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Full Text Journal Articles about
Histoplasmosis

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Histoplasmosis of the Upper Extremities: Clinical Case, Treatment Algorithm, and Systematic Review.

Maria T Huayllani, David J Restrepo, Daniel Boczar, Andrea Sisti, Brian D Rinker, Oscar J Manrique, Galen Perdikis, Antonio J Forte,

Background: Histoplasmosis of the upper extremities is extremely rare, and there is no consensus in its management. The aim of this study was to present a case report and literature review of histoplasmosis in the upper extremities to provide the best treatment recommendation and to increase awareness of this disease. ... Read more >>

Hand (N Y) (Hand (New York, N.Y.))
[2020, :1558944720911212]

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Presumed ocular histoplasmosis syndrome in a commercially insured population, United States.

Kaitlin Benedict, Jessica G Shantha, Steven Yeh, Karlyn D Beer, Brendan R Jackson,

PURPOSE:To describe epidemiologic features of patients with presumed ocular histoplasmosis syndrome (POHS) in the United States using insurance claims data and compare POHS patients with and without choroidal neovascularization (CNV). DESIGN:Retrospective cohort study. METHODS:Patients with International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes for histoplasmosis retinitis on an ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0230305]

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Histoplasmosis-related Healthcare Use, Diagnosis, and Treatment in a Commercially Insured Population, United States.

Kaitlin Benedict, Karlyn D Beer, Brendan R Jackson,

BACKGROUND:Infections with Histoplasma can range from asymptomatic to life-threatening acute pulmonary or disseminated disease. Histoplasmosis can be challenging to diagnose and is widely underrecognized. We analyzed insurance claims data to better characterize histoplasmosis testing and treatment practices and its burden on patients. METHODS:We used the IBM MarketScan Research Databases to ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(6):1003-1010]

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HIV patients dying on anti-tuberculosis treatment: are undiagnosed infections still a problem in French Guiana?

mathieu nacher, Antoine Adenis, Philippe Abboud, Felix Djossou, Magalie Demar, Loïc Epelboin, Pierre Couppié,

<title>Abstract</title> <p> Objective Despite scaling-up testing and antiretroviral treatment in Latin America, advanced HIV remains a significant public health problem. The objective of the present study was look for historical risk factors for death in French Guiana’s HIV cohort taking into account the immunological status, the main opportunistic ... Read more >>

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Histoplasmosis in Inflammatory Bowel Disease with Tumor Necrosis Factor-Alpha Inhibitors: Safe to Continue Biologics?

Claire L Jansson-Knodell, Courtney E Harris, Edward V Loftus, Randall C Walker, Mark J Enzler, Abinash Virk,

BACKGROUND:The advent of tumor necrosis factor-α (TNF-α) inhibitor therapy has transformed inflammatory bowel disease management; however, these medications carry a boxed warning for risk of serious infections, including invasive fungal infections. AIMS:We aimed to study the clinical features, severity, and outcomes of histoplasmosis in patients on TNF-α inhibitors for IBD. ... Read more >>

Dig. Dis. Sci. (Digestive diseases and sciences)
[2020, :]

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Mapping priority neighborhoods: A novel approach to cluster identification in HIV/AIDS population

Soushieta Jagadesh, Marine Combe, Pierre Couppié, Rodolphe Gozlan, Mathieu Nacher,

<title>Abstract</title> <p> BackgroundUrban disadvantaged neighborhoods have higher HIV risk behavior and higher levels of AIDS-related mortality. Studies demonstrate that interventions at the community level focusing on risk groups have increased success rates than individual patient-based based management in the context of HIV/AIDS. We tested a novel approach to ... Read more >>

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A Case of Histoplasmosis with Central Nervous System Relapse after Itraconazole Therapy Needs Further Research.

