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Infant of Diabetic Mother

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The lived experiences of healthcare during pregnancy, birth, and three months after in women with type 1 diabetes mellitus.

Helena Dahlberg, Marie Berg,

Being pregnant, giving birth, and becoming a mother the first months after birth, is for women with type 1 diabetes mellitus (T1DM) a period of difficult challenges. In order to identify their need of support from healthcare, the aim of this study was to describe healthcare during pregnancy, labour, birth, ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2020, 15(1):1698496]

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Glycemic control and fetal growth of women with diabetes mellitus and subsequent hypertensive disorders of pregnancy.

Mamoru Morikawa, Emi Kato-Hirayama, Michinori Mayama, Yoshihiro Saito, Kinuko Nakagawa, Takeshi Umazume, Kentaro Chiba, Satoshi Kawaguchi, Kazuhiko Okuyama, Hidemichi Watari,

Pregnant women with diabetes mellitus (DM) are at high risk for hypertensive disorder of pregnancy (HDP). Women with poor control DM sometimes have heavy-for-dates infants. However, women with HDP sometimes have light-for-dates infants. We aim to clarify the relationship between glycemic control and fetal growth in women with DM and/or ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0230488]

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Maternal diabetes and obesity influence the fetal epigenome in a largely Hispanic population.

Heather E Rizzo, Elia N Escaname, Nicholas B Alana, Elizabeth Lavender, Jonathan Gelfond, Roman Fernandez, Matthew A Hibbs, Jonathan M King, Nicholas R Carr, Cynthia L Blanco,

BACKGROUND:Obesity and diabetes mellitus are directly implicated in many adverse health consequences in adults as well as in the offspring of obese and diabetic mothers. Hispanic Americans are particularly at risk for obesity, diabetes, and end-stage renal disease. Maternal obesity and/or diabetes through prenatal programming may alter the fetal epigenome ... Read more >>

Clin Epigenetics (Clinical epigenetics)
[2020, 12(1):34]

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Language, Motor, and Cognitive Outcomes of Toddlers Who Were Born Preterm.

Diane Frome Loeb, Caitlin M Imgrund, Jaehoon Lee, Steven M Barlow,

Purpose The purpose of this study was to examine the language, motor, and cognitive abilities of children born preterm in four categories: (a) healthy preterm infants, (b) infants of diabetic mothers, (c) infants with respiratory distress syndrome, and (d) infants with chronic lung disease when the children were 30 months, ... Read more >>

Am J Speech Lang Pathol (American journal of speech-language pathology)
[2020, :1-13]

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Urine-derived stem cells for the therapy of diabetic nephropathy mouse model.

G Xiong, L Tao, W-J Ma, M-J Gong, L Zhao, L-J Shen, C-L Long, D-Y Zhang, Y-Y Zhang, G-H Wei,

OBJECTIVE:Diabetic nephropathy (DN) is one of the most representative diabetic microangiopathy complications. So far, there have been no satisfactory therapeutic strategies, and the injection of stem cells provides a target for DN therapy. PATIENTS AND METHODS:Urine-derived stem cells (USCs) were obtained from 9 healthy men. 24 mice were randomly and ... Read more >>

Eur Rev Med Pharmacol Sci (European review for medical and pharmacological sciences)
[2020, 24(3):1316-1324]

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Patterns of antenatal corticosteroid administration in a cohort of women with diabetes in pregnancy.

Jeremy F Tuohy, Frank H Bloomfield, Jane E Harding, Caroline A Crowther,

Antenatal corticosteroids administered to the mother prior to birth decrease the risk of mortality and major morbidity in infants born at less than 35 weeks' gestation. However, the evidence relating to women with diabetes in pregnancy is limited. Clinical guidelines for antenatal corticosteroid administration recommend that women with diabetes in ... Read more >>

PLoS ONE (PloS one)
[2020, 15(2):e0229014]

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Eosinophilic pancreatitis: a rare or unexplored disease entity?

Murli Manohar, Alok K Verma, Gulshan Singh, Anil Mishra,

Several case reports show accumulation of eosinophils in pancreatitis patients and term the disease as "eosinophilic pancreatitis (EP)". EP usually presents with a pancreatic tumour and abdominal pain in obstructive jaundice, which is generally not diagnosed until the patient undergoes pancreatic resection. Histologically, EP reveals distinct patterns like diffused, periductal, ... Read more >>

Prz Gastroenterol (Przeglad gastroenterologiczny)
[2020, 15(1):34-38]

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Association between Bioactive Molecules in Breast Milk and Type 1 Diabetes Mellitus.

Tajudeen Yahaya, Ufuoma Shemishere,

The association between breastfeeding and type 1 diabetes mellitus (T1DM) is controversial. However, several recent studies have established a link between these two factors, necessitating a need to review this subject to raise public awareness. Current research indicates that breast milk contains a variety of bioactive substances including immunoglobulins, oligosaccharides, ... Read more >>

Sultan Qaboos Univ Med J (Sultan Qaboos University medical journal)
[2020, 20(1):e5-e12]

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Hearing outcomes in children of diabetic pregnancies.

