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Central Vertigo

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An enigmatic case of cortical anopsia: Antemortem diagnosis of a 14-3-3 negative Heidenhain-variant MM1-sCJD.

Julius Obergassel, Lisa Lohmann, Sven G Meuth, Heinz Wiendl, Oliver Grauer, Christopher Nelke,

Sporadic Creutzfeldt-Jakob disease is the predominant type of human prion disease. While routine diagnostic in phenotypic cases has advanced considerably, the clinical heterogeneity and rarity of subtypes continue to constitute a major clinical and diagnostic challenge. Here, we report a peculiar case of the Heidenhain-variant of MM1 sporadic Creutzfeldt-Jakob disease ... Read more >>

Prion (Prion)
[2020, 14(1):24-28]

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Intratympanic gentamycine for Ménière's disease: is there a selective vestibulotoxic effect?

András Molnár, Stefani Maihoub, Anita Gáborján, László Tamás, Ágnes Szirmai,

PURPOSE:The aim of our study is to investigate the effectiveness and safety of the treatment, based on vertigo diaries and pure tone audiograms. METHODS:The complete medical documentation of 105 definite patients suffering from Ménière's disease was analyzed. In the studied group, nine patients were treated with intratympanic gentamycine. Long-term follow-up ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2020, :]

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Physical therapy interventions for older people with vertigo, dizziness and balance disorders addressing mobility and participation: a systematic review

Verena Regauer, Eva Seckler, Martin Müller, Petra Bauer,

<title>Abstract</title> <p> Background Vertigo, dizziness and balance disorders (VDB) are among the most relevant contributors to the burden of disability among older adults living in the community and associated with immobility, limitations of activities of daily living and decreased participation. The aim of this study was to identify ... Read more >>

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Changes in Cortical Activation During Dual-Task Walking in Individuals With and Without Visual Vertigo.

Carrie W Hoppes, Theodore J Huppert, Susan L Whitney, Pamela M Dunlap, Nikki L DiSalvio, Kefah M Alshebber, Joseph M Furman, Yong H Kwon, Andrea L Rosso,

BACKGROUND AND PURPOSE:Persons with vestibular disorders are known to have slower gait speed with greater imbalance and veering during dual-task walking than healthy individuals, but the cerebral mechanisms are unknown. The purpose of this study was to determine whether individuals with visual vertigo (VV) have different cerebral activation during dual-task ... Read more >>

J Neurol Phys Ther (Journal of neurologic physical therapy : JNPT)
[2020, 44(2):156-163]

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Magnetic resonance imaging of Ménière's disease: early clinical experience in a UK centre.

I Pai, S Mendis, L Murdin, P Touska, S Connor,

BACKGROUND:Recent developments in magnetic resonance imaging have enabled demonstration of endolymphatic hydrops, and the clinical application of these imaging studies in Ménière's disease is being explored. OBJECTIVE:To evaluate our centre's experience to date of hydrops magnetic resonance imaging in patients with episodic vertigo. METHODS:Magnetic resonance imaging was performed using a ... Read more >>

J Laryngol Otol (The Journal of laryngology and otology)
[2020, :1-9]

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A Young Woman Presenting with Encephalopathy: A Case Report.

Mario Kofler, Stefan Kiechl, Raimund Helbok,

Neurocrit Care (Neurocritical care)
[2020, 32(2):630-632]

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[Dizziness and vertigo in a tertiary ENT emergency department].

L Comolli, M Goeldlin, J Gaschen, C Kammer, T C Sauter, M D Caversaccio, R Kalla, U Fischer, G Mantokoudis,

BACKGROUND:Although vestibular symptoms are amongst the most frequent reasons for seeking emergency medical help, many patients remain undiagnosed. OBJECTIVE:In this cross-sectional study, we investigated the spectrum of vertigo and dizziness in a tertiary ear, nose, and throat (ENT) emergency department (ED). Furthermore, we investigated the attendant symptoms, clinical signs, and the ... Read more >>

HNO (HNO)
[2020, :]

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On-Demand and Low Dose Intratympanic Gentamicin for Meniere's Disease: A Customized Approach.