Prashanth Peddi, Tejo Challa, Sreenath Meegada, Madhavi Annakula, Evan Mar,

Central nervous system (CNS) histoplasmosis occurs in 5-20% of all cases and is most commonly seen in immunosuppressed patients who have acquired immunodeficiency syndrome (AIDS) or have received organ transplant. The prevalence of histoplasmosis in patients greater than 65 years old between the years of 1999-2008 in the state of ... Read more >>

Cureus (Cureus)
[2020, 12(2):e7064]

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Colonic Infection by Histoplasma capsulatum in a Liver Transplant Patient: A Case Report.

Gustavo de Sousa Arantes Ferreira, André Luis Conde Watanabe, Natália de Carvalho Trevizoli, Fernando Marcus Felippe Jorge, Priscila Brizolla de Camposa, Carolina de Fatima Couto, Laura Viana de Lima, Deborah Roberta Liduario Raupp,

Histoplasmosis is an infection caused by the dimorphic fungus Histoplasma capsulatum. While the lungs are the most common site of infection, disseminated disease affecting multiple organs can occur, particularly in immunocompromised patients. Gastrointestinal histoplasmosis is usually diagnosed in the context of disseminated disease and can present in any part of ... Read more >>

Transplant. Proc. (Transplantation proceedings)
[2020, :]

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Pyrexia of unknown origin in HIV-negative adults from Himachal Pradesh (India): will you suspect disseminated histoplasmosis?

Navneet Arora, Shubham Shukla, Deeksha Vijaykumar, Vikas Suri, Rajender Kumar, Ashok K Pannu,

Histoplasmosis is usually clinically suspected only in people who reside in, are migrants from or are travelling to endemic areas such as North America. Immunocompetent patients with a low level of exposure typically have either subclinical or mild and self-limiting infection. The most common risk for the development of progressive ... Read more >>

Trop Doct (Tropical doctor)
[2020, :49475520908725]

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Histoplasmosis in HIV-Infected Patients: Epidemiological, Clinical and Necropsy Data from a Brazilian Teaching Hospital.

Alessandro Henrique Damasceno-Escoura, Delio José Mora, Anderson Clayton Cardeal, Júlio Cesar Berto-Nascimento, Renata Margarida Etchebehere, Antônio Carlos Oliveira de Meneses, Sheila Jorge Adad, Adilha Misson Rua Micheletti, Mario León Silva-Vergara,

Histoplasmosis occurs in 5-10% of HIV-infected patients in endemic areas and evolves to severe and disseminated infection with mortality rates over 50% in some regions. This report presents epidemiological, clinical and outcome data from HIV-infected patients with histoplasmosis confirmed by culture and/or at necropsy who were admitted to a Brazilian ... Read more >>

Mycopathologia (Mycopathologia)
[2020, 185(2):339-346]

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Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis.

Vaibhav Agrawal, Bryan J Brinda, Sherif S Farag,

Histoplasma capsulatum infection is a rare complication in the allogeneic stem cell transplant patients. Minimal guidance exists on how to appropriately manage histoplasmosis in these patients. We report a patient who developed Histoplasma pneumonia while receiving voriconazole prophylaxis at a therapeutic trough level. The patient experienced significant clinical improvement after ... Read more >>

Case Rep Hematol (Case reports in hematology)
[2020, 2020:8124137]

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A Case of Histoplasma duboisii Brain Abscess and Review of the Literature.

Landry Konan, Landry Drogba, Doukoure Brahima, Fassil B Mesfin,

Histoplasmosis is a fungal disease caused by Histoplasma capsulatum var. capsulatum (Hcc) and H. capsulatum var. duboisii (Hcd). Central nervous system (CNS) involvement is rare. So far, the few cases reported having Histoplasmosis associated brain abscesses were caused by H. capsulatum var. capsulatum. Herein, we report a unique case of brain abscess caused by H. capsulatum ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6984]

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Clinical features and endemic trend of histoplasmosis in China: A retrospective analysis and literature review.