Joshua A Lee, Charmee H Mehta, Shaun A Nguyen, Ted A Meyer,

OBJECTIVE:Children of diabetic pregnancies (CDPs) face numerous risk factors for hearing loss (HL). The objective of this study was to investigate the hearing outcomes of CDPs on a population scale. METHODS:Using the Audiological and Genetic Database, the prevalence, severity, and progression of HL in CDPs was compared against children of ... Read more >>

Int. J. Pediatr. Otorhinolaryngol. (International journal of pediatric otorhinolaryngology)
[2020, 132:109925]

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Non classic presentations of a genetic mutation typically associated with transient neonatal diabetes.

Janani Devaraja, Charlotte Elder, Adrian Scott,

Summary:This case report describes a family pedigree of a mother and her children with an E227K mutation in the KCNJ11 gene. People with this particular gene mutation typically present with transient neonatal diabetes; with more than half the cohort relapsing into permanent diabetes in adolescence or early adulthood. However, the ... Read more >>

Endocrinol Diabetes Metab Case Rep (Endocrinology, diabetes & metabolism case reports)
[2020, 2020:]

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Use of the modified myocardial performance index for evaluating fetal cardiac functions in pregestational diabetic pregnancy babies.

Merve Oncel Alanyali, Fatos Alkan, Burcu Artunc Ulkumen, Senol Coskun,

The aim of this study is assessment of importance of use of the modified myocardial performance index (Mod-MPI) for the evaluation of foetal cardiac function in foetuses of women with pregestational diabetes mellitus (PDM). In this study, data of 30 pregnant patients aged 18-45 years diagnosed with PDM and 30 pregnant ... Read more >>

J Obstet Gynaecol (Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology)
[2020, :1-6]

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Etiology and therapeutic management of neonatal jaundice in Iran: a systematic review and meta-analysis.

Yadollah Zahed Pasha, Shaghayegh Alizadeh-Tabari, Ermia Zahed Pasha, Mohammad Zamani,

BACKGROUND:Jaundice is a life-threatening disorder in the neonates. In the present study, we aimed to assess systematically available evidence on causes and management of jaundice in Iranian newborn patients. METHODS:We searched the databases of PubMed, Web of Sciences, Scopus and Google Scholar for English articles published since inception until May ... Read more >>

World J Pediatr (World Journal of Pediatrics)
[2020, :]

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Socioeconomic and racial disparities in the prevalence of congenital heart disease in infants of diabetic mothers.

Fu-Sheng Chou, Rikesh Chakradhar, Laxmi V Ghimire,

Infants of diabetic mothers (IDM) are at increased risk for congenital heart disease (CHD). There is little information in the literature about the impact of economic status and race/ethnicity on the prevalence of CHD in IDM. Using the KID national database collected from 2003 to 2012, we studied over 180,000 ... Read more >>

J. Matern. Fetal. Neonatal. Med. (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians)
[2019, :1-4]

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A preview of selected articles.

Stuart P Atkinson,

Stem Cells Transl Med (Stem cells translational medicine)
[2020, 9(3):285-288]

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"INTERGROWTH21st vs customized fetal growth curves in the assessment of the neonatal nutritional status: a retrospective cohort study of gestational diabetes".

Juan Jesús Fernández-Alba, Estefanía Soto Pazos, Rocío Moreno Cortés, Ángel Vilar Sánchez, Carmen González Macías, María Castillo Lara, Luis Moreno Corral, José Antonio Sainz Bueno,

BACKGROUND:Gestational diabetes mellitus is associated with increased incidence of adverse perinatal outcomes including newborns large for gestational age, macrosomia, preeclampsia, polyhydramnios, stillbirth, and neonatal morbidity. Thus, fetal growth should be monitored by ultrasound to assess for fetal overnutrition, and thereby, its clinical consequence, macrosomia. However, it is not clear which ... Read more >>

BMC Pregnancy Childbirth (BMC pregnancy and childbirth)
[2020, 20(1):139]

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Neonatal cardiac hypertrophy: the role of hyperinsulinism-a review of literature.

Nina D Paauw, Raymond Stegeman, Monique A M J de Vroede, Jacqueline U M Termote, Matthias W Freund, Johannes M P J Breur,

Hypertrophic cardiomyopathy (HCM) in neonates is a rare and heterogeneous disorder which is characterized by hypertrophy of heart with histological and functional disruption of the myocardial structure/composition. The prognosis of HCM depends on the underlying diagnosis. In this review, we emphasize the importance to consider hyperinsulinism in the differential diagnosis ... Read more >>

Eur. J. Pediatr. (European journal of pediatrics)
[2020, 179(1):39-50]

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Incidence and Risk Factors for Hypoglycemia During Fetal-to-Neonatal Transition in Premature Infants.

Nikki A Mitchell, Chelsey Grimbly, Elizabeth T Rosolowsky, Megan O'Reilly, Maryna Yaskina, Po-Yin Cheung, Georg M Schmölzer,

Objective: To determine the incidence and risk factors associated with neonatal hypoglycemia in the premature population <33 weeks' gestation. Methods: This was a secondary retrospective analysis from previous infants enrolled in randomized controlled trials. A total of 255 infants <33 weeks' gestation were born during the study period. Eight infants ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:34]

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Current understandings of the pathogenesis of type 1 diabetes: Genetics to environment.

