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Full Text Journal Articles about
Emphysema

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miR-200b regulates cellular senescence and inflammatory responses by targeting ZEB2 in pulmonary emphysema.

Zhiming Shen, Wenting Xuan, Huanhuan Wang, Fei Sun, Chengxin Zhang, Qian Gong, Shenglin Ge,

Smoking is an important factor in the pathogenesis of chronic obstructive pulmonary disease (COPD), which is commonly characterised by cellular senescence and inflammation. Recently, miR-200b has emerged as an important target to cure lung disease; however, the function of miR-200b in reducing cellular senescence and inflammatory responses has not been ... Read more >>

Artif Cells Nanomed Biotechnol (Artificial cells, nanomedicine, and biotechnology)
[2020, 48(1):656-663]

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Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats.

Zhouxin Ren, Jiansheng Li, Junling Shen, Haibin Yu, Xiaofeng Mei, Peng Zhao, Zhenya Xiao, Wanliu Wu,

Context: Clinical reports showed sildenafil beneficial therapy on severe chronic obstructive pulmonary disease (COPD) with pulmonary hypertension (PH) patients.Objective: The study investigated therapeutic effects of silenafil on pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats.Materials and methods: Female Sprague-Dawley rats (200-250 g) were divided into control group ... Read more >>

Pharm Biol (Pharmaceutical biology)
[2020, 58(1):116-123]

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Recognition and Management of Subcutaneous Emphysema as a Complication of Robotic-Assisted Laparoscopic Surgery: A Case Report.

Thomas J Pallaria, Michael McLaughlin, Lauren Diskerud,

This case report discusses an unlikely occurrence of massive subcutaneous emphysema in an elective robotic-assisted laparoscopic total hysterectomy in a 45-year-old, ASA class 1 woman. The patient's perioperative course was otherwise uncomplicated, with the subcutaneous emphysema developing at surgical closure. The patient presented with substantial crepitus spanning from her face ... Read more >>

AANA J (AANA journal)
[2020, 88(2):131-134]

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Pulmonary high-grade fetal adenocarcinoma associated with cystic airspace: A case report.

Hironori Ishida, Masanori Yasuda, Hiroyuki Nitanda, Akitoshi Yanagihara, Ryo Taguchi, Ryuichi Yoshimura, Tetsuya Umesaki, Hirozo Sakaguchi, Yoshihiko Shimizu,

Lung cancers associated with cystic airspaces have a life-threatening risk of a missed or delayed diagnosis. Here, we report a case of pulmonary high-grade fetal adenocarcinoma, a rare lung carcinoma associated with cystic airspaces, as confirmed by computed tomography (CT) scan. A 73-year-old asymptomatic male with a 52-pack a year ... Read more >>

Thorac Cancer (Thoracic cancer)
[2020, :]

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Amelioration of elastase-induced lung emphysema and reversal of pulmonary hypertension by pharmacological iNOS inhibition in mice.

Athanasios Fysikopoulos, Michael Seimetz, Stefan Hadzic, Fenja Knoepp, Cheng-Yu Wu, Kathrin Malkmus, Jochen Wilhelm, Alexandra Pichl, Mariola Bednorz, Elsa Tadele Roxlau, Hossein A Ghofrani, Natascha Sommer, Mareike Gierhardt, Ralph T Schermuly, Werner Seeger, Friedrich Grimminger, Norbert Weissmann, Simone Kraut,

BACKGROUND AND PURPOSE:Chronic obstructive pulmonary disease (COPD), encompassing chronic airway obstruction and lung emphysema, is a major worldwide health problem and a severe socio-economic burden. Evidence previously provided by our group has shown that inhibition of inducible nitric oxide synthase (iNOS) prevents development of mild emphysema in a mouse model ... Read more >>

Br. J. Pharmacol. (British Journal of Pharmacology)
[2020, :]

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Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia.

