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Hypertensive Encephalopathy

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Pazopanib-induced posterior reversible encephalopathy syndrome with possible syndrome of inappropriate secretion of antidiuretic hormone: an incidental or pathophysiological association?

Jonathan Wong So, Bérenger Largeau, Frédérique Beau-Salinas, Stephan Ehrmann, Christophe Magni, Jérôme Meunier,

Neural Regen Res (Neural regeneration research)
[2020, 15(6):1166-1168]

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Brainstem Posterior Reversible Encephalopathy Syndrome in an Asymptomatic Patient.

Angelo Pascarella, Andrea Quattrone, Umberto Sabatini, Antonio Gambardella, Angelo Labate,

Can J Neurol Sci (The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques)
[2020, 47(2):267-269]

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Posterior Reversible Encephalopathy Syndrome: Pattern on 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Correlated with Magnetic Resonance Imaging in Pediatric Hypertensive Encephalopathy.

Saurabh Arora, Averilicia Passah, Harish Nalli, Harish Goyal, Madhavi Tripathi, Shamim Ahmed Shamim, Chandan Jyoti Das, Rakesh Kumar,

Posterior reversible encephalopathy syndrome (PRES) is characterized clinically by headache, seizures, vomiting, altered mental status, and blurred vision. However, with overlapping and atypical clinical symptoms, PRES becomes a diagnostic challenge. We describe the imaging findings of PRES in magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography-computed tomography in an 11-year-old ... Read more >>

Indian J Nucl Med (Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India)
[2020, 35(1):72-73]

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Plasma levels of matrix metalloproteinase-9 are elevated in individuals with hypertensive crisis.

Flavia Mariana Valente, Days Oliveira de Andrade, Luciana Neves Cosenso-Martin, Cláudia Bernardi Cesarino, Sérgio Mussi Guimarães, Victor Beneditti Guimarães, Riccardo Lacchini, José Eduardo Tanus-Santos, Juan Carlos Yugar-Toledo, José Fernando Vilela-Martin,

BACKGROUND:Matrix metalloproteinase-9 (MMP-9) participates in the degradation of components of the extracellular matrix and it is involved in vascular remodeling and vasomotor changes. The aim of this study was to investigate the plasma levels of MMP-9 in acute vascular alterations due to hypertensive crisis. METHODS:This cross-sectional study was performed in ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):132]

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Clinical, Etiological and Imaging Profile of Posterior Reversible Encephalopathy Syndrome: A Prospective and Follow-Up Study.

Saurabh Bansal, Ramandeep Bansal, Manoj Kumar Goyal, Aastha Takkar, Ramandeep Singh, Paramjeet Singh, Vivek Lal,

Background:Although first described more than two decades ago, posterior reversible encephalopathy syndrome (PRES) continues to be enigmatic. We prospectively followed consecutive patients of PRES both clinically and radiologically for a better understanding of natural history, symptomatology, and prognosis of this not so uncommon entity. Patients and Methods:The current study included ... Read more >>

Ann Indian Acad Neurol (Annals of Indian Academy of Neurology)
[2020, 23(2):182-188]

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The determinants of neurological phenotypes during acute hypertensive crises - a preliminary study.

Mehmet Yasir Pektezel, Mehmet Akif Topcuoglu, Rahsan Gocmen, Bulent Erbil, Mehmet Mahir Kunt, Nalan Metin Aksu, Kader Karli Oguz, Ethem Murat Arsava,

Background and Purpose: Acute blood pressure elevations lead to wide spectrum of neurologic manifestations, ranging from no overt neurologic symptoms to catastrophic events like ICH. Little is known regarding the determinants of this clinical variability. We determined clinical and imaging features of hypertensive crisis patients with normal neurological examination, ICH ... Read more >>

Neurol. Res. (Neurological research)
[2020, 42(5):398-404]

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Diffusion MRI Findings in Encephalopathy Induced by Immunosuppressive Therapy after Liver Transplantation.

Emanuele Tinelli, Nicoletta Locuratolo, Alberto Pierallini, Massimo Rossi, Francesco Fattapposta,

Neurological complications are common after liver transplantation, as they affect up to one-third of the transplanted patients and are associated with significant morbidity. The introduction of calcineurin inhibitors, cyclosporine A and tacrolimus, in immunosuppressive regimens significantly improved the outcome of solid-organ transplantation even though immunosuppression-associated neurotoxicity remains a significant complication, ... Read more >>

Case Rep Med (Case reports in medicine)
[2020, 2020:1015385]

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Portal hypertensive gastropathy is associated with iron deficiency anemia.

Benedikt Simbrunner, Andrea Beer, Katharina Wöran, Fabian Schmitz, Christian Primas, Marlene Wewalka, Matthias Pinter, Werner Dolak, Bernhard Scheiner, Andreas Puespoek, Michael Trauner, Georg Oberhuber, Mattias Mandorfer, Thomas Reiberger,

BACKGROUND AND AIMS:Portal hypertensive gastropathy (PHG) is common in patients with cirrhosis and may cause bleeding. This study systematically explored the independent impact of patient characteristics, portal hypertension and hepatic dysfunction on PHG severity and associated anemia. METHODS:Patients with cirrhosis undergoing endoscopy were included in this retrospective analysis and PHG ... Read more >>

Wien. Klin. Wochenschr. (Wiener klinische Wochenschrift)
[2020, 132(1-2):1-11]

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Posterior Reversible Encephalopathy Syndrome: Clinical Features and Outcome.

