study, we examined data from 38 PD patients with dysphagia who ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(5):1051-1058]

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Prediction of diagnosis and prognosis of COVID-19 disease by blood gas parameters using decision trees machine learning model: a retrospective observational study.

Mehmet Tahir Huyut, Hilal Üstündağ,

The coronavirus disease 2019 (COVID-19) epidemic went down in history as a pandemic caused by corona-viruses that emerged in 2019 and spread rapidly around the world. The different symptoms of COVID-19 made it difficult to understand which variables were more influential on the diagnosis, course and mortality of the disease. ... Read more >>

Med Gas Res (Medical gas research)
[2022, 12(2):60-66]

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Can united airway disease be the cause of variable severity experience of COVID-19 in health care workers?

Merih Onal, Ozkan Onal, Alparslan Turan,

Med Gas Res (Medical gas research)
[2022, 12(2):69-71]

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Effect of vocal respiratory training on respiratory function and respiratory neural plasticity in patients with cervical spinal cord injury: a randomized controlled trial.

Xiao-Ying Zhang, Wei-Yong Yu, Wen-Jia Teng, Yi-Chuan Song, De-Gang Yang, Hong-Wei Liu, Song-Huai Liu, Xiao-Bing Li, Wen-Zhu Wang, Jian-Jun Li,

In previous studies, researchers have used singing to treat respiratory function in patients with spinal cord injury. However, few studies have examined the way in which vocal training affects respiratory neural plasticity in patients with spinal cord injury. Vocal respiratory training (VRT) is a type of vocal muscle-related treatment that ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(5):1065-1071]

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HOTTIP downregulation reduces neuronal damage and microglial activation in Parkinson's disease cell and mouse models.

Peng Lun, Tao Ji, De-Hong Wan, Xia Liu, Xiao-Dong Chen, Shuai Yu, Peng Sun,

HOXA transcript at the distal tip (HOTTIP), a newly identified long noncoding RNA, has been shown to exhibit anti-inflammatory effects and inhibit oxygen-glucose deprivation-induced neuronal apoptosis. However, its role in Parkinson's disease (PD) remains unclear. 1-Methyl-4-phenylpyridium (MPP<sup>+</sup>) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used to establish PD models in SH-SY5Y and BV2 ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):887-897]

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Therapeutic potential of translocator protein ligands for age-related macular degeneration.

Xing Li, Zhiming He, Xinhua Shu,

Neural Regen Res (Neural regeneration research)
[2022, 17(4):793-794]

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Diagnosis of Balamuthia mandrillaris Encephalitis by Thymine-Adenine Cloning Using Universal Eukaryotic Primers.

Ju Yeong Kim, Myung-Hee Yi, Myungjun Kim, Joon-Sup Yeom, Hyun Dong Yoo, Seong Min Kim, Tai-Soon Yong,

<h4>Background</h4>Identifying the causal pathogen of encephalitis remains a clinical challenge. A 50-year-old man without a history of neurological disease was referred to our department for the evaluation of an intracranial lesion observed on brain magnetic resonance imaging (MRI) scans, and the pathology results suggested protozoal infection. We identified the species ... Read more >>

Ann Lab Med (Annals of laboratory medicine)
[2022, 42(2):196-202]

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Neuroprotective effects of long noncoding RNAs involved in ischemic postconditioning after ischemic stroke.

Wei Ma, Chun-Yan Li, Si-Jia Zhang, Cheng-Hao Zang, Jin-Wei Yang, Zhen Wu, Guo-Dong Wang, Jie Liu, Wei Liu, Kuang-Pin Liu, Yu Liang, Xing-Kui Zhang, Jun-Jun Li, Jian-Hui Guo, Li-Yan Li,

During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in rats remains unclear. In this study, RNA isolation and library preparation was performed for long ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(6):1299-1309]

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M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury.

Shui-Sheng Yu, Zi-Yu Li, Xin-Zhong Xu, Fei Yao, Yang Luo, Yan-Chang Liu, Li Cheng, Mei-Ge Zheng, Jue-Hua Jing,

After spinal cord injury (SCI), astrocytes gradually migrate to and surround the lesion, depositing chondroitin sulfate proteoglycan-rich extracellular matrix and forming astrocytic scar, which limits the spread of inflammation but hinders axon regeneration. Meanwhile, microglia gradually accumulate at the lesion border to form microglial scar and can polarize to generate ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(5):1072-1079]

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Autoimmune Meningitis and Encephalitis.

