Full Text Journal Articles about
Fetal Alcohol Syndrome

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Adult outcomes of childhood bronchiectasis.

Dawn Sibanda, Rosalyn Singleton, John Clark, Christine Desnoyers, Ellen Hodges, Gretchen Day, Gregory Redding,

Recent literature has highlighted the importance of transition from paediatric to adult care for children with chronic conditions. Non-cystic fibrosis bronchiectasis is an important cause of respiratory morbidity in low-income countries and in indigenous children from affluent countries; however, there is little information about adult outcomes of childhood bronchiectasis. We ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2020, 79(1):1731059]

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Maternal hypothermia from environmental exposure in the third trimester.

Margot Rosenthal, Vanessa Poliquin, Adelicia Yu,

A primigravida at 32 weeks gestation developed hypothermia after prolonged exposure to the elements at -30.0°C. Her core temperature dropped to 29.8°C with associated foetal bradycardia. Passive rewarming was undertaken with forced warm air blankets and warmed IV fluids. The foetal heart rate normalised once normothermia was achieved. Serial foetal ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2020, 79(1):1710894]

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Predicting the spread-risk potential of chronic wasting disease to sympatric ungulate species.

Catherine I Cullingham, Rhiannon M Peery, Anh Dao, Debbie I McKenzie, David W Coltman,

Wildlife disease incidence is increasing, resulting in negative impacts on the economy, biodiversity, and potentially human health. Chronic wasting disease (CWD) is a fatal, transmissible spongiform encephalopathy of cervids (wild and captive) which continues to spread geographically resulting in exposure to potential new host species. The disease agent (PrPCWD) is ... Read more >>

Prion (Prion)
[2020, 14(1):56-66]

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Altered Maternal Plasma Fatty Acid Composition by Alcohol Consumption and Smoking during Pregnancy and Associations with Fetal Alcohol Spectrum Disorders.

Krista D Sowell, Roberta R Holt, Janet Y Uriu-Adams, Christina D Chambers, Claire D Coles, Julie A Kable, Lyubov Yevtushok, Natalya Zymak-Zakutnya, Wladimir Wertelecki, Carl L Keen, ,

Objective: Polyunsaturated fatty acids are vital for optimal fetal neuronal development. The relationship between maternal alcohol consumption and smoking with third trimester plasma fatty acids were examined and their association with Fetal Alcohol Spectrum Disorders (FASD).Methods: Moderate to heavy alcohol-using and low/unexposed comparison women were recruited during mid-pregnancy from two ... Read more >>

J Am Coll Nutr (Journal of the American College of Nutrition)
[2020, :1-12]

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Sleep disturbance as a predictor of anxiety in children with Fetal Alcohol Spectrum Disorders and typically developing children.

Rabya Mughal, Anna Joyce, Catherine Hill, Dagmara Dimitriou,

BACKGROUND:High levels of anxiety and sleep problems are common features of Fetal Alcohol Spectrum Disorders (FASD). The strong association between sleep and anxiety has been documented in typically developing (TD) populations and is thought to be bidirectional. The association between sleep and anxiety in children with FASD has not yet ... Read more >>

Res Dev Disabil (Research in developmental disabilities)
[2020, 101:103610]

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Incontinence in persons with fetal alcohol spectrum disorders: a polish cohort.

Sylvia Roozen, Katarzyna Anna Dylag, Katarzyna Przybyszewska, Justine Niemczyk, Alexander von Gontard, Gjalt-Jorn Ygram Peters, Gerjo Kok, Leopold Curfs,

INTRODUCTION:Fetal alcohol spectrum disorders (FASD) is an important preventable public health concern, associated to a number of common pediatric problems such as incontinence. Little is known about the prevalence and presentation of incontinence in FASD, which hinders effective management. OBJECTIVE:The aim of the present study was to investigate incontinence among people ... Read more >>

J Pediatr Urol (Journal of pediatric urology)
[2020, :]

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Early ethanol exposure inhibits the differentiation of hippocampal dentate gyrus granule cells in a mouse model of Fetal Alcohol Spectrum Disorders.

