Full Text Journal Articles about
Cerebral Palsy

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Walking through life with cerebral palsy: reflections on daily walking by adults with cerebral palsy.

Beate Eltarvåg Gjesdal, Reidun Jahnsen, Prue Morgan, Arve Opheim, Silje Mæland,

Purpose: Walking is a major target in childhood physiotherapy for children with cerebral palsy (CP). Little information exists on the importance or value of walking when these children grow up. The aim of this study was to explore personal reflections on daily walking by adults with CP.Method: Semi-structured individual interviews ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2020, 15(1):1746577]

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An enigmatic case of cortical anopsia: Antemortem diagnosis of a 14-3-3 negative Heidenhain-variant MM1-sCJD.

Julius Obergassel, Lisa Lohmann, Sven G Meuth, Heinz Wiendl, Oliver Grauer, Christopher Nelke,

Sporadic Creutzfeldt-Jakob disease is the predominant type of human prion disease. While routine diagnostic in phenotypic cases has advanced considerably, the clinical heterogeneity and rarity of subtypes continue to constitute a major clinical and diagnostic challenge. Here, we report a peculiar case of the Heidenhain-variant of MM1 sporadic Creutzfeldt-Jakob disease ... Read more >>

Prion (Prion)
[2020, 14(1):24-28]

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Late diagnosis of Lesch-Nyhan disease complicated with end-stage renal disease and tophi burst: a case report.

Cahyani Gita Ambarsari, Daffodilone Cahyadi, Lenny Sari, Oryza Satria, Felly Sahli, Thyrza Laudamy Darmadi, Agustina Kadaristiana,

Background: Lesch-Nyhan disease (LND) is a rare X-linked recessive inborn error of purine metabolism. Late diagnosis of LND may cause significant morbidity. LND cases have never been reported in Indonesia.Case report: A 15-year-old male who had been diagnosed with cerebral palsy was referred to our hospital due to renal failure ... Read more >>

Ren Fail (Renal Failure)
[2020, 42(1):113-121]

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Social isolation and exclusion: the parents' experience of caring for children with rare neurodevelopmental disorders.

Genevieve Currie, Joanna Szabo,

Purpose: The experiences of parents caring for the complex care needs of children with rare neurodevelopmental disorders are not well understood. Parents struggle to meet their children's medical, behavioural, and social needs within and across health, social, and family systems. The purpose of this study was to explore the parents' ... Read more >>

Int J Qual Stud Health Well-being (International journal of qualitative studies on health and well-being)
[2020, 15(1):1725362]

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Resatorvid protects against hypoxic-ischemic brain damage in neonatal rats.

Li-Jun Jiang, Zhen-Xing Xu, Ming-Fu Wu, Gai-Qin Dong, Li-Li Zhang, Jun-Yan Gao, Chen-Xi Feng, Xing Feng,

Secondary brain damage caused by hyperactivation of autophagy and inflammatory responses in neurons plays an important role in hypoxic-ischemic brain damage (HIBD). Although previous studies have implicated Toll-like receptor 4 (TLR4) and nuclear factor kappa-B (NF-κB) in the neuroinflammatory response elicited by brain injury, the role and mechanisms of the ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(7):1316-1325]

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Acupuncture promotes functional recovery after cerebral hemorrhage by upregulating neurotrophic factor expression.

Dan Li, Qiu-Xin Chen, Wei Zou, Xiao-Wei Sun, Xue-Ping Yu, Xiao-Hong Dai, Wei Teng,

Acupuncture is widely used in the treatment of cerebral hemorrhage, and it improves outcomes in experimental animal models and patients. However, the mechanisms underlying the effectiveness of acupuncture treatment for cerebral hemorrhage are still unclear. In this study, a model of intracerebral hemorrhage was produced by injecting 50 μL autologous ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(8):1510-1517]

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Photo-Based Range-of-Motion Measurement: Reliability and Concurrent Validity in Children With Cerebral Palsy.

Mette Johansen, Helle Haslund-Thomsen, Jeanette Kristensen, Søren Thorgaard Skou,

PURPOSE:To investigate intrarater and interrater reliability, agreement, and concurrent validity of a smartphone photography-based application compared with a universal goniometer in children with cerebral palsy. METHODS:Range of motion of hip abduction, popliteal angle, and ankle dorsiflexion was measured with a universal goniometer and a photography-based application in children with cerebral ... Read more >>

Pediatr Phys Ther (Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association)
[2020, 32(2):151-160]

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Psychometric Properties of Clinical Tests of Balance and Vestibular-Related Function in Children With Cerebral Palsy.

Anwar B Almutairi, Jennifer B Christy, Laura Vogtle,

PURPOSE:The purpose of this study was to establish the psychometric properties of clinical tests of balance and vestibular-related function in children with cerebral palsy (CP), aged 7 to 12 years, Gross Motor Function Classification System levels I to III. METHODS:Forty-two children with CP and 33 children with typical development were ... Read more >>

Pediatr Phys Ther (Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association)
[2020, 32(2):144-150]

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Profile of hospital admissions for adults with cerebral palsy: a retrospective cohort study.