Archana Hinduja,

Background: Posterior reversible encephalopathy syndrome (PRES) is an acute neurotoxic syndrome that is characterized by a spectrum neurological and radiological feature from various risk factors. Common neurological symptoms includes headache, impairment in level of consciousness, seizures, visual disturbances, and focal neurological deficits. Common triggering factors include blood pressure fluctuations, renal ... Read more >>

Front Neurol (Frontiers in neurology)
[2020, 11:71]

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Hypertensive brainstem encephalopathy: a diagnosis often overlooked.

Yin Yin Tan, Kenny Tan,

Hypertensive encephalopathy (HE) is a subset of posterior reversible encephalopathy syndrome. It typically involves the posterior supratentorial structures, but variations do occur. However, isolated brainstem involvement in HE is rare, with a few cases reported in the literature. Herein, we report a case of acute hypertensive brainstem encephalopathy in which ... Read more >>

Clin Med (Lond) (Clinical medicine (London, England))
[2019, 19(6):511-513]

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Clinical Profile and Immediate Outcome of Children Admitted With Acute Glomerulonephritis in Pediatrics Department of A Tertiary Level Hospital.

M Sharmin, A M Chowdhury, M A Ali, M W Rahman, M A Hossain, M H Rahman, P Sharmin, A S Roy, B Chowdhury,

Acute post-streptococcal glomerulonephritis (APSGN) is the commonest cause of acute glomerulonephritis (AGN), which usually present with gross hematuria, mild edema, oliguria, hypertension and varying degree of renal insufficiency. It is more common among the population of school going age where poverty, overcrowding and poor hygienic conditions are prevailing. This cross ... Read more >>

Mymensingh Med J (Mymensingh medical journal : MMJ)
[2020, 29(1):5-15]

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Balloon-occluded Retrograde Transvenous Obliteration Versus Transjugular Intrahepatic Portosystemic Shunt for Gastric Varices: A Meta-Analysis.

Qian Yu, Chenyu Liu, Driss Raissi,

INTRODUCTION:Balloon-occluded retrograde transvenous obliteration (BRTO) and transjugular intrahepatic portosystemic shunt (TIPS) are well-validated techniques in the management of portal hypertensive gastric variceal bleeding when medical management alone is not sufficient. However, despite their effectiveness, the adverse effects from both procedures make each technique more suitable to different cohorts of patient's ... Read more >>

J. Clin. Gastroenterol. (Journal of clinical gastroenterology)
[2019, :]

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Lower Gastrointestinal Bleeding in Patients With Cirrhosis-Etiology and Outcomes.

Ali Khalifa, Don C Rockey,

BACKGROUND:Lower gastrointestinal bleeding (LGIB) is a common clinical problem, and may be more prevalent among patients with cirrhosis, especially in the setting of portal hypertension and coagulopathy. However, there is extremely little data available on the subject of LGIB in patients with cirrhosis. Therefore, the primary objective of this study ... Read more >>

Am. J. Med. Sci. (The American journal of the medical sciences)
[2020, 359(4):206-211]

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[Malignant arterial hypertension (HTAM) with severe systolic dysfunction of the reversible left ventricle].

M S Cortés Fernández, J P Monteys Montblanch, P Castellanos Lleuger, P Armario,

Malignant arterial hypertension is still present in current clinical care despite the fact that for more than three decades we have had a wide range of antihypertensive drugs to control high blood pressure. It is essential to know how to detect it in time due to its high risk to ... Read more >>

Hipertens Riesgo Vasc (Hipertension y riesgo vascular)
[2019, :]

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Concurrent pituitary apoplexy and posterior reversible encephalopathy syndrome in a patient with end-stage renal disease on hemodialysis: A case report.

In Hee Lee, Ho Kyun Kim, Dong Jik Ahn,

RATIONALE:Pituitary apoplexy (PA) and posterior reversible encephalopathy syndrome (PRES) are rare neurologic diseases that show acute neuro-ophthalmologic symptoms such as headache, decreased visual acuity, and altered consciousness. These diseases are rarely found in patients with end-stage renal disease (ESRD) on hemodialysis, and simultaneous occurrence of these 2 diseases has not ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(5):e18987]

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'Blindness out of the womb', a historical account of the first report of posterior reversible encephalopathy syndrome (PRES): choose your title well or your findings will be neglected.

Wessel Ganzevoort, Kees Boterbloem, Joris van der Post, Otto Bleker,

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2020, 127(1):37-38]

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Posterior reversible encephalopathy syndrome with ischemic infarction complicated with intrauterine fetal death: A case report.