Ruihong Sun, Hongyuan Liu, Xiang Wang,

The coronavirus disease 2019 (COVID-19) pneumonia is a recent outbreak in mainland China and has rapidly spread to multiple countries worldwide. Pulmonary parenchymal opacities are often observed during chest radiography. Currently, few cases have reported the complications of severe COVID-19 pneumonia. We report a case where serial follow-up chest computed ... Read more >>

Korean J Radiol (Korean journal of radiology)
[2020, :]

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Risk factors associated with the detection of pulmonary emphysema in older asymptomatic respiratory subjects

Ivette Buendia-Roldan, Alexia Palma-Lopez, Danaireth Chan-Padilla, Iliana Herrera, Mariel Maldonado, Rosario Fernandez-Plata, David Martinez-Briseño, Mayra Mejia, Moises Selman,

<title>Abstract</title> <p> Background: Several lung structural and functional abnormalities may occur associated withaging, including emphysema. In this study, we evaluated the frequency and risk factors associated with emphysema in respiratory asymptomatic individuals enrolled in our Lung Aging Program. From a cohort of 687 subjects, we found by high-resolution ... Read more >>

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Spontaneous Pneumomediastinum and Diffuse Subcutaneous Emphysema after Methamphetamine Inhalation.

Michael Agustin, Gabriel David, Ji Yeong Kang, Ornusa Teerasukjinda,

Methamphetamines are commonly abused drugs for their stimulant and euphoric effects. Inhaled and intravenous use may cause damage to the respiratory system. Spontaneous pneumomediastinum is a condition where changes in intrathoracic pressure leads to alveolar rupture and dissection of air along the tracheobronchial tree. Massive subcutaneous emphysema may result from ... Read more >>

Case Rep Pulmonol (Case reports in pulmonology)
[2020, 2020:7538748]

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Paired CT Measures of Emphysema and Small Airways Disease and Lung Function and Exercise Capacity in Smokers with Radiographic Bronchiectasis.

Carlos H Martinez, Yuka Okajima, Andrew Yen, Diego J Maselli, Pietro Nardelli, Farbord Rahaghi, Kendra Young, Gregory Kinney, Charles Hatt, Craig Galban, George R Washko, MeiLan Han, Raúl San José Estépar, Alejandro A Diaz,

RATIONALE AND OBJECTIVES:Bronchiectasis (BE) is associated with chronic obstructive pulmonary disease (COPD), but emphysema and small airways disease, main pathologic features of COPD, have been sparsely studied in BE. We aimed to objectively assess those features in smokers with and without radiographic BE and examine its relationships to airflow obstruction ... Read more >>

Acad Radiol (Academic radiology)
[2020, :]

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Subcutaneous emphysema as a complication of the use of a laryngeal mask in a child.

S Marinho, P Frias, I Oliveira, R Silva, F Rodrigues, A Paiva,

The use of supraglottic airway devices has been increasing in popularity, mostly due to their high success rate and low complications. However, there is very little information available about the potential and group specific concerns regarding their use in children. We present the first description of a child that developed ... Read more >>

Rev Esp Anestesiol Reanim (Revista espanola de anestesiologia y reanimacion)
[2020, :]

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ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice.

Shoji Suzuki, Makoto Ishii, Takanori Asakura, Ho Namkoong, Satoshi Okamori, Kazuma Yagi, Hirofumi Kamata, Tatsuya Kusumoto, Shizuko Kagawa, Ahmed E Hegab, Masaki Yoda, Keisuke Horiuchi, Naoki Hasegawa, Tomoko Betsuyaku,

Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease and is associated with chronic pulmonary inflammation caused by cigarette smoking, with contributions from immune cells such as neutrophils, macrophages, and lymphocytes. Although matrix metalloproteinases are well-known to contribute to emphysema progression, the role of a disintegrin and metalloproteinase ... Read more >>

Am. J. Physiol. Lung Cell Mol. Physiol. (American journal of physiology. Lung cellular and molecular physiology)
[2020, :]

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Development of a tension pneumomediastinum during mechanical ventilation of a young Irish Wolfhound.