Xin Lv, Mao Jiang, Rongling He, Mengyu Li, Jie Meng,

INTRODUCTION:Histoplasmosis is a rare mycosis with nonspecific clinical manifestation and a high misdiagnosis rate, which is an epidemic disease that occurred in several endemic areas. Cases of histoplasmosis were sporadic in China. OBJECTIVE:We detected the clinical characteristics and endemic trend of histoplasmosis to understand it more profoundly. METHOD:The clinical data of 34 cases ... Read more >>

Clin Respir J (The clinical respiratory journal)
[2020, 14(4):307-313]

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What is AIDS in the Amazon and the Guianas in the 90-90-90 era?

Mathieu Nacher, Antoine Adenis, Basma Guarmit, Aude Lucarelli, Denis Blanchet, Magalie Demar, Felix Djossou, Philippe Abboud, Loïc Epelboin, Pierre Couppié,

Introduction In the past decade, new diagnostic methods and strategies have appeared, HIV testing efforts and the generalization of antiretroviral therapy may have influenced the number of opportunistic diagnoses and mortality of HIV-infected patients. To test this hypothesis we compiled data on the top opportunistic infections and causes of early ... Read more >>

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Disseminated Histoplasmosis with Concurrent Hairy Cell Leukemia.

Abdul Moiz Khan, Sheikh Raza Shahzad, Saleh Najjar, Llewellyn Foulke,

Histoplasmosis is an endemic fungal infection that can lead to disseminated disease, especially in immunosuppressed patients. Hairy cell leukemia is a rare, slow-growing hematological malignancy. Concurrence of histoplasmosis and hairy cell leukemia is extremely rare. We describe a 69-year-old male who presented with fever, dry cough, pancytopenia, multiple pulmonary nodules, ... Read more >>

Cureus (Cureus)
[2020, 12(1):e6825]

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Incidence and Trends in Immune Reconstitution Inflammatory Syndrome Associated With Histoplasma capsulatum Among People Living With Human Immunodeficiency Virus: A 20-Year Case Series and Literature Review.

Alessia Melzani, Regis de Reynal de Saint Michel, Balthazar Ntab, Felix Djossou, Loic Epelboin, Mathieu Nacher, Denis Blanchet, Magalie Demar, Pierre Couppie, Antoine Adenis,

BACKGROUND:Histoplasmosis is among the main acquired immunodeficiency syndrome (AIDS)-defining conditions in endemic areas. Although histoplasmosis has a worldwide distribution, histoplasmosis-associated immune reconstitution inflammatory syndrome (IRIS) in people living with human immunodeficiency virus (PLHIV) is rarely reported.This study aimed to describe the incidence and features of histoplasmosis-associated IRIS in a cohort ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(4):643-652]

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Current Concepts in the Epidemiology, Diagnosis, and Management of Histoplasmosis Syndromes.

Marwan M Azar, James L Loyd, Ryan F Relich, L Joseph Wheat, Chadi A Hage,

Histoplasmosis is a global disease endemic to regions of all six inhabited continents. The areas of highest endemicity lie within the Mississippi and Ohio River Valleys of North America and parts of Central and South America. As a result of climate change and anthropogenic land utilization, the conditions suitable for ... Read more >>

Semin Respir Crit Care Med (Seminars in respiratory and critical care medicine)
[2020, 41(1):13-30]

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Acute histoplasmosis in travelers: a retrospective study in an Italian referral center for tropical diseases.

Silvia Staffolani, Niccolò Riccardi, Claudio Farina, Giuliana Lo Cascio, Maurizio Gulletta, Federico Gobbi, Paola Rodari, Tamara Ursini, Giulia Bertoli, Niccolò Ronzoni, Zeno Bisoffi, Andrea Angheben,

Purpose: Histoplasmosis is a fungal infection acquired through inhalation of Histoplasma capsulatum microconidia, mostly present in the Americas. Both immunocompetent and immunocompromised patients can present a wide spectrum of signs/symptoms, ranging from mild disease to a severe, disseminated infection. The aim of this observational study is to describe histoplasmosis cases ... Read more >>

Pathog Glob Health (Pathogens and global health)
[2020, 114(1):40-45]

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Case Report: Histoplasmosis Accompanying Disseminated Tuberculosis in an Immunocompetent Adolescent Boy.