Wei-Chih Yeh, Li-Min Liou, Meng-Ni Wu,

RATIONALE:Posterior reversible encephalopathy syndrome (PRES), a rare neurologic disorder, manifests as headache, altered mental status, seizures, visual disturbances, and other focal neurologic signs with typically reversible clinical symptoms and image changes. Although the underlying mechanism remains unknown, a current theory indicates cerebral autoregulation failure as the primary cause. We report ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(4):e18877]

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Aortic Arch Calcification on routine Chest Radiography is Strongly and Independently Associated with Non-Dipper Blood Pressure Pattern.

Rui Póvoa,

Arq. Bras. Cardiol. (Arquivos brasileiros de cardiologia)
[2020, 114(1):118-119]

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Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.

Peipei Feng, Zemin Wu, Hao Liu, Yafang Shen, Xu Yao, Xinwei Li, Zui Shen,

Electroacupuncture (EA) can effectively alleviate anxiety disorders and memory impairments caused by various neurodegenerative diseases; however, the molecular mechanisms underlying its neuroprotective effects are unclear. Previous studies have shown that the renin-angiotensin system (RAS) comprises of two axes with mutual antagonism: the classical angiotensin converting enzyme/angiotensin II/angiotensin II type 1 ... Read more >>

Neural Plast. (Neural Plasticity)
[2020, 2020:9076042]

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Hypomagnesaemia induced recurrent cerebellar ataxia: an interesting case with successful management.

Singh Saraj Kumar, Goel Khushbu, Mukherji Joy Dev,

Purpose:Severe Hypomagnesaemia is a rare biochemical findings utilized for identifying the etiology of cerebellar ataxia. It requires a high degree of suspicion to diagnose. MRI findings are often nonspecific. Methods:The author presents a case of 38 yrs. old male patient presented with vomiting, gait imabalance and nystagmus. Biochemical investigations lead to ... Read more >>

Cerebellum Ataxias (Cerebellum & ataxias)
[2020, 7:1]

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Variant Type of Posterior Reversible Encephalopathy Syndrome Associated with Deep Brain Hemorrhage: Case Report and Review of the Literature.

Keitaro Yamagami, Yoshihisa Maeda, Koji Iihara,

BACKGROUND:Various radiologic patterns of posterior reversible encephalopathy syndrome (PRES) have been reported. Among them, PRES involving brainstem, thalamus, or deep white matter and lacking parieto-occipital edema is rare. Although PRES in general has a benign course, PRES-related intracranial hemorrhage has been associated with a poor prognosis. We report a case ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 134:176-181]

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Activation of the G Protein-Coupled Estrogen Receptor (GPER) Increases Neurogenesis and Ameliorates Neuroinflammation in the Hippocampus of Male Spontaneously Hypertensive Rats.

Julieta Correa, Santiago Ronchetti, Florencia Labombarda, Alejandro F De Nicola, Luciana Pietranera,

It is known that spontaneously hypertensive rats (SHR) present a marked encephalopathy, targeting vulnerable regions such as the hippocampus. Abnormalities of the hippocampus of SHR include decreased neurogenesis in the dentate gyrus (DG), partial loss of neurons in the hilus of the DG, micro and astrogliosis and inflammation. It is ... Read more >>

Cell. Mol. Neurobiol. (Cellular and molecular neurobiology)
[2019, :]

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Advanced Imaging Techniques in Diagnosis of Posterior Reversible Encephalopathy Syndrome (PRES).

Nasim Sheikh-Bahaei, Jay Acharya, Anandh Rajamohan, Paul E. Kim,

Diagnosis of Posterior Reversible Encephalopathy Syndrome (PRES) in some circumstances can be challenging and structural imaging may not be sufficient to distinguish it from other differential diagnostic considerations. Advanced imaging techniques, such as MR spectroscopy or positron emission tomography (PET) can provide additional information to determine the diagnosis. Other techniques, ... Read more >>

Front Neurol (Frontiers in Neurology)
[2020, 11:]

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Neuroprotective potential of azilsartan against cerebral ischemic injury: Possible involvement of mitochondrial mechanisms.

Varun Gupta, Dinesh K Dhull, Jyoti Joshi, Sukhbir Kaur, Anil Kumar,

AIMS:Mitochondrial dysfunction is a major player in initiating the cellular cascades which lead to neuronal damage post cerebral ischemia. Angiotensin II Type 1 (AT1) receptor blockers are one of the most commonly employed antihypertensive drugs due to their good safety and efficacy profiles. This study was designed to investigate the ... Read more >>

Neurochem. Int. (Neurochemistry international)
[2020, 132:104604]

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Protective effects of losartan on some type 2 diabetes mellitus-induced complications in Wistar and spontaneously hypertensive rats.

Daniela Pechlivanova, Ekaterina Krumova, Nedelina Kostadinova, Jeny Mitreva-Staleva, Petar Grozdanov, Alexander Stoynev,

Diabetes mellitus type 2 (T2DM) is characterized by resistance of insulin receptors and/or inadequate insulin secretion resulting in metabolic and structural complications including vascular diseases, arterial hypertension and different behavioral alterations. We aimed to study the effects of the antihypertensive angiotensin AT1 receptor antagonist losartan on the T2DM-induced changes of ... Read more >>

Metab Brain Dis (Metabolic brain disease)
[2020, 35(3):527-538]

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