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Use of Complementary and Alternative Medicine in Children With Tourette Syndrome.

Himadri Patel, KieuHanh Nguyen, Erik Lehman, Gayatra Mainali, Laura Duda, Debra Byler, Ashutosh Kumar,

INTRODUCTION:Tourette syndrome is a neuropsychiatric condition defined by motor and phonic tics with onset in childhood. Many families have concerns regarding potential side effects of pharmacologic treatments, and often have difficulty accessing comprehensive behavioral intervention for tics. Patients and caregivers may turn to complementary and alternative medicine (CAM) as they ... Read more >>

J. Child Neurol. (Journal of child neurology)
[2020, :883073820913670]

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Pediatric APS: State of the Art.

Arzu Soybilgic, Tadej Avcin,

PURPOSE OF REVIEW:The purpose of this report is to review recent research findings on APS in children and neonates. RECENT FINDINGS:European evidence-based recommendations for diagnosis and treatment of pediatric APS has recently been published by the SHARE Initiative. Recent studies have shown a high prevalence of non-thrombotic manifestations in children ... Read more >>

Curr Rheumatol Rep (Current rheumatology reports)
[2020, 22(3):9]

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Alterations in the Nervous System and Gut Microbiota after β-Hemolytic Streptococcus Group A Infection-Characteristics and Diagnostic Criteria of PANDAS Recognition.

Jacek Baj, Elżbieta Sitarz, Alicja Forma, Katarzyna Wróblewska, Hanna Karakuła-Juchnowicz,

The objective of this paper is to review and summarize conclusions from the available literature regarding Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS). The authors have independently reviewed articles from 1977 onwards, primarily focusing on the etiopathology, symptoms, differentiation between similar psychiatric conditions, immunological reactions, alterations in the ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(4):]

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Longitudinal relationships between maternal depressive/anxious symptoms and children’s tics

Tomoko Yagi, Shuntaro Ando, Satoshi Usami, Syudo Yamasaki, Masaya Morita, Tomoki Kiyono, Noriyuki Hayashi, Kaori Endo, Yudai Iijima, Yuko Morimoto, Sho Kanata, Shinya Fujikawa, Shinsuke Koike, Yukiko Kano, Mariko Hiraiwa-Hasegawa, Atsushi Nishida, Kiyoto Kasai,

<title>Abstract</title> <p> Background Previous studies have revealed an association between maternal depressive/anxious symptoms and children’s tics. However, the longitudinal relationship between these symptoms remains unclear. We examined the longitudinal relationships between maternal depressive/anxious symptoms and children’s tics across early adolescence in a population-based sample. Methods Participants were 3,171 ... Read more >>

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Simultaneous Occurrence of Sydenham Chorea with Erythema Marginatum: A Case of Rheumatic Fever.

Temesgen Tsega Desta, Mulugeta Naizgi,

Background:Rheumatic fever continues to be a major public health problem in the developing world, being responsible for many morbidities and mortalities. Were it not for its serious effects on the cardiovascular system, and to some extent on the central nervous system, the disease might not have significant consequences. The central nervous system involvement is ... Read more >>

Pediatric Health Med Ther (Pediatric health, medicine and therapeutics)
[2020, 11:55-58]

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Pediatric autoimmune encephalitis: Recognition and diagnosis.

Marienke A A M de Bruijn, Arlette L Bruijstens, Anna E M Bastiaansen, Agnes van Sonderen, Marco W J Schreurs, Peter A E Sillevis Smitt, Rogier Q Hintzen, Rinze F Neuteboom, Maarten J Titulaer, ,

OBJECTIVE:The aims of this study were (1) to describe the incidence of autoimmune encephalitis (AIE) and acute disseminated encephalomyelitis (ADEM) in children, (2) to validate the currently used clinical criteria to diagnose AIE, and (3) to describe pitfalls in the diagnosis of pediatric autoimmune (AI) and inflammatory neurologic disorders. METHODS:This ... Read more >>

Neurol Neuroimmunol Neuroinflamm (Neurology(R) neuroimmunology & neuroinflammation)
[2020, 7(3):]

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Instrumented assessment of motor function in dyskinetic cerebral palsy: a systematic review.

