Full Text Journal Articles about
CNS Cryptococcosis in HIV

Advertisement

Find full text journal articles






HIV-1 Central Nervous System Compartmentalization and Cytokine Interplay in Non-subtype B HIV-1 Infections in Nigeria and Malawi.

Olubusuyi Moses Adewumi, Elena Dukhovlinova, Nathan Y Shehu, Shuntai Zhou, Olivia D Council, Maxwell O Akanbi, Babafemi Taiwo, Adesola Ogunniyi, Kevin Robertson, Cecilia Kanyama, Mina C Hosseinipour, Ronald Swanstrom,

HIV-1 compartmentalization in the central nervous system (CNS) and its contribution to neurological disease have been well documented. Previous studies were conducted among people infected with subtypes B or C where CNS compartmentalization has been observed when comparing viral sequences in the blood to virus in cerebrospinal fluid (CSF). However, ... Read more >>

AIDS Res. Hum. Retroviruses (AIDS research and human retroviruses)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Failure of multiplex meningitis/encephalitis (ME) NAT during cryptococcal meningitis in solid organ recipients.

B Pilmis, M-E Bougnoux, R Guery, Y Senghor, A Le Monnier, F Lanternier, S Bretagne, A Alanio, O Lortholary,

Cryptococcal meningitis is a severe cause of central nervous system infections among immunocompromised solid organ transplant (SOT) patients. While new diagnostic methods as multiplex meningitis/encephalitis (ME) NAT (nucleic acid test) are increasingly used as a first-line tool in hospital practice, data in HIV-negative patients including SOT remain scarce. We report ... Read more >>

Transpl Infect Dis (Transplant infectious disease : an official journal of the Transplantation Society)
[2020, :e13263]

Cited: 0 times

View full text PDF listing >>



Advertisement

Educational Case: Opportunistic Infections of the Central Nervous System.

Steven Toffel, Lymaries Velez, Jorge Trejo-Lopez, Stacy G Beal, Jesse L Kresak,

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and ... Read more >>

Acad Pathol (Academic pathology)
[2020, 7:2374289520901809]

Cited: 0 times

View full text PDF listing >>



Chemokine and Cytokine Cascade Caused by Skewing of the Th1-Th2 Balance Is Associated with High Intracranial Pressure in HIV-Associated Cryptococcal Meningitis.

Lijun Xu, Yongzheng Guo, Yizhou Zhao, Yufan Xu, Xiuming Peng, Zongxing Yang, Ran Tao, Ying Huang, Yan Xu, Yaokai Chen, Biao Zhu,

Purpose:Serum cytokines/chemokines play important roles in cryptococcal meningitis, but it is unclear whether cytokines/chemokines in cerebrospinal fluid (CSF) contribute to high intracranial pressure (HICP) in HIV-associated cryptococcal meningitis (HCM). Methods:CSF cytokines/chemokines were assayed in 17 HIV-uninfected patients, 26 HIV-infected patients without CNS infection, and 39 HCM patients at admission. Principal ... Read more >>

Mediators Inflamm. (Mediators of inflammation)
[2019, 2019:2053958]

Cited: 0 times

View full text PDF listing >>



Disseminated cryptococcosis in an immunocompetent patient.

Rahul Bollam, Mohamed Yassin, Tung Phan,

Cryptococcosis is an important opportunistic infection. It is the third most common invasive fungal infection in solid organ transplant recipients. The primary organ affected is the lungs, but infection of the central nervous system and other organ systems are also seen. Here we reported a case of disseminated cryptococcosis in ... Read more >>

Respir Med Case Rep (Respiratory medicine case reports)
[2020, 30:101034]

Cited: 0 times

View full text PDF listing >>



Triple infection with Cryptococcus, varicella-zoster virus, and Mycobacterium abscessus in a patient with anti-interferon-gamma autoantibodies: a case report.

Pongprueth Rujirachun, Jirath Sangwongwanich, Methee Chayakulkeeree,

BACKGROUND:The most common infection in patients positive for anti-interferon-gamma autoantibodies (anti-IFN-γ AAbs) is disseminated nontuberculous mycobacterial (dNTM) infection. Here, we report a rare case of triple infection caused by Cryptococcus, varicella-zoster virus (VZV), and nontuberculous mycobacterium in a patient with anti-IFN-γ AAbs. CASE PRESENTATION:A 53-year-old Thai man presented with a ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2020, 20(1):232]

Cited: 0 times

View full text PDF listing >>



An exceptional case report of disseminated cryptococcosis in a hitherto immunocompetent patient.

