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[MORAXELLA OSLOENSIS BACTEREMIA WITH PNEUMONIA: FIRST REPORTED CASE IN ISRAEL].

Valeriy Bilyk, Othman Ali, Ahmad Moghrabi,

INTRODUCTION:Community acquired pneumonia (CAP), an acute infection of the pulmonary parenchyma acquired in the community, is generally treated in an outpatient setting and involves different etiological agents. In the adult community, the most common pathogen in the disease is Streptococcus pneumonia, though other multiple etiological agents (atypical) have been involved, ... Read more >>

Harefuah (Harefuah)
[2020, 159(3):163-165]

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Regret among primary care physicians: a survey of diagnostic decisions.

Beate S Müller, Norbert Donner-Banzhoff, Martin Beyer, Jörg Haasenritter, Angelina Müller, Carola Seifart,

BACKGROUND:Experienced and anticipated regret influence physicians' decision-making. In medicine, diagnostic decisions and diagnostic errors can have a severe impact on both patients and physicians. Little empirical research exists on regret experienced by physicians when they make diagnostic decisions in primary care that later prove inappropriate or incorrect. The aim of ... Read more >>

BMC Fam Pract (BMC family practice)
[2020, 21(1):53]

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Antimicrobial prescriptions and adherence to prudent use guidelines for selected canine diseases in Switzerland in 2016.

Bérénice Lutz, Claudia Lehner, Kira Schmitt, Barbara Willi, Gertraud Schüpbach, Meike Mevissen, Ruth Peter, Cedric Müntener, Hanspeter Naegeli, Simone Schuller,

Background:Antimicrobial resistance is an increasing problem in human and veterinary medicine and is closely linked to the use of antimicrobials. The objective of this study was to describe antimicrobial prescriptions for selected canine diseases in Switzerland during 2016. Methods:Dogs presented to two university hospitals and 14 private practices for acute ... Read more >>

Vet Rec Open (Veterinary Record Open)
[2020, 7(1):e000370]

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E-Cigarette, or Vaping, Product Use Associated Lung Injury (EVALI) with Acute Respiratory Failure in Three Adolescent Patients: a Clinical Timeline, Treatment, and Product Analysis.

Ramya Billa, Cody Tigges, Niranjan Vijayakumar, Joshua Radke, Caitlin Pedati, Rebecca Weiner, Daniel McCabe,

IntroductionE-cigarette, or vaping, product use associated lung injury (EVALI) has become a recent concern among public health officials. Factors that contribute to the concern include an increasing number of cases over time, the severity of the illness, and an unknown understanding of the pathophysiology and etiology of the illness.Case SeriesWe ... Read more >>

J Med Toxicol (Journal of Medical Toxicology)
[0, :1-7]

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Procalcitonin: A promising tool or just another overhyped test?

Robin Paudel, Prerna Dogra, Ashley A Montgomery-Yates, Angel Coz Yataco,

Sepsis is the leading cause of death worldwide. Timely administration of antibiotics is recognized as the cornerstone in the management of sepsis. However, inappropriate use of antibiotics may lead to adverse effects and the selection of drug-resistant pathogens. Microbiological cultures remain the gold standard to diagnose infection despite their low ... Read more >>

Int J Med Sci (International journal of medical sciences)
[2020, 17(3):332-337]

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Assessment of Bronchiectasis in HIV Patients among an Urban Population.

Veena Dronamraju, Navneet Singh, Justin Poon, Sachi Shah, Joseph Gorga, Hector Ojeda-Martinez, Samy McFarlane,

Bronchiectasis is characterized by permanent destruction of the airways that presents with productive cough, as well as bronchial wall thickening and luminal dilatation on computed tomographic (CT) scan of the chest; it is associated with high mortality. Accumulating data suggests higher rates of bronchiectasis among the HIV-positive population. This case ... Read more >>

Case Rep Pulmonol (Case reports in pulmonology)
[2020, 2020:8903809]

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Risk factors of invasive candidiasis in critical cancer patients after various gastrointestinal surgeries: A 4-year retrospective study.

