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Electroconvulsive Therapy

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Electroconvulsive Therapy versus Fluoxetine in Suicidal Resolution for Patients With Major Depressive Disorder.

Ching-Hua Lin, Cheng-Chung Chen, Chun-Jen Huang,

OBJECTIVE:Resolution of suicidal ideation for patients with major depressive disorder is an important public health challenge. We aimed to determine whether electroconvulsive therapy (ECT) or fluoxetine was more efficacious in resolving suicidal ideation and achieving long-term protective effect against suicidality. METHODS:The data used in this study were drawn from 2 ... Read more >>

J ECT (The journal of ECT)
[2020, :]

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Genetic determinants of circulating VEGF levels in major depressive disorder and electroconvulsive therapy response.

Elisabetta Maffioletti, Massimo Gennarelli, Chiara Magri, Luisella Bocchio-Chiavetto, Marco Bortolomasi, Cristian Bonvicini, Maria Abate, Luigi Trabucchi, Sheila Ulivi, Alessandra Minelli,

Alterations in peripheral vascular endothelial growth factor (VEGF) levels were observed in major depressive disorder and relative treatments and were shown to be influenced by genetic variants. The study objective was to explore, at a genome-wide level, possible interplaying effects between the genetic background and major depressive disorder in regulating ... Read more >>

Drug Dev. Res. (Drug development research)
[2020, :]

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Effects of Electroconvulsive Therapy on Short-Term Suicide Mortality in a Risk-Matched Patient Population.

Talya Peltzman, Brian Shiner, Bradley V Watts,

OBJECTIVE:Although evidence has suggested that electroconvulsive therapy (ECT) is effective in reducing suicidal ideation, research establishing the effectiveness of ECT in reducing short-term risk of death by suicide is less conclusive. This study assessed whether receipt of ECT reduced suicide mortality among patients seeking healthcare in Veterans Health Administration hospitals. ... Read more >>

J ECT (The journal of ECT)
[2020, :]

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Electroconvulsive Therapy in Italy-Current Dissemination of Treatment and Determining Factors of the Past.

Saskia Wilhelmy, Michael Grözinger, Dominik Groß, Andreas Conca,

OBJECTIVES:The history of electroconvulsive therapy (ECT) spans eight decades, over which period this method of treatment has been modernized. At the same time, however, the conflict between acceptance and rejection of ECT therapy remains unresolved today. This ambivalence is particularly noticeable in Italy, where the number of uses of ECT ... Read more >>

J ECT (The journal of ECT)
[2020, :]

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The Incidence of Post-Electroconvulsive Therapy Headache: A Systematic Review.

Laura Aleida Christina Mulder, Koen Pieter Grootens,

Headache is a common side effect of electroconvulsive therapy (ECT), but reports on its incidence vary widely. A broad array of treatment regimens have been proposed in the literature. The pathophysiology of post-ECT headache is unclear but a vascular origin has been suggested. A systematic literature search was executed in ... Read more >>

J ECT (The journal of ECT)
[2020, :]

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Changes in White Matter Microstructure After Electroconvulsive Therapy for Treatment-Resistant Depression.

Gregor Gryglewski, René Seiger, Pia Baldinger-Melich, Jakob Unterholzner, Benjamin Spurny, Thomas Vanicek, Andreas Hahn, Siegfried Kasper, Richard Frey, Rupert Lanzenberger,

BACKGROUND:Treatment-resistant depression is among the most debilitating conditions in psychiatry. Recent studies have associated alterations in white matter microstructure measured with magnetic resonance imaging with poor antidepressant response. Therefore, the extent to which electroconvulsive therapy, the most effective therapeutic option for treatment-resistant depression, affects white matter microstructure warrants investigation. METHODS:A ... Read more >>

Int. J. Neuropsychopharmacol. (International Journal of Neuropsychopharmacology)
[2020, 23(1):20-25]

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Repeated Sugammadex Administration in a Catatonic Patient for Electroconvulsive Therapy.

