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Cavernous Sinus Syndromes

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Fusobacterium necrophorum Septicemia Leading to Lemierre’s Syndrome in an Immunocompetent Individual: A Case Report.

Balarama K Surapaneni, Hanad Omar, Michele M Iguina, Manuel Suarez,

Lemierre syndrome is a life-threatening condition associated with infection by obligate anaerobes residing in oropharyngeal mucosa. The most common organism responsible is Fusobacterium necrophorum. We report a case in a 69-year-old gentleman. The man with past medical history of hypertension, anxiety and chronic alcohol abuse was brought in by his family for ... Read more >>

Cureus (Cureus)
[2020, 12(3):]

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Long-term follow-up for ectopic ACTH-secreting pituitary adenoma in a single tertiary medical center and a literature review.

Jianyu Zhu, Lin Lu, Yong Yao, Shi Chen, Wei Li, Hui You, Feng Feng, Ming Feng, Yi Zhang, Zhicheng Wang, Xu Sun, Xiaoxu Li, Huijuan Zhu, Renzhi Wang, Zhaolin Lu,

BACKGROUND:Ectopic ACTH-secreting pituitary adenoma (EAPA) are a rare cause of Cushing's disease. Due to the lack of consensus and experience in terms of the diagnosis and treatment of EAPAs, preoperative identification and optimal treatment remain challenging. PURPOSE:To investigate the characteristics of EAPAs and offer some proposals for the diagnosis and ... Read more >>

Pituitary (Pituitary)
[2020, 23(2):149-159]

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Gradenigo's Syndrome with Carotid Septic Stenosis.

Ana Sousa Menezes, Daniela Ribeiro, Filipa Balona, Ricardo Maré, Cátia Azevedo, Jaime Rocha, Luís Dias,

Gradenigo's syndrome was firstly described in 1907 by Giusseppe Gradenigo and is defined as the clinical triad of suppurative otitis media, ipsilateral abducens nerve palsy, and pain in the distribution of the first and the second branches of the trigeminal nerve. Since the advent of antibiotics, the incidence of this ... Read more >>

Case Rep Otolaryngol (Case reports in otolaryngology)
[2020, 2020:9439184]

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Tolosa-Hunt Syndrome: Long-Term Outcome and Role of Steroid-Sparing Agents.

Anupriya Arthur, Ajith Sivadasan, Pavitra Mannam, A T Prabakhar, Sanjith Aaron, Vivek Mathew, M Karthik, Rohith Ninan Benjamin, Shaikh Atif Iqbalahmed, Gideon Lyngsyun Rynjah, Mathew Alexander,

Background:Tolosa-Hunt Syndrome (THS) is one of the causes of cavernous sinus syndrome causing painful ophthalmoplegia. Literature on long-term outcome of this rare condition is scarce. Aims and Objectives:The aim is to study the recurrence and role of steroid-sparing agents in THS. Methodology:All cases of THS treated at a tertiary-level teaching ... Read more >>

Ann Indian Acad Neurol (Annals of Indian Academy of Neurology)
[2020, 23(2):201-205]

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Granulomatous hypophysitis causing compression of the internal carotid arteries reversible with azathioprine and rituximab treatment.

Pauline Gendreitzig, Jürgen Honegger, Marcus Quinkler,

INTRODUCTION:Compression of the internal carotid artery (ICA) in the cavernous sinus area is a rare event and is mostly associated with pituitary adenomas and meningiomas. Other causes of ICA compression are less well known. We present a rare case of granulomatous hypophysitis causing compression of the ICA, which was treated ... Read more >>

Pituitary (Pituitary)
[2020, 23(2):103-112]

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Unusual Cause of Hypopituitarism: Sphenoid Mucocele.

Elif Gozgec, Hayri Ogul,

Paranasal sinus mucocele is cystic, expansile, benign masses that contain mucus surrounded by epithelium. It causes significant locally destruction of the sinus wall and present with various symptoms depending on the pressure on neighboring structures. Sphenoid sinus mucocele constitutes 1% to 2% of all paranasal sinus mucoceles. Headache is the ... Read more >>

J Craniofac Surg (The Journal of craniofacial surgery)
[2020, :]

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Eikenella Corrodens and Streptococcus anginosus co-infection causing skull base osteomyelitis and internal carotid artery lesion.

