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Congenital Mitral Stenosis

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Serial evaluation of cardiac biomarker NT-proBNP with speckle tracking echocardiography in a 6-year-old Golden Retriever dog with subaortic stenosis and dilated cardiomyopathy.

Woong-Bin Ro, Min-Hee Kang, Hee-Myung Park,

Vet Q (The veterinary quarterly)
[2020, 40(1):77-82]

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Late Presentation of a Congenitally Corrected Transposition of Great Arteries and Hemodynamically Balanced Ventricles Associated with a Large Ventricular Septal Defect and Severe Pulmonary Stenosis: A Case Report and a Multi-Imaging Approach.

Khaled Elenizi, Rasha Alharthi, Anthony Matta, Abdulrahman Aljuayli, Michel Galinier,

BACKGROUND Congenitally corrected transposition of great arteries (ccTGA) represents a distinct rare group of congenital heart diseases. Survival of unoperated ccTGA in the presence of large ventricular septal defect (VSD) is exceptional. Furthermore, late presentation of such patients in the absence of severe pulmonary hypertension or severe systemic right ventricle ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e920822]

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6q25.1 (TAB2) microdeletion is a risk factor for hypoplastic left heart: a case report that expands the phenotype.

Andrew Cheng, Whitney Neufeld-Kaiser, Peter H Byers, Yajuan J Liu,

INTRODUCTION:Hypoplastic left heart syndrome (HLHS) is a rare but devastating congenital heart defect (CHD) accounting for 25% of all infant deaths due to a CHD. The etiology of HLHS remains elusive, but there is increasing evidence to support a genetic cause for HLHS; in particular, this syndrome is associated with ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):137]

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Management of Late-Presenting Congenital Combined Heart Defect - Bicuspid Aortic Valve and Ventricular Septal Aneurysm.

Violeta V Groudeva, Borislav G Atzev, Dimitar G Petkov,

BACKGROUND Bicuspid aortic valve is the most common congenital heart malformation, encountered in 1-2% of the population, while interventricular septal defect and patent ductus arteriosus are the most common congenital malformations associated with bicuspid aortic valve. Although bicuspid valve can have no clinical manifestation, patients with bicuspid valve are prone ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e919766]

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Clinical impact of pathology-proven etiology of severely stenotic aortic valves on mid-term outcomes in patients undergoing surgical aortic valve replacement.

Shiro Miura, Katsumi Inoue, Hiraku Kumamaru, Takehiro Yamashita, Michiya Hanyu, Shinichi Shirai, Kenji Ando,

BACKGROUND:The use of transcatheter or surgical aortic valve replacement (AVR) for severe aortic stenosis (AS) has considerably increased in recent years. However, the association between AS etiology and mid-term clinical outcomes after surgical AVR has not been fully investigated. METHODS AND RESULTS:We retrospectively included 201 patients (mean age, 75 years; ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0229721]

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Case Report: TAVI in a Patient with Single Coronary Artery and Bicuspid Valve.

Murielle Bertin, Mohamed Aboukofa, Pierre Francois Laterre, Zuhair Yousif,

A single coronary artery is a rare congenital abnormality which consists of one coronary artery arising from the aortic trunk by a single coronary ostium and providing the perfusion of the entire myocardium. Its prevalence is approximately 0.024-0.066% of the population undergoing coronary angiography. A bicuspid aortic valve is the ... Read more >>

Case Rep Cardiol (Case reports in cardiology)
[2020, 2020:2569506]

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Pulmonary endarteritis and endocarditis complicated with septic embolism: a case report and review of the literature.