Kristin M Zersen, Jenica L Haraschak, Lauren A Sullivan,

OBJECTIVE:To report the development of a tension pneumomediastinum during mechanical ventilation of a young Irish Wolfhound with aspiration pneumonia. CASE SUMMARY:A 9-month-old intact female Irish Wolfhound was presented for clinical signs consistent with aspiration pneumonia. Evaluation of her pedigree and clinical signs prompted suspicion of Irish Wolfhound rhinitis bronchopneumonia syndrome ... Read more >>

J Vet Emerg Crit Care (San Antonio) (Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001))
[2020, :]

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Periorbital Emphysema Presenting With Diplopia After Rhinoplasty.

Ho Yun Lee, Jun Lee, Myoung Su Choi, Su Jin Kim,

Periorbital emphysema is a well-known but very rare complication after rhinoplasty. Here, we present a case of periorbital emphysema presenting with diplopia and eyeball deviation after rhinoplasty. All symptoms disappeared spontaneously within days, without any complications. ... Read more >>

J Craniofac Surg (The Journal of craniofacial surgery)
[2020, :]

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Subcutaneous emphysema and hypercarbia as a complication of laparoscopic procedure: case report.

Sadal K Aldakhil, Abeer A Tashkandi, Mohammed K Al Harbi, Adel Al Shehri,

Subcutaneous emphysema (SE) is a rare complication of laparoscopic procedures, with an incidence rate of only 0.43-2.3%. In this report, we present a case of a 28-year-old male who underwent an elective laparoscopic inguinal hernia repair and developed surgical emphysema, hypercarbia and respiratory acidosis intraoperatively. Based on our findings, we ... Read more >>

J Surg Case Rep (Journal of Surgical Case Reports)
[2020, 2020(3):rjz415]

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Blunt laryngeal trauma presenting as bilateral massive pneumothoraces and subcutaneous emphysema: a multidisciplinary approach to management.

Christopher W Noel, Suneel Kumar Pooboni, Gamal Metwalli Metwalli, Safeena Kherani,

A 3-year-old boy had an unwitnessed fall from a highchair. The child had no loss of consciousness, vomiting, stridor or respiratory distress but within a few minutes had significant swelling in the neck, scalp and around the eyes. He was brought immediately to the emergency room where he deteriorated rapidly ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(3):]

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The added value of postmortem magnetic resonance imaging in cases of hanging compared to postmortem computed tomography and autopsy.

Eva Deininger-Czermak, Jakob Heimer, Carlo Tappero, Michael J Thali, Dominic Gascho,

The purpose of this study was to evaluate the added value of postmortem magnetic resonance imaging (MRI) compared to postmortem computed tomography (CT) and autopsy in cases of fatal hanging. In addition, the study analyzed the strengths of each examination method regarding typical injuries in these cases. We investigated a ... Read more >>

Forensic Sci Med Pathol (Forensic science, medicine, and pathology)
[2020, :]

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A rare case report: Cervical subcutaneous and mediastinal emphysema due to mastoid fracture.

Haydar Gök, Selim Şeker, Halil Olgun Peker, Mehmet Alpay Çal, Tamer Altay, Suat Çelik,

Subcutaneous emphysema occurs when air enters the soft tissue, which usually appears in the soft tissues of the chest wall or neck. It may also arise from pneumothorax or skin lacerations after trauma or other reasons. Mediastinal emphysema may be either associated with subcutaneous emphysema or seen alone. The air ... Read more >>

Ulus Travma Acil Cerrahi Derg (Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES)
[2020, 26(2):328-330]

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Iatrogenic post-pulpectomy cervicofacial subcutaneous emphysema in a paediatric patient.

