Makoto Suzuki, Takeshi Igawa, Nanoka Suzuki, Hajime Ogino, Haruki Ochi,
MicroPubl Biol (microPublication biology)
[2020, 2020:]
Cited: 0 times
Jeremy J Grubbs, Alexander M van der Linden, David M Raizen,
(microPublication biology)
[2020, 2020:]
Cited: 0 times
Sarah VanDiepenbos, Györgyi Csankovszki,
(microPublication biology)
[2020, 2020:]
Cited: 0 times
MicroPubl Biol (microPublication biology)
[2019, 2019:]
Cited: 2 times
MicroPubl Biol (microPublication biology)
[2019, 2019:]
Cited: 0 times
MicroPubl Biol (microPublication biology)
[2019, 2019:]
Cited: 2 times
Min-Wu Chao, Tony Eight Lin, Wei-Chun HuangFu, Chao-Di Chang, Huang-Ju Tu, Liang-Chieh Chen, Shih-Chung Yen, Tzu-Ying Sung, Wei-Jan Huang, Chia-Ron Yang, Shiow-Lin Pan, Kai-Cheng Hsu,
The STE20 kinase family is a complex signalling cascade that regulates cytoskeletal organisation and modulates the stress response. This signalling cascade includes various kinase mediators, such as TAOK1 and MAP4K5. The dysregulation of the STE20 kinase pathway is linked with cancer malignancy. A small-molecule inhibitor targeting the STE20 kinase pathway ... Read more >>
J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2021, 36(1):98-108]
Cited: 0 times
Saima Javed, Zulfiqar Ali Mirani, Zaid Ahmed Pirzada,
Biofilm is an important virulent marker attributed to the development of urinary tract infections (UTIs) by uropathogenic E. coli (UPEC). Drug-resistant and biofilm-producing UPEC are highly problematic causing catheter-associated or recurrent UTIs with significant morbidity and mortality. The aim of the current study was to investigate the prevalence of biofilm ... Read more >>
Libyan J Med (The Libyan journal of medicine)
[2021, 16(1):1845444]
Cited: 0 times
Rania Hammami, Fatma Zouari, Mohamed Aymen Ben Abdessalem, Awatef Sassi, Tarek Ellouze, Amine Bahloul, Souad Mallek, Faten Triki, Abdallah Mahdhaoui, Gouider Jeridi, Leila Abid, Selma Charfeddine, Samir Kammoun, Jihen Jdidi,
The distal radial approach (DRA) is suggested to have benefits over the conventional radial approach (CRA) in terms of local complications and comfort of both patient and operator. Therefore, we aimed to compare the feasibility and safety of DRA and CRA in a real life population. We conducted a prospective, ... Read more >>
Libyan J Med (The Libyan journal of medicine)
[2021, 16(1):1830600]
Cited: 0 times
Francisco Javier Carrasco-Sánchez, Mª Dolores López-Carmona, Francisco Javier Martínez-Marcos, Luis M Pérez-Belmonte, Alicia Hidalgo-Jiménez, Verónica Buonaiuto, Carmen Suárez Fernández, Santiago Jesús Freire Castro, Davide Luordo, Paula Maria Pesqueira Fontan, Julio César Blázquez Encinar, Jeffrey Oskar Magallanes Gamboa, Andrés de la Peña Fernández, José David Torres Peña, Joaquim Fernández Solà, Jose Javier Napal Lecumberri, Francisco Amorós Martínez, María Esther Guisado Espartero, Carlos Jorge Ripper, Raquel Gómez Méndez, Natalia Vicente López, Berta Román Bernal, María Gloria Rojano Rivero, José Manuel Ramos Rincón, Ricardo Gómez Huelgas, ,
BACKGROUND:Hyperglycaemia has emerged as an important risk factor for death in coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the association between blood glucose (BG) levels and in-hospital mortality in non-critically patients hospitalized with COVID-19. METHODS:This is a retrospective multi-centre study involving patients hospitalized in Spain. ... Read more >>
Ann Med (Annals of medicine)
[2021, 53(1):103-116]
Cited: 0 times
Samir Mehndiratta, Mei-Chuan Chen, Yuh-Hsuan Chao, Cheng-Hsin Lee, Jing-Ping Liou, Mei-Jung Lai, Hsueh-Yun Lee,
A series of 3-subsituted quinolinehydroxamic acids has been synthesised and evaluated for their effect on human lung cancer cell line (A549), human colorectal cancer cell line (HCT116) and HDAC isoforms 1, 2, 6, and 8. The results indicated that substitution at C3 of quinoline is favoured for HDAC6 selectivity. Two ... Read more >>