Tatjana Adzic-Vukicevic, Muge Cevik, Jasmina Poluga, Jelena Micic, Salvatore Rubino, Bianca Paglietti, Aleksandra Barac,

Cryptococcosis is an opportunistic fungal infection causes significant disease predominantly in immunocompromised patients. Here we present an excepcional case of disseminated cryptococcosis with pulmonary and cerebral involvement in an immunocompetent patient with no apparent predisposing factors at the time of hospital admission. We described a case of an apparently immunocompetent ... Read more >>

Rev. Inst. Med. Trop. Sao Paulo (Revista do Instituto de Medicina Tropical de São Paulo)
[2020, 62:e3]

Cited: 0 times

View full text PDF listing >>



Cryptococcal meningitis and immune reconstitution inflammatory syndrome in a pediatric patient with HIV after switching to second line antiretroviral therapy: a case report.

Ssegujja Boniface Joseph Otto, Paul E George, Rebecca Mercedes, Nicolette Nabukeera-Barungi,

BACKGROUND:Cryptococcal meningitis (CCM) is a common and deadly disease among HIV-infected patients. Notable about CCM is its association with the immune reconstitution inflammatory syndrome (IRIS). Though it has been posited a switch from first to second-line antiretroviral therapy (ART) can induce CCM IRIS, a case presentation of CCM IRIS has ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2020, 20(1):68]

Cited: 0 times

View full text PDF listing >>



A Multicenter, Longitudinal Cohort Study of Cryptococcosis in Human Immunodeficiency Virus-negative People in the United States.

Kieren A Marr, Yifei Sun, Andrej Spec, Na Lu, Anil Panackal, John Bennett, Peter Pappas, Darin Ostrander, Kausik Datta, Sean X Zhang, Peter R Williamson, ,

BACKGROUND:Cryptococcosis is increasingly recognized in people without human immunodeficiency virus (HIV). METHODS:A multicenter, prospective cohort study was performed in 25 US centers. Consenting patients were prospectively followed for ≤2 years. Neurological morbidities were assessed with longitudinal event depiction and functional scores (Montreal Cognitive Assessment [MoCA]). Risks of death were analyzed ... Read more >>

Clin. Infect. Dis. (Clinical infectious diseases : an official publication of the Infectious Diseases Society of America)
[2020, 70(2):252-261]

Cited: 2 times

View full text PDF listing >>



Early career interview: Nathan Bahr.

Nathan Bahr,

Nathan Bahr is an Assistant Professor in infectious disease research at the University of Kansas (USA). He works in global health, tuberculosis meningitis, cryptococcal meningitis and histoplasmosis. He was one of three finalists of the 2019 Future Science Future Star Award. Here, he tells us about his career to-date. ... Read more >>

Future Sci OA (Future science OA)
[2020, 6(3):FSO444]

Cited: 0 times

View full text PDF listing >>



Cryptococcal Antigen Testing in an Integrated Medical System: Eastern Wisconsin.

Marianne Klumph, Brian Hoeynck, Dennis J Baumgardner,

Cryptococcosis is a serious environmentally acquired endemic fungal infection commonly associated with immunocompromised hosts. Little is known regarding frequency or distribution in Wisconsin. We explored the geodemographic and clinical features of patients tested with cryptococcal antigen tests (CrAg) - previously shown to be >90% sensitive and >90% specific - within ... Read more >>

J Patient Cent Res Rev (Journal of patient-centered research and reviews)
[2020, 7(1):57-62]

Cited: 0 times

View full text PDF listing >>



Postoperative Antifungal Treatment of Pulmonary Cryptococcosis in Non-HIV-Infected and Non-Transplant-Recipient Patients: A Report of 110 Cases and Literature Review.

Shuo Wei, Xin Su, Yun-Hu Pan, Yuan-Yuan Zheng, Xiao-Wen Dong, Xiao-Hua Hu, Fan Wu, Yi Shi,

Background:To explore the efficacy of postoperative antifungal treatment for preventing the recurrence of pulmonary cryptococcosis (PC) and occurrence of cryptococcal meningitis (CM), a retrospective study was conducted in 112 hospitalized PC patients with or without antifungal treatment following surgery. Methods:The treatment failure rate, PC recurrence rate, and CM incidence were ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(1):ofaa004]

Cited: 0 times

View full text PDF listing >>



Impaired consciousness and decreased glucose concentration of CSF as prognostic factors in immunocompetent patients with cryptococcal meningitis.