Rui Xia, Donghao Wang,

For early diagnosis and treatment of invasive candidiasis (IC), the well-known risk factors may not apply in the intensive care unit (ICU). This retrospective study identified the risk factors predicting IC and candidemia in cancer patients under intensive care after gastrointestinal surgery.Enrolled were 229 cancer patients admitted to our oncology ... Read more >>

Medicine (Baltimore) (Medicine)
[2019, 98(44):e17704]

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Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV Cidofovir.

Joseph Zhao, Ashton Yap, Eric Wu, Chian Yong Low, Jane Yap,

Adenovirus is a common cause of acute febrile respiratory infection in children and are generally self-limiting although pneumonia can occur in neonates and adults with compromised immunity. However, severe adenovirus pneumonia in healthy adults has been rarely described. Here, we report a case of severe community-acquired adenovirus pneumonia in a ... Read more >>

Respir Med Case Rep (Respiratory medicine case reports)
[2020, 30:101037]

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Inhaled Corticosteroids and Placebo Treatment Effects in Adult Patients With Cough: A Systematic Review and Meta-analysis.

Seung Eun Lee, Ji Hyang Lee, Hyun Jung Kim, Byung Jae Lee, Sang Heon Cho, David Price, Alyn H Morice, Woo Jung Song,

PURPOSE:Inhaled corticosteroids (ICSs) are often considered an empirical therapy in the management of patients with cough. However, ICS responsiveness is difficult to interpret in daily clinical practice, as the improvements may include placebo effects or self-remission. We aimed to evaluate ICS and placebo treatment effects in adult patients with cough. ... Read more >>

Allergy Asthma Immunol Res (Allergy, asthma & immunology research)
[2019, 11(6):856-870]

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Clinical manifestations and outcome analysis of invasive pulmonary aspergillosis infection: a retrospective study in 43 nonneutropenic patients.

Lihong Zhang, Chunli Che,

J. Int. Med. Res. (The Journal of international medical research)
[2019, 47(11):5680-5688]

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Rickettsia typhi infection presenting as severe ARDS.

Liem T Tran, Jessica L Helms, Miguel Sierra-Hoffman, Mark L Stevens, Rafael Deliz-Aguirre, Mirams T Castro-Lainez, Rafael J Deliz,

Murine typhus, also known as endemic typhus, is a disease resulting from an infection caused by the gram-negative bacillus Rickettsia typhi. Murine typhus is identified worldwide, predominantly in tropical and subtropical geographic locations. Transmission occurs through direct inoculation by an arthropod vector, most commonly the rat flea, Xenopsylla cheopis. rickettsial ... Read more >>

IDCases (IDCases)
[2019, 18:e00645]

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HTLV-1c associated bronchiolitis in an Aboriginal man from central Australia.

Fabian Chiong, Hubertus Jersmann, Kim Wilson, Lloyd Einsiedel,

We describe the first case of HTLV associated bronchiolitis to be associated with HTLV-1c subtype infection. An Aboriginal man with HTLV-1 infection was repeatedly admitted to Alice Springs Hospital, central Australia, with hypercapnic respiratory failure from the age of 28 years. High resolution CT chest findings were consistent with bronchiolitis ... Read more >>

IDCases (IDCases)
[2020, 19:e00714]

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BundlED Up: A Narrative Review of Antimicrobial Stewardship Initiatives and Bundles in the Emergency Department.

Maressa Santarossa, Emily N Kilber, Eric Wenzler, Fritzie S Albarillo, Ethan J Sterk,

Antimicrobial stewardship (ASP) is becoming an increasingly high priority worldwide, yet the emergency department (ED) is an area where stewardship is often neglected. Implementing care bundles, guidelines, and protocols appears to be a rational strategy for ED stewardship given the inherently dynamic and hectic environment of care. Multiple questions still ... Read more >>

Pharmacy (Basel) (Pharmacy (Basel, Switzerland))
[2019, 7(4):]

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Antimicrobial Resistance in the Asia Pacific region: a meeting report.