Prue Morgan, Joanne Enticott, Rujuta Nikam, Jane Tracy,

AIM:To retrospectively profile acute hospital admissions for a defined cohort of adults with cerebral palsy (CP). METHOD:Five years of health service data were interrogated to identify acute health service use by adults with CP. Admission types were described, admission reasons categorized using International Classification of Diseases, 10th Revision codes, and ... Read more >>

Dev Med Child Neurol (Developmental medicine and child neurology)
[2020, :]

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Development and Content Validity of the Clinical Assessment of Body Alignment for Children With Cerebral Palsy.

Frances K George, Alex Benham, Lynne Gabriel, Judy Purton,

PURPOSE:The purpose of this study is to describe the development and content validity of the clinical assessment of body alignment (CABA) to measure body alignment in children with cerebral palsy. METHODS:Content validity and clinical utility were examined through expert opinion of 283 pediatric physical therapists. Participants reviewed items as matching ... Read more >>

Pediatr Phys Ther (Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association)
[2020, 32(2):137-143]

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Foot and Ankle Musculoskeletal Imaging of Pediatric Patients With Cerebral Palsy.

Jeffrey Otjen, Sarah J Menashe, Ezekiel Maloney, Ramesh S Iyer, Anh-Vu Ngo, Ted C Sousa, Mahesh Thapa,

OBJECTIVE. Any combination of abnormal positioning of the ankle, hindfoot, midfoot, and forefoot is possible in the context of cerebral palsy, but some patterns are more common than others. The purpose of this article is to discuss the radiographic manifestations and surgical management of the following common conditions: equinus, equinoplanovalgus, ... Read more >>

AJR Am J Roentgenol (AJR. American journal of roentgenology)
[2020, :1-9]

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Antenatal magnesium sulphate for the prevention of cerebral palsy in infants born preterm: a double-blind, randomised, placebo-controlled, multi-centre trial.

Hanne Trap Wolf, Jesper Brok, Tine Brink Henriksen, Gorm Greisen, Jannie Dalby Salvig, Ole Pryds, Morten Hedegaard, Tom Weber, Hanne Kristine Hegaard, Anja Pinborg, Lene Drasbek Huusom, ,

OBJECTIVE:To study the effect of antenatal magnesium sulphate (MgSO4 ) on cerebral palsy (CP) in a manner that also provides adequate power for a linked trial sequential analysis. DESIGN:Double-blind, randomised, placebo-controlled, multicentre trial. SETTING:Fourteen Danish obstetric departments. POPULATION:In total, 560 pregnant women at risk for preterm delivery before 32 weeks ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2020, :]

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Challenges Faced by Therapists Providing Services for Infants With or at Risk for Cerebral Palsy.

Afnan S Gmmash, Susan K Effgen, Katie Goldey,

OBJECTIVE:The purpose of this study was to identify the challenges physical therapists (PTs) and occupational therapists (OTs) have in providing early intervention (EI) for infants with or at risk for cerebral palsy. METHODS:Therapists' responses to an open-ended question were collected via survey that was distributed to EI providers and analyzed ... Read more >>

Pediatr Phys Ther (Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association)
[2020, 32(2):88-96]

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Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring.

Bob Z Sun, Dag Moster, Quaker E Harmon, Allen J Wilcox,

Importance:Preeclampsia during pregnancy has been linked to an increased risk of cerebral palsy in offspring. Less is known about the role of preeclampsia in other neurodevelopmental disorders. Objective:To determine the association between preeclampsia and a range of adverse neurodevelopmental outcomes in offspring after excluding preterm births. Design, Setting, and Participants:This ... Read more >>

JAMA Psychiatry (JAMA psychiatry)
[2020, :]

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The general movements assessment in term and late-preterm infants diagnosed with neonatal encephalopathy, as a predictive tool of cerebral palsy by two years of age: a scoping review protocol.

Rudaina Banihani, Judy Seesahai, Maureen Luther, Carmen Rhoden, Paige Church, Elizabeth Asztalos,

<title>Abstract</title> <p> Background Prediction of long-term neurodevelopmental outcomes remains an elusive goal for neonatology. Clinical and socioeconomic markers have not proven to be adequately reliable. The limitation in prognostication includes those term and late-preterm infants born with neonatal encephalopathy. The General Movements Assessment tool by Prechtl has demonstrated ... Read more >>

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High-level motor skills assessment for ambulant children with cerebral palsy: a systematic review and decision tree.

Georgina L Clutterbuck, Megan L Auld, Leanne M Johnston,

AIM:To examine the psychometric evidence for high-level motor skills assessment tools for ambulant, school-aged children with cerebral palsy (CP). METHOD:We searched five databases for population (children with CP aged 5-18y in Gross Motor Function Classification System levels I and II), assessment focus (high-level motor skills), and psychometric evidence. We evaluated ... Read more >>

Dev Med Child Neurol (Developmental medicine and child neurology)
[2020, :]

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Non-trauma fracture increases risk for respiratory disease among adults with cerebral palsy.

