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Hydrocarbons Toxicity

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Novel Aspects of Toxicity Mechanisms of Dioxins and Related Compounds.

Raimo Pohjanvirta, Matti Viluksela,

Dioxins and related compounds are common environmental contaminants. Although their levels have gone down, they are still of concern, in particular regarding developmental toxicity. The adverse effects of these compounds are mediated by the aryl hydrocarbon receptor (AHR), whose canonical signaling pathway has been unveiled in fair detail. The alternative ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(7):]

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Distribution, seasonal trends, and lung cancer risk of atmospheric polycyclic aromatic hydrocarbons in North China: A three-year case study in Dalian city.

Wen-Jun Hong, Hongliang Jia, Meng Yang, Yi-Fan Li,

Atmospheric monitoring data of polycyclic aromatic hydrocarbons (PAHs) over a three-year period were collected from an urban site in Dalian, northeast China. The status of PAHs in the atmosphere in Dalian were evaluated by assessing concentration levels, congener profiles, seasonal trends, primary source, inhalation exposure and the risk of developing ... Read more >>

Ecotoxicol. Environ. Saf. (Ecotoxicology and environmental safety)
[2020, 196:110526]

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Toxicity of three types of arsenolipids: species-specific effects in Caenorhabditis elegans.

Julia Bornhorst, Franziska Ebert, Sören Meyer, Vanessa Ziemann, Chan Xiong, Nikolaus Guttenberger, Andrea Raab, Jessica Baesler, Michael Aschner, Jörg Feldmann, Kevin Francesconi, Georg Raber, Tanja Schwerdtle,

Although fish and seafood are well known for their nutritional benefits, they contain contaminants that might affect human health. Organic lipid-soluble arsenic species, so called arsenolipids, belong to the emerging contaminants in these food items; their toxicity has yet to be systematically studied. Here, we apply the in vivo model ... Read more >>

Metallomics (Metallomics : integrated biometal science)
[2020, :]

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Legacy and current-use contaminants in sediments alter macroinvertebrate communities in southeastern USA streams.

Patrick W Moran, Nile E Kemble, Ian R Waite, Barbara J Mahler, Lisa H Nowell, Peter C Van Metre,

Sediment contamination in freshwater streams in urban areas is a recognized and growing concern. As a part of a comprehensive regional stream-quality assessment, streambed sediment was sampled from streams spanning a gradient of urban intensity in the Piedmont ecoregion of the southeastern United States. We evaluated relations between a broad ... Read more >>

Environ. Toxicol. Chem. (Environmental toxicology and chemistry)
[2020, :]

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QSAR modeling with ETA indices for cytotoxicity and enzymatic activity of diverse chemicals.

Arnab Seth, Probir Kumar Ojha, Kunal Roy,

The discharge of huge amount of chemicals from industries into the environment has led to toxicity towards different living species. Therefore, risk assessment of these chemicals is essential. In order to comply with the ethical issues, in this present work, we have developed quantitative structure-activity relationship (QSAR) models for cytotoxicity ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 394:122498]

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Theoretical investigation of AhR binding property with relevant structural requirements for AhR-mediated toxicity of polybrominated diphenyl ethers.

Chenggang Gu, Jun Cai, Xiuli Fan, Yongrong Bian, Xinglun Yang, Qiying Xia, Cheng Sun, Xin Jiang,

Polybrominated diphenyl ethers (PBDEs) are more frequently suspected with the induction of toxicity via signal transduction pathway of cytosolic aryl hydrocarbon receptor (AhR), the initial binding to which is assumed to be an essential prerequisite during the ligand-dependent activation. However, the AhR binding property and associated toxicity of PBDEs is ... Read more >>

Chemosphere (Chemosphere)
[2020, 249:126554]

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Comparative genotoxic potential of 27 polycyclic aromatic hydrocarbons in three human cell lines.

