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The Dose Makes the Poison: A Case Report of Acquired Methemoglobinemia.

Giulia Cannata, Luciana Abate, Chiara Scarabello, Monica Rubini, Alessandra Giacometti, Nicola Principi, Susanna Esposito, Icilio Dodi,

Background: Methemoglobinemia (MET) should be suspected in cases where cyanosis is not associated with signs and symptoms of lung and/or heart disease, or in a cyanotic child exhibiting discrepancies in the partial pressure of oxygen in the arterial blood, the blood oxygen saturation, and the clinical assessment. Case presentation: A ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(6):]

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Risk factors for death from hand-foot-mouth disease: a meta-analysis.

X F Ni, X Li, C Xu, Q Xiong, B Y Xie, L H Wang, Y H Peng, X W Li,

In recent years, outbreaks of hand-foot-mouth disease (HFMD) in China, Singapore and other Western Pacific Region, involving millions of children, have become a big threat to public health. This study aimed to quantitatively assess all qualified studies and identify the risk factors for HFMD death. A systematic search of the ... Read more >>

Epidemiol. Infect. (Epidemiology and infection)
[2020, 148:e44]

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Predictors of neonatal mortality: development and validation of prognostic models using prospective data from rural Bangladesh.

Farhad A Khan, Luke C Mullany, Lee F-S Wu, Hasmot Ali, Saijuddin Shaikh, Kelsey Alland, Keith P West, Alain B Labrique,

Objective:To assess the extent to which maternal histories of newborn danger signs independently or combined with birth weight and/or gestational age (GA) can capture and/or predict postsecond day (age>48 hours) neonatal death. Methods:Data from a cluster-randomised trial conducted in rural Bangladesh were split into development and validation sets. The prompted recall ... Read more >>

BMJ Glob Health (BMJ global health)
[2020, 5(1):e001983]

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Clinical characteristics on manifestation and gene mutation of a transient neonatal cyanosis: A case report.

Jing Yuan, Xue-Ping Zhu,

BACKGROUND:We analyzed the main features of an infant diagnosed with temporary neonatal cyanosis in order to strengthen our understanding of the disease. CASE SUMMARY:We report a patient diagnosed with temporary neonatal cyanosis. The main clinical characteristics, gene mutation and treatment are discussed and a review of related literature was conducted. ... Read more >>

World J Clin Cases (World journal of clinical cases)
[2020, 8(1):217-221]

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Pulmonary arteriovenous fistula diagnosed by contrast echocardiography: a case report of a daughter and a mother

Gaoyun Pan, Xinxin Dong, Jianguo Xu,

<title>Abstract</title> <p> Background Pulmonary arteriovenous fistula is a rare disease with a direct connection between the pulmonary artery and the vein, and in most cases is congenital. In a proportion of patients, it can cause hypoxemia, cyanosis and dyspnea. The golden standard for the diagnosis of PAVF is ... Read more >>

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Development of Eosinophilic Temporal Arteritis and Digital Ischemia in a Patient with Hypereosinophilic Syndrome: A Case Report.

Kayo Ishii, Takahiro Mizuuchi, Yusuke Yamamoto, Hiroaki Mori, Mayu Tago, Eri Kato, Haeru Hayashi, Koichiro Tahara, Tetsuji Sawada,

We describe a case of eosinophilic temporal arteritis in a 61-year-old woman with hypereosinophilic syndrome, who developed subcutaneous nodules in the temporal areas and digital cyanosis with small nodules on the sides of her fingers. Ultrasound revealed occlusion and corkscrew-like changes of the temporal and digital arteries, respectively. Temporal artery ... Read more >>

Intern. Med. (Internal medicine (Tokyo, Japan))
[2020, :]

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Acute Oral Toxicity of Pinnatoxin G in Mice.

Silvio Sosa, Marco Pelin, Federica Cavion, Fabienne Hervé, Philipp Hess, Aurelia Tubaro,

Pinnatoxin G (PnTx-G) is a marine cyclic imine toxin produced by the dinoflagellate Vulcanodinium rugosum, frequently detected in edible shellfish from Ingril Lagoon (France). As other pinnatoxins, to date, no human poisonings ascribed to consumption of PnTx-G contaminated seafood have been reported, despite its potent antagonism at nicotinic acetylcholine receptors ... Read more >>

Toxins (Basel) (Toxins)
[2020, 12(2):]

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The Diagnosis of Sulfated Hemoglobin (SulfHb) Secondary to Sulfur Dioxide Poisoning Using Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry (MALDI-ToF MS)-A Novel Approach to an Unusual Clinical Problem.