Helga Haberfehlner, Marije Goudriaan, Laura A Bonouvrié, Elise P Jansma, Jaap Harlaar, R Jeroen Vermeulen, Marjolein M van der Krogt, Annemieke I Buizer,

BACKGROUND:In this systematic review we investigate which instrumented measurements are available to assess motor impairments, related activity limitations and participation restrictions in children and young adults with dyskinetic cerebral palsy. We aim to classify these instrumented measurements using the categories of the international classification of functioning, disability and health for ... Read more >>

J Neuroeng Rehabil (Journal of neuroengineering and rehabilitation)
[2020, 17(1):39]

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Preliminary data on prednisone effectiveness in children with Sydenham chorea.

Elena Favaretto, Giulia Gortani, Gabriele Simonini, Serena Pastore, Alberto Di Mascio, Rolando Cimaz, Andrea Taddio,

The objective of the study is to evaluate the efficacy of corticosteroids in Sydenham chorea. This is a retrospective observational study. Clinical information of children with Sydenham chorea were collected. Outcome of Sydenham chorea was evaluated in consideration of presence or absence of corticosteroid therapy. Thirty patients were enrolled. A ... Read more >>

Eur. J. Pediatr. (European journal of pediatrics)
[2020, :]

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Acute Rheumatic Fever: A Disease of the Past?

Robert L Myette,

Introduction. Acute rheumatic fever (ARF) is a manifestation of the nonsuppurative sequelae of Streptococcus pyogenes infection. Herein, two cases of ARF are presented to highlight that this disease is present in urban cities, can be diagnosed in otherwise healthy children, and that its diagnosis may be challenging, or marred with ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2020, 2020:1470697]

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Interventions for tic disorders: An updated overview of systematic reviews and meta analyses.

Chunsong Yang, Xiao Cheng, Qiyunrui Zhang, Dan Yu, Jiayuan Li, Lingli Zhang,

To conduct an updated overview of systematic reviews (SRs) summarizing the efficacy and safety of various strategies used to treat tic disorders (TDs) in children. We searched the Cochrane Library, PubMed, EMBASE, and relevant reference lists for articles published between the search deadline from our last overview and April 2019 ... Read more >>

Psychiatry Res (Psychiatry research)
[2020, 287:112905]

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Low enrollment and high treatment success in children with drug-resistant tuberculosis in Ethiopia: A ten years national retrospective cohort study.

Habteyes Hailu Tola, Kourosh Holakouie-Naieni, Mohammad Ali Mansournia, Mehdi Yaseri, Ephrem Tesfaye, Zemedu Mahamed, Million Molla Sisay,

BACKGROUND:Limited evidence exists on the treatment outcome and factors that are associated with the duration from the initiation of treatment to death or treatment failure in children with drug resistant tuberculosis (DR-TB). Thus, we aimed to determine the proportion of treatment enrollment, status of treatment outcome and determine factors that ... Read more >>

PLoS ONE (PloS one)
[2020, 15(2):e0229284]

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Efficacy of Parent-Delivered, Home-Based Therapy for Tics.

Harvey S Singer, Shelley McDermott, Lisa Ferenc, Mathew Specht, E Mark Mahone,

BACKGROUND:Although behavioral therapy is an effective approach to reduce tics in children and adults, there is an insufficient availability and accessibility of behavioral therapy in the community. OBJECTIVE:The goal of the study was to test the clinical efficacy of home-based, parent-provided behavioral therapy in children with Tourette syndrome aged seven ... Read more >>

Pediatr. Neurol. (Pediatric neurology)
[2020, :]

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Intravenous Immunoglobulin Treatment Did Not Improve Tics in a Patient With Gilles de la Tourette Syndrome and Intrathecal Antibody Synthesis.

