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Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration.

Francisco Bosch-Morell, Victoria Villagrasa, Teresa Ortega, Nuria Acero, Dolores Muñoz-Mingarro, M Eugenia González-Rosende, Encarna Castillo, M Amparo Sanahuja, Pilar Soriano, Isabel Martínez-Solís,

The retina may suffer neurodegenerative damages, as other tissues of the central nervous system do, and serious eye diseases may develop. One of them is age-related macular degeneration, which causes progressive loss of vision due to retina degeneration. Treatment of age-related macular degeneration focuses on antioxidant agents and anti-vascular endothelial ... Read more >>

Neural Regen Res (Neural regeneration research)
[2020, 15(12):2207-2216]

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Food frequency questionnaire assessing traditional food consumption in Dene/Métis communities, Northwest Territories, Canada.

Mylène Ratelle, Kelly Skinner, Sara Packull-McCormick, Brian Laird,

Food Frequency Questionnaires (FFQ) can be used to document food consumption and to estimate the intake of contaminants for Indigenous populations. The objective of this project was to refine and implement an FFQ to estimate the consumption of traditional locally harvested foods for Dene/Métis in the Northwest Territories, Canada. The ... Read more >>

Int J Circumpolar Health (International journal of circumpolar health)
[2020, 79(1):1760071]

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Blueberry extract as a potential pharmacological tool for preventing depressive-like behavior and neurochemical dysfunctions in mice exposed to lipopolysaccharide.

Luiza Spohr, Karina Pereira Luduvico, Mayara Sandrielly Pereira Soares, Natália Pontes Bona, Pathise Souto Oliveira, Julia Eisenhardt de Mello, Fernando Lopez Alvez, Fernanda Cardoso Teixeira, Anelize de Oliveira Campello Felix, Francieli Moro Stefanello, Roselia Maria Spanevello,

OBJECTIVE:Major depressive disorder is a debilitating and recurrent psychiatric disorder. Blueberries have several biological properties, including neuroprotective effects, through antioxidant and anti-inflammatory actions. The aim of this study was to evaluate the effect of blueberry extract on depressive-like behavior and lipopolysaccharide (LPS)-induced neurochemical changes. METHODS:Mice were pretreated with vehicle, fluoxetine ... Read more >>

Nutr Neurosci (Nutritional neuroscience)
[2020, :1-14]

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An 8-Week Freeze-Dried Blueberry Supplement Impacts Immune-Related Pathways: A Randomized, Double-Blind Placebo-Controlled Trial

Michèle Rousseau, Justine Horne, Frédéric Guénard, Juan de Toro-Martín, Véronique Garneau, Valérie Guay, Michèle Kearney, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie-Claude Vohl,

Abstract Background: Blueberries contain high level of polyphenolic compounds with high in vitro antioxidant capacities. Their consumption has been associated with improved vascular and metabolic health. Purpose: The objective was to examine the effects of blueberry supplement consumption on metabolic syndrome (MetS) parameters and potential underlying mechanisms of action. Methods: ... Read more >>

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Validation of a decision-support system for blueberry anthracnose and fungicide sensitivity of Colletotrichum gloeosporioides isolates.

Andre B Gama, Leandro Gabriel Cordova, Carolina Suguinoshita Rebello, Natalia A Peres,

Blueberry is an increasingly important crop in Florida. Anthracnose fruit rot (AFR), mostly caused by Colletotrichum gloeosporioides, is favored by long wetness periods and temperatures from 15 to 27oC. Currently, the model in the Strawberry Advisory System (StAS) guides fungicide applications targeting strawberry AFR. Given the similarity between blueberry and ... Read more >>

Plant Dis. (Plant disease)
[2020, :]

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Comparison and Interpretation of Characteristics of Rhizosphere Microbial Communities in Three Blueberry Varieties: The Benefits to Blueberry Production

Yan Zhang, Wei Wang, Zhangjun Shen, Jingjing Wang, Yajun Chen, Dong Wang, Gang Liu, Maozhen Han,

Abstract Background: Rhizosphere microbiota play a critical role in biogeochemical cycles and carry out various vital functions in plant production. Studies on the rhizosphere microbiome of various plants proved that rhizosphere microbiota can regulate the growth and improve the yield of plants. However, the rhizosphere microbiome of commercial blueberry remains ... Read more >>

