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Effects of hemodialysis treatment on saliva flow rate and saliva composition during in-center maintenance dialysis: a cross-sectional study.

I-Chen Yu, Chieh-Yu Liu, Ji-Tseng Fang,

<h4>Aim</h4>To analyze changes in saliva flow rate and clinical measures from unstimulated whole saliva (UWS) among patients undergoing hemodialysis for end-stage kidney disease (ESKD).<h4>Background</h4>Chronic hemodialysis causes changes in blood chemistry as well as dry mouth, due to removal of excess fluids. UWS is used to examine saliva flow rate as ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):71-78]

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Relationship between doses of antihypertensive drugs and left ventricular mass index changes in hemodialysis patients in a Japanese cohort.

Fumiya Kitamura, Makoto Yamaguchi, Takayuki Katsuno, Hironobu Nobata, Shiho Iwagaitsu, Hirokazu Sugiyama, Hiroshi Kinashi, Shogo Banno, Masahiko Ando, Yoko Kubo, Yasumasa Kawade, Iwashima Shigejiro, Yutaka Ito, Takuji Ishimoto, Yasuhiko Ito,

Left ventricular hypertrophy commonly occurs in dialysis patients and is associated with a risk of developing cardiovascular disease events and all-cause mortality. Although hypertension treatment reduces left ventricular mass index (LVMI) in hemodialysis patients, the relationships of prescription pattern, dose, and changes in the dose of antihypertensive drugs with LVMI ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):188-197]

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Effect of clinical factors on trajectory of functional performance in patients undergoing hemodialysis.

Jin-Bor Chen, Lung-Chih Li, Wen-Chin Lee, Sin-Hua Moi, Cheng-Hong Yang,

<h4>Purpose</h4>This study aimed to investigate the association between clinical factors and temporary changes in functional performance in patients undergoing hemodialysis.<h4>Methods</h4>This was a retrospective, longitudinal observational study conducted from 2015 to 2017. Eight-two patients undergoing hemodialysis in the outpatient clinic were enrolled. Functional performance was measured using the Karnofsky Performance Status ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):90-96]

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Risk factors and outcomes of cardiovascular disease readmission within the first year after dialysis in peritoneal dialysis patients.

Jianbo Li, Naya Huang, Zhong Zhong, Pema Joe, Dan Wang, Zhen Ai, Lisha Wu, Lanping Jiang, Fengxian Huang,

<h4>Background</h4>In the first year of dialysis, patients are vulnerable to cardiovascular disease (CVD) hospitalization, but knowledge regarding the risk factors and long-term outcomes of cardiovascular readmission within the first year after dialysis in incident continuous ambulatory peritoneal dialysis (CAPD) patients is limited.<h4>Methods</h4>This retrospective cohort study was conducted in incident CAPD ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):159-167]

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Clinical features and outcome of maintenance hemodialysis patients with COVID-19 from a tertiary nephrology care center in Romania.

Gabriel Stefan, Ana Maria Mehedinti, Iuliana Andreiana, Adrian Dorin Zugravu, Simona Cinca, Ruxandra Busuioc, Ioana Miler, Simona Stancu, Ligia Petrescu, Ioana Dimitriu, Elena Moldovanu, Diana Elena Crasnaru, Georgeta Gugonea, Valentin Georgescu, Victor Dan Strambu, Cristina Capusa,

<h4>Background</h4>There is limited information about the clinical characteristics, treatment and outcome of maintenance hemodialysis patients with COVID-19. Moreover, regional differences are also conceivable since the extend and severity of outbreaks varied among countries.<h4>Methods</h4>In this retrospective, observational, single-center study, we analyzed the clinical course and outcomes of 37 maintenance hemodialysis patients ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):49-57]

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High ultrafiltration rate induced intradialytic hypotension is a predictor for cardiac remodeling: a 5-year cohort study.