Wenhua Xu, Hui Li, Caigu He, Jacqueline Frank, Gang Chen,

BACKGROUND:Alcohol consumption during pregnancy may damage the developing central nervous system of the fetus and lead to brain structural and functional deficits in the children, known as Fetal Alcohol Spectrum Disorders. The underlying mechanisms have not been fully elucidated. Previously using a third trimester-equivalent mouse model, ethanol-induced behavioral deficits (including spatial ... Read more >>

Alcohol. Clin. Exp. Res. (Alcoholism, clinical and experimental research)
[2020, :]

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Increased Notching of the Corpus Callosum in Fetal Alcohol Spectrum Disorder: A Callosal Misunderstanding?

E Schneble, C Lack, M Zapadka, C M Pfeifer, D M E Bardo, J Cagley, J Acharya, A P Klein, M Balla, J T Obayashi, D Ross, D R Pettersson, J M Pollock,

BACKGROUND AND PURPOSE:In the medicolegal literature, notching of the corpus callosum has been reported to be associated with fetal alcohol spectrum disorders. Our purpose was to analyze the prevalence of notching of the corpus callosum in a fetal alcohol spectrum disorders group and a healthy population to determine whether notching ... Read more >>

AJNR Am J Neuroradiol (AJNR. American journal of neuroradiology)
[2020, :]

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Characterizing Alcohol-Related Neurodevelopmental Disorder (ARND): Prenatal Alcohol Exposure and the Spectrum of Outcomes.

Claire D Coles, Wendy Kalberg, Julie A Kable, Barbara Tabachnick, Philip A May, Christina D Chambers,

BACKGROUND:Effects of prenatal alcohol exposure (PAE) are conceptualized as fetal alcohol spectrum disorder (FASD), with fetal alcohol syndrome (FAS) as the most severe. Many find it more difficult to characterize behavioral and cognitive effects of exposure on the central nervous system when physical signs are not present. In the current ... Read more >>

Alcohol. Clin. Exp. Res. (Alcoholism, clinical and experimental research)
[2020, :]

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Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish.

Suelen Baggio, Kamila Zenki, Alberto Martins Silva, Thainá Garbino Dos Santos, Giovana Rech, Gabriela Lazzarotto, Renato Dutra Dias, Ben Hur Mussulini, Eduardo Pacheco Rico, Diogo Losch de Oliveira,

Fetal alcohol spectrum disorders (FASD) describe a wide range of ethanol-induced developmental disabilities, including craniofacial dysmorphology, and neurochemical and behavioral impairments. Zebrafish has become a popular animal model to evaluate the long-lasting effects of, both, severe and milder forms of FASD, including alterations to neurotransmission. Glutamate is one of the ... Read more >>

Neurotoxicology (Neurotoxicology)
[2020, 78:152-160]

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Postnatal Ethanol Exposure Activates HDAC-Mediated Histone Deacetylation, Impairs Synaptic Plasticity Gene Expression and Behavior in Mice.

Madhu Shivakumar, Shivakumar Subbanna, Vikram Joshi, Balapal S Basavarajappa,

BACKGROUND:Alcohol consumption during pregnancy is widespread and contributes to pediatric neurological defects including hippocampal and neocortex dysfunction, causing cognitive deficits termed fetal alcohol spectrum disorders (FASDs). However, the critical mechanisms underlying these brain abnormalities remain poorly described. METHODS:Using a postnatal ethanol exposure (PEE) animal model and pharmacological, epigenetic, synaptic plasticity-related ... Read more >>

Int. J. Neuropsychopharmacol. (International Journal of Neuropsychopharmacology)
[2020, :]

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Graded Cerebellar Lobular Volume Deficits in Adolescents and Young Adults with Fetal Alcohol Spectrum Disorders (FASD).

Edith V Sullivan, Eileen M Moore, Barton Lane, Kilian M Pohl, Edward P Riley, Adolf Pfefferbaum,

The extensive prenatal developmental growth period of the cerebellum renders it vulnerable to unhealthy environmental agents, especially alcohol. Fetal alcohol spectrum disorders (FASD) is marked by neurodysmorphology including cerebral and cerebellar volume deficits, but the cerebellar lobular deficit profile has not been delineated. Legacy MRI data of 114 affected and ... Read more >>

Cereb. Cortex (Cerebral cortex (New York, N.Y. : 1991))
[2020, :]

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Reduced Hippocampal Volumes Partially Mediate Effects of Prenatal Alcohol Exposure on Spatial Navigation on a Virtual Water Maze Task in Children.

