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Fibromuscular Dysplasia

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Dissecting visceral fibromuscular dysplasia reveals a new vascular phenotype of the disease: a report from the ARCADIA-POL study.

Ewa Warchoł-Celińska, Krzysztof Pieluszczak, Marco Pappaccogli, Aleksandra Soplińska, Aleksander Prejbisz, Piotr Dobrowolski, Anna Klisiewicz, Jacek Kądziela, Aleksander Falkowski, Witold Śmigielski, Elżbieta Florczak, Katarzyna Jóźwik-Plebanek, Ilona Michałowska, Marek Kabat, Cezary Zgorzelski, Krzysztof Madej, Sławomir Nazarewski, Mikołaj Smólski, Łukasz Olewnik, Mieczysław Litwin, Małgorzata Szczerbo-Trojanowska, Krzysztof Zieniewicz, Wojciech Drygas, Olgierd Rowiński, Adam Witkowski, David Adlam, Patricia Van der Niepen, Alexandre Persu, Andrzej Januszewicz, Magdalena Januszewicz,

OBJECTIVE:Visceral artery fibromuscular dysplasia (VA FMD) manifestations range from asymptomatic to life-threatening. The aim of the study is to evaluate the prevalence and clinical characteristics of VA FMD. METHODS:A total of 232 FMD patients enrolled into ongoing ARCADIA-POL study were included in this analysis. All patients underwent detailed clinical evaluation ... Read more >>

J. Hypertens. (Journal of hypertension)
[2020, 38(4):737-744]

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Visceral artery fibromuscular dysplasia: another step in unravelling a mysterious vascular syndrome.

Daan J L van Twist,

J. Hypertens. (Journal of hypertension)
[2020, 38(4):605-607]

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Fibromuscular dysplasia and coronary artery fistula: links to pulmonary hypertension.

Wen Qian Zheng, Suchet Kumar, Mohammad El-Hajjar,

BMJ Case Rep (BMJ case reports)
[2020, 13(3):]

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Systematic and Multidisciplinary Evaluation of Fibromuscular Dysplasia Patients Reveals High Prevalence of Previously Undetected Fibromuscular Dysplasia Lesions and Affects Clinical Decisions: The ARCADIA-POL Study.

Ewa Warchol-Celinska, Aleksander Prejbisz, Piotr Dobrowolski, Anna Klisiewicz, Jacek Kadziela, Elzbieta Florczak, Ilona Michalowska, Katarzyna Jozwik-Plebanek, Marek Kabat, Pawel Kwiatek, Slawomir Nazarewski, Krzysztof Madej, Olgierd Rowinski, Lukasz Swiatlowski, Mariola Peczkowska, Katarzyna Hanus, Paulina Talarowska, Mikołaj Smolski, Katarzyna Kowalczyk, Iwona Kurkowska-Jastrzebska, Ludomir Stefanczyk, Andrzej Wiecek, Krystyna Widecka, Andrzej Tykarski, Lukasz Stryczynski, Mieczyslaw Litwin, Piotr Hoffman, Adam Witkowski, Malgorzata Szczerbo-Trojanowska, Magdalena Januszewicz, Andrzej Januszewicz,

Fibromuscular dysplasia (FMD), regarded as a generalized vascular disease, may affect all vascular beds and may result in arterial stenosis, occlusion, aneurysm, or dissection. It has been proposed to systematically evaluate all vascular beds in patients with FMD, regardless of initial FMD involvement. However, the impact of this approach on ... Read more >>

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2020, 75(4):1102-1109]

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Impact of percutaneous revascularization on left ventricular mass and its relationship to outcome in hypertensive patients with renal artery stenosis.

Yoshio Iwashima, Tetsuya Fukuda, Takeshi Horio, Hiroshi Kusunoki, Shin-Ichiro Hayashi, Kei Kamide, Yuhei Kawano, Toshihiko Ishimitsu, Fumiki Yoshihara,

BACKGROUND:We investigated the effects of percutaneous transluminal renal angioplasty on left ventricular (LV) mass, and the impact of LV mass reduction on outcomes. METHODS:A total of 144 hypertensive patients with renal artery stenosis (RAS) (mean age 69 years; 22.2% fibromuscular dysplasia [FMD]) who underwent angioplasty were included. Echocardiography was performed ... Read more >>

Am. J. Hypertens. (American journal of hypertension)
[2020, :]

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Fibromuscular dysplasia presenting with a deep vein thrombosis.