Suzanne Docherty, Raminta Zmuidinaite, James Coulson, Martin Besser, Ray Iles,

Sulfhemoglobinemia is a rare entity caused by irreversible sulfation of the heme moiety in haemoglobin to form sulfated haemoglobin (SulfHb) and has been caused by H2S arising from certain metabolites of drugs and bacterial infection. Clinical presentation is similar to that of methemoglobin (MetHb). Furthermore, it is often difficult to ... Read more >>

Diagnostics (Basel) (Diagnostics (Basel, Switzerland))
[2020, 10(2):]

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4q27 deletion and 7q36.1 microduplication in a patient with multiple malformations and hearing loss: a case report.

Maolan Wu, Xiangrong Zheng, Xia Wang, Guoyuan Zhang, Jian Kuang,

BACKGROUND:Chromosome deletions of the long arm of chromosome 4 in 4q syndrome are characterized by mild facial and digital dysmorphism, developmental delay, growth retardation, and skeletal and cardiac anomalies, which is regarded as an autism spectrum disorder. Moreover, some scarce reports indicate that patients with 4q interstitial deletion and 7p ... Read more >>

BMC Med Genomics (BMC medical genomics)
[2020, 13(1):31]

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Food poisoning associated methemoglobinemia: Time to wake up.

Kamal Kant Sahu, Amos Lal, Ajay Mishra, Susan George,

World J Emerg Med (World journal of emergency medicine)
[2020, 11(2):127-128]

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A bolt from the blue; A case report of an unusual asthma exacerbation.

C Moloney, A Long, G M Pastores, B J Plant, D M Murphy,

Background:We describe this case of a young gentleman presenting with acute dyspnoea on a background history of known, long-standing asthma. His dramatic presentation, notable for profound hypoxia and cyanosis, led to an unexpected additional diagnosis of type one congenital methaemoglobinaemia. Case presentation:A 26-year-old Irish gentleman was transferred urgently to the ... Read more >>

Respir Med Case Rep (Respiratory medicine case reports)
[2020, 29:100983]

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[Pulmonary arteriovenous fistulas in a pediatric patient: a case report].

Yuli T Samboni, Liliana P Tordecilla, Gilberto Acuña, Ana L Muñoz,

Pulmonary arteriovenous fistulas are congenital malformations due to anomalous direct communication between arteries and veins; the incidence is 2-3 : 100,000 inhabitants. This condition is usually asymptomatic and incidentally appearing in adult imaging findings. Transcutaneous endovascular embolization is the technique of choice for treatment. The unusual presentation in a 10-year-old ... Read more >>

Arch Argent Pediatr (Archivos argentinos de pediatria)
[2020, 118(2):e170-e173]

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Man With Cyanosis and Altered Mental Status.

Anne Runkle, Jason Block, Samir Haydar,

Ann Emerg Med (Annals of emergency medicine)
[2020, 75(1):18-48]

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A female with five chambers.

K K Sahu, A Doshi, A K Mishra, M Kranis,

Neth Heart J (Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation)
[2020, 28(3):174-175]

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Early Hours in the Development of High Altitude Pulmonary Edema- Time Course and Mechanisms.

Erik Swenson,

Clinically evident high altitude pulmonary edema (HAPE) is one of severe cyanosis, dyspnea and edema. This usually occurs within 1-2 days of ascent often with additional stresses of exercise and sleep-related hypoventilation. The earliest events in HAPE occur rapidly and progress through clinically silent and then minimally recognized problems. The ... Read more >>

J. Appl. Physiol. (Journal of applied physiology (Bethesda, Md. : 1985))
[2020, :]

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Clinical Role of Serum Interleukin-17A in the Prediction of Refractory Mycoplasma pneumoniae Pneumonia in Children.

Jiuling Zhao, Xin Ji, Yushui Wang, Xin Wang,

Background:Mycoplasma pneumoniae pneumonia (MPP) is a common community-acquired pneumonia (CAP) in children, which may become refractory MPP (RMPP) to treatment. Objective:The purpose of this study was to evaluate the clinical utility of measuring serum interleukin (IL)-17A to predict RMPP. Patients and Methods:A retrospective clinical study at a single pediatric center ... Read more >>

Infect Drug Resist (Infection and drug resistance)
[2020, 13:835-843]

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A Systematic Review of a Long-forgotten Cause of Atrial Fibrillation and Stroke: Cor Triatriatum.

Waqas Ullah, Yasar Sattar, Hiba Rauf, Sohaib Roomi, Murtaza Ishaq Shah,

Cor triatriatum is a rare congenital cardiac condition characterized by the division of one atrium into two chambers by a fibromuscular membrane, resulting in three atrial chambers. The goal of this study was to determine the associations of cor triatriatum with cyanosis, atrial fibrillation (AF), and stroke. MEDLINE (PubMed, Ovid), ... Read more >>

Cureus (Cureus)
[2019, 11(12):e6371]

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Bidirectional coronary venous return in the partial unroofed coronary sinus syndrome complicated by coronary sinus orifice atresia.