Kishan Patel, Connie Park, Zain Memon, Nazish Ilyas,

A 35-year-old male presented with headaches and fevers. MRI of his head showed skull-based infection of the clivus extended to the right internal carotid artery. Blood and sinus cultures were positive for Eikenella corrodens and Streptococcus anginosus. He had intravenous antibiotics and sinus washout. The patient had full neurological recovery ... Read more >>

IDCases (IDCases)
[2020, 20:e00740]

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Low-grade Leiomyosarcoma of the Cavernous Sinus in an HIV Positive Patient: Case Report.

Laura Morales R, Angelina Álvarez, Maria Paulina Noreña, Felipe Torres, José Esguerra,

Primary leiomyosarcomas of the central nervous system are extremely rare tumors, with few cases reported in the literature. In this article we report the case of a patient with an intracranial leiomyosarcoma of the cavernous sinus. This is the case of a 23-year-old man with a history of human immunodeficiency virus ... Read more >>

Cureus (Cureus)
[2020, 12(1):e6758]

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Thyroid carcinoma with atypical metastasis to the pituitary gland and unexpected postmortal diagnosis.

Anna Popławska-Kita, Marta Wielogórska, Łukasz Poplawski, Katarzyna Siewko, Agnieszka Adamska, Piotr Szumowski, Piotr Myśliwiec, Janusz Myśliwiec, Joanna Reszeć, Grzegorz Kamiński, Janusz Dzięcioł, Dorota Tobiaszewska, Małgorzata Szelachowska, Adam Jacek Krętowski,

Summary:Papillary thyroid gland carcinoma is the most common type of malignancy of the endocrine system. Metastases to the pituitary gland have been described as a complication of papillary thyroid cancer in few reported cases since 1965. We report the case of a 68-year-old female patient with a well-differentiated form of ... Read more >>

Endocrinol Diabetes Metab Case Rep (Endocrinology, diabetes & metabolism case reports)
[2020, 2020:]

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Cranio-Orbital and Orbitocranial Approaches to Orbital and Intracranial Disease: Eye-Opening Approaches for Neurosurgeons.

Hussam Abou-Al-Shaar, Khaled M Krisht, Michael A Cohen, Abdullah M Abunimer, Jayson A Neil, Michael Karsy, Gmaan Alzhrani, William T Couldwell,

Orbital approaches for targeting intracranial, orbital, and infratemporal disease have evolved over the years in an effort to discover safe, reliable, effective, and cosmetically satisfying surgical corridors. The surgical goals of these approaches balance important factors such as proximity of the lesion to the optic nerve, the degree of anticipated ... Read more >>

Front Surg (Frontiers in surgery)
[2020, 7:1]

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Cavernous sinus thrombosis caused by Streptococcus constellatus-associated Lemierre syndrome presenting as an isolated abducens nerve palsy.

Landon J Rohowetz, Sean M Gratton, Daniel Dansdill, Cory J Miller, Sarah Dubin,

Purpose:To describe a patient with Streptococcus constellatus-associated Lemierre syndrome complicated by eventual cavernous sinus thrombosis (CST) that manifested as an isolated abducens nerve palsy. Observations:A patient with a history of heavy alcohol use presented with Lemierre syndrome caused by an odontogenic infection due to Streptococcus constellatus. Despite initiation of intravenous ... Read more >>

Am J Ophthalmol Case Rep (American journal of ophthalmology case reports)
[2020, 18:100592]

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External jugular venous sampling for Cushing's disease in a patient with hypoplastic inferior petrosal sinuses.

Keyan A Peterson, Christofer D Burnette, Kyle M Fargen, Patrick A Brown, James L West, Stephen B Tatter, Stacey Q Wolfe,

The authors report the case of a 30-year-old female patient with suspected Cushing's disease with an anatomical variation of hypoplastic inferior petrosal sinuses and nearly exclusive anterior drainage from the cavernous sinus, who underwent external jugular venous blood sampling with successful disease confirmation and microadenoma localization. The patient presented with ... Read more >>

J. Neurosurg. (Journal of neurosurgery)
[2020, :1-4]

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Management of Orbital Masses: Outcomes of Endoscopic and Combined Approaches With No Orbital Reconstruction.