Jinbo Yu, Xiaohong Chen, Yang Li, Yaqiong Wang, Zhonghua Liu, Bo Shen, Jie Teng, Jianzhou Zou, Xiaoqiang Ding,

<h4>Background</h4>Intradialytic-hypotension (IDH) is a common complication of hemodialysis. High ultrafiltration rate (UFR) might lead to IDH. However, the relationships between UFR, IDH, and cardiac remodeling among hemodialysis patients in the long-term have not been deeply explored.<h4>Methods</h4>This retrospective cohort study collected clinical and echocardiographic data. Patients were enrolled from 1 January ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):40-48]

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Pro-inflammatory cytokines as potential predictors for intradialytic hypotension.

Jinbo Yu, Xiaohong Chen, Yang Li, Yaqiong Wang, Xuesen Cao, Zhonghua Liu, Bo Shen, Jianzhou Zou, Xiaoqiang Ding,

<h4>Background</h4>Intradialytic hypotension (IDH) is a common complication in maintaining hemodialysis (MHD) patients. Immune activation might be part of the mechanisms. However, the association between pro-inflammatory cytokines and blood pressure (BP) has not been deeply explored. So we aim to evaluate the potential role of pro-inflammatory cytokines in IDH.<h4>Methods</h4>MHD patients starting ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):198-205]

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Correlates of objective sleep quality in older peritoneal dialysis patients.

Haifen Zhang, Yan Yang, Jiaying Huang, Shuhui Lailan, Xingjuan Tao,

<h4>Background</h4>Sleep disturbance is a prominent concern in dialysis patients and detrimentally impacts clinical and self-reported health outcomes. This study aimed to collect sleep data from in-home actigraphy and to explore possible predictors of sleep quality in older peritoneal dialysis patients.<h4>Methods</h4>This was a cross-sectional study. Peritoneal dialysis patients aged ≥60 years ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):180-187]

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Acute effects of dietary phosphorus intake on markers of mineral metabolism in hemodialysis patients: post hoc analysis of a randomized crossover trial.

Wan-Chuan Tsai, Hon-Yen Wu, Yen-Ling Chiu, Ju-Yeh Yang, Mei-Fen Pai, Yong-Ru Wu, Wan-Yu Lin, Kuan-Yu Hung, Kuo-Liong Chien, Shih-Ping Hsu, Yu-Sen Peng,

<h4>Background</h4>Long-term dietary phosphorus excess influences disturbances in mineral metabolism, but it is unclear how rapidly the mineral metabolism responds to short-term dietary change in dialysis populations.<h4>Methods</h4>This was a post hoc analysis of a randomized crossover trial that evaluated the short-term effects of low-phosphorus diets on mineral parameters in hemodialysis patients. ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):141-148]

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The impact of location and patency of the arteriovenous fistula on quality of life of kidney transplant recipients.

Krzysztof Letachowicz, Klaudia Bardowska, Tomasz Królicki, Dorota Kamińska, Mirosław Banasik, Karolina Zajdel, Oktawia Mazanowska, Katarzyna Madziarska, Dariusz Janczak, Magdalena Krajewska,

<h4>Background</h4>Arteriovenous fistulae (AVFs) may remain patent after kidney transplantation (KTx), contributing to maladaptive cardiac remodeling. The flow in AVFs is associated with the diameter of its vessels and thus with the AVF location. The main objective of this study is to assess the influence of AVF location and its patency ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):113-122]

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Three cases of retained cuff related infection after manual pull removal of peritoneal dialysis catheter.

Suojian Zhang, Xu Zhang, Haitao Li, Zhiqiang Wei, Juan Cao,

Ren Fail (Renal failure)
[2021, 43(1):58-61]

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Renal replacement therapy in acute kidney injury.

Vincenzo Sepe, Teresa Rampino, Carmelo Libetta,

Lancet (Lancet (London, England))
[2021, 396(10267):1974]

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Distal radial approach versus conventional radial approach: a comparative study of feasibility and safety.