Chen Zhang, Zheren Tan, Fafa Tian,

BACKGROUND:Cryptococcal meningitis (CM) is the most common fungal infection of the central nervous system and has high morbidity and mortality. Almost studies about prognostic factors have largely focused on the immunocompromised population rather than immunocompetent patients. So that we sought to conduct a retrospective study to determine prognostic factors which ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2020, 20(1):69]

Cited: 0 times

View full text PDF listing >>



Management of HIV-infected patients in the intensive care unit.

François Barbier, Mervin Mer, Piotr Szychowiak, Robert F Miller, Éric Mariotte, Lionel Galicier, Lila Bouadma, Pierre Tattevin, Élie Azoulay,

The widespread use of combination antiretroviral therapies (cART) has converted the prognosis of HIV infection from a rapidly progressive and ultimately fatal disease to a chronic condition with limited impact on life expectancy. Yet, HIV-infected patients remain at high risk for critical illness due to the occurrence of severe opportunistic ... Read more >>

Intensive Care Med (Intensive care medicine)
[2020, 46(2):329-342]

Cited: 0 times

View full text PDF listing >>



Cerebral Lupus and Cryptococcal Meningitis in a Pregnant Woman.

Ching Soong Khoo, Marsilla Mariaty Marzukie, Soo Shu Yap, Wan Nur Nafisah Wan Yahya, Hui Jan Tan,

Systemic lupus erythematosus (SLE) is a chronic autoimmune and multisystem disorder, which frequently affects young women. During pregnancy, SLE flares could occur up to 65%, with renal and hematological manifestations being the most common. However, reports on neuropsychiatric lupus in pregnant women are scarce. We herein report a 26-year-old lupus ... Read more >>

J Neurosci Rural Pract (Journal of neurosciences in rural practice)
[2020, 11(1):183-186]

Cited: 0 times

View full text PDF listing >>



Cryptococcus gattii infection in an immunocompetent host in Greece.

Marina Andreou, Massimo Cogliati, Fevronia Kolonitsiou, Charalampos Stroumpos, Vasiliki Stamouli, Panagiota Ravazoula, Dimitrios Siagris, Helen Papadogeorgaki, Myrto Christofidou, Alexandra Lekkou,

We report a case of a 31-year-old otherwise healthy female with pulmonary cryptococcoma along with cryptococcal meningitis due to Cryptococcus gattii molecular type VGI, in Greece. Combined antifungal treatment and surgical excision of pulmonary cryptococcoma yielded a good response. ... Read more >>

Med Mycol Case Rep (Medical mycology case reports)
[2020, 27:1-3]

Cited: 0 times

View full text PDF listing >>



An AIDS patient with urine retention.

Lijun Xu, Ran Tao, Qiyu Zhao, Jinlin Cheng, Biao Zhu,

BACKGROUND:Cryptococcal prostatitis is a rare clinical disease and has never been reported in China. CASE PRESENTATION:We report on a male HIV-infected patient with pulmonary and prostate cryptococcosis that was misdiagnosed (as tuberculosis) and delayed diagnosed. Although the patients accepted anti-fungal treatment and anti-retroviral treatment finally, the physician's mistakes reflect the ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2019, 19(1):1051]

Cited: 0 times

View full text PDF listing >>



1404. The FilmArray Meningitis/Encephalitis (FA ME) May Be of Higher Yield in the Immunocompromised Patient Population.

Nirja Mehta, Jesse T Jacob, Christina Dean, Zanthia Wiley, Eileen Burd, Colleen Kraft,

AbstractBackgroundThe FilmArray® Meningitis/Encephalitis (FA ME) panel is a PCR-based assay that rapidly detects 14 pathogens directly from CSF specimens. After the introduction of this assay at our institution, there was a steady increase in requests for use; however, the positivity rate remained stable. We sought to understand the characteristics of ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S511-S511]

Cited: 0 times

View full text PDF listing >>



Seizures in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: Predictors and Outcomes.

Katelyn A Pastick, Ananta S Bangdiwala, Mahsa Abassi, Andrew G Flynn, Bozena M Morawski, Abdu K Musubire, Prosperity C Eneh, Charlotte Schutz, Kabanda Taseera, Joshua Rhein, Kathy Huppler Hullsiek, Melanie R Nicol, Jose E Vidal, Noeline Nakasujja, Graeme Meintjes, Conrad Muzoora, David B Meya, David R Boulware,

Background:Seizures commonly occur in patients with cryptococcal meningitis, yet risk factors and outcomes related to seizures are not well described. Methods:We performed post hoc analyses on participants prospectively enrolled in 3 separate human immunodeficiency virus (HIV)-associated cryptococcal meningitis clinical trials during 2010-2017. Documentation of seizures at presentation or during hospitalization ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(11):ofz478]

Cited: 0 times

View full text PDF listing >>



B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis.

