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Cerebral Venous Thrombosis

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Case report: postpartum cerebral venous thrombosis misdiagnosed as postdural puncture headache.

Mi K Oh, Jae H Ryu, Woo J Jeon, Chang W Lee, Sang Y Cho,

BACKGROUND:Cerebral venous thrombosis can be a fatal complication of the postpartum period. Pregnancy is known to be a risk factor for thromboembolism in itself. CASE PRESENTATION:A normal spontaneous vaginal delivery was planned for a 20-year-old primigravida patient with patient-controlled epidural analgesia. Next morning, the patient complained of an occipital headache. ... Read more >>

BMC Anesthesiol (BMC anesthesiology)
[2020, 20(1):80]

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Prediction of deep vein thrombosis by ultrasonography and D-dimer in Asian patients with ischemic stroke

Bum Joon Kim, Sang Hee Ha, Yeon-Jung Kim, Sung Hyuk Heo, Dae-il Chang,

<title>Abstract</title> <p> Background: Deep vein thrombosis (DVT) is an important complication of ischemic stroke, although the incidence of DVT is regarded as being lower in Asian than in non-Asian patients. Here, we investigated the incidence and factors associated with DVT in Asian patients with ischemic stroke. Methods: Acute ... Read more >>

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Molecular Analysis of Prothrombotic Gene Variants in Venous Thrombosis: A Potential Role for Sex and Thrombotic Localization.

Gustavo Cernera, Alessandro Di Minno, Felice Amato, Ausilia Elce, Renato Liguori, Dario Bruzzese, Antonella Miriam Di Lullo, Giuseppe Castaldo, Federica Zarrilli, Marika Comegna,

Background: Requests to test for thrombophilia in the clinical context are often not evidence-based. Aim: To define the role of a series of prothrombotic gene variants in a large population of patients with different venous thromboembolic diseases. Methods: We studied Factor V Leiden (FVL), FVR2, FII G20210A, Methylenetetrahydrofolate reductase (MTHFR) ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(4):]

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Cerebral Venous Thrombosis: An Unexpected Complication with Cerebrospinal Fluid Leaks after a Fall in a Patient with Spinocerebellar Ataxia Type 6.

Yuki Yamamoto, Nobuaki Yamamoto, Koji Fujita, Tatsuya Fukumoto, Nagahisa Murakami, Hideo Mure, Yasuhisa Kanematsu, Yasushi Takagi, Yuishin Izumi,

A 65-year-old woman with spinocerebellar ataxia presented with generalized seizures due to subcortical hemorrhaging. Magnetic resonance imaging (MRI) revealed obstruction of the superior sagittal sinus. Despite treatment, she became comatose. MRI newly revealed subdural fluid collection and descent of the brainstem. Her history indicated a recent fall, prompting additional studies, ... Read more >>

Intern. Med. (Internal medicine (Tokyo, Japan))
[2020, :]

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Suspected adverse reaction to compounded preparations prescribed for weight loss: two cases of cerebral venous thrombosis.

Beatrice Mainoli, Mariana Carvalho Dias, Patricia Canhão, Mário Miguel Rosa,

We report two cases of cerebral venous thrombosis associated with the use of compounded preparations containing several active substances prescribed for weight loss. In both cases there is suspicion of additive/synergic interaction with oral contraceptives. The adverse drug reactions were considered serious, being life-threatening and causing hospitalisation for days. ... Read more >>

BMJ Case Rep (BMJ case reports)
[2020, 13(3):]

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Postoperative Unilateral Internal Cerebral Vein Thrombosis with Venous Watershed Infarcts: Case Report and Review of the Literature.

Ai Peng Tan,

BACKGROUND:Cerebral venous complications related to neurosurgical interventions are only rarely reported in the literature. Internal cerebral veins (ICVs) are vulnerable to injury during neurosurgical approaches to the pineal and thalamic regions. The occurrence of unilateral postoperative ICV thrombosis in children is extremely rare, with only 2 such cases reported thus ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 138:158-162]

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Clinical Profile of Cerebral Venous Sinus Thrombosis.