Erika Celis-Aguilar, Karla Mariana Castro-Bórquez, Alejandra Obeso-Pereda, Lucero Escobar-Aispuro, Alan Burgos-Paez, José M Alarid-Coronel, Sergio Verdiales-Lugo, Ivonne Carolina León-Leyva, Cosme Francisco Trejo-González, Lilia Miriam López-Favela, Leticia Martínez-Román,

OBJECTIVE:To evaluate the efficacy of on demand and low dose intratympanic gentamicin (ITG) in patients with intractable Meniere's disease (MD). STUDY DESIGN:Clinical chart review. SETTING:Secondary care center. PATIENTS:Subjects with MD who failed conventional treatment and underwent on demand ITG infiltration from June 2013 to December 2018. INTERVENTION:0.4 to 0.5 ml of ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2020, 41(4):504-510]

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Posterior Semicircular Canal Dehiscence: Case Series and Systematic Review.

Joshua A Lee, Yuan F Liu, Shaun A Nguyen, Theodore R McRackan, Ted A Meyer, Habib G Rizk,

OBJECTIVE:To conduct a systematic review of posterior semicircular canal dehiscence (PSCD) and to present a series of patients with PSCD with and without classic third-window symptoms. DATA SOURCES:PubMed, Scopus, and the Cochrane Library from inception until April 2019. Case series of five patients seen in a multidisciplinary, vestibular-focused, neurotology clinic. ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2020, 41(4):511-521]

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Translation and cross-cultural adaptation of the Visual Vertigo Analogue Scale for use in Argentina.

Daniel Héctor Verdecchia, Daniel Hernandez, Mauro Federico Andreu, Sandra Salzberg,

BACKGROUND AND OBJECTIVE:Visual dizziness occurs when high visual dependence interferes with compensation for a vestibular lesion and leads to intolerance in situations of visual conflict. The Visual Vertigo Analogue Scale (VVAS) is a self-administered, valid and reliable questionnaire that serves to assess visual dizziness. The use of questionnaires in different ... Read more >>

Acta Otorrinolaringol Esp (Acta otorrinolaringologica espanola)
[2020, :]

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Retraction Note to: Menière's disease: combined pharmacotherapy with betahistine and the MAO-B inhibitor selegiline-an observational study.

Michael Strupp, Ludwig Kraus, Franz Schautzer, Dan Rujescu,

The authors have retracted this article. ... Read more >>

J. Neurol. (Journal of neurology)
[2020, 267(4):1225]

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Physical therapy interventions for cervicogenic dizziness in a military-aged population: protocol for a systematic review.

Carrie W. Hoppes, Anthony J. Romanello, Kathryn E. Gaudette, William K. Herron, Anne E. McCarthy, Catherine J. McHale, Joan Bares, Rose Turner, Susan L. Whitney,

BackgroundTraumatic cervicogenic dizziness is dizziness that is temporally associated with neck pain and injury after other causes of dizziness have been excluded. It can lead to activity limitations and participation restrictions that may include lost duty or work days. The objective of this systematic review is to determine which interventions ... Read more >>

Syst Rev (Systematic reviews)
[2020, 9:]

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Underwater Endoscopic Repair of Superior Canal Dehiscence.

Francis Creighton, Samuel R Barber, Bryan K Ward, Jeffrey D Sharon, John P Carey,

: Superior canal dehiscence (SCD) is a bony defect of the superior semicircular canal (SCC). Patients with SCD Syndrome (SCDS) may experience symptoms such as aural fullness, pulsatile tinnitus, hyperacusis, autophony, or pressure or noise-induced vertigo . The defect can be repaired in various ways, but there is potential for ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2020, 41(4):560]

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Double-blind randomized controlled trial on efficacy of cupulolith repositioning maneuver for treatment of apogeotropic horizontal canal benign paroxysmal positional vertigo.

