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Bicuspid Aortic Valve

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Serial evaluation of cardiac biomarker NT-proBNP with speckle tracking echocardiography in a 6-year-old Golden Retriever dog with subaortic stenosis and dilated cardiomyopathy.

Woong-Bin Ro, Min-Hee Kang, Hee-Myung Park,

Vet Q (The veterinary quarterly)
[2020, 40(1):77-82]

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Management of Late-Presenting Congenital Combined Heart Defect - Bicuspid Aortic Valve and Ventricular Septal Aneurysm.

Violeta V Groudeva, Borislav G Atzev, Dimitar G Petkov,

BACKGROUND Bicuspid aortic valve is the most common congenital heart malformation, encountered in 1-2% of the population, while interventricular septal defect and patent ductus arteriosus are the most common congenital malformations associated with bicuspid aortic valve. Although bicuspid valve can have no clinical manifestation, patients with bicuspid valve are prone ... Read more >>

Am J Case Rep (The American journal of case reports)
[2020, 21:e919766]

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6q25.1 (TAB2) microdeletion is a risk factor for hypoplastic left heart: a case report that expands the phenotype.

Andrew Cheng, Whitney Neufeld-Kaiser, Peter H Byers, Yajuan J Liu,

INTRODUCTION:Hypoplastic left heart syndrome (HLHS) is a rare but devastating congenital heart defect (CHD) accounting for 25% of all infant deaths due to a CHD. The etiology of HLHS remains elusive, but there is increasing evidence to support a genetic cause for HLHS; in particular, this syndrome is associated with ... Read more >>

BMC Cardiovasc Disord (BMC cardiovascular disorders)
[2020, 20(1):137]

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Prevalence of permanent pacemaker implantation after conventional aortic valve replacement-a propensity-matched analysis in patients with a bicuspid or tricuspid aortic valve: a benchmark for transcatheter aortic valve replacement.

Josephina Haunschild, Martin Misfeld, Thomas Schroeter, Frank Lindemann, Piroze Davierwala, Konstantin von Aspern, Ricardo A Spampinato, Stefan Weiss, Michael A Borger, Christian D Etz,

OBJECTIVES:Elective treatment of aortic valve disease by transcatheter aortic valve replacement (TAVR) is becoming increasingly popular, even in patients with low risk and intermediate risk. Even patients with a bicuspid aortic valve (BAV) are increasingly considered eligible for TAVR. Permanent pacemaker implantation (PMI) is a known-frequently understated-complication of TAVR affecting ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2020, :]

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Long-Term Risk Factors for Dilatation of the Proximal Aorta in a Large Cohort of Children With Bicuspid Aortic Valve.

Samuel Blais, Léamarie Meloche-Dumas, Anne Fournier, Frederic Dallaire, Nagib Dahdah,

BACKGROUND:Patients with bicuspid aortic valve (BAV) have a higher risk of developing aortic valve dysfunction and progressive proximal aorta dilatation, which can lead to aortic dissection. To this day, identification of children at risk of developing severe aortic dilatation during their pediatric follow-up is still challenging because most studies were ... Read more >>

Circ Cardiovasc Imaging (Circulation. Cardiovascular imaging)
[2020, 13(3):e009675]

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Distribution Patterns of Valvular and Vascular Complications in Bicuspid Aortic Valve.

Yongshi Wang, Boting Wu, Jun Li, Hongyu Liu, Xianhong Shu,

For its high occurrence and elevated risks for aortic valve dysfunction and vascular complications, bicuspid aortic valve (BAV) represents a great health challenge. However, the prevalence and clinical features of BAV in the Chinese population are inadequately illustrated.From January 2011 to December 2015, 3,673 BAV patients with 69.1% male predominance ... Read more >>

Int Heart J (International heart journal)
[2020, :]

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Predictors of Bicuspid Aortic Valve-Associated Aortopathy in Childhood: A Report From the MIBAVA Consortium.