Ryan A Rimmer, Alexander E Graf, Judd H Fastenberg, Jurij Bilyk, Gurston G Nyquist, Marc R Rosen, Michael P Rabinowitz, Mindy R Rabinowitz,

Introduction:The endoscopic endonasal approach to management of orbital pathology has expanded. Due to the rarity of these conditions, most reports in the literature consist of small case reports. We report a series from a single institution with a focus on outcomes. Methods:A retrospective chart review was carried out between 2010 ... Read more >>

Allergy Rhinol (Providence) (Allergy & rhinology (Providence, R.I.))
[2020, 11:2152656719899922]

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Surgical Management of Bilateral Venous Malformation (Cavernous Hemangiomas) of the Maxillary Sinus.

Takashi Anzai, Shin Ito, Atsushi Yamashita, Takuma Ide, Shori Tajima, Hiroko Okada, Fumihiko Matsumoto, Katsuhisa Ikeda,

According to International Society for the Study of Vascular Anomalies classification 2018, "hemangioma" should be classified as either vascular tumor or vascular malformation (VM). So-called "cavernous hemangioma" is categorized as VM. VM rarely involves the mucous membranes of the sinonasal cavity and typically arises unilaterally from the sinonasal cavity. Bilateral ... Read more >>

Case Rep Otolaryngol (Case reports in otolaryngology)
[2020, 2020:8606103]

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Clinicopathological Features and Microsurgical Management of Lesions Located in the Cavernous Sinus: Analysis of 66 Cases.

Mengzhao Feng, Dingkang Xu, Guoqing Wang, Fang Wang, Fuyou Guo,

AIM:To investigate the clinicopathological features and related factors affecting microsurgical resection of lesions in the cavernous sinus. MATERIAL AND METHODS:Clinical data of 66 patients undergoing microsurgery for lesions located in the cavernous sinus from January 2011 to December 2017 were retrospectively reviewed. RESULTS:Histopathological examination revealed benign lesions in 60 (90.9%) ... Read more >>

Turk Neurosurg (Turkish neurosurgery)
[2020, 30(2):171-177]

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Dural arteriovenous fistulas and headache features: an observational study.

Ilenia Corbelli, Francesca De Maria, Paolo Eusebi, Michele Romoli, Gabriela Cardaioli, Mohammed Hamam, Piero Floridi, Letizia Maria Cupini, Paola Sarchielli, Paolo Calabresi,

BACKGROUND:Dural arteriovenous fistulas are intracranial vascular malformations, fed by dural arteries and draining venous sinuses or meningeal veins. Clinical course varies widely and ranges from benign with spontaneous remission to fatal, due to cerebral hemorrhage. In a 10-year single institution experience, clinical presentation of dural arteriovenous fistulas, and in particular ... Read more >>

J Headache Pain (The journal of headache and pain)
[2020, 21(1):6]

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Parasellar meningioma presenting by stroke and bilateral occlusion of the internal carotid arteries: A case report.

Sherifa A Hamed,

Cerebrovascular stroke caused by skull base meningioma has been rarely reported. A 30-year-old male presented (April 2015) with acute right-sided hemiplegia. His brain neuroimaging (computerized tomography and magnetic resonance imaging) showed left ischemic infarction in the territory of middle cerebral artery. Magnetic resonance imaging also showed a right parasellar solid ... Read more >>

SAGE Open Med Case Rep (SAGE Open Medical Case Reports)
[2020, 8:2050313X20902337]

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[Cavernous sinus syndrome secondary to thrombophlebitis due to Streptococcus intermedius complicated with vasculitis of the internal carotid artery and brain abscesses].

D A Anguizola-Tamayo, A Ballvé-Martín, D Campos-Fernández, M Morais-Dias, M Deck, A García-Tornel, M Muchada, C Vert, M Rubiera,

INTRODUCTION:Thrombophlebitis of the cavernous sinus is a severe infectious disease with high mortality and morbidity. It is usually diagnosed at a late stage and requires a number of visits to the emergency department in most cases, and the prognosis is highly dependent on prompt treatment. Despite its severity, evidence regarding ... Read more >>

Rev Neurol (Revista de neurologia)
[2020, 70(1):19-22]

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Tumour-infiltrating cytotoxic T lymphocytes in somatotroph pituitary neuroendocrine tumours.