Esabelle Lo Yan Yam, Li Yang Hsu, Eric Peng-Huat Yap, Tsin Wen Yeo, Vernon Lee, Joergen Schlundt, May O Lwin, Direk Limmathurotsakul, Mark Jit, Peter Dedon, Paul Turner, Annelies Wilder-Smith,

The Asia Pacific region, home to two-thirds of the world's population and ten of the least developed countries, is considered a regional hot-spot for the emergence and spread of antimicrobial resistance (AMR). Despite this, there is a dearth of high-quality regional data on the extent of AMR. Recognising the urgency ... Read more >>

Antimicrob Resist Infect Control (Antimicrobial resistance and infection control)
[2019, 8:202]

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Chronic Cough in Adults: Make the Diagnosis and Make a Difference.

Alan G Kaplan,

Chronic cough is common and impactful, frustrating both patients and clinicians. An empirical trial of therapy is often done with inhaled corticosteroids, but this practice should be replaced with attempting to make an accurate diagnosis. The three most common causes are upper airway cough syndrome, asthma, and gastroesophageal reflux disease ... Read more >>

Pulm Ther (Pulmonary therapy)
[2019, 5(1):11-21]

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Mycoplasma pneumoniae detection in children with respiratory tract infections and influence on management - a retrospective cohort study in Switzerland.

Alexa Dierig, Hans Hellmuth Hirsch, Marie-Luise Decker, Julia Anna Bielicki, Ulrich Heininger, Nicole Ritz,

AIM:To evaluate the frequency of Mycoplasma pneumoniae in nasopharyngeal specimens from children with respiratory tract infections (RTIs) and to detail clinical characteristics and management. METHODS:The study was designed as a retrospective cohort study. All children with RTI and nucleic acid amplification testing from nasopharyngeal specimens were analysed. Clinical data were ... Read more >>

Acta Paediatr. (Acta paediatrica (Oslo, Norway : 1992))
[2020, 109(2):375-380]

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Reflux characteristics in patients with gastroesophageal reflux-related chronic cough complicated by laryngopharyngeal reflux.

Yiming Yu, Siwan Wen, Shengyuan Wang, Cuiqin Shi, Hongmei Ding, Zhongmin Qiu, Xianghuai Xu, Li Yu,

Background:This study aimed to investigate the reflux characteristics in patients with gastroesophageal reflux-related chronic cough (GERC) complicated by laryngopharyngeal reflux (LPR). Methods:Patients with chronic cough were recruited. Reflux symptom index (RSI) scoring, cough symptom scoring, assessment of capsaicin cough sensitivity, and multichannel intraluminal impedance and pH monitoring (MII-pH) were performed. ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(20):529]

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First Reported Case of Candida dubliniensis Endocarditis Related to Implantable Cardioverter-Defibrillator.

Nooraldin Merza, John Lung, Taryn B Bainum, Assad Mohammedzein, Shanna James, Mazin Saadaldin, Tarek Naguib,

A 36-year-old male presented to the ED with acute chronic hyponatremia found on routine weekly lab work with one-week history of generalized weakness, confusion, nausea/vomiting, and diarrhea. The patient has nonischemic cardiomyopathy of unknown etiology diagnosed in his teens with an AICD device placed 8 years ago and receiving milrinone ... Read more >>

Case Rep Cardiol (Case reports in cardiology)
[2020, 2020:6032873]

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Is Meropenem as a Monotherapy Truly Incompetent for Meropenem-Nonsusceptible Bacterial Strains? A Pharmacokinetic/Pharmacodynamic Modeling With Monte Carlo Simulation.

