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Deletion of a putative HDA-1 binding site in the hlh-2 promoter eliminates expression in C. elegans dorsal uterine cells.

Taylor N Medwig-Kinney, Nicholas J Palmisano, David Q Matus,

The helix-loop-helix transcription factor <i>hlh-2</i> (E/Daughterless) has been shown to play an important role in regulating cell fate patterning, cell cycle, and basement membrane invasion in the context of the development of the <i>C. elegans</i> somatic gonad. Here, using CRISPR/Cas9 genome engineering, we generated a new <i>hlh-2</i> allele (<i>hlh-2(Δ-1303-702)</i>) in ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Caspar SUMOylation regulates Drosophila lifespan.

Bhagyashree Kaduskar, Deepti Trivedi, Girish S Ratnaparkhi,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 0 times

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Establishment of a CRISPR/Cas9-based strategy for inducible protein dimerization.

Jeffrey Zielich, Sriyash Mangal, Esther Zanin, Eric Lambie,

MicroPubl Biol (microPublication biology)
[2018, 2018:]

Cited: 0 times

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SapTrap assembly of repair templates for Cas9-triggered homologous recombination with a self-excising cassette.

Daniel Dickinson, Mark Slabodnick, Alicia Chen, Bob Goldstein,

MicroPubl Biol (microPublication biology)
[2018, 2018:]

Cited: 8 times

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Clinical potential of tension-lengthening strategies during nerve repair.

Stanley Bazarek, Justin M Brown, Sameer B Shah,

Neural Regen Res (Neural regeneration research)
[2022, 17(4):779-780]

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Axonal protein synthesis in central nervous system regeneration: is building an axon a local matter?

Julia Schaeffer, Stephane Belin,

Neural Regen Res (Neural regeneration research)
[2022, 17(5):987-988]

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The Hsp90-binding immunophilin FKBP52 enhances neurodifferentiation and neuroregeneration in murine models.

Cristina Daneri-Becerra, Mario D Galigniana,

Neural Regen Res (Neural regeneration research)
[2022, 17(3):555-556]

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From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson's disease?

Rita Caridade Silva, Helena Sofia Domingues, António J Salgado, Fábio G Teixeira,

Parkinson's disease is the second most prevalent neurodegenerative disorder worldwide. Clinically, it is characterized by severe motor complications caused by progressive degeneration of dopaminergic neurons. Current treatment is focused on mitigating the symptoms through the administration of levodopa, rather than on preventing dopaminergic neuronal damage. Therefore, the use and development ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(5):933-936]

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The emerging world of subcellular biological medicine: extracellular vesicles as novel biomarkers, targets, and therapeutics.

Leon G Coleman,

Neural Regen Res (Neural regeneration research)
[2022, 17(5):1020-1022]

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Significance of intercellular communication for neurodegenerative diseases.

Hilal Cihankaya, Carsten Theiss, Veronika Matschke,

Neural Regen Res (Neural regeneration research)
[2022, 17(5):1015-1017]

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Paediatric Burns of the Hand: Our Experience Over Three Years

Dujanah S Bhatti, Rafsan Chowdhury, Kok Kiong Ang, Jennifer Greenhowe,

Background and aim Contact burn injuries to the hand are common in the paediatric population, with the most common aetiology involving touching hot surfaces in the household. The hand is also often involved in paediatric scald injuries. The aim of this study was to determine the different presentations of hand ... Read more >>

Cureus (Cureus)
[0, 13(10):]

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Functional and immunological peculiarities of peripheral nerve allografts.

Kelly C S Roballo, Jason P Gigley, Tyler A Smith, George D Bittner, Jared S Bushman,

This review addresses the accumulating evidence that live (not decellularized) allogeneic peripheral nerves are functionally and immunologically peculiar in comparison with many other transplanted allogeneic tissues. This is relevant because live peripheral nerve allografts are very effective at promoting recovery after segmental peripheral nerve injury via axonal regeneration and axon ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(4):721-727]

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Surgical Reconstruction of Severe Tophaceous Gout in the Hand: A Customized Approach

Mariarosaria Galeano, Michele R. Colonna, Sandra Pfanner, Massimo Ceruso,

Summary: Tophaceous gout can represent a major problem for hand surgeons when it turns into aggressive nodules, spreading and destroying soft tissue and bone. The combination of ablative and reconstructive surgery may also be complex when the patient refuses amputations and multiple segments are involved. We present a difficult case, ... Read more >>

Plast Reconstr Surg Glob Open (Plastic and reconstructive surgery. Global open)
[2021, 9(11):]

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Is Left Ventricular Assist Device Deactivation Ethically Acceptable? A Study on the Euthanasia Debate.

