Full Text Journal Articles about
Cannabinoid Poisoning

Advertisement

Find full text journal articles






Cannabis and synthetic cannabinoid exposure reported to the Israel poison information center: Examining differences in exposures to medical and recreational compounds.

Sharon R Sznitman, Lianna Pinsky-Talbi, Maisar Salameh, Taleb Moed, Yedidia Bentur,

BACKGROUND:Increasing use of cannabis for medical and recreational purposes has augmented concerns about associated poisoning, and specifically pediatric and adolescent poisonings. Synthetic cannabinoids, often marketed as cannabis replacement, have recently emerged and knowledge and awareness of their toxic effects is growing. The objective of this study was to characterize and ... Read more >>

Int. J. Drug Policy (The International journal on drug policy)
[2020, 77:102711]

Cited: 0 times

View full text PDF listing >>



Cannabis Sativa Revisited-Crosstalk between microRNA Expression, Inflammation, Oxidative Stress, and Endocannabinoid Response System in Critically Ill Patients with Sepsis.

Anca Raluca Dinu, Alexandru Florin Rogobete, Tiberiu Bratu, Sonia Elena Popovici, Ovidiu Horea Bedreag, Marius Papurica, Lavinia Melania Bratu, Dorel Sandesc,

Critically ill patients with sepsis require a multidisciplinary approach, as this situation implies multiorgan distress, with most of the bodily biochemical and cellular systems being affected by the condition. Moreover, sepsis is characterized by a multitude of biochemical interactions and by dynamic changes of the immune system. At the moment, ... Read more >>

Cells (Cells)
[2020, 9(2):]

Cited: 0 times

View full text PDF listing >>



Advertisement

Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.

A P Liu, Q H Yuan, B Zhang, L Yang, Q W He, K Chen, Q S Liu, Z Li, J Zhan,

Septic lung injury is one of main causes of high mortality in severe patients. Inhibition of excessive inflammatory response is considered as an effective strategy for septic lung injury. Previous studies have shown that cannabinoid receptor 2 (CB2), a G protein-coupled receptor, play an important role in immunosuppression. Whether CB2 ... Read more >>

Cell. Signal. (Cellular signalling)
[2020, 69:109556]

Cited: 0 times

View full text PDF listing >>



New psychoactive substances (NPS) in the Netherlands: occurrence in forensic drug samples, consumer drug samples and poisons center exposures between 2013 and 2017.

Laura Hondebrink, Johanna J Nugteren-van Lonkhuyzen, Claudine C Hunault, Jorrit van den Berg, Daan van der Gouwe, Antoinette J H P van Riel,

Addiction (Addiction (Abingdon, England))
[2020, 115(4):716-725]

Cited: 0 times

View full text PDF listing >>



The ameliorating effect of cannabinoid type 2 receptor activation on brain, lung, liver and heart damage in cecal ligation and puncture-induced sepsis model in rats.

Murat Çakır, Suat Tekin, Aslı Okan, Pınar Çakan, Züleyha Doğanyiğit,

Uncontrolled infection and increased inflammatory mediators might cause systemic inflammatory response. It is already known that Cannabinoid Type 2 (CB2) receptors, which are commonly expressed in immune cells and in many other tissues, have an effect on the regulation of immune response. In the present study of ours, the effects ... Read more >>

Int. Immunopharmacol. (International immunopharmacology)
[2020, 78:105978]

Cited: 0 times

View full text PDF listing >>



The Cannabinoid WIN 55,212-2 Reduces Delayed Neurologic Sequelae After Carbon Monoxide Poisoning by Promoting Microglial M2 Polarization Through ST2 Signaling.

