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The C. elegans pseudogene sspt-16 (F55A3.7) is required to safeguard germ cells against reprogramming.

Andreas Ofenbauer, Clara Maria Kraus, Baris Tursun,

We recently identified FAcilitates Chromatin Transcription (FACT) as a reprogramming barrier of transcription factor (TF) mediated conversion of germ cells into neurons in <i>C. elegans</i>. FACT is a conserved heterodimer consisting of SPT16 and SSRP1 in mammals. Duplication events during evolution in <i>C. elegans</i> generated two SSRP1 homologs named HMG-3 ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Recombination and biased segregation of mitochondrial genomes during crossing and meiosis of different Schizosaccharomyces pombe strains.

Stephan Kamrad, María Rodríguez-López, Shoumit Dey, Mimoza Hoti, Henry Wallace, Markus Ralser, Jürg Bähler,

During meiosis, tethering of parental mitochondria to opposite cell poles inhibits the mixing of mitochondria with different genomes and ensures uniparental inheritance in thestandard laboratory strain of fission yeast. We here investigate mitochondrial inheritance in crosses between natural isolates using tetrad dissection and next-generation sequencing. We find that colonies grown ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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CRISPR-edit point mutant allele detection (CEPAD)-PCR method for rapid screening of CRISPR edited point mutations.

Kenneth Trimmer, Swathi Arur,

CRISPR-Cas9 mediated genome editing is widely used for generating genetic lesions in <i>C. elegans</i>. Detection of single-site mutations in F1 progeny after CRISPR-Cas9 injections is currently labor intensive due to lack of a single step PCR-based detection method. Here we present CEPAD-PCR, an allele-specific PCR detection method based on generating ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Pyrogallol induces oxidative stress defects in the fission yeast S. pombe.

Nafees Ahamad, Simmi Anjum, Shakil Ahmed,

Apart from the beneficial roles of pyrogallol in industries, it also tends to produce free radicals that trigger apoptosis in human cells. In this study, we checked the toxic effect of pyrogallol in fission yeast <i>S. pombe</i> cells. We observed that the wild type and <i>wat1/pop3</i> delete cells were unable ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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The ISWI chromatin remodelling factor NURF is not required for mitotic male X chromosome organisation.

So Yeon Kwon, Boyun Jang, Paul Badenhorst,

The nucleosome remodelling factor (NURF) is an ISWI-class ATP-dependent chromatin remodeling enzyme required both for gene expression and higher order chromatin organisation<i>.</i> NURF binds to histone modifications that decorate the <i>Drosophila</i> polytene male X chromosome and is required to maintain correct organisation of this chromosome. NURF mutants exhibit distorted and ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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A genome-wide screen in Saccharomyces cerevisiae identifies Tannic Acid-sensitive mutants.

Emily M Pilc, Shriie Ganesh, Oliver Kerscher,

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits.

Steven J Marygold, Nazif Alic, David S Gilmour, Savraj S Grewal,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Spontaneous neoplasia in the western clawed frog Xenopus tropicalis.

Makoto Suzuki, Takeshi Igawa, Nanoka Suzuki, Hajime Ogino, Haruki Ochi,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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The cadmium-responsive gene, cdr-6, does not influence Caenorhabditis elegans responses to exogenous zinc.

Kathryn S Evans, Erik C Andersen,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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A toolkit of tagged glp-1 alleles reveals strong glp-1 expression in the germline, embryo, and spermatheca.

Erika B Sorensen, Hannah S Seidel, Sarah L Crittenden, Joseph H Ballard, Judith Kimble,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 1 time

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Vennter - An interactive analysis tool for WormBase interaction data using Venn diagrams.

Jaehyoung Cho, Sibyl Gao, Lincoln Stein, Paul W Sternberg,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 0 times

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Oncogenic Ras cooperates with knockdown of the tumor suppressor Lkb1 by RNAi to override organ size limits in Drosophila wing tissue.

Briana Brown Rackley, Evan Kiely, Chang-Soo Seong, Manali Rupji, Melissa Gilbert-Ross,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Endogenous expression of UNC-59/Septin in C. elegans.

David Chen, Eric Hastie, David Sherwood,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

Cited: 0 times

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The root hair defective phenotype of Arabidopsis thaliana Pol IV subunit mutant nrpd1a-3 is associated with a deletion in RHD6.

Rakesh David, R Kortschak, Iain Searle,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

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Three C. elegans srf-6 mutants carry nsy-1 mutations (srf-6 is nsy-1 I).

Nicholas Van Sciver, Jennifer Pulkowski, Samuel Politz,

MicroPubl Biol (microPublication biology)
[2019, 2019:]

Cited: 3 times

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2018 Update on Protein-Protein Interaction Data in WormBase.