Predrag Gligorovic, Jacob Matthews,

J ECT (The journal of ECT)
[2020, :]

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Long-term subjective memory after electroconvulsive therapy.

Robert Sigström, Axel Nordenskjöld, Anders Juréus, Caitlin Clements, Erik Joas, Erik Pålsson, Mikael Landén,

BACKGROUND:There have been reports of long-term subjective memory worsening after electroconvulsive therapy (ECT). AIMS:To study the prevalence and risk factors of long-term subjective memory worsening among patients receiving ECT in routine clinical practice. METHOD:Patients (n = 535, of whom 277 were included in the final analysis) were recruited from eight Swedish hospitals. ... Read more >>

BJPsych Open (BJPsych open)
[2020, 6(2):e26]

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The Safety of Electroconvulsive Therapy in Cervical Fusion.

Nicholas Musgrave, Abaigael Madden, Mike Mehta, Evita Singh, Kevin Reeves,

J ECT (The journal of ECT)
[2020, :]

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Efficacy and Safety of Electroconvulsive Therapy in Adolescents: A Retrospective Chart Review Study From Turkey.

Ali Karayağmurlu, Murat Coşkun, Gülçin Elboğa, Neera Ghaziuddin, Elif Karayağmurlu, Cem Gökçen, Abdurrahman Altindağ,

OBJECTIVE:The aim of this study was to report the efficacy and safety of electroconvulsive therapy (ECT) in manic, depressed, psychotic, and catatonic adolescent patients. METHODS:Medical records of 78 adolescents who had received ECT in Department of Psychiatry, Gaziantep University Medical Faculty, during 2011 to 2017 were reviewed. Sixty-two subjects in ... Read more >>

J ECT (The journal of ECT)
[2020, 36(1):54-59]

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Motor Function Improvement After Electroconvulsive Therapy in a Parkinson's Disease Patient With Deep Brain Stimulator.

Liesbeth Volkaerts, Rick Roels, Filip Bouckaert,

In patients with a deep brain stimulator (DBS), electroconvulsive therapy (ECT) has proven to be a safe and effective treatment option after several medication failures in major depression, especially in the presence of psychotic symptoms. Electroconvulsive therapy has also proven to be effective in the treatment of Parkinson's disease (PD). ... Read more >>

J ECT (The journal of ECT)
[2020, 36(1):66-68]

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Clinical Effectiveness of Maintenance Electroconvulsive Therapy in Patients with Schizophrenia: A Retrospective Cohort Study.

Moshe Isserles, Jesse Remington, Tyler S Kaster, Zafiris J Daskalakis, Daniel M Blumberger,

OBJECTIVE:This study aimed to assess the clinical effectiveness and cognitive effects of maintenance electroconvulsive therapy (mECT) in patients with schizophrenia or schizoaffective disorder and explore factors associated with both outcomes. METHODS:In this retrospective cohort study, we examined clinical records of 47 patients with a Diagnostic and Statistical Manual of Mental ... Read more >>

J ECT (The journal of ECT)
[2020, 36(1):42-46]

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Electroconvulsive Therapy in Pregnancy: Safety, Best Practices, and Barriers to Care.

Sherrill Rose, Sarah K Dotters-Katz, Jeffrey A Kuller,

Importance:Approximately 10% to 16% of women meet diagnostic criteria for depression during pregnancy. Untreated maternal depression is associated with adverse pregnancy outcomes including premature birth, low birth weight, and fetal growth restriction. objective:The aim of this study is to review the current safety data on electroconvulsive therapy (ECT) in pregnancy ... Read more >>

Obstet Gynecol Surv (Obstetrical & gynecological survey)
[2020, 75(3):199-203]

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Physician estimated vs. self-reported subjective memory in depressed patients treated with electroconvulsive therapy.