Jing-Jing Du, Zhi-Qin Liu, Yue Yan, Jing Xiong, Xiao-Tao Jia, Zheng-Li Di, Jing-Jing Ren,

Delayed neurologic sequelae (DNS) are among the most serious complications of carbon monoxide (CO) poisoning caused partly by elevated neuroinflammation. WIN 55,212-2, a non-selective agonist of cannabinoid receptors, has been demonstrated to have anti-inflammatory properties in various brain disorders. The anti-inflammatory action of WIN 55,212-2 is potentially associated with driving ... Read more >>

J. Mol. Neurosci. (Journal of molecular neuroscience : MN)
[2020, 70(3):422-432]

Cited: 0 times

View full text PDF listing >>



Cannabis Sativa Revisited - Crosstalk between microRNAs Expression, Inflammation, Oxidative Stress and Endocannabinoid Response System in Critically Ill Patients with Sepsis

Alexandru Florin Rogobete, Tiberiu Bratu, Ovidiu Horea Bedreag, Marius Papurica, Sonia Elena Popovici, Dorel Sandesc,

Critically ill patients with sepsis require a multidisciplinary approach, as this situation implies multiorgan distress, with most of the bodily biochemical and cellular systems being affected by the condition. Moreover, sepsis is characterized by a multitude of biochemical interactions and by dynamic changes of the immune system. At the moment, ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Cannabinoid1 (CB-1) receptor antagonists: a molecular approach to treating acute cannabinoid overdose.

Phil Skolnick, Roger Crystal,

The legalization of cannabis for both recreational and medical use in the USA has resulted in a dramatic increase in the number of emergency department visits and hospital admissions for acute cannabinoid overdose (also referred to as cannabis intoxication and cannabis poisoning). Both "edibles" (often sold as brownies, cookies, and ... Read more >>

J Neural Transm (Vienna) (Journal of neural transmission (Vienna, Austria : 1996))
[2020, 127(2):279-286]

Cited: 0 times

View full text PDF listing >>



Endocannabinoid System in the Airways.

Turgut Emrah Bozkurt,

Cannabinoids and the mammalian endocannabinoid system is an important research area of interest and attracted many researchers because of their widespread biological effects. The significant immune-modulatory role of cannabinoids has suggested their therapeutic use in several inflammatory conditions. Airways are prone to environmental irritants and stimulants, and increased inflammation is ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2019, 24(24):]

Cited: 0 times

View full text PDF listing >>



Rapid identification of MDMB-CHMINACA metabolites using Zebrafish and Human Liver microsomes as the Biotransformation system by LC-QE-HF-MS.

Duo-Qi Xu, Yong Dai, Wen-Fang Zhang, Ji-Fen Wang, Yan-Yan Wang, Ying Zhang, Qiao-Lin Zhao, Xiao Li,

MDMB-CHMINACA is a newly synthetic cannabinoid which scoped in NMS Lab, USA. Since there are currently no published data on MDMB-CHMINACA metabolism, we aimed to identify its biotransformation pathways and major metabolites. Liquid chromatography Q-Extractive HF Hybrid Quadrupole-Orbitrap mass spectrometry (LC-QE-HF-MS) using full scan positive ion mode and targeted MS/MS ... Read more >>

J Anal Toxicol (Journal of analytical toxicology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



An outbreak of severe coagulopathy from synthetic cannabinoids tainted with Long-Acting anticoagulant rodenticides.

Jason M Devgun, Arkady Rasin, Theresa Kim, Mark B Mycyk, Sean M Bryant, Michael S Wahl, Carol DesLauriers, Livia Navon, Erin D Moritz, Trevonne M Thompson, Henry D Swoboda, Jenny Lu, Steven E Aks,

Objective: To describe a large regional poison center's experience managing an outbreak of long-acting anticoagulant rodenticide (LAAR) poisoning associated with synthetic cannabinoid (SC) use.Methods: This is a retrospective review of exposures reported to the Illinois Poison Center between March 10 and August 1, 2018. All cases coded as exposure to ... Read more >>

Clin Toxicol (Phila) (Clinical toxicology (Philadelphia, Pa.))
[2019, :1-8]

Cited: 0 times

View full text PDF listing >>



Poisoning with Drugs of Abuse: Identification and Management.

Lekhansh Shukla, Deepak S Ghadigaonkar, Pratima Murthy,

Substances of abuse include alcohol, nicotine, cannabinoids, opioids, sedatives, volatile solvents, stimulants, and hallucinogens. With the increasing prevalence of drug abuse in India, intensivists are likely to encounter more cases of intentional and accidental poisoning due to drugs of abuse. We aim to sensitize the intensivists to challenges involved in ... Read more >>

Indian J Crit Care Med (Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine)
[2019, 23(Suppl 4):S296-S304]

Cited: 0 times

View full text PDF listing >>



Effects of vitamin K1 treatment on plasma concentrations of long-acting anticoagulant rodenticide enantiomers following inhalation of contaminated synthetic cannabinoids.