Tae Hoon Kong, Mee Hyun Song, Jin Wook Kang, Dae Bo Shim,

Backgrounds: Although various therapeutic maneuvers have been proposed, it is still unclear which maneuver is better to treat apogeotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV).Objectives: This study aimed to assess the therapeutic efficacy of the cupulolith repositioning maneuver (CuRM) in apogeotropic HC-BPPV in comparison with the therapeutic head-shaking maneuver ... Read more >>

Acta Otolaryngol. (Acta oto-laryngologica)
[2020, :1-6]

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The semicircular canal function tests contribute to identifying unilateral idiopathic sudden sensorineural hearing loss with vertigo.

Ruirui Guan, Zhu Zhao, Xiaotao Guo, Jingwu Sun,

BACKGROUND:Few studies focused on the prognosis of unilateral idiopathic sudden sensorineural hearing loss (UISSNHL) with vertigo. OBJECTIVES:To describe how the semicircular canal (SCC) function tests may prove helpful in the diagnosis of UISSNHL with vertigo. MATERIAL AND METHODS:59 UISSNHL patients underwent audiometry, caloric test and video head impulse test (vHIT). ... Read more >>

Am J Otolaryngol (American journal of otolaryngology)
[2020, :102461]

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Clinical, ocular motor, and imaging profile of Niemann-Pick type C heterozygosity.

Tatiana Bremova-Ertl, Clara Sztatecsny, Matthias Brendel, Marlene Moser, Bettina Möller, Dirk A Clevert, Stefanie Beck-Wödl, Celia Kun-Rodrigues, Jose Bras, Axel Rominger, Dimitar Ninov, Michael Strupp, Susanne A Schneider,

OBJECTIVE:To characterize subclinical abnormalities in asymptomatic heterozygote NPC1 mutation carriers as markers of neurodegeneration. METHODS:Motor function, cognition, mood, sleep, and smell function were assessed in 20 first-degree heterozygous relatives of patients with Niemann-Pick disease type C (NPC) (13 male, age 52.7 ± 9.9 years). Video-oculography and abdominal ultrasound with volumetry ... Read more >>

Neurology (Neurology)
[2020, :]

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Anaesthetic managment and clinical outcomes of parturients with COVID-19: a multicentre, retrospective, propensity score matched cohort study

Yuan Zhang, Rong Chen, Jie Wang, Yuan Gong, Qin Zhou, Hui-hui Cheng, Zhong-yuan Xia, Xiangdong Chen, Qing-tao Meng, Daqing Ma,

Objective:To analyse the clinical features of COVID−19 parturients, and to compare anaesthetic regimen and clinical outcomes in parturients with or without COVID−19 undergoing cesarean delivery.Methods: Data were extracted from the electronic medical record of 3 medical institutions in Hubei Province, China, from June 1, 2019 to March 20, 2020 according ... Read more >>

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Can emergency physicians accurately rule out a central cause of vertigo using the HINTS exam? A systematic review and meta-analysis.

Robert Ohle, Renee-Anne Montpellier, Virginie Marchadier, Aidan Wharton, Sarah McIsaac, Mackenzie Anderson, David Savage,

INTRODUCTION:Dizziness is a common complaint presented in the emergency department. A subset of these patients will present with acute vestibular syndrome (AVS). AVS is a clinical syndrome defined by the presence of vertigo, nystagmus, head motion intolerance, ataxia, and nausea/vomiting. These symptoms are most often due to benign vestibular neuritis; ... Read more >>

Acad Emerg Med (Academic emergency medicine : official journal of the Society for Academic Emergency Medicine)
[2020, :]

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How rare is benign paroxysmal positional vertigo in children? A review of 20 cases and their epidemiology.