Vithal Narayan Dhadke, Shubhangi V Dhadke, Akshay Kulkarni,

Background and Objectives:Cerebral venous sinus thrombosis (CVT) occurs due to occlusion of the veins and sinuses which drain the brain parenchyma. It is an uncommon form of stroke, predominantly found in young patients1 . Despite advances in the recognition of CVT in recent years, diagnosis and management can be difficult ... Read more >>

J Assoc Physicians India (The Journal of the Association of Physicians of India)
[2020, 68(3):33-35]

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Early Recanalization in Patients With Cerebral Venous Thrombosis Treated With Anticoagulation.

Diana Aguiar de Sousa, Lia Lucas Neto, Antonio Arauz, Ana Luísa Sousa, Denis Gabriel, Manuel Correia, Raquel Gil-Gouveia, Sara Penas, Mariana Carvalho Dias, Manuel A Correia, Marta Carvalho, Patrícia Canhão, José M Ferro,

Background and Purpose- The hypothesis that venous recanalization prevents progression of venous infarction is not established in patients with cerebral venous thrombosis (CVT). Evidence is also scarce on the association between residual symptoms, particularly headache, and the recanalization grade. We aimed to assess, in patients with CVT treated with standard ... Read more >>

Stroke (Stroke)
[2020, 51(4):1174-1181]

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Current imaging modalities for diagnosing cerebral vein thrombosis - A critical review.

Lisette F van Dam, Marianne A A van Walderveen, Lucia J M Kroft, Nyika D Kruyt, Marieke J H Wermer, Matthias J P van Osch, Menno V Huisman, Frederikus A Klok,

Cerebral vein thrombosis (CVT) is a rare presentation of venous thromboembolism. Prompt and accurate diagnosis is essential as delayed recognition and treatment may lead to permanent disability or even death. Since no validated diagnostic algorithms exist, the diagnosis of CVT mainly relies on neuroimaging. Digital subtraction angiography (DSA) is the ... Read more >>

Thromb. Res. (Thrombosis research)
[2020, 189:132-139]

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Cerebral and Splanchnic Vein Thrombosis: Advances, Challenges, and Unanswered Questions.

Nicoletta Riva, Walter Ageno,

Cerebral vein thrombosis (CVT) and splanchnic vein thrombosis (SVT) are two manifestations of venous thromboembolism (VTE) at unusual sites. They have an incidence at least 25-50 times lower than usual site VTE, but represent true clinical challenges. Recent evidence on the epidemiology, risk factors, prognosis, and treatment of CVT and ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(3):]

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Impaired Dynamic Cerebral Autoregulation in Cerebral Venous Thrombosis

Xiping Gong, Jie Chen, Jia Liu, Kehui Dong, Yilong Wang, Xingquan Zhao, Yongjun Wang,

<title>Abstract</title> <p> Background: Cerebral autoregulation is crucial in traumatic brain injury, which might be used for determination the optimal intracranial pressure. Cerebral venous thrombosis is a cerebral vascular disease with the feature of high intracranial pressure, but the autoregulatory mechanism of which remains unknow. We aimed to investigate ... Read more >>

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[Position paper of the Italian Society of Interventional Cardiology (SICI-GISE): Management of patent foramen ovale in patients with cerebral or systemic thromboembolism - 2020].

Giuseppe Tarantini, Gianpiero D'Amico, Claudio Baracchini, Andrea Berni, Sergio Berti, Massimo Chessa, Giovanni Esposito, Achille Gaspardone, Alberto Menozzi, Francesco Meucci, Giuseppe Musumeci, Eustaquio Onorato, Stefano Rigattieri, Francesco Saia, Pino Santoro, Paolo Scacciatella, Daniela Trabattoni, Chiara Fraccaro, Cristian Pristipino,

Patent foramen ovale (PFO) is implicated in the pathogenesis of different clinical syndromes in which it plays variable roles. In 2017 and 2018, four randomized clinical trials were published, allowing for the clarification of certain issues pertaining to cryptogenic stroke. Recently, eight European scientific societies collaborated to the writing of ... Read more >>

G Ital Cardiol (Rome) (Giornale italiano di cardiologia (2006))
[2020, 21(4):50-59]

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Cerebral venous sinus thrombosis following transsphenoidal surgery for craniopharyngioma: A case report.