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Adjusting Mineral Nutrition of Lowbush Blueberry to Agroecosystem Conditions

Serge-Étienne Parent, Jean Lafond, Maxime Paré, Léon Etienne Parent, Noura ZIadi,

Nutrient management of lowbush blueberry (Vaccinium angustifolium Ait.) depends on several yield-limiting features. Machine learning models can process such yield-impacting variables to predict berry yield. We investigated the effects of local variables on yields and nutrient management of lowbush blueberry. We collected 1504 observations from N-P-K fertilizer trials conducted in ... Read more >>

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Gelatin-based coating enriched with blueberry juice preserves the nutraceutical quality and reduces the microbial contamination of tomato fruit.

Stefania Frassinetti, Antonella Castagna, Marco Santin, Luisa Pozzo, Irene Baratto, Vincenzo Longo, Annamaria Ranieri,

To preserve quality and extend the shelf life of tomato, a bioactive edible coating was prepared using gelatin wastes from pharmaceutical industry and lyophilised blueberry juice (BJ). The effectiveness of gelatin-coating (G) and G enriched with blueberry juice (GB) was tested, monitoring carotenoids, polyphenols and flavonoids content, the antioxidant activity ... Read more >>

Nat. Prod. Res. (Natural product research)
[2020, :1-5]

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Performing Parentage Analysis for Polysomic Inheritances Based on Allelic Phenotypes

Kang Huang, Gwendolyn Huber, Kermit Ritland, Derek Dunn, Baoguo Li,

Abstract Polyploidy poses several problems for parentage analysis. We present a new polysomic inheritance model for parentage analysis based on genotypes or allelic phenotypes to solve these problems. The effects of five factors are simultaneously accommodated in this model: (i) double-reduction, (ii) null alleles, (iii) negative amplification, (iv) genotyping errors ... Read more >>

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The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties.

Bianca-Eugenia Ștefănescu, Lavinia Florina Călinoiu, Floricuța Ranga, Florinela Fetea, Andrei Mocan, Dan Cristian Vodnar, Gianina Crișan,

Blueberries have seen an ascending production line boosted by World Health Organization (WHO) approvals for their contributions to a healthy diet and the evidence that they act against different diseases. This increase resulted in significant amounts of discarded leaves, which could be a valuable source of bioactive compounds. In the ... Read more >>

Plants (Basel) (Plants (Basel, Switzerland))
[2020, 9(9):]

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Whole Blueberry and Isolated Polyphenol-Rich Fractions Modulate Specific Gut Microbes in an In Vitro Colon Model and in a Pilot Study in Human Consumers.

Alexandra Ntemiri, Tarini S Ghosh, Molly E Gheller, Tam T T Tran, Jamie E Blum, Paola Pellanda, Klara Vlckova, Marta C Neto, Amy Howell, Anna Thalacker-Mercer, Paul W O'Toole,

Blueberry (BB) consumption is linked to improved health. The bioconversion of the polyphenolic content of BB by fermentative bacteria in the large intestine may be a necessary step for the health benefits attributed to BB consumption. The identification of specific gut microbiota taxa that respond to BB consumption and that ... Read more >>

Nutrients (Nutrients)
[2020, 12(9):]

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Changes of the Aroma Composition and Other Quality Traits of Blueberry 'Garden Blue' during the Cold Storage and Subsequent Shelf Life.

Xiaoxue Yan, Jun Yan, Siyi Pan, Fang Yuan,

The changes of volatile composition and other quality traits of blueberry during postharvest storage were investigated. Blueberries were packaged in vented clam-shell containers, and stored at 0 °C for 0, 15 and 60 days, followed by storage at room temperature (25 °C) for up to 8 days for quality evaluation. ... Read more >>

Foods (Foods (Basel, Switzerland))
[2020, 9(9):]

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Genomic insight into the developmental history of southern highbush blueberry populations.