Danielle Lam, Shirley Jansen, Jonathan Tibballs, Andrew McLean-Tooke,

A 41-year-old male patient presented with isolated right lower limb swelling. An ultrasound scan showed right external iliac and femoral vein deep vein thrombosis due to extrinsic compression by an aneurysm of the right common iliac artery. Investigations including imaging and a tissue biopsy of right and left femoral arteries ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(2):]

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Brain-to-Pelvis Imaging Substantially Impacts Management of Patients With Fibromuscular Dysplasia.

Alexandre Persu, Heather L Gornik,

Hypertension (Hypertension (Dallas, Tex. : 1979))
[2020, 75(4):945-947]

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Efficacy of Antihypertensive Therapy in a Child with Unilateral Focal Fibromuscular Dysplasia of the Renal Artery: A Case Study and Review of Literature.

Ratna Acharya, Savannah Ellenwood, Kiran Upadhyay,

Background: Fibromuscular dysplasia (FMD) is one of the important etiologies of renovascular hypertension in children. It is usually resistant to multiple antihypertensive agents and can cause extreme elevation in blood pressures, which can lead to end organ damage if not promptly diagnosed and treated. Treatment options include medical management with ... Read more >>

Medicines (Basel) (Medicines (Basel, Switzerland))
[2020, 7(2):]

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[Bilateral renal infarction: A rare complication of fibromuscular dysplasia].

H M Villafuerte Ledesma, P Martín Azara, A Bartolomé Sánchez,

Bilateral renal infarction complicating Fibromuscular Dysplasia (FMD) is extremely rare and has so far been reported only in a handful of cases. We report a 44-year-old man who presented with complaints of abdominal pain and severe hypertension. Computed tomography of the abdomen revealed bilateral renal infarction and a renal angiography ... Read more >>

Hipertens Riesgo Vasc (Hipertension y riesgo vascular)
[2020, :]

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Coronary artery tortuosity: a narrative review.

Farima Kahe, Sadaf Sharfaei, Anmol Pitliya, Mehrian Jafarizade, Soroush Seifirad, Shaghayegh Habibi, Gerald Chi,

Coronary artery tortuosity (CAT) is a prevalent angiographic finding commonly associated with aging, hypertension, atherosclerosis and other conditions. Preliminary evidence suggests that degradation of elastin, a key component of extracellular matrix in the vascular wall, may be responsible for the development of CAT. The clinical significance of CAT should be ... Read more >>

Coron. Artery Dis. (Coronary artery disease)
[2020, 31(2):187-192]

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Isolated Renal Artery Dissection: A Systematic Review of Case Reports.

Anil Jha, Maxwell Afari, Ioannis Koulouridis, Tariq Bhat, Lawrence Garcia,

Isolated renal artery dissection (IRAD) is a rare and often unrecognized clinical entity, with a paucity of data on its epidemiology and management. We extracted 129 cases of IRAD from the medical literature between 1972 and 2016. IRAD as a result of an extended dissection from the aorta and splanchnic ... Read more >>

Cureus (Cureus)
[2020, 12(2):e6960]

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Intractable coronary fibromuscular dysplasia leading to end-stage heart failure and fatal heart transplantation.

Magdalena Maria Cattaneo, Marco Moccetti, Mattia Cattaneo, Daniel Sürder, Thomas Suter, Michele Martinelli, Eva Roost, Jürg Schmidli, Yara Banz, Carmen Schneiders, Giovanni Pedrazzini, Roberto Corti, Lorenz Räber, Filippo Crea, Paul Mohacsi, Augusto Gallino,

Coronary fibromuscular dysplasia is uncommon, and even rarer its unstable and recurrent course. We present the unique case of a 52-year-old woman who underwent in total 12 coronary angiographies and three percutaneous coronary intervention within 24 months because of repetitive acute coronary syndromes due to refractory spasm, dissection, restenosis all ... Read more >>

ESC Heart Fail (ESC heart failure)
[2020, :]

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A simple refined approach for renovascular hypertension in children: a ten-year experience.