Tao Chang, Yan-Long Yang, Li Gao, Li-Hong Li,

BACKGROUNDCerebral venous sinus thrombosis (CVST) is a rare condition in patients with craniopharyngioma following transsphenoidal surgery.CASE SUMMARYA 56-year-old man who underwent transsphenoidal surgery for craniopharyngioma 26 d ago presented gradual headache and cerebrospinal fluid leakage while vomiting 5 d post-discharge and required readmission to our department of neurosurgery. After admission, ... Read more >>

World J Clin Cases (World Journal of Clinical Cases)
[2020, 8(6):1158-1163]

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[Paediatric extensiv cerebral venous sinus thrombosis with benign course].

Ahmad Hussam Alsayed,

We report on a 14-year-old girl presenting with an acute headache syndrome that developed after intake of contraceptive drug. Laboratory values showed a homozygous mutation of factor V Leiden and we treated her initially with heparin, then with coumadin. There were no complications during the course of treatment. Interestingly, the ... Read more >>

Fortschr Neurol Psychiatr (Fortschritte der Neurologie-Psychiatrie)
[2020, 88(3):194-197]

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Successful endovascular therapy for cerebral venous sinus thrombosis accompanied by heparin-induced thrombocytopenia.

Yoshihisa Fukushima, Kenji Takahashi, Ichiro Nakahara,

INTRODUCTION:Heparin-induced thrombocytopenia (HIT) is an immune-mediated complication of heparin exposure. A limited number of studies have reported cerebral venous sinus thrombosis accompanied by heparin-induced thrombocytopenia. Here, we present a case of successful endovascular therapy (EVT) without periprocedural heparinization in this situation. CASE PRESENTATION:A 47-year-old woman taking an oral contraceptive was ... Read more >>

Interv Neuroradiol (Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences)
[2020, :1591019919887821]

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Management of antithrombotic therapy in gray areas of venous thromboembolism: a Delphi consensus panel.

Giovanni Barillari, Cristiano Bortoluzzi, Mauro Giorgi, Rossana Orabona, Edoarda Pacetti, Edoardo Sciatti, Marco Zaffaroni, Francesco Dentali,

For some years now, direct-acting oral anticoagulants (DOACs) have entered the clinical practice for stroke prevention in non-valvular atrial fibrillation (NVAF) or for prevention and treatment of venous thromboembolism (VTE). However, there is uncertainty on DOACs' use in some clinical scenarios that are not fully explored by clinical trials, but ... Read more >>

Intern Emerg Med (Internal and emergency medicine)
[2020, :]

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Radiological evaluation in patients with clinical suspicion of cerebral venous sinus thrombosis presenting with nontraumatic headache - a retrospective observational study with a validation cohort.

Håkan Almqvist, Michael Mazya, Alberto Falk Delgado, Anna Falk Delgado,

BACKGROUND:Clinical suspicion of cerebral venous sinus thrombosis (CVST) is imprecise due to non-specific symptoms such as headache. The aim was to retrospectively assess the diagnostic value of nonenhanced CT (neCT) in patients with nontraumatic headache and clinically suspected CVST. METHODS:A retrospective consecutive series of patients referred 2013-2015 for radiology were ... Read more >>

BMC Med Imaging (BMC medical imaging)
[2020, 20(1):24]

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Cerebral venous congestion correlates to acute aneurysm rupture: An illustrative case with Doppler ultrasonography study.

Virginia Annese, Claudia Frau, Noemi Murdeu, Massimo Gregorio, Sandro Sanguigni,

Background:The objective of our description is to shed light on some new hemodynamic and clinical characteristics in the unstable cerebral aneurysm Case: We describe a 54 year old woman who presented a tension headache, that increasing for several days. A CT scan performed in ER suggests a possible arterial ectasia ... Read more >>

eNeurologicalSci (eNeurologicalSci)
[2020, 19:100231]

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Diagnosis and Management of Lemierre's Syndrome Presented with Multifocal Pneumonia and Cerebral Venous Sinus Thrombosis.