Johan Stengård, Carl Johan Ekman, Ullvi Båve, Antoinette Lundahl, Mirwais Abawi, Mats Adler, Mikael Landén, Johan Lundberg,

Background: Subjective memory deficits are common in depression and during series of treatment with electroconvulsive therapy (ECT). There is a need for feasible assessment of memory deficit. In the Swedish National Quality Register for ECT, patients' subjective memory function is rated by a clinician. Self-ratings would be easier to administer.Objectives: ... Read more >>

Nord J Psychiatry (Nordic journal of psychiatry)
[2020, :1-7]

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[Electroconvulsive therapy in combination with psychotropic and non-psychotropic pharmacological treatments: Review of the literature and practical recommendations].

C Quiles, A Dewitte, P Thomas, F Nunes, H Verdoux, A Amad,

CONTEXT:Electro-convulsive therapy (ECT) is the most effective treatment for treatment resistant mood disorders and catatonia. ECT also appears to be an effective treatment in combination with clozapine in the context of treatment resistant schizophrenia spectrum disorders. Although increasingly codified (guidelines on indications, contraindications, methods of implementation), the practice of ECT ... Read more >>

Encephale (L'Encephale)
[2020, :]

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Serum neurofilament light chain (NFL) remains unchanged during electroconvulsive therapy.

Matthias Besse, Michael Belz, Thorsten Folsche, Jonathan Vogelgsang, Isabel Methfessel, Petra Steinacker, Markus Otto, Jens Wiltfang, David Zilles,

Objectives: Although there is consistent evidence that electroconvulsive therapy (ECT) is safe and well tolerated by the majority of patients, some authors still accuse ECT to inevitably cause brain damage and permanent memory loss, assertions that may increase patients' worries about a useful treatment. Recently, the measurement of neurofilament light ... Read more >>

World J. Biol. Psychiatry (The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry)
[2020, :1-7]

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Prophylactic cognitive enhancers for improvement of cognitive function in patients undergoing electroconvulsive therapy: A systematic review and meta-analysis.

Yunlian Niu, Dan Ye, Yijie You, Jian Wu,

OBJECTIVE:Cognitive enhancers, including cholinesterase inhibitors and memantine, are used to treat dementia, but their effect for reducing post-electroconvulsive therapy (post-ECT) cognitive side effects is unclear. We conducted a systematic review and meta-analysis to assess the effectiveness of cognitive enhancers in the prevention of cognitive side effects due to ECT. METHODS:We ... Read more >>

Medicine (Baltimore) (Medicine)
[2020, 99(11):e19527]

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Electroconvulsive Seizures Induce Autophagy by Activating the AMPK Signaling Pathway in the Rat Frontal Cortex.

Se Hyun Kim, Hyun Sook Yu, Soyoung Park, Hong Geun Park, Yong Min Ahn, Ung Gu Kang, Yong Sik Kim,

BACKGROUND:It is uncertain how electroconvulsive therapy-induced generalized seizures exert their potent therapeutic effects on various neuropsychiatric disorders. Adenosine monophosphate-activated protein kinase (AMPK) plays a major role in maintaining metabolic homeostasis and activates autophagic processes via unc-51-like kinase (ULK1). Evidence supports the involvement of autophagy system in the action mechanisms of ... Read more >>

Int. J. Neuropsychopharmacol. (The international journal of neuropsychopharmacology)
[2020, 23(1):42-52]

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Electroconvulsive Therapy for the Treatment of Severe Mood Disorders During Adolescence: A Retrospective Chart Review.

Neera Ghaziuddin, Wael Shamseddeen, George Gettys, Mohammad Ghaziuddin,

Objective: Electroconvulsive therapy (ECT) is a well-recognized treatment of refractory mood disorders in adults. However, relatively little is known about its use for similar conditions in adolescents. Based on a chart review, we describe its use and outcome in a sample of adolescents with severe, refractory mood disorders (unipolar or ... Read more >>

J Child Adolesc Psychopharmacol (Journal of child and adolescent psychopharmacology)
[2020, :]

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Ketamine plus propofol-electroconvulsive therapy (ECT) transiently improves the antidepressant effects and the associated brain functional alterations in patients with propofol-ECT-resistant depression.