Samuel Okurut, David B Meya, Freddie Bwanga, Joseph Olobo, Michael A Eller, Fatim Cham-Jallow, Paul R Bohjanen, Harsh Pratap, Brent E Palmer, Katharine H Hullsiek, Yukari C Manabe, David R Boulware, Edward N Janoff,

Activated B cells modulate infection by differentiating into pathogen-specific antibody-producing effector plasmablasts/plasma cells, memory cells, and immune regulatory B cells. In this context, the B cell phenotypes that infiltrate the central nervous system during human immunodeficiency virus (HIV) and cryptococcal meningitis coinfection are ill defined. We characterized clinical parameters, mortality, ... Read more >>

Infect. Immun. (Infection and immunity)
[2020, 88(3):]

Cited: 0 times

View full text PDF listing >>



Clinical insights and epidemiology of central nervous system infection due to Cryptococcus neoformans/gattii species complexes: A prospective study from South India.

Shayanki Lahiri, Netravathi Manjunath, Maya Bhat, Ferry Hagen, Veenakumari H Bahubali, Marimuthu Palaniappan, Sayani Maji, Nagarathna Chandrashekar,

In the last two decades, central nervous system (CNS) cryptococcosis (CNSc) has emerged as a major opportunistic infection in the immunocompromised population of India. We have analyzed the clinical features of CNSc and epidemiology of Cryptococcus neoformans and Cryptococcus gattii. A total of 160 clinical isolates of C. neoformans/gattii recovered ... Read more >>

Med. Mycol. (Medical mycology)
[2019, :]

Cited: 0 times

View full text PDF listing >>



The Role of Brain Derived Neurotrophic Factor in HIV-Associated Neurocognitive Disorder: From the Bench-Top to the Bedside.

Henry Michael, Thabisile Mpofana, Suvira Ramlall, Frasia Oosthuizen,

Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) remains prevalent in the anti-retroviral (ART) era. While there is a complex interplay of many factors in the neuropathogenesis of HAND, decreased neurotrophic synthesis has been shown to contribute to synaptic degeneration which is a hallmark of HAND neuropathology. Brain derived neurotrophic factor ... Read more >>

Neuropsychiatr Dis Treat (Neuropsychiatric Disease and Treatment)
[2020, 16:355-367]

Cited: 0 times

View full text PDF listing >>



Fulminant Acanthamoeba castellanii Encephalitis in an Ibrutinib-Treated Patient.

Jessica W Crothers, Liangge Hsu, Francisco M Marty,

We report a case of fulminant Acanthamoeba castellanii encephalitis in a patient with chronic lymphocytic leukemia treated with ibrutinib. The unusually rapid neurologic decline and fatal outcome observed are probably related to alterations in immunologic function associated with inhibition of Bruton tyrosine kinase. ... Read more >>

Open Forum Infect Dis (Open Forum Infectious Diseases)
[2020, 7(2):ofaa025]

Cited: 0 times

View full text PDF listing >>



Neurological worsening during treatment of an immunocompetent adult with Cryptococcus neoformans meningitis.

Singhal Tanu, Munshi Mihir, Soman Rajeev, Aggarwal Annu,

Cryptococcal meningitis is being increasingly described in immunocompetent adults. We describe here a young immuncompetent adult of Indian origin from Ghana, West Africa with cryptococcal meningitis who had several ups and downs during his treatment. First he developed neurologic worsening due to premature transition from intensive to consolidation phase therapy. ... Read more >>

Med Mycol Case Rep (Medical mycology case reports)
[2020, 27:48-51]

Cited: 0 times

View full text PDF listing >>



Pulmonary Cryptococcus infections as a manifestation of idiopathic CD4 lymphocytopenia: case report and literature review.

Christina S Thornton, Oscar Larios, Jennifer Grossman, Thomas P Griener, Steven Vaughan,

BACKGROUND:Idiopathic CD4 lymphocytopenia (ICL) is a rare clinical disease with relative CD4 deficiency in the absence of HIV infection. The pathogenicity of ICL is poorly understood with an unclear incidence rate in the general population. Sequelae of ICL includes AIDS-defining infections, which most commonly includes Cryptococcus neoformans. Typically, C. neoformans ... Read more >>

BMC Infect. Dis. (BMC infectious diseases)
[2019, 19(1):862]

Cited: 0 times

View full text PDF listing >>



Advertisement

Disclaimer
2.2554 s