Vir Singh, Latha Ganti, Joshua D Haupt, Bruce Marshall,

BMJ Case Rep (BMJ case reports)
[2020, 13(3):]

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Comparison of Artificial Intelligence-Based Fully Automatic Chest CT Emphysema Quantification to Pulmonary Function Testing.

Andreas M Fischer, Akos Varga-Szemes, Marly van Assen, L Parkwood Griffith, Pooyan Sahbaee, Jonathan I Sperl, John W Nance, U Joseph Schoepf,

OBJECTIVE. The purpose of this study was to evaluate an artificial intelligence (AI)-based prototype algorithm for fully automated quantification of emphysema on chest CT compared with pulmonary function testing (spirometry). MATERIALS AND METHODS. A total of 141 patients (72 women, mean age ± SD of 66.46 ± 9.7 years [range, ... Read more >>

AJR Am J Roentgenol (AJR. American journal of roentgenology)
[2020, :1-7]

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Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in COPD.

Kiyoshi Uemasu, Naoya Tanabe, Kazuya Tanimura, Koichi Hasegawa, Tatsushi Mizutani, Yoko Hamakawa, Susumu Sato, Emiko Ogawa, Matthew J Thomas, Machiko Ikegami, Shigeo Muro, Toyohiro Hirai, Atsuyasu Sato,

Epithelial dysfunction in the small airways may cause the development of emphysema in chronic obstructive pulmonary disease. CCAAT/enhancer binding protein-α (C/EBPα), a transcription factor, is required for lung maturation during development and is also important for lung homeostasis after birth, including the maintenance of serine protease/antiprotease balance in the bronchiolar ... Read more >>

Am. J. Respir. Cell Mol. Biol. (American journal of respiratory cell and molecular biology)
[2020, :]

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The STELVIO trial, a game changer for bronchoscopic lung volume reduction in patients with severe emphysema.

Rein Posthuma, Lowie E G W Vanfleteren,

The STELVIO trial was crucial to ensure that bronchoscopic lung volume reduction using one-way valves has evolved from an experimental intervention into a state-of-the-art treatment option for specific patients with advanced emphysema http://bit.ly/2IgMrsp. ... Read more >>

Breathe (Sheff) (Breathe (Sheffield, England))
[2020, 16(1):200004]

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Management of extensive subcutaneous emphysema using negative pressure wound therapy dressings.

Nai-Chien Huan, Noorasyikin Mohamed Arifin, Teng-Shin Khoo, Yean-Chen Lai,

Subcutaneous emphysema (SE) is a common but usually self-limiting complication of cardiothoracic procedures. Rarely, it can be life threatening and is characterized by extensive cutaneous tension and airway compromise requiring immediate intervention. There is a paucity of data on the most efficacious treatment methods for extensive SE. We report an ... Read more >>

Respirol Case Rep (Respirology case reports)
[2020, 8(3):e00544]

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Recurrent Pneumomediastinum Treated With Endobronchial Valve Placement After Source Detection by Bilateral Medical Thoracoscopy.

Arjan S Flora, Alejandro A Aragaki-Nakahodo, Sadia Benzaquen,

J Bronchology Interv Pulmonol (Journal of bronchology & interventional pulmonology)
[2020, 27(2):e24-e27]

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Pneumothorax, pneumomediastinum, and dysphonia complicating awake transcarotid artery revascularization.

Ross M Clark, John A Curci,

A 59-year-old woman presented with advanced, symptomatic carotid artery stenosis in the setting of severe medical comorbidities including coronary artery disease, congestive heart failure with recent admission for exacerbation, and diabetes mellitus. She underwent awake transcarotid artery revascularization because of her medically high-risk status. Postoperatively, she was noted to have ... Read more >>

J Vasc Surg Cases Innov Tech (Journal of vascular surgery cases and innovative techniques)
[2020, 6(1):133-135]

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Alpha-1 Antitrypsin Mutations: Is One Too Many?

Andrew J Sandford,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 201(5):505-506]

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