Jianjing Zhang, Hongjun Tian, Jie Li, Shengzhang Ji, Suling Chen, Jingjing Zhu, Deguo Jiang, Lina Wang, Gongying Li, Min Chen, Wenqiang Wang, Xiaodong Lin, Chuanjun Zhuo,

New methods for using ketamine in patients with propofol-electroconvulsive therapy-resistant depression (ECT-RD) are needed in the clinic. This study aimed to investigate the therapeutic efficacy of ketamine plus ECT in ECT-RD patients, along with the treatment-induced brain alterations. A total of 28 ECT-RD patients were intravenously injected with ketamine six ... Read more >>

Psychiatry Res (Psychiatry research)
[2020, 287:112907]

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Increased Risk of Pain after Electroconvulsive Therapy among Depressed Patients: a Nationwide Study in Taiwan.

Ching-En Lin, Chi-Hsiang Chun, Li-Fen Chen, Wu-Chien Chien,

The risk of pain after electroconvulsive therapy (ECT) among depressed patients is still controversial. We aimed to investigate the risk of pain post-ECT among patients with depression. We investigated patients with depression, based on the data in the National Health Insurance Research Database. A comparison cohort comprising depressed non-ECT patients ... Read more >>

Psychiatr Q (The Psychiatric quarterly)
[2020, 91(1):237-250]

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A Descriptive Study of Data Collection Systems Used in Electroconvulsive Therapy Units in the Province of Quebec, Canada.

Julie Haesebaert, Alexander Moreno, Alain Lesage, Simon Patry, Morgane Lemasson,

OBJECTIVES:This study aimed to describe the data collection systems routinely used by electroconvulsive therapy (ECT) units across the province of Quebec, Canada. METHODS:We conducted a descriptive, cross-sectional study. Using an online survey, 31 ECT units delivering inpatient or outpatient ECT treatments in the province of Quebec provided information on the ... Read more >>

J ECT (The journal of ECT)
[2020, 36(1):36-41]

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Catalpol and Mannitol, Two Components of Rehmannia glutinosa, Exhibit Anticonvulsant Effects Probably via GABAA Receptor Regulation.

Mikyung Kim, Srijan Acharya, Chrislean Jun Botanas, Raly James Custodio, Hyun Jun Lee, Leandro Val Sayson, Arvie Abiero, Yong Soo Lee, Jae Hoon Cheong, Kyeong-Man Kim, Hee Jin Kim,

Epilepsy is a brain disorder that affects millions of people worldwide and is usually managed using currently available antiepileptic drugs, which result in adverse effects and are ineffective in approximately 20-25% of patients. Thus, there is growing interest in the development of new antiepileptic drugs with fewer side effects. In ... Read more >>

Biomol Ther (Seoul) (Biomolecules & therapeutics)
[2020, 28(2):137-144]

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Cognitive function after electroconvulsive therapy for depression: relationship to clinical response.

Ian M Anderson, R Hamish McAllister-Williams, Darragh Downey, Rebecca Elliott, Colleen Loo,

BACKGROUND:As uncertainty remains about whether clinical response influences cognitive function after electroconvulsive therapy (ECT) for depression, we examined the effect of remission status on cognitive function in depressed patients 4 months after a course of ECT. METHOD:A secondary analysis was undertaken on participants completing a randomised controlled trial of ketamine ... Read more >>

Psychol Med (Psychological medicine)
[2020, :1-10]

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Over the Cuckoo's Nest: Does Experiencing Electroconvulsive Therapy Change Your Mind? A Mixed Methods Study of Attitudes and Impact of Electroconvulsive Therapy on Patients and Their Relatives.

Lauren Alexander, Louisa Kelly, Eimear Doody, Shane Brady, Darren Roddy, Eimear Counihan, Liam Delaney, Declan McLoughlin, Kevin Malone,

OBJECTIVE:Electroconvulsive therapy (ECT) is an effective treatment for major depressive disorder, but some aspects remain controversial. Few studies have taken an in-depth mixed methods approach toward the study of attitudes, and there are no significant studies that explore the change of attitudes before and after treatment. The aim was to ... Read more >>

J ECT (The journal of ECT)
[2020, :]

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