Sara Roggi, Mario Picozzi,

In the last decades, new technologies have improved the survival of patients affected by chronic illnesses. Among them, left ventricular assist device (LVAD) has represented a viable solution for patients with advanced heart failure (HF). Even though the LVAD prolongs life expectancy, patients' vulnerability generally increases during follow up and ... Read more >>

HEC Forum (HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues)
[2021, 33(4):325-343]

Cited: 1 time

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Long-term outcome of lymph vessel transplantation after chronic lymphorrhea

Cecilia Dahlbäck, Rüdiger Baumeister, Magnus Åberg, Björn Arnljots, Lieselotte Frost Arner, Håkan Brorson,

Abstract A 52-year-old male patient developed a chronic fistula with excessive lymph leakage in the left axilla following removal of an enlarged lymph node with chronic local adipose tissue inflammation due to infection. After multiple surgeries, treatment with lymphatic vessel transplantation was successful. No recurrence occurred over 20 years of ... Read more >>

Case Reports Plast Surg Hand Surg (Case reports in plastic surgery & hand surgery)
[2021, 8(1):169-174]

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Surgical Reconstruction of Severe Tophaceous Gout in the Hand: A Customized Approach.

Mariarosaria Galeano, Michele R Colonna, Sandra Pfanner, Massimo Ceruso,

Tophaceous gout can represent a major problem for hand surgeons when it turns into aggressive nodules, spreading and destroying soft tissue and bone. The combination of ablative and reconstructive surgery may also be complex when the patient refuses amputations and multiple segments are involved. We present a difficult case, where ... Read more >>

Plast Reconstr Surg Glob Open (Plastic and reconstructive surgery. Global open)
[2021, 9(11):e3912]

Cited: 0 times

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Hemi-tibia allograft and free microvascularized fibula transplant reconstitute the tibia shaft with side to side healing: 7 year follow up of a 14-year-old boy with adamantinoma

Alexander P. Decilveo, Melissa S. Liebling, Andrew L. Golden, James C. Wittig,

Abstract Adamantinoma is a malignant tumor that usually presents in adult men between 20 and 50 years. Due to its metastatic potential, differentiating Adamantinoma from Osteofibrous dysplasia is essential as treatment varies greatly. We present a case of limb salvage using a free microvascularized fibula transplant and hemi-tibia allograft. ... Read more >>

Case Reports Plast Surg Hand Surg (Case reports in plastic surgery & hand surgery)
[2021, 8(1):175-180]

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Proximal Humeral Replacement With Osteoarticular Allograft Prosthetic Composite in Failed Revision Total Elbow Arthroplasty With Marked Bone Loss.

Sailesh V Tummala, Kade S McQuivey, Nathaniel B Hinckley, Krista A Goulding, Kevin J Renfree,

Total elbow arthroplasty (TEA) procedures are becoming more prevalent with an associated increase in revision procedures. Revision TEA in the setting of marked bone loss poses a challenge for the treating surgeon. We present a viable surgical option for patients with extensive proximal humeral bone loss treated with proximal humerus ... Read more >>

Tech Hand Up Extrem Surg (Techniques in hand & upper extremity surgery)
[2021, :]

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The favorable donor site in microsurgery: Nerve and vein graft harvest from the dorsum of the foot.

Carina Wenzel, Eva Brix, Paul Heidekrueger, Daniel Lonic, Philip Lamby, Silvan M Klein, Alexandra Anker, Christian Taeger, Lukas Prantl, Andreas Kehrer,

<h4>Background and objective</h4>In complex hand traumas nerves and vessels are often destructed without the possibility for primary repair. For bridging defects of nerves, veins and arteries grafts are necessary. Commonly nerve and vein grafts from adjacent donor sites as the wrist, forearm or cubital region are harvested.<h4>Methods</h4>This study is a ... Read more >>

Clin Hemorheol Microcirc (Clinical hemorheology and microcirculation)
[2021, :]

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Hand-Assisted Laparoscopic Subtotal Colectomy for Ogilvie Syndrome Associated With Idiopathic Fibrosis of Colon After Simultaneous Pancreas Kidney Transplant.