Natalia Szejko, Carolin Fremer, Kurt-Wolfram Sühs, Pedro Macul Ferreira de Barros, Kirsten R Müller-Vahl,

Gilles de la Tourette syndrome (GTS) is a neuropsychiatric disorder characterized by motor and vocal tics. There are several hypotheses as to the cause of the disease. One of which suggests that the immune system is involved in the pathophysiology of GTS. Here, we present a 40-year-old female patient with ... Read more >>

Front Neurol (Frontiers in Neurology)
[2020, 11:110]

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Tourette's disorder in children and adolescents.

Donald E Greydanus, Julia Tullio,

Tourette's disorder (TD) is one of the five American Psychiatric Association's 2013 Diagnostic and Statistical Manual of Mental Disorders (DSM-5) classifications of tic disorders. Eponymously linked with the noted 19th century French physician, Gilles de la Tourette [1857-1904], this disorder is identified in 0.3% to 0.7% of the population. It ... Read more >>

Transl Pediatr (Translational pediatrics)
[2020, 9(Suppl 1):S94-S103]

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Human health risk assessment of elevated and variable iron and manganese intake with arsenic-safe groundwater in Jashore, Bangladesh.

Gopal Chandra Ghosh, Md. Jahed Hassan Khan, Tapos Kumar Chakraborty, Samina Zaman, A. H. M. Enamul Kabir, Hiroaki Tanaka,

Groundwater through hand-operated tubewell (a type of water well) tapping is the main source of drinking water in Bangladesh. This study investigated iron and manganese concentration in groundwater across Jashore district–one of the worst arsenic contaminated area in Bangladesh. One working tubewell that had been tested previously for arsenic and ... Read more >>

Sci Rep (Scientific reports)
[2020, 10:]

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Multiphasic acute disseminated encephalomyelitis and differential with early onset multiple sclerosis.

Arla Cinderella Stokes Brackett, Otto Jesus Hernández-Fustes, Carlos Arteaga Rodríguez, Olga Judith Hernandez Fustes,

Multiple sclerosis is considered the most frequent demyelinating disorder of the Central Nervous System (CNS) among young adults, yet is very rare before 10 years old. Acute disseminated encephalomyelitis is a monophasic, polysymptomatic disorder that involves the CNS white matter with demyelinating lesions, which usually occurs after systemic viral infections. ... Read more >>

Intractable Rare Dis Res (Intractable & rare diseases research)
[2020, 9(1):61-63]

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A civil society view of rare disease public policy in six Latin American countries.

Mo Mayrides, Eva Maria Ruiz de Castilla, Silvina Szelepski,

Patients with rare diseases across the world struggle to access timely diagnosis and state-of-the-art treatment and management of their conditions. Several recently published reviews highlight the importance of country efforts to address rare diseases and orphan drugs policy comprehensively. However, many of these reviews lack depth and detail at the ... Read more >>

Orphanet J Rare Dis (Orphanet journal of rare diseases)
[2020, 15(1):60]

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Endothelial Dysfunction and the Effect of Arginine and Citrulline Supplementation in Children and Adolescents With Mitochondrial Diseases.

Fatma Al Jasmi, Nuha Al Zaabi, Khalid Al-Thihli, Amal M Al Teneiji, Jozef Hertecant, Ayman W El-Hattab,

Background:In addition to the reduced energy production, characteristic of mitochondrial disorders, nitric oxide (NO) deficiency can occur as well. The NO produced by vascular endothelial cells relaxes vascular smooth muscles, resulting in vasodilation that maintains the patency of small blood vessels and promotes blood flow through microvasculature. Endothelial dysfunction due ... Read more >>

J Cent Nerv Syst Dis (Journal of central nervous system disease)
[2020, 12:1179573520909377]

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Effectiveness of a modified comprehensive behavioral intervention for tics for children and adolescents with tourette's syndrome: A randomized controlled trial.