Douglas L Feinstein, Daniel G Nosal, Swetha Ramanathan, Jifang Zhou, Luying Chen, Ronald C Hershow, Richard B van Breemen, Erik Wright, John W Hafner, Israel Rubinstein,

Background: An outbreak of synthetic cannabinoid (SC)-associated coagulopathy and bleeding in Illinois, USA was determined to be due to inhalation of SC contaminated with brodifacoum (BDF), difenacoum (DiF), and bromadiolone (BDL), highly potent long-acting anticoagulant rodenticides (LAARs). Treatment with high-dose vitamin K1 (VK1) prevented mortality; however, plasma LAAR levels were ... Read more >>

Clin Toxicol (Phila) (Clinical toxicology (Philadelphia, Pa.))
[2019, :1-9]

Cited: 0 times

View full text PDF listing >>



Superwarfarin (Long-Acting Anticoagulant Rodenticides) Poisoning: from Pathophysiology to Laboratory-Guided Clinical Management.

Yeow-Kuan Chong, Tony Wing-Lai Mak,

Superwarfarins are long-acting anticoagulant rodenticides developed from warfarin. The mechanism of action is by inhibition of vitamin K epoxide reductase, resulting in the inability of the body to recycle vitamin K. Deficiency of vitamin K thereafter leads to inability for the body to synthesise vitamin K-dependent coagulation factors, factor II, ... Read more >>

Clin Biochem Rev (The Clinical biochemist. Reviews)
[2019, 40(4):175-185]

Cited: 1 time

View full text PDF listing >>



Acute Cannabis Toxicity.

Kei U Wong, Carl R Baum,

The change in legal status of cannabis (the botanical species Cannabis sativa, commonly known as marijuana) in the United States has had significant impact on pediatric drug exposures. In states with decriminalization of recreational and medicinal use of cannabis, emergency department visits and poison control center calls for unintentional pediatric ... Read more >>

Pediatr Emerg Care (Pediatric emergency care)
[2019, 35(11):799-804]

Cited: 0 times

View full text PDF listing >>



Critical issues in alcohol and drugs of abuse testing.

Raka Jain,

Indian J. Med. Res. (The Indian Journal of Medical Research)
[2019, 150(6):646-647]

Cited: 0 times

View full text PDF listing >>



A Case of Status Epilepticus and Transient Stress Cardiomyopathy Associated with Smoking the Synthetic Psychoactive Cannabinoid, UR-144.

Sarah Al Fawaz, Mohammad Al Deeb, James L Huffman, Naji A Al Kholaif, Fiona Garlich, Ryan Chuang,

BACKGROUND Synthetic cannabinoids have a higher affinity for the cannabinoid receptors CB1 and CB2 than natural cannabinoids. Their use can be associated with cardiovascular disease and neurological complications. A case is reported of status epilepticus and stress cardiomyopathy following the recreational use of the synthetic cannabinoid, UR-144. CASE REPORT A ... Read more >>

Am J Case Rep (The American journal of case reports)
[2019, 20:1902-1906]

Cited: 0 times

View full text PDF listing >>



Priming primary care providers to engage in evidence-based discussions about cannabis with patients.

Devan Kansagara, William C Becker, Chelsea Ayers, Jeanette M Tetrault,

Cannabis use has become increasingly common in the U.S. in recent years, with legalization for medical and recreational purposes expanding to more states. With this increase in use and access, providers should be prepared to have more conversations with patients about use. This review provides an overview of cannabis terminology, ... Read more >>

Addict Sci Clin Pract (Addiction science & clinical practice)
[2019, 14(1):42]

Cited: 0 times

View full text PDF listing >>



Comparative Evaluation of Combinatory Interaction between Endocannabinoid System Compounds and Poly-L-lysine against Streptococcus mutans Growth and Biofilm Formation.