F Tomasetig, C Tebby, V Graillot, F Zeman, A Pery, J P Cravedi, M Audebert,

Polycyclic Aromatic Hydrocarbons (PAHs) form a family of compounds that are generally found in complex mixtures. PAHs can lead to the development of carcinogenesis. The Toxicity Equivalent Factor (TEF) approach has been suggested for estimating the toxicity of PAHs, however, due to the relative weakness of available data, TEF have ... Read more >>

Toxicol. Lett. (Toxicology letters)
[2020, 326:99-105]

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Skeletal Toxicity of Coplanar Polychlorinated Biphenyl Congener 126 in the Rat is Aryl Hydrocarbon Receptor-Dependent.

A E Williams, J Watt, L W Robertson, G Gadupudi, M L Osborn, M J Soares, K Iqbal, K B Pedersen, Kartik Shankar, S Littleton, C Maimone, N A Eti, L J Suva, M J J Ronis,

Epidemiological evidence links polychlorinated biphenyls (PCBs) to skeletal toxicity, however mechanisms whereby PCBs affect bone are poorly studied. In this study, coplanar PCB 126 (5 μmol/kg) or corn oil vehicle was administered to N = 5-6 male and female, wild type (WT) or AhR-/- rats via intraperitoneal injection. Animals were sacrificed after four ... Read more >>

Toxicol. Sci. (Toxicological sciences : an official journal of the Society of Toxicology)
[2020, :]

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Nationwide health risk assessment of juvenile exposure to polycyclic aromatic hydrocarbons (PAHs) in the water body of Chinese lakes.

Yong He, Chen Yang, Wei He, Fuliu Xu,

The high emissions of polycyclic aromatic hydrocarbons (PAHs) pose a serious threat to the lake ecosystem and human health, and the human health risk assessment of PAH exposure is expected as an urgent project in China. This paper focused on 44 Chinese lakes in 6 lake zones to investigate the ... Read more >>

Sci. Total Environ. (The Science of the total environment)
[2020, 723:138099]

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Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds.

Melissa Schepers, Nikita Martens, Assia Tiane, Kenneth Vanbrabant, Hong-Bing Liu, Dieter Lütjohann, Monique Mulder, Tim Vanmierlo,

Edible marine algae, or seaweeds, are a rich source of several bioactive compounds including phytosterols, carotenoids, and polysaccharides. Over the last decades, seaweed-derived constituents turned out to not only reside in the systemic circulation, but are able to cross the blood-brain barrier to exert neuro-active functions both in homeostatic and ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(5):790-795]

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Additive toxicity of Co-exposure to pristine multi-walled carbon nanotubes and benzo α pyrene in lung cells.

Mansour Rezazadeh Azari, Yousef Mohammadian, Jalal Pourahmad, Fariba Khodagholi, Yadollah Mehrabi,

The Mixture exposure to pristine multi-walled carbon nanotubes (P-MWCNTs) and polycyclic aromatic hydrocarbons (PAHs) such as benzo α pyrene (BaP) in the environment is inevitable. Assessment toxicity of P-MWCNTs and BaP individually may not provide sufficient toxicological information. The objective of this work is to investigate the combined toxicity of ... Read more >>

Environ. Res. (Environmental research)
[2020, 183:109219]

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Terrestrial Toxicity of Synthetic Gas-to-Liquid versus Crude Oil-Derived Drilling Fluids in Soil.

Lisa Arneson Westbrook, Darcy A Chase, Joseph Mudge, Sarah A Hughes, Delina Lyon, Meijun Dong, Deborah Carr, Todd A Anderson,

Unlike most other conventional petroleum products that are derived from crude oil, gas-to-liquids (GTLs) are petroleum products that are synthesized from natural gas (methane). This process results in GTL products having no sulfur and low aromatic content, so they should have less impact on human health and the environment compared ... Read more >>

Environ. Toxicol. Chem. (Environmental toxicology and chemistry)
[2020, 39(3):721-730]

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Exposure to Crude Oil Induces Retinal Apoptosis and Impairs Visual Function in Fish.