Soichiro Nishiyama, Mao Fujikawa, Hisayo Yamane, Kenta Shirasawa, Ebrahiem Babiker, Ryutaro Tao,

Interspecific hybridization is a common breeding approach for introducing novel traits and genetic diversity to breeding populations. Southern highbush blueberry (SHB) is a blueberry cultivar group that has been intensively bred over the last 60 years. Specifically, it was developed by multiple interspecific crosses between northern highbush blueberry [NHB, Vaccinium ... Read more >>

Heredity (Edinb) (Heredity)
[2020, :]

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Phenolics profiling by HPLC-DAD-ESI-MSn aided by principal component analysis to classify Rabbiteye and Highbush blueberries.

Paula Becker Pertuzatti, Milene Teixeira Barcia, Sérgio Gómez-Alonso, Helena Teixeira Godoy, Isidro Hermosin-Gutierrez,

Although blueberries are widely studied, little information exists on their composition and content of flavonol glycosides. Most studies identify only a few flavonols in blueberries due to separation and identification issues. In the present study, we identified 44 flavonols and chlorogenic acid in 30 samples of Highbush and Rabbiteye blueberry, ... Read more >>

Food Chem (Food chemistry)
[2020, 340:127958]

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Repellent, oviposition-deterrent, and insecticidal activity of the fungal pathogen Colletotrichum fioriniae on Drosophila suzukii (Diptera: Drosophilidae) in highbush blueberries.

Pablo Urbaneja-Bernat, Timothy Waller, Cesar Rodriguez-Saona,

Spotted-wing drosophila, Drosophila suzukii, and the anthracnose pathogen Colletotrichum fioriniae are an important insect pest and fungal disease of highbush blueberries, respectively, in the United States. However, whether C. fioriniae infection affects D. suzukii preference and performance remains unknown. Here, we conducted choice and no-choice studies to determine the repellent, ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):14467]

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An Anthocyanin-Enriched Extract from Vaccinium uliginosum Improves Signs of Skin Aging in UVB-Induced Photodamage.

Kyungae Jo, Gi Yeon Bae, Kyoungwon Cho, Sung Sun Park, Hyung Joo Suh, Ki-Bae Hong,

Accumulating evidence indicates that botanical extracts affect skin biophysical parameters, such as hydration, transepidermal water loss (TEWL), melanin index, erythema index, and wrinkle development. Vaccinium uliginosum extract contains a high level of anthocyanins as antioxidant and is ideal for use in dietary skin care products. Here, we assessed the photoprotective ... Read more >>

Antioxidants (Basel) (Antioxidants (Basel, Switzerland))
[2020, 9(9):]

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Characterization of Andean Blueberry in Bioactive Compounds, Evaluation of Biological Properties and in vitro Bioaccessibility

Nieves Baenas, Jenny Ruales, Diego Moreno, Daniel Alejandro Barrio, Carla Stinco, Gabriela Martínez-Cifuentes, Antonio Meléndez-Martínez, Almudena García-Ruiz,

Andean blueberries are wild berries grown and consumed in Ecuador which contain high values of bioactive compounds, mainly anthocyanins, with powerful antioxidant activity. The aim of this study was to evaluate the profile and contents of (poly)phenols and carotenoids in Andean blueberry by HPLC-DAD-MSn and determine a wide range of ... Read more >>

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Metabolomic Selection for Enhanced Fruit Flavor

Vincent Colantonio, Luis Felipe Ferrão, Denise Tieman, Nikolay Bliznyuk, Charles Sims, Harry Klee, Patricio Munoz, Marcio Resende,

Abstract Although they are staple foods in cuisines globally, commercial fruit varieties have become progressively less flavorful over time. Due to the cost and difficulty associated with flavor phenotyping, many breeding programs have long been challenged in selecting for this complex trait. To address this issue, we leveraged targeted metabolomics ... Read more >>

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Highbush blueberry proanthocyanidins alleviate Porphyromonas gingivalis-induced deleterious effects on oral mucosal cells.

Amel Ben Lagha, Amy Howell, Daniel Grenier,

Strong evidence points to Porphyromonas gingivalis, a Gram-negative anaerobic bacterium, as a keystone species in the development of the chronic form of periodontitis. The aim of the present study was to investigate the ability of highbush blueberry proanthocyanidins (PACs) to alleviate the P. gingivalis-induced deleterious effects on oral mucosal cells. We ... Read more >>

Anaerobe (Anaerobe)
[2020, 65:102266]

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Identification of Colletotrichum Species Associated with Blueberry Anthracnose in Sichuan, China.