Arezoo Khosravi, Zohreh Rostami, Mohammad Javanbakht, Nematollah Jonaidi Jafari, Mohsen Sadeghi Ghahroudi, Mohammad Hassan Kalantar-Motamed, Ramezan Jafari, Behzad Einollahi,

BACKGROUND:Pulmonary endarteritis is a rare clinical phenomenon with congenital heart that can potentially lead to major complications. CASE PRESENTATION:We report a 47-year-old man with pulmonary endarteritis. This patient presented with hypertension, chest pain and a previous history of pulmonary valve disease during childhood. Also, eight-months prior, he was hospitalized with ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2020, 20(1):212]

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Coronary Arterial Abnormalities in Hypoplastic Left Heart Syndrome: Pathologic Characteristics of Archived Specimens.

Elizabeth H Stephens, Dipankar Gupta, Mark Bleiweis, Carl L Backer, Robert H Anderson, Diane E Spicer,

Palliation of patients with hypoplastic left heart syndrome remains challenging. Although coronary ischemia can be catastrophic, the prevalence and pathologies of anomalies of the coronary arteries remains unknown. We reviewed 119 specimens with the features of hypoplastic left heart syndrome, focusing our attention on the aortic root and the coronary ... Read more >>

Semin. Thorac. Cardiovasc. Surg. (Seminars in thoracic and cardiovascular surgery)
[2020, :]

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A novel TAB2 nonsense mutation (p.S149X) causing autosomal dominant congenital heart defects: a case report of a Chinese family.

Jia Chen, Huizhen Yuan, Kang Xie, Xinrong Wang, Linglong Tan, Yongyi Zou, Yan Yang, Lu Pan, Junfang Xiao, Ge Chen, Yanqiu Liu,

BACKGROUND:TAB2 is an activator of MAP 3 K7/TAK1, which is required for the IL-1 induced signal pathway. Microdeletions encompassing TAB2 have been detected in various patients with congenital heart defects (CHD), indicating that haploinsufficiency of TAB2 causes CHD. To date, seven variants within TAB2 were reported associated with CHD, only two of ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):27]

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Congenital Mitral Stenosis.

Nelson H Burbano,

J. Cardiothorac. Vasc. Anesth. (Journal of cardiothoracic and vascular anesthesia)
[2020, :]

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Congenital Supravalvar Mitral Ring - A Case Report.

Raquel Reis Soares, Leonardo Ferber, Matheus Ferber, Daniel Soares Mata,

Congenital mitral valve stenosis is a rare and severe disease, usually associated with other heart defects. The appropriate intervention depends on the site and mechanism of valvular obstruction and the aim is to avoid or delay valve replacement since it is associated with significant morbidity and mortality. Early single-stage complete ... Read more >>

Braz J Cardiovasc Surg (Brazilian Journal of Cardiovascular Surgery)
[2020, 35(1):117-119]

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Mucopolysaccharidosis type VI: case report with first neonatal presentation with ascites fetalis and rapidly progressive cardiac manifestation.

Rachel Sayuri Honjo, Evelyn Cristina Nuñez Vaca, Gabriela Nunes Leal, Deipara Monteiro Abellan, Nana Miura Ikari, Marcelo Biscegli Jatene, Ana Maria Martins, Chong Ae Kim,

BACKGROUND:The Mucopolysaccharidosis type VI (MPS VI), also known as Maroteaux-Lamy syndrome (OMIM 253200) is an autosomal recessive lysosomal disorder, caused by the deficiency of the enzyme N-acetylgalactosamine 4-sulfatase (also known as arylsulfatase B) due to mutations of the ARSB gene. Cardiologic features are well recognized, and are always present in ... Read more >>

BMC Med. Genet. (BMC medical genetics)
[2020, 21(1):37]

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Natural Coronary Bypass: A Rare Case of Aortocoronary Fistula in a Patient with Three-Vessel Disease.

Syed Arsalan Ahmed Naqvi, Syed Danish Zaidi, Owais Gul, Mudassir Iqbal Dar, Abdul Aziz,

Coronary arterial fistula (CAF) is an abnormal connection between one or both coronary arteries and a cardiac/extra-cardiac chamber or another vessel. Aortocoronary fistula is a rare type of CAF, which involves an anomalous connection between coronary arteries and any segment of aorta. The following case report describes the case of ... Read more >>

Cureus (Cureus)
[2020, 12(2):]

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Pathologic Characteristics of 119 Archived Specimens Showing the Phenotypic Features of Hypoplastic Left Heart Syndrome.

