Full Text Journal Articles about
Disorders of Carbohydrate Metabolism

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Differences in fatty acid profiles and desaturation indices of abdominal subcutaneous adipose tissue between pregnant women with and without PCOS.

Neda Emami, AliReza Alizadeh, Ashraf Moini, Parichehreh Yaghmaei, Maryam Shahhosseini,

The objective was to determine the differences in fatty acid (FA) profiles in subcutaneous adipose tissue (AT) between pregnant women with polycystic ovary syndrome (PCOS) and those without PCOS. FA profiles of AT samples from 13 PCOS and 32 non-PCOS, all of whom underwent caesarean section were compared using gas ... Read more >>

Adipocyte (Adipocyte)
[2020, 9(1):16-23]

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Effect of Vanadium Complex with Enzymatic Hydrolysate of Soy Protein on Carbohydrate and Lipid Metabolism Disorders in Male Wistar Rats.

Yu S Sidorova, S N Zorin, N A Petrov, A A Shumakova, Yu V Frolova, V K Mazo,

The effects of vanadium complex with enzymatic hydrolysate of soy protein (V-EHSPI) were studied in male Wistar rats with induced disorders of carbohydrate and lipid metabolism. The content of vanadium (IV) in the studied complex was 15.8 mg/g dry product. High-lipid high-carbohydrate diet was used to induce disorders of lipid ... Read more >>

Bull. Exp. Biol. Med. (Bulletin of experimental biology and medicine)
[2020, :]

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To treat or not to treat Alzheimer's disease by the ketogenic diet? That is the question.

Marzena Ulamek-Koziol, Ryszard Pluta,

Neural Regen Res (Neural regeneration research)
[2020, 15(5):857-858]

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Atypical antipsychotics, more than just an antipsychotic.

Hiram Tendilla-Beltran, Gonzalo Flores,

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1477-1478]

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Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus.

Courtney J Mycroft-West, Anthony J Devlin, Lynsay C Cooper, Patricia Procter, Gavin J Miller, David G Fernig, Marco Guerrini, Scott E Guimond, Marcelo A Lima, Edwin A Yates, Mark Andrew Skidmore,

The pharmaceutical and anticoagulant agent heparin, a member of the glycosaminoglycan family of carbohydrates, has previously been identified as a potent inhibitor of a key Alzheimer's disease drug target, the primary neuronal β-secretase, β-site amyloid precursor protein cleaving enzyme 1 (BACE1). The anticoagulant activity of heparin has, however, precluded the ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1546-1553]

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High Levels of Glycosaminoglycans in the Urines of Children with Attention-Deficit/Hyperactivity Disorder (ADHD).

Ildikó Endreffy, Geir Bjørklund, Mauricio A Urbina, Salvatore Chirumbolo, Monica Daniela Doşa, Ferenc Dicső,

Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral/neurodevelopmental disorder. Some early studies indicated that increased intake of added sugars might have a role in ADHD. In the present study, we tested this possibility by evaluating the urinary excretion of oligosaccharides and glycosaminoglycans (GAGs) in ADHD and control subjects. Forty ADHD subjects ... Read more >>

J. Mol. Neurosci. (Journal of molecular neuroscience : MN)
[2020, :]

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Letter to the Editor on "The efficacy comparison of classic ketogenic diet and modified Atkins diet in children with refractory epilepsy: a clinical trial".

Shahabeddin Rezaei,

Acta Neurol Belg (Acta neurologica Belgica)
[2020, :]

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Association between a low-carbohydrate diet and sleep status, depression, anxiety, and stress score.

Elnaz Daneshzad, Seyed-Ali Keshavarz, Mostafa Qorbani, Bagher Larijani, Leila Azadbakht,

BACKGROUND:Dietary intakes, especially carbohydrates, play an important role in blood glucose control in patients with diabetes. It is suggested that carbohydrate amounts may be effective in diabetes complications. This study aimed to reveal the association of low-carbohydrate diet (LCD) and sleep and mental status among patients with diabetes. METHODS:This cross-sectional ... Read more >>

J. Sci. Food Agric. (Journal of the science of food and agriculture)
[2020, :]

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Antidepressant effect of Gentiana olivieri Griseb. in male rats exposed to chronic mild stress.

Ahmet Berk, İsmet Yılmaz, Nurettin Abacıoğlu, Mustafa Bahadır Kaymaz, Merve Gökşin Karaaslan, Ebru Kuyumcu Savan,

Background: The flowering parts of Gentiana olivieri, known as 'Afat' in the southeastern Anatolia region of Turkey, are used as a tonic, an appetizer, and for the treatment of several mental disorders, including depression. The purpose of this study is to investigate the antidepressant effect of G. olivieri ethanol extract ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2020, 15(1):1725991]

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Consumption of salt leads to ameliorate symptoms of metabolic disorder and change of gut microbiota.