Xuan Liu, Xiaojuan Zheng, Muhammad Ibrahim Khaskheli, Xiaofang Sun, Xiaoli Chang, Guoshu Gong,

Anthracnose caused by Colletotrichum spp. is an important disease of blueberries and results in large economic losses for blueberry growers. Samples of anthracnose were collected from six main blueberry cultivation areas in Sichuan Province. In total, 74 Colletotrichum isolates were obtained through a single-spore purification method and identified to the ... Read more >>

Pathogens (Pathogens (Basel, Switzerland))
[2020, 9(9):]

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Consumption of a Blueberry-Enriched Diet by Women for 6 Weeks Alters Determinants of Human Muscle Progenitor Cell Function.

Jamie E Blum, Brandon J Gheller, Sinwoo Hwang, Erica Bender, Mary Gheller, Anna E Thalacker-Mercer,

BACKGROUND:Human muscle progenitor cell (hMPC) function facilitates skeletal muscle regeneration and is influenced by circulating factors. Yet it is unknown whether dietary interventions impact hMPC function. Blueberry consumption was examined due to the pro-proliferative and antioxidant effects of blueberries and blueberry-derived compounds. OBJECTIVES:This study measured indicators of hMPC function in ... Read more >>

J. Nutr. (The Journal of nutrition)
[2020, 150(9):2412-2418]

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Intelligent pH indicator films containing anthocyanins extracted from blueberry peel for monitoring tilapia fillet freshness.

Ce Shi, Jiaran Zhang, Zhixin Jia, Xinting Yang, Zhongyun Zhou,

BACKGROUND:Fish spoilage leads to an increase in the pH value of the fish. A colorimetric pH indicator can be used to monitor fish spoilage and has been exploited in intelligent packaging because of its simplicity, practicality and low cost. The aim of this study was to develop two pH-indicator films ... Read more >>

J. Sci. Food Agric. (Journal of the science of food and agriculture)
[2020, :]

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Determining the Effect of Postharvest Cold Storage Treatment on the Survival of Immature Drosophila suzukii (Diptera: Drosophilidae) in Small Fruits.

Laura J Kraft, D Adeline Yeh, Miguel I Gómez, Hannah J Burrack,

We evaluated the effect of postharvest cold storage temperature (0.0-2.2°C) and duration (3-5 d) on pupal emergence of single life stage populations of laboratory-generated Drosophila suzukii (Matsumura) and mixed-age populations collected in the field from blackberries, blueberries, strawberries, and raspberries. For field-infested fruit, cold storage at any temperature and duration ... Read more >>

J. Econ. Entomol. (Journal of economic entomology)
[2020, :]

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Plant guttation provides nutrient-rich food for insects.

Pablo Urbaneja-Bernat, Alejandro Tena, Joel González-Cabrera, Cesar Rodriguez-Saona,

Plant guttation is a fluid from xylem and phloem sap secreted at the margins of leaves from many plant species. All previous studies have considered guttation as a water source for insects. Here, we hypothesized that plant guttation serves as a reliable and nutrient-rich food source for insects with effects ... Read more >>

Proc. Biol. Sci. (Proceedings. Biological sciences)
[2020, 287(1935):20201080]

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Vaccinium myrtillus L. extract and its native polyphenol-recombined mixture have anti-proliferative and pro-apoptotic effects on human prostate cancer cell lines.

Massimo Del Bubba, Claudia Di Serio, Lapo Renai, Cristina Vanessa Agata Scordo, Leonardo Checchini, Andrea Ungar, Francesca Tarantini, Riccardo Bartoletti,

Vaccinium myrtillus berry extract (VME) and a recombined standard mixture (RSM) of its main native phenolic compounds were investigated for cell growth inhibition and pro-apoptotic activity on hormone-dependent (LNCaP) and hormone-independent (PC3 and DU-145) prostate cancer (PCa) cell lines. Normal prostate epithelial cells (PrEC) were also studied in comparison. VME ... Read more >>

Phytother Res (Phytotherapy research : PTR)
[2020, :]

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