Neil C Dodge, Kevin G F Thomas, Ernesta M Meintjes, Christopher D Molteno, Joseph L Jacobson, Sandra W Jacobson,

BACKGROUND:Prenatal alcohol exposure (PAE) has been linked to poorer performance on the Morris water maze (MWM), a test of spatial navigation in rodents that is dependent on hippocampal functioning. We recently confirmed these findings in children with PAE on a human analog of the MWM, the virtual water maze (VWM). ... Read more >>

Alcohol. Clin. Exp. Res. (Alcoholism, clinical and experimental research)
[2020, :]

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Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.

Jeffrey R Wozniak, Birgit A Fink, Anita J Fuglestad, Judith K Eckerle, Christopher J Boys, Kristin E Sandness, Joshua P Radke, Neely C Miller, Christopher Lindgren, Ann M Brearley, Steven H Zeisel, Michael K Georgieff,

BACKGROUND:Despite the high prevalence of fetal alcohol spectrum disorder (FASD), there are few interventions targeting its core neurocognitive and behavioral deficits. FASD is often conceptualized as static and permanent, but interventions that capitalize on brain plasticity and critical developmental windows are emerging. We present a long-term follow-up study evaluating the ... Read more >>

J Neurodev Disord (Journal of neurodevelopmental disorders)
[2020, 12(1):9]

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Dermatoglyphic fluctuating asymmetry and total a-b ridge count as biomarkers of Foetal Alcohol Syndrome: Analysis in children adopted from Eastern Europe.

Vicente Andreu-Fernández, Sabina Planas, Elisabet Navarro-Tapia, Araceli Rosa, Oscar García-Algar,

BACKGROUND:Dermatoglyphics, formed mainly during the second trimester of pregnancy have been used as markers of developmental disturbances. The aim of this study was to examine if dermatoglyphic variation in children adopted from Eastern European countries with differential prenatal alcohol exposure, could be associated with diagnosis of Foetal Alcohol Spectrum Disorder ... Read more >>

Early Hum. Dev. (Early human development)
[2020, 143:104999]

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Fetal alcohol spectrum disorders awareness in health professionals: implications for psychiatry.

Marisa Patrizia Messina, Alessio D'Angelo, Gemma Battagliese, Giovanna Coriale, Luigi Tarani, Simona Pichini, Debora Rasio, Giovanni Parlapiano, Marco Fiore, Carla Petrella, Mario Vitali, Giampiero Ferraguti, Mauro Ceccanti, ,

Fetal Alcohol Spectrum Disorders (FASD) are a plethora of malformative conditions leading to mental retardation that affect newborns and children who have been exposed to alcohol during pregnancy or breastfeeding. FASD is a relevant topic for public health in Europe: European area is first in ranking for alcohol use during ... Read more >>

Riv Psichiatr (Rivista di psichiatria)
[2020, 55(2):79-89]

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Alcohol use in pregnancy and its impact on the mother and child.

Ju Lee Oei,

Prenatal alcohol exposure is one of the most important causes of preventable cognitive impairment in the world. The developing neurological system is exquisitely sensitive to harm from alcohol and there is now also substantial evidence that alcohol-related harm can extend beyond the individual person, leading to epigenetic changes and intergenerational ... Read more >>

Addiction (Addiction (Abingdon, England))
[2020, :]

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Fetal Alcohol Spectrum Disorders: Health Needs Assessment in Brazil.

Anastácia Guimarães Rocha, Paulo Ricardo Assis de Souza, Gabriela Elis Wachholz, Lucas Rosa Fraga, Maria Teresa V Sanseverino, Anna Pires Terra, André Anjos da Silva, Fernanda Sales Luiz Vianna, Alberto Mantovani Abeche, Mariela Larrandaburu, Miguel Del Campo, Lavínia Schuler-Faccini,

BACKGROUND:Fetal alcohol syndrome (FAS) is a disorder caused by alterations in embryo-fetal development due to prenatal alcohol exposure. It is estimated that between 0.5 and 2 per 1,000 individuals are born with FAS every year. In Brazil, there are few studies addressing the extent of the problem of FAS/fetal alcohol ... Read more >>

Alcohol. Clin. Exp. Res. (Alcoholism, clinical and experimental research)
[2020, 44(3):660-668]

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Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders.