J Enzyme Inhib Med Chem (Journal of enzyme inhibition and medicinal chemistry)
[2021, 36(1):74-84]
Cited: 0 times
Qingfang Zeng, Cairong Luo, Junlae Cho, Donna Lai, Xiangchun Shen, Xiaoyan Zhang, Wei Zhou,
Tryptanthrin is an indole quinazoline alkaloid from the indigo-bearing plants, such as Isatis indigotica Fort. Typically, this natural compound shows a variety of pharmacological activities such as antitumor, antibacterial, anti-inflammatory and antioxidant effects. This study was conducted to assess the antitumor activity of tryptanthrin in breast cancer models both in ... Read more >>
Acta Pharm (Acta pharmaceutica (Zagreb, Croatia))
[2021, 71(2):245-266]
Cited: 0 times
Shuaishuai Huang, Gulimire Tuergong, Hangjie Zhu, Xue Wang, Guobin Weng, Yu Ren,
Renal cell carcinoma (RCC) is generally acknowledged as the most resistant primary malignancy unresponsive to conventional radiotherapy and chemotherapy treatments. Norcantharidin (NCTD), a therapeutic compound derived from medicinal plants, has been shown to trigger apoptosis, as well as antimetastatic and antioxidant activities in several tumor cells. However, NCTD's mechanism of ... Read more >>
Acta Pharm (Acta pharmaceutica (Zagreb, Croatia))
[2021, 71(2):267-278]
Cited: 0 times
Chao-Chao Yu, Chuan He, Yan-Jun Du, Shan Gao, Yuan-Fang Lin, Shu-Qin Wang, Li Wang, Jia Wang, Xue-Song Wang, Tao Jiang, Li-Hong Kong,
Acupuncture can reduce cognitive deficits in Alzheimer's disease. However, whether electroacupuncture can prevent or alleviate the cognitive deficits in animal models of aging remains poorly understood. Studies have shown that disordered epigenetic modifications play a critical role in age-related cognitive decline. Therefore, we hypothesized that preventive electroacupuncture might improve cognitive ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):916-923]
Cited: 0 times
Ming-Yu Shi, Cheng-Cheng Ma, Fang-Fang Chen, Xiao-Yu Zhou, Xue Li, Chuan-Xi Tang, Lin Zhang, Dian-Shuai Gao,
Glial cell line-derived neurotrophic factor (GDNF) plays an important role in the protection of dopaminergic neurons, but there are few reports of the relationship between GDNF and its precursors (α-pro-GDNF and β-pro-GDNF) and cognitive impairment in Parkinson's disease. This study aimed to investigate the relationship between the serum levels of ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):885-892]
Cited: 0 times
Bing-Qian Cao, Feng Tan, Jie Zhan, Peng-Hui Lai,
The inflammatory response after cerebral ischemia/reperfusion is an important cause of neurological damage and repair. After cerebral ischemia/reperfusion, microglia are activated, and a large number of circulating inflammatory cells infiltrate the affected area. This leads to the secretion of inflammatory mediators and an inflammatory cascade that eventually causes secondary brain ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):944-954]
Cited: 0 times
Yansheng Liu, Jia-Xin Xie, Fang Niu, Zhexi Xu, Pengju Tan, Caihong Shen, Hongkun Gao, Song Liu, Zhengwen Ma, Kwok-Fai So, Wutian Wu, Chen Chen, Sujuan Gao, Xiao-Ming Xu, Hui Zhu,
Although a large number of trials in the SCI field have been conducted, few proven gains have been realized for patients. In the present study, we determined the efficacy of a novel combination treatment involving surgical intervention and long-term weight-bearing walking training in spinal cord injury (SCI) subjects clinically diagnosed ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):820-829]
Cited: 0 times
Guo-Xiong Cheng, Shu-Bin Yin, Ying-Hao Yang, Yuan-Hu Hu, Chih-Yang Huang, Qian-Ming Yao, Wei-Jen Ting,