Ken Saida, Koichi Kamei, Riku Hamada, Takahisa Yoshikawa, Yuji Kano, Hiroko Nagata, Mai Sato, Masao Ogura, Ryoko Harada, Hiroshi Hataya, Osamu Miyazaki, Shunsuke Nosaka, Shuichi Ito, Kenji Ishikura,

BACKGROUND:Despite advances in noninvasive vascular imaging, detection of renal artery stenosis via catheter angiography is the gold standard for the diagnosis of renovascular hypertension (RVH). Due to lack of evidence, the utility of various blood tests and imaging modalities remains unclear. METHODS:We retrospectively analyzed the utility of blood tests [plasma ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2020, :]

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Spontaneous Renal Artery Dissection in a Man with Previous Spontaneous Superior Mesenteric Artery Dissection.

Yujiro Yokoyama, Masato Nakajima,

Both spontaneous superior mesenteric artery dissection (SMAD) and spontaneous renal artery dissection (SRAD) are very rare conditions. Their etiologies and natural histories are not precisely defined, but they are thought to be associated with underlying conditions. In this report, we describe an extremely rare case of SRAD in a man ... Read more >>

Case Rep Vasc Med (Case reports in vascular medicine)
[2020, 2020:4726381]

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Detection of significant left renal artery stenosis caused by fibromuscular dysplasia with selective angiography.

Ramezan Jafari, Zohreh Rostami, Mohammad Nikpoor, Mohammad Javanbakht, Mohsen Sadeghi Ghahroudi, Mahbobeh Sadat Hosseini, Behzad Einollahi,

A 22-year-old female, was referred with a history of a headache and elevated blood pressure without family history of hypertension or familial dyslipidemia. Initially, a spiral computed tomographic angiography of the renal arteries was conducted, demonstrating completely abnormal left renal artery at the medial portion of the vessel with suspicious ... Read more >>

Arch Ital Urol Androl (Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica)
[2020, 91(4):269-271]

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Percutaneous transluminal angioplasty with selective stenting for the treatment of renal artery stenosis caused by fibromuscular dysplasia: 18 years' experience from the China Center for Cardiovascular Disease.

Yang Chen, Hui Dong, Xiongjing Jiang, Yu Deng, Yubao Zou, Wuqiang Che, Hongliang Xiong, Bo Xu, Yuejin Yang, Runlin Gao,

OBJECTIVES:This study aimed to evaluate the safety and efficiency of percutaneous transluminal angioplasty (PTA) with selective stenting treating Chinese patients with renal artery stenosis (RAS) due to fibromuscular dysplasia (FMD). BACKGROUND:Endovascular data of patients with RAS caused by FMD are scarce in China. METHODS:Clinical data of 105 hypertensive patients with ... Read more >>

Catheter Cardiovasc Interv (Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions)
[2020, 95 Suppl 1:641-647]

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Lung Transplantation for Bronchopulmonary Dysplasia in Adults: A Clinical and Pathologic Study of 3 Cases.

Natalia Liu, Oscar W Cummings, Amir Lagstein, Chadi A Hage, Kevin M Chan, Chen Zhang,

Bronchopulmonary dysplasia (BPD) is usually seen in premature infants who require mechanical ventilation and oxygen therapy for acute respiratory distress. Although most patients wean from oxygen therapy by the ages of 2 to 3, rehospitalization for respiratory problems is common in these patients in adulthood. There have been few studies ... Read more >>

Am. J. Surg. Pathol. (The American journal of surgical pathology)
[2020, 44(4):509-515]

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Natural course of incidentally detected isolated Celiac Artery Dissection with hepatic artery occlusion.

Chary Duraikannu, Parthasarathy Karunakaran, Shamim Ahamed Haithrous, Venkata Narasimha Kumar Pulupula,

Isolated celiac artery dissection (ICAD) is a rare entity with over 160 cases described in literature. We report a case of incidentally detected isolated celiac artery dissection during computed tomography evaluation for occult gastrointestinal bleeding. Though most cases of isolated celiac artery dissection are initially managed conservatively with antiplatelet and ... Read more >>

Radiol Case Rep (Radiology case reports)
[2020, 15(5):479-483]

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Red Dress Day in Croatia: stroke prevention based on sex differences.