Xiangqing Song, Yi Wu, Lizhi Cao, Dunwu Yao, Minghui Long,

Infections due to meropenem-nonsusceptible bacterial strains (MNBSs) with meropenem minimum inhibitory concentrations (MICs) ≥ 16 mg/L have become an urgent problem. Currently, the optimal treatment strategy for these cases remains uncertain due to some limitations of currently available mono- and combination therapy regimens. Meropenem monotherapy using a high dose of ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2019, 10:2777]

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Influence of the Lung Microbiota Dysbiosis in Chronic Obstructive Pulmonary Disease Exacerbations: The Controversial Use of Corticosteroid and Antibiotic Treatments and the Role of Eosinophils as a Disease Marker.

Domenico Maurizio Toraldo, Luana Conte,

Chronic obstructive pulmonary disease (COPD) is a debilitating lung disease associated with loss of lung function, poorer quality of life, co-morbidities, significant mortality, and higher health care costs. Frequent acute exacerbations of COPD are sudden worsening of symptoms, the nature of which is associated with bacterial or viral infections. However, ... Read more >>

J Clin Med Res (Journal of clinical medicine research)
[2019, 11(10):667-675]

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A hidden face of migration: Diabetic ketoacidosis in a severely malnourished refugee.

Suzanne Sap, Yanelle Wandji Nzebia, Viola Dohvoma Andin, Paule Yvette Hagbe, Ritha Mbono, Irene Fotang Tangmoh, Paul Olivier Koki,

Besides violence, the risk of under nutrition and infection, migrant children with noncommunicable chronic diseases face serious challenges in the management of their conditions. Management of diabetic ketoacidosis in a severely malnourished patient includes careful hydration, therapeutic feeding, and monitoring. ... Read more >>

Clin Case Rep (Clinical case reports)
[2019, 7(12):2425-2428]

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Comparison of drug safety data obtained from the monitoring system, literature, and social media: An empirical proof from a Chinese patent medicine.

Ruixue Hu, Su Golder, Guoyan Yang, Xun Li, Di Wang, Liqiong Wang, Ruyu Xia, Nanqi Zhao, Sainan Fang, Baoyong Lai, Jianping Liu, Yutong Fei,

OBJECTIVES:To investigate the consistency of adverse events (AEs) and adverse drug reactions (ADRs) reported in the literature, monitoring and social media data. METHODS:Using one Chinese patent medicine-Cordyceps sinensis extracts (CSE) as an example, we obtained safety data from the national monitoring system (July 2002 to February 2016), literature (up to ... Read more >>

PLoS ONE (PloS one)
[2019, 14(11):e0222077]

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Life-Threatening Infectious Complications in Sickle Cell Disease: A Concise Narrative Review.

Dominik Ochocinski, Mansi Dalal, L Vandy Black, Silvana Carr, Judy Lew, Kevin Sullivan, Niranjan Kissoon,

Sickle cell disease (SCD) results in chronic hemolytic anemia, recurrent vascular occlusion, insidious vital organ deterioration, early mortality, and diminished quality of life. Life-threatening acute physiologic crises may occur on a background of progressive diminishing vital organ function. Sickle hemoglobin polymerizes in the deoxygenated state, resulting in erythrocyte membrane deformation, ... Read more >>

Front Pediatr (Frontiers in pediatrics)
[2020, 8:38]

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Bioactive Molecules and Their Mechanisms of Action.

Dongdong Wang, Elke Heiss, Karel Šmejkal, Atanas G Atanasov,

Chronic inflammation with a wide spectrum of connected diseases (e [...]. ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2019, 24(20):]

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Short-term insomnia and common cold: A cross-sectional study.

Simmon Gomi,

Background:The role of insomnia as a symptom of cold has not been fully explored. This study aimed to identify the nature of mild short-term insomnia (MSTI) as a symptom in common cold and examine the relationship between the diagnosis of common cold and MSTI. Methods:A cross-sectional study was conducted at ... Read more >>

J Gen Fam Med (Journal of general and family medicine)
[2019, 20(6):244-250]

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