Jason T Magnuson, Naim M Bautista, JoAnn Lucero, Amie K Lund, Elvis Genbo Xu, Daniel Schlenk, Warren W Burggren, Aaron P Roberts,

Polycyclic aromatic hydrocarbons (PAHs) present in crude oil are known to impair visual development in fish. However, the underlying mechanism of PAH-induced toxicity to the visual system of fish is not understood. Embryonic zebrafish (Danio rerio) at 4 h post fertilization were exposed to weathered crude oil and assessed for ... Read more >>

Environ. Sci. Technol. (Environmental science & technology)
[2020, 54(5):2843-2850]

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Smoking cessation and duloxetine toxicity: A case report.

Nadia Tancredi, Neha Kohli,

OBJECTIVE:Psychiatric medications are among the drugs affected by cigarette smoke, and because of the high prevalence of smoking in the psychiatric community, psychiatric patients are particularly at risk when entering the smoke-free environment of a hospital. CASE SUMMARY:Polycyclic aromatic hydrocarbons present in cigarette smoke are well-known inducers of cytochrome P450 ... Read more >>

J Am Pharm Assoc (2003) (Journal of the American Pharmacists Association : JAPhA)
[2020, :]

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Disappearance kinetics of 56 toxic semi-volatile organic compounds under common storage conditions.

Ochan Otim, Jesus Rocha,

Synthetic semi-volatile organic compounds (SVOCs) are widely distributed in the environment due to their ever expanding uses. But because some are hazardous, their presence in matrices such as indoor air, wastewater, fish tissue and marine sediment samples (where they could adversely impact public health and the environment) is carefully monitored. ... Read more >>

Environ Sci Process Impacts (Environmental science. Processes & impacts)
[2020, 22(3):833-847]

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Hydrocarbon Removal by Two Differently Developed Microbial Inoculants and Comparing Their Actions with Biostimulation Treatment.

Joanna Brzeszcz, Piotr Kapusta, Teresa Steliga, Anna Turkiewicz,

Bioremediation of soils polluted with petroleum compounds is a widely accepted environmental technology. We compared the effects of biostimulation and bioaugmentation of soil historically contaminated with aliphatic and polycyclic aromatic hydrocarbons. The studied bioaugmentation treatments comprised of the introduction of differently developed microbial inoculants, namely: an isolated hydrocarbon-degrading community C1 ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2020, 25(3):]

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Reduction of polycyclic compounds and biphenyls generated by pyrolysis of industrial plastic waste by using supported metal catalysts: A case study of polyethylene terephthalate treatment.

Soosan Kim, Chanyeong Park, Jechan Lee,

The accumulation of industrial plastic waste in the environment is a global growing concern. Thermochemical process is a preferred method to dispose plastic waste mainly because it can reduce volume of the waste; however, the thermochemical disposal of plastic waste can emit harmful chemical species such as benzene derivatives and ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 392:122464]

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Species-specific sensitivity of three microalgae to sediment elutriates.

A Gallo, M Guida, G Armiento, A Siciliano, N Mormile, F Carraturo, D Pellegrini, L Morroni, E Tosti, M I Ferrante, M Montresor, F Molisso, M Sacchi, R Danovaro, G Lofrano, G Libralato,

Microalgae are considered good bioindicators of marine environmental quality. Frequently, they are used to investigate the toxicity of sediment elutriates, but their sensitivity is disputed. This paper compared the sensitivity of Phaeodactylum tricornutum (diatom), Skeletonema costatum (diatom), and Dunaliella tertiolecta (green alga), analyzing 257 samples of elutriates (1:4 sediment: water ... Read more >>

Mar. Environ. Res. (Marine environmental research)
[2020, 156:104901]

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Long-term trends of persistent toxic substances and potential toxicities in sediments along the west coast of South Korea.