Ashis Kumar Choudhury, Ankit Kumar Mishra, Deepak Kumar Gautam, Ragini Tilak, Vijai Tilak, Indrajeet Singh Gambhir, Sankha Shubhra Chakrabarti,

The incidence of tuberculosis in India is quite high. In such a situation, empirical antitubercular therapy (ATT) is often resorted to, when some of the investigation findings are clearly diagnostic of tuberculosis. This may mean missing out on coinfections. Whereas this is particularly true for immunosuppressed patients, rarely even immunocompetent ... Read more >>

Am. J. Trop. Med. Hyg. (The American journal of tropical medicine and hygiene)
[2020, 102(2):352-354]

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Indigenous recurrent disseminated histoplasmosis in Taiwan.

Hung-I Kuo, Xin-Min Liao, Szu-Chun Yang, Jen-Chieh Lee, Kung-Chao Chang, Cong-Tat Cia,

J Microbiol Immunol Infect (Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi)
[2020, :]

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Postpartum histoplasmosis in an HIV-negative woman: a case report and phylogenetic characterization by internal transcribed spacer region analysis.

Lisandra Serra Damasceno, Antônio Mauro Barros Almeida Júnior, Bárbara de Oliveira Aguiar, Mauro de Medeiros Muniz, Marcos de Abreu Almeida, Rosely Maria Zancopé-Oliveira, Terezinha do Menino Jesus Silva Leitão,

The present report describes the first case of postpartum disseminated histoplasmosis in a 24-year-old HIV-negative woman. On the tenth day after vaginal delivery, the patient presented with dyspnea, fever, hypotension, tachycardia, and painful hepatomegaly. Yeast-like Histoplasma capsulatum features were isolated in the buffy coat. The phylogenetic analysis demonstrated that the ... Read more >>

Rev. Soc. Bras. Med. Trop. (Revista da Sociedade Brasileira de Medicina Tropical)
[2020, 53:e20190364]

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Current burden of serious fungal infections in Republic of Congo.

Fructueux M Amona, David W Denning, Donatien Moukassa, Christophe Hennequin,

BACKGROUND:The Republic of Congo (RoC) is characterized by a high prevalence of tuberculosis and HIV/AIDS, which largely drive the epidemiology of serious fungal infections. OBJECTIVE:We aimed to estimate the current burden of serious fungal infections in RoC. MATERIAL AND METHODS:Using local, regional, or global data and estimates of population and ... Read more >>

Mycoses (Mycoses)
[2020, :]

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Reactivation of Histoplasmosis Disseminated into the Central Nervous System Presenting as a Stroke.

Linda Klumpp, Gustine Liu-Young, Fagun Modi, Jeffrey Jordan, Rony Shah,

Histoplasmosis is one of the most prevalent endemic mycosis in the United States. Patients with a previous history of histoplasmosis have a risk of reinfection in the future. Individuals with impaired immunity and those who have massive re-exposure to H. capsulatum, their defenses against this organism can be overwhelmed and ... Read more >>

Cureus (Cureus)
[2019, 11(12):e6525]

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Histoplasmosis: Time to Redraw the Map and Up Our Game.

David S McKinsey, Peter G Pappas,

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(6):1011-1013]

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[Histoplasmosis in Argentina: case series in children].

Carla Voto, M Guadalupe Pérez, Sandra Gómez, Carolina Epelbaum, Claudia Sarkis, Patricia Santos, Susana Carnovale, Cristina Canteros, Rosa Bologna,

BACKGROUND:Histoplasmosis is a fungal disease, endemic in South America, and seldom reported in paediatrics. AIMS:To report the epidemiology, clinical features and outcome of children diagnosed with histoplasmosis in an Argentinian Children's Hospital. METHODS:A retrospective and descriptive study was performed from January 2008 to December 2016 in Hospital de Pediatría 'Prof. ... Read more >>

Rev Iberoam Micol (Revista iberoamericana de micologia)
[2020, 37(1):34-36]

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