Hyo Geun Choi, Gibbeum Kim, Byeong Joon Kim, Sung Kwang Hong, Hyung-Jong Kim, Hyo-Jeong Lee,

OBJECTIVE:The clinical features and incidence of benign paroxysmal positional vertigo (BPPV) are not well known in pediatric populations. The aim of this study was to describe the clinical characteristics of pediatric BPPV and to estimate the frequency of pediatric BPPV in the general population. METHODS:We retrospectively reviewed the medical records ... Read more >>

Int. J. Pediatr. Otorhinolaryngol. (International journal of pediatric otorhinolaryngology)
[2020, 132:110008]

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Author's reply to the Letter to the Editor "Therapeutic strategies in the treatment of Menière's disease: the Italian experience".

N Quaranta, P Picciotti,

There is still controversy on the role of hyperinsulinemia and endogenous antisecretory factor (EAF) in Meniere's disease. In the literature, there is no mention on glucose uptake or specially processed cereals (SPC). Nevertheless, the role of EAF and its inhibition by SPC should be taken into account in future research. ... Read more >>

Eur Arch Otorhinolaryngol (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery)
[2020, :]

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Microvascular decompression: is routine postoperative CT imaging necessary?

Gökce Hatipoglu Majernik, Shadi Al-Afif, Hans E Heissler, Luisa Cassini Ascencao, Joachim K Krauss,

BACKGROUND:Postoperative head CT imaging is routinely performed for detection of postoperative complications following intracranial procedures. However, it remains unclear whether with regard to radiation exposure, costs, and possibly lack of consequences this practice is truly justified in various operative procedures. The objective of this study was to analyze whether routine ... Read more >>

Acta Neurochir (Wien) (Acta neurochirurgica)
[2020, :]

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[Current aspects of vertigo and dizziness in advanced age].

L E Walther, A Blödow,

Vertigo and dizziness in advanced age are common complaints in daily clinical practice. The otorhinolaryngologist holds a central position in the differential diagnostic clarification. Age-related disorders (e.g. benign positional vertigo, presbyvestibulopathy, otholith functional disorders) arise due to a physiological, individually distinct and objectively detectable reduction in the sensitivity of sensory ... Read more >>

HNO (HNO)
[2020, 68(3):191-198]

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Human Temporal Bone Study of Vestibular Histopathology in Cochlear Implant Patients With Cochlear Hydrops.

Brooke M Su-Velez, Ivan A Lopez, Akira Ishiyama, Gail Ishiyama,

HYPOTHESIS:Endolymphatic hydrops (EH) associated with cochlear implantation are associated with vestibular dysfunction. BACKGROUND:Vestibular dysfunction is a known risk after cochlear implantation (CI). CI has been shown to cause cochlear hydrops due to fibrosis surrounding the ductus reuniens. However, the association of cochlear hydrops with vestibular hydrops and the relationship to ... Read more >>

Otol. Neurotol. (Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology)
[2020, :]

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Serotonin-norepinephrine reuptake inhibitors for the prevention of migraine and vestibular migraine: a systematic review and meta-analysis.

Fengzhi Wang, Jiaoqi Wang, Yumeng Cao, Zhongxin Xu,

BACKGROUND AND OBJECTIVES:The role of serotonin-norepinephrine reuptake inhibitors (SNRIs) in migraine prophylaxis has not been completely established. Current treatments for vestibular migraine (VM) are based on scarce evidence. We aimed to perform an updated review focusing on the efficacy and tolerability of SNRIs for migraine and VM prevention. METHODS:We searched ... Read more >>

Reg Anesth Pain Med (Regional anesthesia and pain medicine)
[2020, :]

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Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments.

Neeraj Tandon, Satyapal Singh Yadav,

ETHNOPHARMACOLOGICAL RELEVANCE:Withania somnifera popularly known as Aswagandha or Indian Ginseng/Poison Gooseberry have thousands years of history of use in Indian traditional medicine. Besides, finding place root of the plant as Indian Ginseng, Ayurveda also uses root of this plant as general health tonic, adaptogenic, nootropic, immunomodulatory etc. With its widespread ... Read more >>

J Ethnopharmacol (Journal of ethnopharmacology)
[2020, 255:112768]

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