Seonju Kim, Seongjin Hong, Junghyun Lee, Taewoo Kim, Seo Joon Yoon, Jongmin Lee, Kyungsik Choi, Bong-Oh Kwon, John P Giesy, Jong Seong Khim,

For decades, in response to industrialization and urbanization, environmental qualities of estuarine and coastal areas of the west coast of Korea have been deteriorating. Long-term changes in concentrations of persistent toxic substances (PTSs) in sediments, including PAHs, styrene oligomers, nonylphenols, and metals and their potential toxicities via AhR- and ER-mediated ... Read more >>

Mar. Pollut. Bull. (Marine pollution bulletin)
[2020, 151:110821]

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How will marine plastic pollution affect bacterial primary producers?

Sasha G Tetu, Indrani Sarker, Lisa R Moore,

Commun Biol (Communications biology)
[2020, 3(1):55]

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Acute and Chronic Carbon Monoxide Toxicity from Tobacco Smoking.

Alyrene Dorey, Pieter Scheerlinck, Hoanvu Nguyen, Timothy Albertson,

INTRODUCTION:Carbon monoxide (CO) is produced from incomplete combustion of hydrocarbons and is a by-product of tobacco smoking. Chronic cigarette smokers often have carboxyhemoglobin (COHb) concentrations as high as 10%. We report a case of severely elevated COHb and polycythemia because of tobacco smoking and provide a review of the literature ... Read more >>

Mil Med (Military medicine)
[2020, 185(1-2):e61-e67]

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Assessment of Biodegradation Efficiency of Polychlorinated Biphenyls (PCBs) and Petroleum Hydrocarbons (TPH) in Soil Using Three Individual Bacterial Strains and Their Mixed Culture.

Teresa Steliga, Katarzyna Wojtowicz, Piotr Kapusta, Joanna Brzeszcz,

Biodegradation is one of the most effective and profitable methods for the elimination of toxic polychlorinated biphenyls (PCBs) and total petroleum hydrocarbons (TPH) from the environment. In this study, aerobic degradation of the mentioned pollutants by bacterial strains Mycolicibacterium frederiksbergense IN53, Rhodococcus erythropolis IN129, and Rhodococcus sp. IN306 and mixed ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2020, 25(3):]

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Organic pollutants in sedimentary microplastics from eastern Guangdong: Spatial distribution and source identification.

Jingchun Shi, Edmond Sanganyado, Lisi Wang, Ping Li, Xiang Li, Wenhua Liu,

Microplastics have a strong affinity for potentially toxic organic pollutants such as polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs). Since 2005, the International Pellet Watch used plastic pellets to monitor hydrophobic organic contaminants in marine environments. We examined the spatial distribution and sources of 16 PAHs and eight OCPs ... Read more >>

Ecotoxicol. Environ. Saf. (Ecotoxicology and environmental safety)
[2020, 193:110356]

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Generation and application of a Tg(cyp1a:egfp) transgenic marine medaka (Oryzias melastigma) line as an in vivo assay to sensitively detect dioxin-like compounds in the environment.

Yixi Zhou, Chao Shen, Jinpeng Ruan, Chengyong He, Meng Chen, Chonggang Wang, Zhenghong Zuo,

Large-range environmental pollution by dioxin and dioxin-like compounds (DLCs) is becoming a serious problem. To establish an in vivo method for the detection of DLCs in seawater, a Tg(cyp1a-12DRE:egfp) transgenic marine medaka (Oryzias melastigma) line was first developed with the modified cyp1a-12DRE promoter driving enhanced green fluorescent protein (EGFP) expression ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 391:122192]

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Monitoring oil contamination in vegetated areas with optical remote sensing: A comprehensive review.

Guillaume Lassalle, Sophie Fabre, Anthony Credoz, Dominique Dubucq, Arnaud Elger,

The monitoring of soil contamination deriving from oil and gas industry remains difficult in vegetated areas. Over the last decade, optical remote sensing has proved helpful for this purpose. By tracking alterations in vegetation biochemistry through its optical properties, multi- and hyperspectral remote sensing allow detecting and quantifying crude oil ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 393:122427]

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