Daniel G Whitney,

Individuals with cerebral palsy (CP) manifest skeletal fragility problems early in life and are vulnerable to non-trauma fracture (NTFx), which may exacerbate risk of respiratory disease (RD)- a main cause of premature mortality for this population. The purpose of this study was to determine if adults with CP had greater ... Read more >>

J. Orthop. Res. (Journal of orthopaedic research : official publication of the Orthopaedic Research Society)
[2020, :]

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Cerebral palsy treatment with autologous bone marrow aspirate concentrate challenges for the future

Dusica Maric, Dusan Maric, Mihajlo Radomir, Zoran Milankov, Vladimir Papic, Danilo Vojvodic, Ivan Stanojevic, Ivana Sokolovac, Kristina Milosavljevic, Dzihan Abazovic,

<title>Abstract</title> <p> Background Cerebral Palsy (CP) is a heterogeneous group of conditions that results in permanent motor disability. Recent studies have suggested that cellular transplantation may have functional efficacy in the treatment of CP. We conducted a pilot study of the intrathecal transplantation of autologous bone marrow aspirate ... Read more >>

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Investigation into the reproducibility of the association of cord blood magnesium concentration and cerebral palsy or death in children

Catherine Sherwin, Christopher Dixon, Xiaoxi Liu, Alfred Balch, Maged Costantine,

<title>Abstract</title> <p> Objective: To evaluate the association of cord blood magnesium concentrations at the time of birth with cerebral palsy (CP) and neonatal death. Study Design: A secondary analysis of a randomized controlled trial that randomized women at imminent risk of delivery between 24 and 31 weeks of ... Read more >>

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Does a Reduced Number of Muscle Stem Cells Impair the Addition of Sarcomeres and Recovery from a Skeletal Muscle Contracture? A Transgenic Mouse Model.

Sudarshan Dayanidhi, Matthew C Kinney, Peter B Dykstra, Richard L Lieber,

BACKGROUND:Children with cerebral palsy have impaired muscle growth and muscular contractures that limit their ROM. Contractures have a decreased number of serial sarcomeres and overstretched lengths, suggesting an association with a reduced ability to add the serial sarcomeres required for normal postnatal growth. Contractures also show a markedly reduced number ... Read more >>

Clin. Orthop. Relat. Res. (Clinical orthopaedics and related research)
[2020, 478(4):886-899]

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Magnesium sulphate for foetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis.

Hanne Trap Wolf, Lene Drasbek Huusom, Tine Brink Henriksen, Hanne Kristine Hegaard, Jesper Brok, Anja Pinborg,

BACKGROUND:Ordinary meta-analyses indicate that magnesium sulphate (MgSO4 ) treatment to women at imminent risk for preterm delivery decreases the offspring's risk of cerebral palsy (CP). However, repetitive testing of cumulative data calls for statistical caution, e.g., by trial sequential analysis (TSA), for which there were previously insufficient samples to draw ... Read more >>

BJOG (BJOG : an international journal of obstetrics and gynaecology)
[2020, :]

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Commentary on "Development and Validity of the Clinical Assessment of Body Alignment for Children With Cerebral Palsy".

Victor Santamaria, Jaya Rachwani,

Pediatr Phys Ther (Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association)
[2020, 32(2):143]

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Commentary on "Challenges Faced by Therapists Providing Services for Infants With or at Risk for Cerebral Palsy".

Philippa H Campbell,

Pediatr Phys Ther (Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association)
[2020, 32(2):97]

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Cortical ischaemic patterns in term partial-prolonged hypoxic-ischaemic injury-the inter-arterial watershed demonstrated through atrophy, ulegyria and signal change on delayed MRI scans in children with cerebral palsy.

Anith Chacko, Savvas Andronikou, Ali Mian, Fabrício Guimarães Gonçalves, Schadie Vedajallam, Ngoc Jade Thai,

The inter-arterial watershed zone in neonates is a geographic area without discernible anatomic boundaries and difficult to demarcate and usually not featured in atlases. Schematics currently used to depict the areas are not based on any prior anatomic mapping, compared to adults.Magnetic resonance imaging (MRI) of neonates in the acute ... Read more >>

Insights Imaging (Insights into imaging)
[2020, 11(1):53]

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Brain Stiffness Relates to Dynamic Balance Reactions in Children With Cerebral Palsy.

Grace McIlvain, James B Tracy, Charlotte A Chaze, Drew A Petersen, Gabrielle M Villermaux, Henry G Wright, Freeman Miller, Jeremy R Crenshaw, Curtis L Johnson,

Cerebral palsy is a neurodevelopmental movement disorder that affects coordination and balance. Therapeutic treatments for balance deficiencies in this population primarily focus on the musculoskeletal system, whereas the neural basis of balance impairment is often overlooked. Magnetic resonance elastography (MRE) is an emerging technique that has the ability to sensitively ... Read more >>

J. Child Neurol. (Journal of child neurology)
[2020, :883073820909274]

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