Tsukasa Nakamura, Ryusuke Sugimoto, Shumpei Harada, Shuji Nobori, Hidetaka Ushigome, Mikiko Yoshikawa,

Ogilvie syndrome (acute colonic pseudo-obstruction) is a rare, acquired, life-threatening disorder for which treatment plans vary from simple observation to surgical intervention. Ogilvie syndrome has been reported in patients after renal or liver transplant, but its occurrence after simultaneous pancreas-kidney transplant is rare. Herein, we present the case of a ... Read more >>

Exp Clin Transplant (Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation)
[2021, :]

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Wrist fusion using an induced membrane technique for forearm salvage in a patient with an infected open injury with segmental bone loss: A case report

James M.Y. Chowdhury, Daniel J. Wilks, Waseem Bhat, Sam Vollans, Nicholas Foster, Jay Wiper, Paul J. Harwood,

This case report describes the management of a 27-year-old male who, after a quadbike accident, presented with an open, infected, segmental both bone forearm injury with significant bone and soft tissue loss including the radio-carpal joint. Limb salvage was accomplished in the form of a single bone forearm fusion utilising ... Read more >>

Trauma Case Rep (Trauma case reports)
[2021, 36:]

Cited: 0 times

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Long-term outcome of lymph vessel transplantation after chronic lymphorrhea.

Cecilia Dahlbäck, Rüdiger Baumeister, Magnus Åberg, Björn Arnljots, Lieselotte Frost Arner, Håkan Brorson,

A 52-year-old male patient developed a chronic fistula with excessive lymph leakage in the left axilla following removal of an enlarged lymph node with chronic local adipose tissue inflammation due to infection. After multiple surgeries, treatment with lymphatic vessel transplantation was successful. No recurrence occurred over 20 years of follow-up. ... Read more >>

Case Reports Plast Surg Hand Surg (Case reports in plastic surgery & hand surgery)
[2021, 8(1):169-174]

Cited: 0 times

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Outcomes of staged reconstruction of Zone 2 flexor tendon injuries in recent wide-awake surgical settings and an earlier case series.

Ahmed Fathy Sadek, Ahmed Sobhi Hweidi, Mohamed Atef Ahmed,

We report outcomes of patients who were managed with two-stage tendon grafting for neglected Zone 2 flexor tendon injuries from 2012 until 2019. The patients were divided into two cohorts: recent series (Series 1) included patients treated with local anaesthesia and epinephrine (16 fingers, from 2015), and earlier series (Series ... Read more >>

J Hand Surg Eur Vol (The Journal of hand surgery, European volume)
[2021, :17531934211053267]

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Carpometacarpal Arthrodesis for Traumatic Carpal Boss Among Combative Athletes.

Daniel B Polatsch, Robert M Zbeda, Steven Beldner, Charles P Melone,

Among professional combat athletes, excessive and repetitive trauma to the carpometacarpal (CMC) joints may cause instability, arthritis, and the development of traumatic carpal boss. If nonoperative management is unsuccessful, CMC joint arthrodesis with iliac crest bone graft and supplemental Kirschner wire fixation is a reliable surgical option that results in ... Read more >>

Orthopedics (Orthopedics)
[2021, :1-6]

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Osteoid Osteoma of the Distal Phalanx: A Rare Condition

Jimmy C Daher, Mohammad O Boushnak, Elie N Al Najjar, Esther H Tannoury, Ramzi C Moucharafieh,

Osteoid osteoma of the distal phalanges in the hand is rare and difficult to diagnose. We report a case of a 37-year-old Caucasian female patient who presented with a mass on the distal phalanx of the index finger. The patient was suffering from intermittent nocturnal pain for more than 18 months along ... Read more >>

Cureus (Cureus)
[0, 13(10):]

Cited: 0 times

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