Mark Feldman, Ronit Sionov, Reem Smoum, Raphael Mechoulam, Isaac Ginsburg, Doron Steinberg,

Endocannabinoid/endocannabinoid-like (EC/EC-like) are natural endogenous compounds which have been found to affect MRSA pathogenicity. Our previous studies showed that EC/EC-like was able to impair staphylococcal biofilm formation and maintenance as well as to alter biofilm-associated virulence factors. In the present study, we investigated the combinatory effect of the selected EC/EC-like ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:7258380]

Cited: 0 times

View full text PDF listing >>



Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells.

Shivani Sachdev, Rochelle Boyd, Natasha L Grimsey, Marina Santiago, Mark Connor,

Background:Synthetic cannabinoids are a commonly used class of recreational drugs that can have significant adverse effects. There have been sporadic reports of co-consumption of illicit drugs with rodenticides such as warfarin and brodifacoum (BFC) over the past 20 years but recently, hundreds of people have been reported to have been ... Read more >>

PeerJ (PeerJ)
[2019, 7:e7733]

Cited: 0 times

View full text PDF listing >>



The Bridge Between Classical and "Synthetic"/Chemical Psychoses: Towards a Clinical, Psychopathological, and Therapeutic Perspective.

Laura Orsolini, Stefania Chiappini, Duccio Papanti, Domenico De Berardis, John M Corkery, Fabrizio Schifano,

The critical spread and dissemination of novel psychoactive substances (NPS), particularly among the most vulnerable youngsters, may pose a further concern about the psychotic trajectories related to the intake of new synthetic drugs. The psychopathological pattern of the "new psychoses" appears to be extremely different from the classical presentation. Therefore, ... Read more >>

Front Psychiatry (Frontiers in Psychiatry)
[2019, 10:851]

Cited: 0 times

View full text PDF listing >>



Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats with Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism.

Patryk Remiszewski, Iwona Jarocka-Karpowicz, Michał Biernacki, Anna Jastrząb, Eberhard Schlicker, Marek Toczek, Ewa Harasim-Symbor, Anna Pędzińska-Betiuk, Barbara Malinowska,

We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate (HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats. Hypertension was connected with increases in cardiac and plasma markers of lipid peroxidation in both models, whereas cardiac endocannabinoid levels decreased in SHR and increased in DOCA-salt. ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(4):]

Cited: 0 times

View full text PDF listing >>



Acute toxic kidney injury.

Nadezda Petejova, Arnost Martinek, Josef Zadrazil, Vladimir Teplan,

Substances toxic to the kidney are legion in the modern world. The sheer number and variety, their mutual interactions and, metabolism within the body are a challenge to research. Moreover, the kidney is especially prone to injury owing to its physiology. Acute kidney injury (AKI) induced by poisonous or primarily ... Read more >>

Ren Fail (Renal failure)
[2019, 41(1):576-594]

Cited: 1 time

View full text PDF listing >>



Priority Considerations for Medicinal Cannabis-Related Research.

Marcel O Bonn-Miller, Charles V Pollack, David Casarett, Richard Dart, Mahmoud ElSohly, Larry Good, Manuel Guzmán, Lumír Hanuš, Kevin P Hill, Marilyn A Huestis, Eric Marsh, Susan Sisley, Nancy Skinner, Judith Spahr, Ryan Vandrey, Eugene Viscusi, Mark A Ware, Donald Abrams,

Cannabis Cannabinoid Res (Cannabis and cannabinoid research)
[2019, 4(3):139-157]

Cited: 0 times

View full text PDF listing >>



Cannabis intoxication after accidental ingestion in infants: urine and plasma concentrations of Δ-9-tetrahydrocannabinol (THC), THC-COOH and 11-OH-THC in 10 patients.

Charles Guidet, Matthieu Gregoire, Alexiane Le Dreau, Benedicte Vrignaud, Guillaume Deslandes, Catherine Monteil-Ganière,

Introduction: Accidental cannabis poisoning after oral ingestion in infants is an emerging cause of intoxication with well-known clinical aspects but few data exist regarding the levels of cannabinoids in plasma and urine. Here, we present data on the concentrations of Δ-9-tetrahydrocannabinol (THC) and metabolites in plasma and/or urine in 10 ... Read more >>

Clin Toxicol (Phila) (Clinical toxicology (Philadelphia, Pa.))
[2020, 58(5):421-423]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
1.6683 s