Elizabeth H Stephens, Dipankar Gupta, Mark Bleiweis, Carl L Backer, Robert H Anderson, Diane E Spicer,

To assess the phenotypic variations found among hearts diagnosed at autopsy with hypoplastic left heart syndrome, with attention to implications related to this syndrome as an acquired disease of fetal life, rather than being the consequence of abnormal embryogenesis. We assessed 119 specimens, from 2 archives, diagnosed initially as representing ... Read more >>

Semin. Thorac. Cardiovasc. Surg. (Seminars in thoracic and cardiovascular surgery)
[2020, :]

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The Financial Impact of Genetic Diseases in a Pediatric Accountable Care Organization.

Katherine E Miller, Richard Hoyt, Steve Rust, Rachel Doerschuk, Yungui Huang, Simon M Lin,

Background: Previous studies revealed patients with genetic disease have more frequent and longer hospitalizations and therefore higher healthcare costs. To understand the financial impact of genetic disease on a pediatric accountable care organization (ACO), we analyzed medical claims from 2014 provided by Partners for Kids, an ACO in partnership with ... Read more >>

Front Public Health (Frontiers in Public Health)
[2020, 8:58]

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Myhre Syndrome Associated With Dunbar Syndrome and Urinary Tract Abnormalities: A Case Report.

Zofia Varenyiova, Gabriela Hrckova, Denisa Ilencikova, Ludmila Podracka,

Myhre syndrome is a rare condition caused by a mutation in the SMAD4 gene, which leads to a defective TGF-β/BMP signaling, resulting in the proliferation of abnormal fibrous tissues. Clinically, patients with Myhre syndrome manifest with defects of connective tissue (skin, muscles, joints), and cardiovascular and neurological impairment. In our ... Read more >>

Front Pediatr (Frontiers in Pediatrics)
[2020, 8:72]

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Aberrant right coronary artery in a grown up congenital cardiac patient, successfully treated 46 years earlier with a double Starr-Edwards silastic ball valve replacement: a case report.

Andrea Ponsiglione, Gianrico Spagnuolo, Gabriella Spagnuolo, Arnaldo Stanzione, Carmela Nappi, Serena Dell'Aversana, Antonio Spagnuolo, Alberto Cuocolo, Massimo Imbriaco,

BACKGROUND:The Starr-Edwards ball valve prosthesis was successfully introduced in 1961-62 and largely used for aortic and mitral valve replacement. Even if Starr-Edwards valves have been widely replaced in clinical practice by other mechanical valves, they define a standard concerning long-term durability. CASE PRESENTATION:We describe the case of a 55-year-old man ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):37]

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Risk factors for low cardiac output syndrome in children with congenital heart disease undergoing cardiac surgery: a retrospective cohort study.

Xinwei Du, Hao Chen, Xiaoqi Song, Shunmin Wang, Zedong Hao, Lifeng Yin, Zhaohui Lu,

BACKGROUND:Low cardiac output syndrome (LCOS) is an important complication of cardiac surgery. It is associated with increased morbidity and mortality. The incidence of LCOS after surgery is high in patients with congenital heart disease (CHD). Therefore, determining the risk factors of LCOS has clinical significance for the management of CHD. ... Read more >>

BMC Pediatr (BMC pediatrics)
[2020, 20(1):87]

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A rare finding of giant accessory mitral valve tissue: a case report.