Moon Ho Do, Hye-Bin Lee, Mi-Jin Oh, Hyunjhung Jhun, Sang Keun Ha, Ho-Young Park,

PURPOSE:Metabolic diseases caused by high-carbohydrate and/or high-salt diets are becoming major public health concerns. However, the effects of salt on high-carbohydrate diet-induced obesity are unclear. Accordingly, in this study, we investigated the effects of high-salt intake on high-carbohydrate diet-induced obesity. METHODS:We performed a 12-week study on gut microbiota and metabolic ... Read more >>

Eur J Nutr (European journal of nutrition)
[2020, :]

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Post-translational protein modifications in schizophrenia.

Toni M Mueller, James H Meador-Woodruff,

Research investigating the pathophysiology of schizophrenia has not yet precisely defined the molecular phenotype of this disorder. Many studies have investigated cellular dysfunction by examining expression levels of molecular targets in postmortem patient brain; however, inconsistencies between transcript and protein measures in schizophrenia are common in the field and represent ... Read more >>

NPJ Schizophr (NPJ schizophrenia)
[2020, 6(1):5]

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Effect of exercise and dietary intervention on serum metabolomics in men with insomnia symptoms: a 6-month randomized-controlled trial

Xiaobo Zhang, Xiuqiang Wang, Shenglong Le, Xiaowei Ojanen, Xiao Tan, Petri Wiklund, Sulin Cheng,

Background: Accumulating evidences have shown that lifestyle interventions such as exercise and diet are associated with improved sleep quality. However, the underlying molecular mechanisms remain unclear. Assessing exercise and diet intervention associated changes in circulating metabolomics profile in people with insomnia symptoms may help to identify molecular biomarkers that may ... Read more >>

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Comparative Genomics of Pediococcus pentosaceus Isolated From Different Niches Reveals Genetic Diversity in Carbohydrate Metabolism and Immune System.

Jie Jiang, Bo Yang, R Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang, Wei Chen,

Pediococcus pentosaceus isolated from fermented food and the gastrointestinal tracts of humans and animals have been widely identified, and some strains have been reported to reduce inflammation, encephalopathy, obesity and fatty liver in animals. In this study, the genomes of 65 P. pentosaceus strains isolated from human and animal feces ... Read more >>

Front Microbiol (Frontiers in Microbiology)
[2020, 11:253]

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Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice.

Clara Depommier, Matthias Van Hul, Amandine Everard, Nathalie M Delzenne, Willem M De Vos, Patrice D Cani,

Accumulating evidence points to Akkermansia muciniphila as a novel candidate to prevent or treat obesity-related metabolic disorders. We recently observed, in mice and in humans, that pasteurization of A. muciniphila increases its beneficial effects on metabolism. However, it is currently unknown if the observed beneficial effects on body weight and ... Read more >>

Gut Microbes (Gut microbes)
[2020, :1-15]

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Low utilization of glucose in the liver causes diet-induced hypercholesterolemia in exogenously hypercholesterolemic rats.

Yasutake Tanaka, Masahiro Ono, Motonori Miyago, Takahisa Suzuki, Yurika Miyazaki, Michio Kawano, Makoto Asahina, Bungo Shirouchi, Katsumi Imaizumi, Masao Sato,

Exogenously hypercholesterolemic (ExHC) rats develop diet-induced hypercholesterolemia (DIHC) when fed with dietary cholesterol. Previously, we reported that, under the high-sucrose-diet-feeding condition, a loss-of-function mutation in Smek2 results in low activity of fatty acid synthase (FAS) followed by the shortage of hepatic triacylglycerol content in ExHC rats and the onset of ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0229669]

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Prevalence and progression of carbohydrate disorders in patients with pheochromocytoma/paraganglioma: retrospective single-center study.

Atanaska Elenkova, Joannna Matrozova, Vladimir Vasilev, Ralitsa Robeva, Sabina Zacharieva,

BACKGROUND:Carbohydrate disorders are the most frequent metabolic disorders, affecting a significant proportion of patients with pheochromocytoma. OBJECTIVE:A retrospective study assessed the prevalence and progression of carbohydrate disorders in 204 patients (92 men, 112 women) with histologically proven pheochromocytoma diagnosed in a single specialized tertiary center during a 40-year period (1978-2017). One hundred were ... Read more >>

Ann. Endocrinol. (Paris) (Annales d'endocrinologie)
[2020, 81(1):3-10]

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Ketogenic therapy in neurodegenerative and psychiatric disorders: From mice to men.

Ann-Katrin Kraeuter, Riana Phillips, Zoltán Sarnyai,

Ketogenic diet is a low carbohydrate and high fat diet that has been used for over 100 years in the management of childhood refractory epilepsy. More recently, ketogenic diet has been investigated for a number of metabolic, neurodegenerative and neurodevelopmental disorders. In this comprehensive review, we critically examine the potential ... Read more >>

Prog. Neuropsychopharmacol. Biol. Psychiatry (Progress in neuro-psychopharmacology & biological psychiatry)
[2020, 101:109913]

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Association of colitis with gut-microbiota dysbiosis in clathrin adapter AP-1B knockout mice.