Jaehyoung Cho, Christian Grove, Kimberly Van Auken, Juancarlos Chan, Sibyl Gao, Paul Sternberg,

MicroPubl Biol (microPublication biology)
[2018, 2018:]

Cited: 1 time

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GFP::PCN-1 does not reliably mark S phase in C. elegans adult germline progenitor zone cells.

Tokiko Uruta, Swathi Arur,

MicroPubl Biol (microPublication biology)
[2018, 2018:]

Cited: 0 times

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SapTrap assembly of repair templates for Cas9-triggered homologous recombination with a self-excising cassette.

Daniel Dickinson, Mark Slabodnick, Alicia Chen, Bob Goldstein,

MicroPubl Biol (microPublication biology)
[2018, 2018:]

Cited: 7 times

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Microfluidic EPG recordings show striking pharyngeal pumping phenotype in a C. elegans Alzheimer's disease model.

Janis C Weeks, Kristin J Robinson, Benedicta Wanjeri, Philip F Copenhaver, William M Roberts,

MicroPubl Biol (microPublication biology)
[2016, 2016:]

Cited: 0 times

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Pelvic lymph node dissection in high-risk prostate cancer.

Luciano Haiquel, Xavier Cathelineau, Rafael Sanchez-Salas, Petr Macek, Fernando Secin,

<h4>Introduction</h4>The therapeutic role of pelvic lymph node dissection (PLND) in prostate cancer (PCa) is unknown due to absence of randomized trials.<h4>Objective</h4>to present a critical review on the therapeutic benefits of PLND in high risk localized PCa patients.<h4>Materials and methods</h4>A search of the literature on PLND was performed using PubMed, Cochrane, ... Read more >>

Int Braz J Urol (International braz j urol : official journal of the Brazilian Society of Urology)
[2022, 48:]

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Research advances on how metformin improves memory impairment in "chemobrain".

Ahmad Alhowail, Sridevi Chigurupati,

Cognitive impairment caused by chemotherapy, referred to as "chemobrain," is observed in approximately 70% of cancer survivors. However, it is not completely understood how chemotherapy induces cognitive dysfunction, and clinical treatment strategies for this problem are lacking. Metformin, used as a first-line treatment for type 2 diabetes mellitus, is reported ... Read more >>

Neural Regen Res (Neural regeneration research)
[2022, 17(1):15-19]

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Neuronal pentraxin II (NPTX2) hypermethylation promotes cell proliferation but inhibits cell cycle arrest and apoptosis in gastric cancer cells by suppressing the p53 signaling pathway.

Guofeng Xu, Linfeng Fan, Shufeng Zhao, Canhui OuYang,

Gastric cancer is a considerable health burden worldwide. DNA methylation, a major epigenetic phenomenon, is closely related to the pathogenesis of cancer. Neuronal pentraxin II (NPTX2) has been found to be hypermethylated in several cancers such as glioblastoma and pancreatic cancer. However, the roles of NPTX2 in gastric cancer have ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1311-1323]

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Long noncoding RNA ENST00000508435 promotes migration of breast cancer via FXR 1.

Luying Li, Youping Jin, Xue Wang, Li Wang, Yangbai Sun, Yihong Luo, Xiaojian Ni, Qi Lu, Wenbo Wei, Xiuling Zhi, Jerry Yu, Wei Zhu, Ping Zhou,

LncRNA plays a critical role in tumor progression. However, the role it executes in breast cancer is still unclear. Here, we report a newly discovered lncRNA, <i>ENST00000508435</i>, which could be remarkably up-regulated in breast cancer cells and tissues. We found that the expression of <i>ENST00000508435</i> was positively correlated with tumor ... Read more >>

Cell Adh Migr (Cell adhesion & migration)
[2021, 15(1):140-151]

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Long noncoding RNA MST1P2 promotes cervical cancer progression by sponging with microRNA miR-133b.

Rongrong Xu, Xiaoyue Zhang, Yan Xu, Junqin Wang, Zhihui Li, Xiaoming Cui,

Long noncoding RNA (lnc RNA) is aberrant expressed in many kinds of tumors and may be concerned with the occurrence and progression of tumors. Lnc RNA MST1P2 is increased in cervical cancer (CC), but its mechanism in CC has not been clarified. In this study, RT-qPCR was employed to analyze ... Read more >>

Bioengineered (Bioengineered)
[2021, 12(1):1851-1860]

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Visfatin and global histone H3K9me levels in colon cancer.

Eman A Al Abdulsalam, Rowyda N Al Harithy,

<h4>Background</h4>Visfatin is considered to be a biomarker in various types of cancers, including colon cancer. Moreover, evidence for epigenetic mechanism must be reported for an association between visfatin level and colon cancer. Therefore, this study was designed to investigate the status of visfatin expression and the global histone three modifications ... Read more >>

Ann Med (Annals of medicine)
[2021, 53(1):647-652]

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