Shahid Mohammad, Stephen J Page, Li Wang, Seiji Ishii, Peijun Li, Toru Sasaki, Aiesha Basha, Anna Salzberg, Zenaide Quezado, Fumiaki Imamura, Hirotaka Nishi, Keiichi Isaka, Joshua G Corbin, Judy S Liu, Yuka Imamura Kawasawa, Masaaki Torii, Kazue Hashimoto-Torii,

Learning disabilities are hallmarks of congenital conditions caused by prenatal exposure to harmful agents. These include fetal alcohol spectrum disorders (FASDs) with a wide range of cognitive deficiencies, including impaired motor skill development. Although these effects have been well characterized, the molecular effects that bring about these behavioral consequences remain ... Read more >>

Nat. Neurosci. (Nature neuroscience)
[2020, :]

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Proceedings of the 2019 Annual Meeting of the Fetal Alcohol Spectrum Disorders Study Group.

Derek A Hamilton, Sandra M Mooney, Christie L M Petrenko, Kristin M Hamre,

The 2019 Fetal Alcohol Spectrum Disorders Study Group (FASDSG) meeting was entitled "Computational Approaches to Studying Behavioral Control and Individual Change." The theme was reflected in the presentations of two keynote speakers: A. David Redish, Ph.D. who spoke about computational psychiatry and vulnerabilities in decision-making processes, and Kevin Grimm, Ph.D. ... Read more >>

Alcohol (Alcohol (Fayetteville, N.Y.))
[2020, :]

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Prevalence and patterns of sensory processing behaviors in a large clinical sample of children with prenatal alcohol exposure.

Tracy L Jirikowic, John C Thorne, Susan A McLaughlin, Tiffany Waddington, Adrian K C Lee, Susan J Astley Hemingway,

BACKGROUND:Atypical behavioral responses to sensation are reported in a large proportion of children affected by prenatal alcohol exposure (PAE). Systematic examination of symptoms across the fetal alcohol spectrum in a large clinical sample is needed to inform diagnosis and intervention. AIMS:To describe the prevalence and patterns of atypical sensory processing ... Read more >>

Res Dev Disabil (Research in developmental disabilities)
[2020, 100:103617]

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18q12.3-q21.1 microdeletion detected in the prenatally alcohol-exposed dizygotic twin with discordant fetal alcohol syndrome phenotype.

Hanna Kahila, Heidi Marjonen, Pauliina Auvinen, Kristiina Avela, Raili Riikonen, Nina Kaminen-Ahola,

BACKGROUND:A pair of dizygotic twins discordantly affected by heavy prenatal alcohol exposure (PAE) was reported previously by Riikonen, suggesting the role of genetic risk or protective factors in the etiology of alcohol-induced developmental disorders. Now, we have re-examined these 25-year-old twins and explored genetic origin of the phenotypic discordancy reminiscent ... Read more >>

Mol Genet Genomic Med (Molecular genetics & genomic medicine)
[2020, :e1192]

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Hypertension and Reproduction.

Peter M Nilsson, Margus Viigimaa, Aleksander Giwercman, Renata Cifkova,

PURPOSE OF REVIEW:Many aspects of reproduction have been associated with increased blood pressure and impaired glucose metabolism that reveals a subsequent increased risk of cardiovascular disease. The aim of this review is to assess reproductive life factors associated with an increased risk of hypertension and cardiovascular disease, e.g., early life ... Read more >>

Curr. Hypertens. Rep. (Current hypertension reports)
[2020, 22(4):29]

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Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Life-Style Habits.

Mohammad Danesh-Shakiba, Jalal Poorolajal, Pedram Alirezaei,

Purpose:The association of androgenetic alopecia (AGA) with cardiovascular risk factors including hypertension, smoking and high body mass index (BMI) has been investigated in several studies. However, the results are discrepant. The aim of the present study was to evaluate the association of AGA with anthropometrics, blood pressure and lifestyle habits. ... Read more >>

Clin Cosmet Investig Dermatol (Clinical, cosmetic and investigational dermatology)
[2020, 13:137-143]

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Moderate prenatal alcohol exposure impairs cognitive control, but not attention, on a rodent touchscreen continuous performance task.

Sarah L Olguin, Shannon M Thompson, Jared W Young, Jonathan L Brigman,

A common feature associated with fetal alcohol spectrum disorders is the inability to concentrate on a specific task while ignoring distractions. Human continuous performance tasks (CPT), measure vigilance and cognitive control simultaneously while these processes are traditionally measured separately in rodents. We recently established a touchscreen 5-choice CPT (5C-CPT) that ... Read more >>

Genes Brain Behav. (Genes, brain, and behavior)
[2020, :e12652]

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