Rania Hammami, Fatma Zouari, Mohamed Aymen Ben Abdessalem, Awatef Sassi, Tarek Ellouze, Amine Bahloul, Souad Mallek, Faten Triki, Abdallah Mahdhaoui, Gouider Jeridi, Leila Abid, Selma Charfeddine, Samir Kammoun, Jihen Jdidi,

The distal radial approach (DRA) is suggested to have benefits over the conventional radial approach (CRA) in terms of local complications and comfort of both patient and operator. Therefore, we aimed to compare the feasibility and safety of DRA and CRA in a real life population. We conducted a prospective, ... Read more >>

Libyan J Med (The Libyan journal of medicine)
[2021, 16(1):1830600]

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Clinicopathological characteristics and predictors of poor outcome in anti-glomerular basement membrane disease - a fifteen year single center experience.

Zafirah Zahir, Asif Sadiq Wani, Narayan Prasad, Manoj Jain,

<h4>Introduction</h4>Anti-glomerular basement membrane (anti-GBM) disease is a small vessel vasculitis affecting the renal and lung capillary beds. We aim to study the clinicopathological characteristics and predictors of poor outcome of this disease in our population.<h4>Materials and methods</h4>This is a 15 year retrospective, single center observational study of Indian cohort. Patients with ... Read more >>

Ren Fail (Renal failure)
[2021, 43(1):79-89]

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Sustained remission of rapidly progressive post-transplant immunoglobulin A nephropathy by treatment with tonsillectomy following steroid pulse therapy: a case report.

Aoi Yamashiro, Muneharu Yamada, Yu Kihara, Osamu Konno, Hitoshi Iwamoto, Takashi Oda,

Ren Fail (Renal failure)
[2021, 43(1):16-19]

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Discovery of orally active chalcones as histone lysine specific demethylase 1 inhibitors for the treatment of leukaemia.

Yang Li, Ying Sun, Yang Zhou, Xinyang Li, Huan Zhang, Guojun Zhang,

Histone lysine specific demethylase 1 (LSD1) has emerged as an attractive molecule target for the discovery of potently anticancer drugs to treat leukaemia. In this study, a series of novel chalcone derivatives were designed, synthesised and evaluated for their inhibitory activities against LSD1 <i>in vitro</i>. Among all these compounds, <b>D6</b> displayed ... Read more >>

J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2021, 36(1):207-217]

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A systematic review of the epidemiology of Hepatitis E virus infection in South - Eastern Asia.

Yakubu Egigogo Raji, Ooi Peck Toung, Niazlin Mohd Taib, Zamberi Bin Sekawi,

Hepatitis E virus (HEV) infection is an emerging zoonotic viral disease, with an increasingly international public health challenge. Despite the concerns that the global disease burden may be underestimated. Therefore, evaluation of the disease epidemiology in South - eastern Asia through a systematic review will assist in unraveling the burden ... Read more >>

Virulence (Virulence)
[2021, 12(1):114-129]

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Challenge in diagnosis of COVID-19 in hemodialysis patient: a case report and brief review of the literature.

Rizky Andhika, Afiatin Makmun, Yovita Hartantri, Indra Wijaya, Ian Huang,

Diagnosis of COVID-19 in end-stage kidney disease (ESKD) patients on hemodialysis is challenging,  as the symptoms are often atypical. Herein, we reported a confimed case of COVID-19 in a patient on maintenance hemodialysis. A 38-year-old man with ESKD on regular hemodialysis initially presented with progressive shortness of breath and dry cough, without fever. He ... Read more >>

CEN Case Rep (CEN case reports)
[2021, :]

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A hemodialysis curriculum for nephrology fellows using a blended learning approach: best of both worlds?

Namrata Krishnan,

A comprehensive, hands-on hemodialysis curriculum during nephrology training is necessary for effective learning and optimal patient care. Traditional instructive approaches are unable to fully meet the needs of the digitally inclined learner and are limited by time constraints and increasing clinical workload. Internet based learning (E-learning) is becoming increasingly popular ... Read more >>

J Nephrol (Journal of nephrology)
[2021, :]

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Cardiac Arrhythmia During Early-Week and Mid-Week Dialysis in Hemodialysis Patients.