Michael Grattan, Andrea Prince, Rawan Ruman, Conall Morgan, Michele Petrovic, Amanda Hauck, Luciana Young, Anders Franco-Cereceda, Bart Loeys, Salah A Mohamed, Harry Dietz, Seema Mital, Chun-Po Steve Fan, Cedric Manlhiot, Gregor Andelfinger, Luc Mertens,

BACKGROUND:Bicuspid aortic valve (BAV) is the most prevalent congenital heart defect affecting 1% to 2% of the population. It is associated with ascending aorta dilatation. Valve morphology, aortic stenosis (AS), and aortic insufficiency (AI) have been proposed as potential risk factors; however, evaluating their role is difficult, as these factors ... Read more >>

Circ Cardiovasc Imaging (Circulation. Cardiovascular imaging)
[2020, 13(3):e009717]

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Appropriateness of Transcatheter Aortic Valve Replacement: Insight From the OCEAN-TAVI Registry.

Taku Inohara, Sreekanth Vemulapalli, Shun Kohsaka, Fumiaki Yashima, Yusuke Watanabe, Shinichi Shirai, Norio Tada, Motoharu Araki, Toru Naganuma, Futoshi Yamanaka, Hiroshi Ueno, Minoru Tabata, Kazuki Mizutani, Akihiro Higashimori, Kensuke Takagi, Masanori Yamamoto, Hideyuki Shimizu, Keiichi Fukuda, Kentaro Hayashida, ,

Background Transcatheter aortic valve replacement (TAVR) is widely used; however, its appropriateness is unknown. We sought to investigate the appropriateness of TAVR. Methods and Results We assigned appropriateness ratings to patients undergoing TAVR for severe aortic stenosis between October 2013 and May 2017 at 14 Japanese hospitals participating in the ... Read more >>

Circ Cardiovasc Qual Outcomes (Circulation. Cardiovascular quality and outcomes)
[2020, :CIRCOUTCOMES119006146]

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Mid-term outcomes of valve-sparing root reimplantation with leaflet  repair.

Koki Yokawa, Soichiro Henmi, Hidekazu Nakai, Katsuhiro Yamanaka, Atsushi Omura, Takeshi Inoue, Yutaka Okita, Kenji Okada,

OBJECTIVES:Valve repair for aortic insufficiency (AI) requires a tailored surgical approach determined by the leaflet and aortic disease. In this study, we used a repair-oriented system for the classification of AI, and we elucidated long-term outcomes of aortic root reimplantation with this classification system. METHODS:From 1999 to 2018, a total ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2020, :]

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Impact of Valvular Heart Disease on Mortality, Thromboembolic and Cardiac Events in Japanese Patients With Atrial Fibrillation - The Fushimi AF Registry.

Kosuke Doi, Hisashi Ogawa, Kenjiro Ishigami, Syuhei Ikeda, Yuya Aono, Yasuhiro Hamatani, Akiko Fujino, Yoshimori An, Mitsuru Ishii, Moritake Iguchi, Nobutoyo Masunaga, Masahiro Esato, Hikari Tsuji, Hiromichi Wada, Koji Hasegawa, Mitsuru Abe, Masaharu Akao, ,

BACKGROUND:There is a growing burden of valvular heart disease (VHD) and atrial fibrillation (AF) due to population aging, but data regarding the characteristics and outcomes of patients with AF and concomitant VHD are lacking.Methods and Results:The Fushimi AF Registry is a community-based prospective survey of AF patients in Fushimi-ku, Kyoto. Among 3,566 ... Read more >>

Circ. J. (Circulation journal : official journal of the Japanese Circulation Society)
[2020, :]

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Current and Future Aspects of Multimodal Imaging, Diagnostic, and Treatment Strategies in Bicuspid Aortic Valve and Associated Aortopathies.

Shazia Afzal, Kerstin Piayda, Oliver Maier, Shouheng Goh, Katharina Hellhammer, Mareike Cramer, Florian Bönner, Amin Polzin, Niels Nijhof, Malte Kelm, Tobias Zeus, Verena Veulemans,

Bicuspid aortic valve (BAV) is the most frequent congenital cardiac abnormality leading to premature aortic valve apparatus dysfunction and is often associated with aortopathy. Therefore, current guidelines recommend a surgical aortic valve replacement (SAVR), even if many patients are deemed inoperable owing to their comorbidities and require alternatives such as ... Read more >>

J Clin Med (Journal of clinical medicine)
[2020, 9(3):]

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Outcomes of Transcatheter Aortic Valve Replacement in Patients with Bicuspid Aortic Valve Disease: A Report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.