Yasar Sattar, Ammu Thampi Susheela, Bibek Karki, Adnan Liaqat, Waqas Ullah, Fnu Zafrullah,

A 27-year-old female patient initially presented with fever, myalgia, sore throat that progressed to multifocal pneumonia, and cerebral sinus venous thrombosis. A combination of upper respiratory symptoms with tooth infection, positive blood culture for Fusobacterium nucleatum, computed tomography (CT) chest finding of multifocal pneumonia, and magnetic resonance imaging (MRI) finding ... Read more >>

Case Rep Infect Dis (Case reports in infectious diseases)
[2020, 2020:6396274]

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Low prevalence of JAK2 V617F mutation in patients with thrombosis and normal blood counts: a retrospective impact study.

Michaël Levraut, Laurence Legros, Charles Drappier, Marie C Béné, Viviane Queyrel, Sophie Raynaud, Nihal Martis,

To determine the prevalence of the V617F Janus Kinase 2 (JAK2) mutation in patients with thrombosis without other biological signs of underlying myeloproliferative neoplasm (MPN) and identify associated risk factors for thrombosis. Over a 10-year period, data were collected from patients with thrombotic events and who had also been screened for the ... Read more >>

J. Thromb. Thrombolysis (Journal of thrombosis and thrombolysis)
[2020, :]

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Timing of Anticoagulation in Patients with Cerebral Venous Thrombosis Requiring Decompressive Surgery: Systematic Review of the Literature and Case Series.

Kristin Salottolo, Russell Bartt, Donald F Frei, Richard J Bellon, Benjamin Atchie, Kathryn McCarthy, David Bar-Or,

OBJECTIVE:Cerebral venous thrombosis (CVT) is a rare type of stroke whose pathophysiology differs from arterial stroke. CVT is treated with systemic anticoagulant therapy even in the setting of intracerebral hemorrhage. Patients who do not respond adequately may require decompressive surgery. The study objective was to examine the timing of anticoagulation ... Read more >>

World Neurosurg (World neurosurgery)
[2020, 137:408-414]

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A novel mutation of SERPINC1 in a patient presenting as recurrent cerebral sinus venous and portal vein thrombosis.

Xin-Yi Teng, Yu Han, Li Yin, Fang-Fang Xu, Zhen-Jie Liu,

: Inherited antithrombin deficiency (OMIM 107300) is a rare autosomal dominant disorder that could increase the risk of venous thromboembolism and is usually caused by mutations of SERPINC1. Herein, we present a case of a novel mutation in the SERPINC1 gene in a Chinese patient. The patient was a 54-year-old ... Read more >>

Blood Coagul. Fibrinolysis (Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis)
[2020, 31(3):229-232]

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Posterior fossa dural arteriovenous fistula.

Adam A Dmytriw, Abdullah Alrashed, Victor X D Yang,

CMAJ (CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne)
[2020, 192(9):E207]

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Cerebral Venous Thrombosis in Hematological Malignancy: Balancing the Risks.

Maria João Pinto, Pedro Bettencourt Medeiros, Fernando Príncipe, Marta Carvalho,

BACKGROUND AND AIM:The coexistence of cerebral venous thrombosis (CVT) and hematological neoplasms is rare. Currently available therapeutic options raise problems concerning the balance of thrombotic and hemorrhagic risks. Our purpose is to characterize a series of cases of CVT and concomitant hematological malignancy, focusing on predisposing factors and treatment strategies. ... Read more >>

J Stroke Cerebrovasc Dis (Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association)
[2020, 29(4):104683]

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Stroke in systemic lupus erythematosus: epidemiology, mechanism, and long-term outcome.

P Guraieb-Chahín, C Cantú-Brito, A Soto-Mota, L Guerrero-Torres, F Flores-Silva, E Chiquete, H Fragoso-Loyo, A González-Duarte, S I Valdés-Ferrer,

OBJECTIVE:To determine stroke prevalence, mechanisms, and long-term outcome in a cohort of Hispanic patients with systemic lupus erythematosus (SLE). METHODS:We analyzed demographical data, the timing between SLE diagnosis and stroke onset, stroke type, recurrence, and outcomes from an institutional database of 4451 patients with SLE followed from 1993 to 2018. ... Read more >>

Lupus (Lupus)
[2020, :961203320908947]

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