Chia-Wen Chen, Huei-Shyong Wang, Hsiu-Ju Chang, Chang-Wei Hsueh,

AIM:To evaluate the effectiveness of a modified four-session Comprehensive Behavioral Intervention for Tics programme for decreasing tics in children and adolescents with Tourette's syndrome. BACKGROUND:Comprehensive Behavioral Intervention for Tics programme has been shown to decrease tic severity. However, the lack of behaviour therapists in countries, such as in Taiwan, may ... Read more >>

J Adv Nurs (Journal of advanced nursing)
[2020, 76(3):903-915]

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Protocol for the Process Evaluation of the Online Remote Behavioural Intervention for Tics (ORBIT) randomized controlled trial for children and young people.

K Khan, C Hollis, C L Hall, E B Davies, D Mataix-Cols, P Andrén, T Murphy, B J Brown, E Murray, C Glazebrook,

BACKGROUND:Process evaluations are an important component in the interpretation and understanding of outcomes in trials. The Online Remote Behavioural Intervention for Tics (ORBIT) study is a randomized controlled trial evaluating the effectiveness of an Internet-delivered behavioural intervention (called BIP TIC) compared to an Internet-delivered education programme aimed at children and ... Read more >>

Trials (Trials)
[2020, 21(1):6]

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Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient.

Tania Cellucci, Heather Van Mater, Francesc Graus, Eyal Muscal, William Gallentine, Marisa S Klein-Gitelman, Susanne M Benseler, Jennifer Frankovich, Mark P Gorman, Keith Van Haren, Josep Dalmau, Russell C Dale,

OBJECTIVE:Autoimmune encephalitis (AE) is an important and treatable cause of acute encephalitis. Diagnosis of AE in a developing child is challenging because of overlap in clinical presentations with other diseases and complexity of normal behavior changes. Existing diagnostic criteria for adult AE require modification to be applied to children, who ... Read more >>

Neurol Neuroimmunol Neuroinflamm (Neurology(R) neuroimmunology & neuroinflammation)
[2020, 7(2):]

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Is botulinum toxin effective and safe for motor and phonic tics in patients affected by Tourette syndrome? A Cochrane Review summary with commentary.

Antimo Moretti,

Dev Med Child Neurol (Developmental medicine and child neurology)
[2020, 62(3):274-276]

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A graph theory study of resting-state functional connectivity in children with Tourette syndrome.

Thaïra J C Openneer, Jan-Bernard C Marsman, Dennis van der Meer, Natalie J Forde, Sophie E A Akkermans, Jilly Naaijen, Jan K Buitelaar, Andrea Dietrich, Pieter J Hoekstra,

Little is known about the brain's functional organization during resting-state in children with Tourette syndrome (TS). We aimed to investigate this with a specific focus on the role of comorbid attention-deficit/hyperactivity disorder (ADHD). We applied graph theoretical analysis to resting-state functional magnetic resonance imaging data of 109 8-to-12-year-old children with ... Read more >>

Cortex (Cortex; a journal devoted to the study of the nervous system and behavior)
[2020, 126:63-72]

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Psychosocial stress and longitudinally measured gestational weight gain throughout pregnancy: The Ulm SPATZ Health Study.

S Braig, C A Logan, F Reister, D Rothenbacher, J Genuneit,

Psychosocial stress is thought to influence gestational weight gain (GWG), but results are inconsistent. We investigated the relationship of questionnaire-based maternal stress and related constructs assessed at childbirth with maternal weight measured throughout pregnancy. Data were derived from the Ulm SPATZ Health Study, a birth cohort recruited from the general ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):1996]

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[Clinical characteristics of children with Tourette's Syndrome].

Péter Nagy, Emese Bognár, Luca Farkas, Eszter Kenézlöi, Péter Vida, Júlia Gádoros, Zsanett Tárnok,

INTRODUCTION:Tourette Syndrome (TS) is a neurodevelopmental disorder presenting with motor and vocal tics. Although TS influences the everyday life of children, we only have fragmented knowledge on the topic of the developmental and comorbidity profile, symptom severity and genetical/environmental background. The aim of this article is to present the demographical ... Read more >>

Psychiatr Hung (Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata)
[2020, 35(1):37-45]

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