Dai Asada, Hisato Ito,

Unroofed coronary sinus syndrome complicated by coronary sinus orifice atresia is a rare congenital anomaly. There are two alternate exits for coronary venous return: unroofed coronary sinus and persistent left superior caval vein. The coronary venous direction could be bidirectional depending on the pressure balance between the left atrium and ... Read more >>

Cardiol Young (Cardiology in the young)
[2020, :1-3]

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Severe Methemoglobinemia Secondary to Ferula asafoetida Ingestion in an Infant: A Case Report.

Saleh Al-Qahtani, Sara Abusham, Ibrahim Alhelali,

Methemoglobinemia is an increase in the methemoglobin levels in the blood. Infants are more susceptible to develop secondary methemoglobinemia because of the limited activity of methemoglobin reductase B enzyme. We report a case of life-threatening methemoglobinemia secondary to ingestion of Ferula asafoetida herbal remedy in an infant who presented with ... Read more >>

Saudi J Med Med Sci (Saudi journal of medicine & medical sciences)
[2020, 8(1):56-59]

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IDDCA syndrome in a Chinese infant due to GNB5 biallelic mutations.

Mingxing Tang, Yajian Wang, Yuanyuan Xu, Wenjia Tong, Danqun Jin, Xiu-An Yang,

Herein, we present a Chinese infant with an early-onset intellectual developmental disorder with cardiac arrhythmia syndrome. A 6-month-old boy visited our hospital because of convulsions and paroxysmal cyanosis for 1 day. Mental development analysis showed that the patient had a neurodevelopmental delay. Frequent seizures occurred, and ECG monitoring demonstrated severe ... Read more >>

J. Hum. Genet. (Journal of human genetics)
[2020, :]

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Acquired Asymptomatic Blue Tongue: A Report of Exogenous Agent-associated Tongue Dyschromia and Review of Blue Tongue Etiologies.

Philip R Cohen,

This study presents the case of a man who developed a temporary and asymptomatic blue tongue. The dyschromia occurred following topical contact with gelato that contained Food, Drug, and Cosmetic (FD&C) blue dye no. 1. The etiology of a blue tongue is either congenital (in individuals with blue rubber bleb ... Read more >>

Cureus (Cureus)
[2019, 11(11):e6243]

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Anesthetic management of a surgical patient with an acute aortic dissection complicated by hemoglobin Kansas.

Takashi Kobayashi, Kenji Suzuki,

BACKGROUND:Hemoglobin Kansas (Hb Kansas) is a rare disease with cyanosis. We report a case of anesthetic management for a patient with an acute aortic dissection complicated by Hb Kansas. CASE PRESENTATION:We encountered a 62-year-old male, surgical patient with an acute aortic dissection complicated by postoperative Hb Kansas. During anesthesia, his ... Read more >>

JA Clin Rep (JA clinical reports)
[2019, 5(1):69]

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Prevalence and management of coronary artery anomalies in tetralogy of Fallot at Cheikh Zaid Hospital's Pediatric Cardiac Surgery Department in Morocco: retrospective study.

Mohamed Rida Ajaja, Amine Cheikh, Hicham Rhazali, Mustapha Bouatia, Anas Slaoui, Redouane Abouqal, Amine El Hassani, Younes Cheikhaoui,

Introduction:Tetralogy of Fallot (TOF) is one of the most common cyanogenic congenital heart defects. It represents 10% of congenital heart diseases in children. Coronary artery anomalies (CAA) have been reported in 2% to 14% of cases in patients with TOF, according to angiographic, surgical and autopsy series. Many of these ... Read more >>

Pan Afr Med J (The Pan African medical journal)
[2019, 34:157]

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Congenital methemoglobinemia: Rare presentation of cyanosis in newborns.

Ernestas Viršilas, Lina Timukienė, Arūnas Liubšys,

Methemoglobin (MetHb) is an oxidized form on hemoglobin, which is unable to bind oxygen and consequently carry it to the tissues. Normally present in small quantities (<1%) without detrimental effects, its elevation produces hypoxemia which can be profound and even lethal. Methemoglobinemia is an abnormal increase of MetHb (>3%) of ... Read more >>

Clin Pract (Clinics and practice)
[2019, 9(4):1188]

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Single Atrium and Miscarriages.

Fatos Kojqiqi, Arben Kojqiqi, Ismet Jusufi, Besnik Kojcici,

Background  A single atrium is a very rare heart condition, in which the inter atrial septum is missing. These congenital heart defects usually are surgically corrected after birth. Case Presentation  We present a successful surgical repair of a single atrium (SA) in a 27-year-old woman, who has a complete missing ... Read more >>

Thorac Cardiovasc Surg Rep (The Thoracic and cardiovascular surgeon reports)
[2020, 9(1):e4-e8]

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