Aditi Jangid, Shinji Fukuda, Masahide Seki, Terumi Horiuchi, Yutaka Suzuki, Todd D Taylor, Hiroshi Ohno, Tulika Prakash,

Inflammatory bowel disease results from alterations in the immune system and intestinal microbiota. The role of intestinal epithelial cells (IECs) in maintaining gut homeostasis is well known and its perturbation often causes gastrointestinal disorders including IBD. The epithelial specific adaptor protein (AP)-1B is involved in the establishment of the polarity ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0228358]

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All-Trans Retinoic Acid (atRA) effectively improves liver steatosis in a rabbit model of high fat induced liver steatosis.

Leila Zarei, Negin Farhad, Ata Abbasi,

The aim of this study is to evaluate the role of All-Trans Retinoic Acid, the biologically active metabolite of retinoids, on liver steatosis in a rabbit model of high fat induced lever steatosis. 30 male rabbits were evaluated in 5 groups: group 1 treated with normal diet, group 2-5 included ... Read more >>

Arch. Physiol. Biochem. (Archives of physiology and biochemistry)
[2020, :1-6]

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Prevalence of mild cognitive impairment in type 2 diabetes mellitus is associated with serum Galectin-3 level.

Shizhan Ma, Shangbin Li, Renjun Lv, Xunyao Hou, Shanjing Nie, Qingqing Yin,

INTRODUCTION:Galectin-3 (Gal3) contributes to insulin resistance, inflammation, and obesity, the three risk factors for mild cognitive impairment (MCI) in type 2 diabetes mellitus (T2DM) patients. PATIENTS AND METHODS:134 hospitalized T2DM patients were assessed by the Montreal Cognitive Assessment (MoCA) method and divided into 65 MCI and 69 controls. Levels of ... Read more >>

J Diabetes Investig (Journal of diabetes investigation)
[2020, :]

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Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes.

Sevda Gheibi, Alan P Samsonov, Shahsanam Gheibi, Alexandra B Vazquez, Khosrow Kashfi,

Nitric oxide (NO) and hydrogen sulfide (H2S) are two gasotransmitters that are produced in the human body and have a key role in many of the physiological activities of the various organ systems. Decreased NO bioavailability and deficiency of H2S are involved in the pathophysiology of type 2 diabetes and ... Read more >>

Biochem. Pharmacol. (Biochemical pharmacology)
[2020, :113819]

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Volumetric Food Quantification Using Computer Vision on a Depth-Sensing Smartphone: Preclinical Study.

David Herzig, Christos T Nakas, Janine Stalder, Christophe Kosinski, Céline Laesser, Joachim Dehais, Raphael Jaeggi, Alexander Benedikt Leichtle, Fried-Michael Dahlweid, Christoph Stettler, Lia Bally,

BACKGROUND:Quantification of dietary intake is key to the prevention and management of numerous metabolic disorders. Conventional approaches are challenging, laborious, and lack accuracy. The recent advent of depth-sensing smartphones in conjunction with computer vision could facilitate reliable quantification of food intake. OBJECTIVE:The objective of this study was to evaluate the ... Read more >>

JMIR Mhealth Uhealth (JMIR mHealth and uHealth)
[2020, 8(3):e15294]

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Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity.

Maria Ballester, Raquel Quintanilla, Francisco J Ortega, José C E Serrano, Anna Cassanyé, Maria Rodríguez-Palmero, José A Moreno-Muñoz, Manuel Portero-Otin, Joan Tibau,

Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue transcriptomes of a porcine model for prepubertal early obesity induced by a high-calorie diet and supplemented with bioactive ingredients. ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):5375]

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Nutritional Recommendations for Physique Athletes.

Brandon M Roberts, Eric R Helms, Eric T Trexler, Peter J Fitschen,

The popularity of physique sports is increasing, yet there are currently few comprehensive nutritional guidelines for these athletes. Physique sport now encompasses more than just a short phase before competition and offseason guidelines have recently been published. Therefore, the goal of this review is to provide an extensive guide for ... Read more >>

J Hum Kinet (Journal of human kinetics)
[2020, 71:79-108]

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Transcriptome analysis of acute exposure of the Manila clam, Ruditapes philippinarum to perfluorooctane sulfonate (PFOS).

Linbao Zhang, Wei Sun, Haigang Chen, Fei Tian, Wengui Cai,

Perfluorooctane sulfonate (PFOS) is an increasingly important environmental pollutant, which has been detected almost everywhere in the environment. Despite the widespread presence of PFOS, much less notice is taken of its toxicology effects on marine bivalves. Thus, the transcriptome response to PFOS treatment (nominal concentration of 20 mg/L) in hepatopancreas of ... Read more >>

Comp. Biochem. Physiol. C Toxicol. Pharmacol. (Comparative biochemistry and physiology. Toxicology & pharmacology : CBP)
[2020, 231:108736]

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