Joseph Okafor, Gajen Sunthar Kanaganayagam, Ketna Patel,

Background:Accessory mitral valve tissue (AMVT) is a rare anomaly that can be detected in the first decade. It is associated with other congenital cardiac abnormalities, such as ventricular septal defect. When detected in adulthood, it is usually an incidental finding on echocardiography. Symptomatic individuals can present with breathlessness, syncope, and ... Read more >>

Eur Heart J Case Rep (European heart journal. Case reports)
[2020, 4(1):1-4]

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The Brazilian Contributions to Congenital Cardiac Surgery.

Elizabeth H. Stephens, Joseph A. Dearani,

Braz J Cardiovasc Surg (Brazilian Journal of Cardiovascular Surgery)
[2020, 35(1):I-III]

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Adult ALCAPA: from histological picture to clinical features.

Hiroshi Kubota, Hidehito Endo, Hikaru Ishii, Hiroshi Tsuchiya, Yusuke Inaba, Katsunari Terakawa, Yu Takahashi, Mio Noma, Kazuya Takemoto, Seiichi Taniai, Konomi Sakata, Kyoko Soejima, Hiroaki Shimoyamada, Hiroshi Kamma, Hayato Kawakami, Yukihiro Kaneko, Satoru Hirono, Daisuke Izumi, Kazuyuki Ozaki, Tohru Minamino, Hideaki Yoshino, Kenichi Sudo,

BACKGROUND:Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital coronary anomaly that results in high mortality if left untreated. Our aim was to extend our knowledge of the histological, angiographic, and clinical characteristics of ALCAPA in order to deepen our understanding of this rare entity. CASE ... Read more >>

J Cardiothorac Surg (Journal of cardiothoracic surgery)
[2020, 15(1):14]

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Development of Spontaneous Echocardiographic Contrast After Transarterial Occlusion of a Patent Ductus Arteriosus in an Adult Dog With Concurrent Pulmonary Hypertension.

Randolph L Winter, Julia D Remaks, Daniel K Newhard,

An 8-year-old intact female Chihuahua was presented for evaluation and possible occlusion of a previously diagnosed patent ductus arteriosus (PDA). Transthoracic echocardiography revealed left ventricular and left atrial enlargement, enlargement of the main pulmonary artery, and a PDA with bidirectional shunting. Tricuspid regurgitant velocities suggested moderate pulmonary hypertension. The PDA ... Read more >>

Front Vet Sci (Frontiers in Veterinary Science)
[2020, 7:103]

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Characteristics of Patent Ductus Arteriosus in Congenital Rubella Syndrome.

Michiko Toizumi, Cam Giang T Do, Hideki Motomura, Tin N Do, Hirofumi Fukunaga, Makiko Iijima, Nhan Nt Le, Hung Thanh Nguyen, Hiroyuki Moriuchi, Lay-Myint Yoshida,

This study investigated the characteristics of congenital rubella syndrome (CRS)-associated cardiac complications, particularly patent ductus arteriosus (PDA). We reviewed the medical records of patients with CRS who were admitted to the Children's Hospital 1 in Vietnam between December 2010 and December 2012, and patients with CRS who underwent PDA transcatheter ... Read more >>

Sci Rep (Scientific reports)
[2019, 9(1):17105]

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Tale of 2 Orifices.

Alan F Vainrib, Didier F Loulmet, Mathew R Williams, Muhamed Saric,

Circ Cardiovasc Imaging (Circulation. Cardiovascular imaging)
[2019, 12(1):e008372]

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Spectrum of heart diseases in children presenting to a paediatric cardiac echocardiography clinic in the Lake Zone of Tanzania: a 7 years overview.

Antke Zuechner, Tumaini Mhada, Naizihijwa G Majani, Godwin G Sharau, William Mahalu, Matthias W Freund,

BACKGROUND:Congenital heart diseases (CHD) are among the most common congenital malformations. It is estimated that the incidence of CHD is constant worldwide, but data are rare for most African countries including Tanzania. Even less data are available on the prevalence of acquired heart diseases (AHD) in African children. Rheumatic heart ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2019, 19(1):291]

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