Kornchanok Vareesangthip, Picha Yincharoen, Arjbordin Winijkul, Thawee Chanchairujira,

Data on cardiac arrhythmia and electrolyte changes during the dialysis cycle has been limited. Fifty-two hemodialysis(HD) patients underwent 48-hour Holter monitoring during early-week and mid-week HD sessions. Pre-HD and post-HD blood samples were collected in both HD sessions. The 48-hour Holter data were divided into 5 phases: 1) 4-hour during ... Read more >>

Ther Apher Dial (Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy)
[2021, :]

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Application of Individualized PBPK Modeling of Rate Data (iPBPK-R) to Evaluate the Effect of Hemodialysis On Nonrenal Clearance Pathways.

Yoko Franchetti, Thomas D Nolin,

The aim of this study was to apply individualized, physiologically-based pharmacokinetic (iPBPK-R) modeling of <sup>14</sup> CO<sub>2</sub> production rates measured by the erythromycin breath test (ERMBT) to characterize the effect of hemodialysis on the function of nonrenal clearance pathways in patients with end-stage renal disease (ESRD). Twelve patients previously received <sup>14</sup> ... Read more >>

J Clin Pharmacol (Journal of clinical pharmacology)
[2021, :]

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Music-based interventions for pain relief in patients undergoing hemodialysis : A PRISMA-compliant systematic review and meta-analysis

Jingru Cheng, Hui Zhang, Hong Bao, Hanxia Hong, Manal Kamel Youssef.,

Supplemental Digital Content is available in the text Abstract <h4>Background:</h4> Music therapy and music-based interventions have been used widely in numerous medical procedures to reduce the physical and psychological disorders. However, the effect of music therapy on pain relief in hemodialysis patients still remains unclear. <h4>Methods:</h4> Electronic databases were comprehensively ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(2):]

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Effectiveness of monitoring free carnitine levels for L-carnitine supplementation in hemodialysis patients to maintain carnitine sufficiency and nutritional factors.

Etsuko Kumagai, Keiko Hosohata, Kazuhiro Furumachi, Shinji Takai,

<h4>Introduction</h4>We investigated the effectiveness of monitoring serum carnitine levels in hemodialysis patients receiving L-carnitine supplementation.<h4>Methods</h4>One-hundred forty-five hemodialysis patients were divided into three groups. Group 1 consisted of patients (n=30) who had been receiving supplementation prior to this study and then discontinued at the beginning. The remaining patients were divided into ... Read more >>

Ther Apher Dial (Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy)
[2021, :]

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[Prevalence, Costs of Medical Treatment and Modalities of Dialysis-dependent Chronic Renal Failure in Germany: Comparison of Dialysis Care of Nursing Home Residents and in Outpatient Units].

Dennis Häckl, Nils Kossack, Tonio Schoenfelder,

<h4>Study objectives</h4>Current estimates on the prevalence of chronic renal failure and the costs of dialysis in Germany's population are not available. The aim of this study was to assess the prevalence of dialysis-dependent chronic renal failure and treatment costs of dialysis-dependent patients in Germany as well as differences between those ... Read more >>

Gesundheitswesen (Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)))
[2021, :]

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Baseline serum triglyceride predicts early-onset peritonitis and prognosis in incident CAPD patients

Sheng Wan, Hongdan Tian, Li Cheng, Yanqiong Ding, Qing Luo, Yanmin Zhang, Jiannan Li.,

Abstract We aimed to investigate the hypothesis that serum triglyceride (TG) may be an independent predictor of early-onset peritonitis and prognosis in incident continuous ambulatory peritoneal dialysis (CAPD) patients. In this retrospective, observational study, we screened 291 adults admitted to the PD center of the Wuhan No. 1 hospital from ... Read more >>

Medicine (Baltimore) (Medicine)
[2021, 100(2):]

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