Adebola Matthew Giwa, Rizwan Ahmed, Zahra Omidian, Neha Majety, Kagan Ege Karakus, Sarah M Omer, Thomas Donner, Abdel Rahim A Hamad,

Type 1 diabetes (T1D) is an autoimmune disease that usually strikes early in life, but can affect individuals at almost any age. It is caused by autoreactive T cells that destroy insulin-producing beta cells in the pancreas. Epidemiological studies estimate a prevalence of 1 in 300 children in the United ... Read more >>

World J Diabetes (World journal of diabetes)
[2020, 11(1):13-25]

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Breastfeeding initiation or duration and longitudinal patterns of infections up to 2 years and skin rash and respiratory symptoms up to 8 years in the EDEN mother-child cohort.

Camille Davisse-Paturet, Karine Adel-Patient, Anne Forhan, Sandrine Lioret, Isabella Annesi-Maesano, Barbara Heude, Marie Aline Charles, Blandine de Lauzon-Guillain,

This paper aimed to examine the effect of breastfeeding on longitudinal patterns of common infections up to 2 years and respiratory symptoms up to 8 years. To assess the incidence and reoccurrence of infections and allergic symptoms in the first years of life among 1,603 children from the EDEN mother-child ... Read more >>

Matern Child Nutr (Maternal & child nutrition)
[2020, :e12935]

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Infant Death Following Home Birth: A Case Report of Fatal Neonatal Hypoglycemia.

Leah M Schuppener, Robert F Corliss,

Infants born to diabetic mothers are at increased risk for symptomatic hypoglycemia and death after birth. A 36-year-old G4P3 mother with a history of gestational diabetes and newly diagnosed type II insulin-dependent diabetes gave birth at home, in the care of a midwife, to a macrosomic infant girl (10 lbs.). ... Read more >>

J. Forensic Sci. (Journal of forensic sciences)
[2019, :]

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Bioinformatics enrichment analysis of genes and pathways related to maternal type 1 diabetes associated with adverse fetal outcomes.

Ravi Bhushan, Anjali Rani, Akhtar Ali, Vinay Kumar Singh, Pawan K Dubey,

Maternal type 1 diabetes mellitus (T1DM) may affect fetal development by altering the gene expression profile of the umbilical cord. The present study aimed to explore the T1DM-induced gene expression changes in the fetal umbilical cord. The raw gene expression profiles (ID: GSE51546) of umbilical cord tissue obtained from six ... Read more >>

J. Diabetes Complicat. (Journal of diabetes and its complications)
[2020, :107556]

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Infants of Mothers With Diabetes and Subsequent Attention Deficit Hyperactivity Disorder: A Retrospective Cohort Study.

Chien-Heng Lin, Wei-De Lin, I-Ching Chou, Inn-Chi Lee, Syuan-Yu Hong,

Background: Maternal diabetes mellitus (DM) increases the risk of fetal, neonatal, and long-term complications in offspring. Although this has been widely known for decades, data are limited regarding the effect of maternal pregestational and gestational diabetes on the subsequent neurodevelopmental outcome of offspring. This study investigated whether infants of mothers ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:452]

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Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice.

Ran An, Yong Zhang, Yu Qiao, Lili Song, Hongjun Wang, Xiao Dong,

BACKGROUND:Adipose-derived mesenchymal stem cells (ASCs) therapy is emerging as a novel therapeutic option for the treatment of a variety of diseases including diabetes and diabetic wound healing. Multiple studies indicate that ASCs could promote wound healing and reverse diabetes. However, whether ASCs from diabetic donors retain their therapeutic functions and ... Read more >>

Stem Cell Res Ther (Stem cell research & therapy)
[2020, 11(1):120]

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The Initial Oral Microbiota of Neonates Among Subjects With Gestational Diabetes Mellitus.

Zhijiang He, Jiaman Wu, Bin Xiao, Shanqiu Xiao, Hongping Li, Kaifeng Wu,

Objective: The objective was to investigate the potential effect of gestational diabetes mellitus on the initial neonatal oral microbiome community structure. Methods: Oral samples were collected from 20 full-term, vaginally delivered newborns with sterile swabs. Nine of them had mothers diagnosed with gestational diabetes mellitus (GDM group), while 11 had ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2019, 7:513]

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Risk Factors of Respiratory Diseases Among Neonates in Neonatal Intensive Care Unit of Qena University Hospital, Egypt.

Khaled A Abdel Baseer, Mostafa Mohamed, Eman A Abd-Elmawgood,

Background:Respiratory diseases in newborns are considered major causes of neonatal morbidity and mortality especially in developing countries. Its causes are diverse and require early detection and management. This study aimed for detection of the prevalence and risk factors of respiratory diseases in addition to outcome among neonates admitted in neonatal ... Read more >>

Ann Glob Health (Annals of global health)
[2020, 86(1):22]

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