Donato Iacovazzo, Sabrina Chiloiro, Eivind Carlsen, Antonio Bianchi, Antonella Giampietro, Tommaso Tartaglione, Chiara Bima, Maria Elena Bracaccia, Francesca Lugli, Liverana Lauretti, Carmelo Anile, Marco Gessi, Cesare Colosimo, Guido Rindi, Alfredo Pontecorvi, Márta Korbonits, Laura De Marinis,

INTRODUCTION:Somatotroph pituitary tumours are often resistant to first-generation somatostatin analogues and can invade the surrounding structures, limiting the chances of curative surgery. Recent studies suggested that the immune microenvironment and pro-angiogenic factors can influence neuroendocrine tumour prognosis. In this study, we aimed to investigate the prognostic role of immune cell-specific ... Read more >>

Endocrine (Endocrine)
[2020, 67(3):651-658]

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An Unusual Retinal Vessel Modification in Patients Affected by JIA-Uveitis with a Follow-Up Longer Than 16 Years.

Alessandro Abbouda, Irene Abicca, Simone Bruschi, Federico Ricci, Gianluca Aloe, Maria Pia Paroli,

Purpose:To report unusual and rare clinical changes of retinal vessel pattern in a series of patients affected by Juvenile Idiopathic Arthritis (JIA) uveitis with a follow-up longer than 16 years. Methods:A series of three patients with JIA-uveitis followed at the University of Rome "Sapienza" from 1998 to 2014 were reported. ... Read more >>

Case Rep Ophthalmol Med (Case reports in ophthalmological medicine)
[2020, 2020:4720819]

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Orbital Apex Syndrome: A Review.

Akshay Badakere, Preeti Patil-Chhablani,

Orbital apex syndrome is characterized by vision loss from optic neuropathy and ophthalmoplegia due to the involvement of ocular motor nerves in the anatomical region of the orbital apex. Patients could present with signs and symptoms deriving from the involvement of structures within the orbital apex, the superior orbital fissure ... Read more >>

Eye Brain (Eye and brain)
[2019, 11:63-72]

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The importance of landmarks in endoscopic endonasal reinterventions: the transpterygoid transcavernous approach.

Rafael Martinez-Perez, Giuliano Silveira-Bertazzo, Ricardo L Carrau, Daniel M Prevedello,

BACKGROUND:Sellar and parasellar regions are anatomically complex region and in close relationship with important neurovascular structures. Hence, surgical treatment of recurrent aggressive pituitary adenomas invading the cavernous sinus represents an operative challenge, given the lack of landmarks that are missed because of the scar tissue and previous interventions. METHODS:We describe ... Read more >>

Acta Neurochir (Wien) (Acta neurochirurgica)
[2020, 162(4):875-880]

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A Case of Idiopathic Orbital Inflammation with Shallow Anterior Chamber and Choroidal Detachment.

Yohei Sato, Natsuko Mano, Hiroko Watanabe, Makiko Miyamoto, Kazuhiro Shimizu, Noriko Mukai, Masashi Mimura, Hidehiro Oku, Tsunehiko Ikeda,

We report a case of idiopathic orbital inflammation with a shallow anterior chamber and choroidal detachments. This study involved an 87-year-old female patient who presented at our department after becoming aware of the progression of diplopia. Examination of the patient's right eye revealed proptosis, as well as conjunctival edema with ... Read more >>

Case Rep Ophthalmol (Case Reports in Ophthalmology)
[2020, 11(1):8-15]

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Results and predictors of outcome of endoscopic endonasal surgery in Cushing's disease: 20-year experience of an Italian referral Pituitary Center.

F Guaraldi, M Zoli, S Asioli, G Corona, D Gori, F Friso, E Pasquini, A Bacci, A Sforza, D Mazzatenta,

PURPOSE:To assess outcomes and predictors of early and long-term remission in patients with Cushing's disease (CD) due to ACTH-secreting adenomas treated via endoscopic endonasal approach (EEA). METHODS:This is a retrospective study. Consecutive patients operated for CD from 1998 to 2017 in an Italian referral Pituitary Center were enrolled. Clinical, radiological, ... Read more >>

J. Endocrinol. Invest. (Journal of endocrinological investigation)
[2020, :]

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Pituitary carcinoma: Two case reports and review of literature.

Lai Xu, Karam Khaddour, Jie Chen, Keith M Rich, Richard J Perrin, Jian Li Campian,

BACKGROUND:Pituitary carcinoma is a rare type of malignancy that can be very difficult to diagnose and treat. Many cases were diagnosed at autopsy. Delays in diagnosis often adversely impact patients' outcomes. Even with prompt diagnosis, treatment decisions remain challenging in the absence of randomized controlled trials. CASE SUMMARY:We report two ... Read more >>

World J Clin Oncol (World journal of clinical oncology)
[2020, 11(2):91-102]

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