Megan B Richie,

Meningitis and encephalitis are inflammatory syndromes of the meninges and brain parenchyma, respectively, and may be identified either by finding definitive evidence of inflammation on tissue pathology or by cerebrocpinal fluid (CSF) analysis showing pleocytosis or intrathecal antibody synthesis. Clinicians evaluating undifferentiated meningitis or encephalitis should simultaneously consider autoimmune, infectious, ... Read more >>

Neurol Clin (Neurologic clinics)
[2022, 40(1):93-112]

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SARS-CoV-2 involvement in central nervous system tissue damage.

Muhammad Ali Haidar, Zaynab Shakkour, Mohammad Amine Reslan, Nadine Al-Haj, Perla Chamoun, Karl Habashy, Hasan Kaafarani, Shima Shahjouei, Sarah H Farran, Abdullah Shaito, Esber S Saba, Bassam Badran, Mirna Sabra, Firas Kobeissy, Maya Bizri,

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread globally, it became evident that the SARS-CoV-2 virus infects multiple organs including the brain. Several clinical studies revealed that patients with COVID-19 infection experience an array of neurological signs ranging in severity from headaches to life-threatening strokes. Although ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(6):1228-1239]

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Celeboxib-mediated neuroprotection in focal cerebral ischemia: an interplay between unfolded protein response and inflammation.

María Santos-Galdiano, Diego Pérez-Rodríguez, Arsenio Fernández-López,

Neural Regen Res (Neural regeneration research)
[2022, 17(2):302-303]

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Infectious Meningitis and Encephalitis.

Rachel J Bystritsky, Felicia C Chow,

Infectious meningitis and encephalitis are associated with significant morbidity and mortality worldwide. Acute bacterial meningitis is rapidly fatal and early recognition and institution of therapy are imperative. Viral meningitis is typically a benign self-limited illness. Chronic meningitis (defined as presenting with >4 weeks of symptoms) is most often caused by tuberculosis and ... Read more >>

Neurol Clin (Neurologic clinics)
[2022, 40(1):77-91]

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Approach to Myelopathy and Myelitis.

Anne G Douglas, Denise J Xu, Maulik P Shah,

Myelopathy can present acutely or more insidiously and has a broad differential diagnosis. In addition to the clinical history and neurologic examination, diagnostic testing, including MRI and cerebrospinal fluid analysis, as well as thorough review of patient comorbidities, risk factors, and potential toxic exposures, can help neurohospitalists distinguish between various ... Read more >>

Neurol Clin (Neurologic clinics)
[2022, 40(1):133-156]

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Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity.

Federica Ferrari, Antonio Moretti, Roberto Federico Villa,

Diabetes mellitus and associated chronic hyperglycemia enhance the risk of acute ischemic stroke and lead to worsened clinical outcome and increased mortality. However, post-stroke hyperglycemia is also present in a number of non-diabetic patients after acute ischemic stroke, presumably as a stress response. The aim of this review is to ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(2):292-299]

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The mechanism behind activation of the Nod-like receptor family protein 3 inflammasome in Parkinson's disease.

Jing Wang, Xiao-Na Zhang, Jin-Ni Fang, Fei-Fei Hua, Jing-Yang Han, Zeng-Qiang Yuan, An-Mu Xie,

Previous studies have shown that the ATP-P2X4 receptor signaling pathway mediates the activation of the Nod-like receptor family protein 3 (NLRP3) inflammasome. The NLRP3 inflammasome may promote renal interstitial inflammation in diabetic nephropathy. As inflammation also plays an important role in the pathogenesis of Parkinson's disease, we hypothesized that the ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):898-904]

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Delving into the recent advancements of spinal cord injury treatment: a review of recent progress.

Joseph A Flack, Krishna Deo Sharma, Jennifer Yanhua Xie,

Spinal cord injury (SCI) research is a very complex field lending to why reviews of SCI literatures can be beneficial to current and future researchers. This review focuses on recent articles regarding potential modalities for the treatment and management of SCI. The modalities were broken down into four categories: neuroprotection-pharmacologic, ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(2):283-291]

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Imaging of Complications of Chemoradiation.

Prashant Raghavan, Matthew E Witek, Robert E Morales,

Chemoradiation for head and neck cancer is associated with a variety of early and late complications. Toxicities may affect the aero-digestive tract (mucositis, salivary gland injury), regional osseous and cartilaginous structures (osteoradionecrosis (ORN) and chondronecrosis), vasculature (progressive radiation vasculopathy and carotid blow out syndromes), and neural structures (optic neuritis, myelitis, ... Read more >>

Neuroimaging Clin N Am (Neuroimaging clinics of North America)
[2022, 32(1):93-109]

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