Arijana Lovrenčić-Huzjan, Zdravka Poljaković,

Croat. Med. J. (Croatian Medical Journal)
[2020, 61(1):5-7]

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How to Repair Non-Atheromatous Carotid Lesions.

N M Bouayed, L A Bouziane,

Non-atheromatous surgical lesions are estimated to represent at most 10% of all carotid procedures, most of which involve atheromatous lesions. Isolated tortuosity of the carotid vessels is sometimes treated surgically. The pathologies most frequently studied are extra-cranial carotid aneurysms, dissections, and fibromuscular dysplasia. Behcet's disease only rarely affects the carotid ... Read more >>

Transl Med UniSa (Translational medicine @ UniSa)
[2020, 21:24-26]

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Renovascular Hypertension: Novel Insights.

Chrysoula Boutari, Eleni Georgianou, Alexandros Sachinidis, Alexandra Katsimardou, Konstantinos Christou, Alexia Piperidou, Asterios Karagiannis,

Renovascular hypertension (RVH) remains among the most prevalent and important, but also potentially reversible, causes of secondary hypertension. The predominant causes of renal artery stenosis (RAS) are atherosclerotic renovascular arterial stenosis (ARAS) and renal fibromuscular dysplasia. This condition can lead to progressive renal injury, cardiovascular complications and 'flash pulmonary edema'. ... Read more >>

Curr Hypertens Rev (Current hypertension reviews)
[2020, 16(1):24-29]

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A plasma proteogenomic signature for fibromuscular dysplasia.

Jeffrey W Olin, Antonio F Di Narzo, Valentina d'Escamard, Daniella Kadian-Dodov, Haoxiang Cheng, Adrien Georges, Annette King, Allison Thomas, Temo Barwari, Katherine C Michelis, Rihab Bouchareb, Emir Bander, Anelechi Anyanwu, Paul Stelzer, Farzan Filsoufi, Sander Florman, Mete Civelek, Stephanie Debette, Xavier Jeunemaitre, Johan L M Björkegren, Manuel Mayr, Nabila Bouatia-Naji, Ke Hao, Jason C Kovacic,

AIMS:Fibromuscular dysplasia (FMD) is a poorly understood disease that predominantly affects women during middle-life, with features that include stenosis, aneurysm, and dissection of medium-large arteries. Recently, plasma proteomics has emerged as an important means to understand cardiovascular diseases. Our objectives were: (i) to characterize plasma proteins and determine if any ... Read more >>

Cardiovasc. Res. (Cardiovascular research)
[2020, 116(1):63-77]

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Coronary artery disease and acute coronary syndrome in women.

Julinda Mehilli, Patrizia Presbitero,

There are important dissimilarities in clinical presentation, aggregation of comorbidities, cardiovascular risk factors and the quality of delivery of medical care among men and women with acute coronary syndrome (ACS). Compared with men, despite the well-known older age and more pronounced frailty, women with ACS present later from symptom onset ... Read more >>

Heart (Heart (British Cardiac Society))
[2020, 106(7):487-492]

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Diagnostically Challenging Case of Renal Artery Stenosis in a Pediatric Patient.

Osama Safdar, Fahad Alaifan, Sonds Alshammakh, Muatasaim Hakami, Daniyah F Alghaithi,

In this study we report a diagnostically challenging case of bilateral renal artery stenosis (RAS) in a nine-year-old boy presenting as uncontrolled hypertension (HTN). The objective of this clinical case report is to draw attention to the unlikely combination of a classical clinical presentation with several normal investigations. This is ... Read more >>

Cureus (Cureus)
[2020, 12(1):e6538]

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Unexpected presentation and surgical salvage of transplant renal artery dissection caused by vascular clamping: a case report.

Shunta Hori, Tatsuo Yoneda, Mitsuru Tomizawa, Kazuki Ichikawa, Yosuke Morizawa, Yasushi Nakai, Makito Miyake, Kiyohide Fujimoto,

BACKGROUND:Transplant renal artery dissection is a rare and serious event that can cause allograft dysfunction and activation of the renin-mediated renovascular hypertension. Most cases are induced by percutaneous transluminal angioplasty, arteriosclerotic disease, or fibromuscular dysplasia. We observed a case of transplant renal artery dissection induced by unusual causes during kidney ... Read more >>

BMC Nephrol (BMC nephrology)
[2020, 21(1):29]

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