Deep brain stimulation of the bilateral subthalamic nucleus (STN) is a therapeutic option for patients with Parkinson's disease (PD) in whom medical therapies have been ineffective. This retrospective cohort study analyzed the motor function of 27 patients with advanced PD, from the First Affiliated Hospital of Guangzhou Medical University, China, ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):905-909]
Cited: 0 times
Jian-Zhu Bo, Ling Xue, Shuang Li, Jing-Wen Yin, Zheng-Yao Li, Xi Wang, Jun-Feng Wang, Yan-Shu Zhang,
Although exogenous D-serine has been applied as a neural regulatory intervention in many studies, the role played by D-serine in hippocampal injuries caused by lead exposure remains poorly understood. Rat models of chronic lead exposure were established through the administration of 0.05% lead acetate for 8 weeks. Simultaneously, rats were ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):836-841]
Cited: 0 times
Xue-Mei Zhang, Yuan-Jiao Ouyang, Bing-Qian Yu, Wei Li, Mei-Yu Yu, Jin-Yue Li, Zhuo-Min Jiao, Dan Yang, Na Li, Ying Shi, Yun-Yun Xu, Zhi-Jun He, Duo Wang, Hui Yue, Jin Fu,
Dental pulp stem cells are dental pulp-derived mesenchymal stem cells that originate from the neural crest. They exhibit greater potential for the treatment of nervous system diseases than other types of stem cells because of their neurogenic differentiation capability and their ability to secrete multiple neurotrophic factors. Few studies have ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):893-898]
Cited: 0 times
Xiao-Qing Cheng, Wen-Jing Xu, Xiao Ding, Gong-Hai Han, Shuai Wei, Ping Liu, Hao-Ye Meng, Ai-Jia Shang, Yu Wang, Ai-Yuan Wang,
In our previous study, we investigated the dynamic expression of cytokines in the distal nerve stumps after peripheral nerve injury using microarray analysis, which can characterize the dynamic expression of proteins. In the present study, we used a rat model of right sciatic nerve transection to examine changes in the ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):878-884]
Cited: 0 times
Encouraging results have been reported for the use of transcranial magnetic stimulation-based nerve stimulation in studies of the mechanisms of neurological regulation, nerve injury repair, and nerve localization. However, to date, there are only a few reviews on the use of transcranial magnetic stimulation for diabetic neuropathy. Patients with diabetic ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):955-962]
Cited: 0 times
Zhong-Ya Wei, Hui-Lin Qu, Yu-Juan Dai, Qian Wang, Zhuo-Min Ling, Wen-Feng Su, Ya-Yu Zhao, Wei-Xing Shen, Gang Chen,
Pannexin 1 (Panx 1), as a large-pore membrane channel, is highly permeable to ATP and other signaling molecules. Previous studies have demonstrated the expression of Panx 1 in the nervous system, including astrocytes, microglia, and neurons. However, the distribution and function of Panx 1 in the peripheral nervous system are ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):899-904]
Cited: 0 times
Sanaa K Bardaweel, Rima Hajjo, Dima A Sabbah,
Recently, an outbreak of a fatal coronavirus, SARS-CoV-2, has emerged from China and is rapidly spreading worldwide. Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis. An integrative bioinformatics approach starting with mining the biomedical literature for high confidence DPP4-protein/gene associations followed by functional analysis ... Read more >>
Acta Pharm (Acta pharmaceutica (Zagreb, Croatia))
[2021, 71(2):175-184]
Cited: 0 times
Yi-Hao Deng, Ling-Ling Dong, Yong-Jie Zhang, Xiao-Ming Zhao, Hong-Yun He,
Autophagy is crucial for maintaining cellular homeostasis, and can be activated after ischemic stroke. It also participates in nerve injury and repair. The purpose of this study was to investigate whether an enriched environment has neuroprotective effects through affecting autophagy. A Sprague-Dawley rat model of transient ischemic stroke was prepared ... Read more >>
Neural Regen Res (Neural regeneration research)
[2021, 16(5):813-819]
Cited: 0 times