Sharif A Halim, Fred H Edwards, David Dai, Zhuokai Li, Michael J Mack, David R Holmes, E Murat Tuzcu, Vinod H Thourani, J Kevin Harrison, J Matthew Brennan,

Background: Patients with bicuspid aortic valve (AV) stenosis were excluded from the pivotal evaluations of transcatheter AV replacement (TAVR) devices. We sought to evaluate the outcomes of TAVR in patients with bicuspid AV stenosis compared with those with tricuspid AV. Methods: We used data from the Society of Thoracic Surgeons ... Read more >>

Circulation (Circulation)
[2020, :]

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Aortic valve calcification in the era of non-coding RNAs: The revolution to come in aortic stenosis management?

Joseph Nader, Laurent Metzinger, Pierre Maitrias, Thierry Caus, Valérie Metzinger-Le Meuth,

Aortic valve stenosis remains the most frequent structural heart disease, especially in the elderly. During the last decade, we noticed an important consideration and a huge number of publications related to the medical and surgical treatment of this disease. However, the molecular aspect of this degenerative issue has also been ... Read more >>

Noncoding RNA Res (Non-coding RNA research)
[2020, 5(2):41-47]

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Dilatation of the Aorta in Bicuspid Aortic Valve Disease.

John M Simpson, Kuberan Pushparajah,

Circ Cardiovasc Imaging (Circulation. Cardiovascular imaging)
[2020, 13(3):e010448]

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Simplified Minimally Invasive Beating Heart Technique for Redo Isolated Tricuspid Valve Surgery

Chunsheng Wang, Shuyang Lu, Kai Song, Wangchao Yao, Limin Xia, Lili Dong, Yongxin Sun, Tao Hong, Shouguo Yang,

<title>Abstract</title> <p> <bold>Background</bold> Redo isolated tricuspid valve surgery has been associated with a high morbidity and mortality, and its optimal timing of surgical intervention remains controversial. Hence, we reviewed our early and midterm results with a simplified minimally invasive beating heart technique for isolated redo tricuspid valve surgery ... Read more >>

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To the research of treatments for the typical calcific disease of old aortic valve in the omics era: Is the miR-195 a therapeutic signature via targetable p38-MAPK/VWF axis in bicuspid aortic valve?

Carmela Rita Balistreri,

Int. J. Cardiol. (International journal of cardiology)
[2020, :]

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A Case of Trisomy 13 Mosaicism Presenting with a Severe Aortic Root Dilatation and Marfanoid Habitus due to an Unpredictable Cytogenetic Mechanism.

Pauline Monin, Nicolas Reynaud, Nadine Hanna, Sophie Dupuis-Girod, Marianne Till, Pauline Arnaud, Audrey Labalme, Eudeline Alix, Coline Poizat-Amar, Marie Faoucher, Lucie Ravella, Bernard Debost, Jean-François Obadia, Jean-Christophe Zech, Catherine Boileau, Damien Sanlaville, Patrick Edery, Audrey Putoux, Caroline Schluth-Bolard,

In this report, we present a new case of mosaic trisomy 13 with prolonged survival, firstly detected by array-CGH analysis which was carried out because of moderate intellectual disability with postaxial hexadactyly, dermatologic features, ventricular septal defect, bicuspid aortic valve, and aortic dystrophy in a 19-year-old male patient. In a ... Read more >>

Cytogenet. Genome Res. (Cytogenetic and genome research)
[2020, :]

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Percutaneous Repair of Ventricular Ruptures.

Rong Bing, Miles W.H. Behan, Renzo Pessotto, Nicholas L.M. Cruden, David B. Northridge,

Acquired ventricular wall ruptures can be life-threatening. Depending on the pathological features and anatomy, surgical repair can be technically… ... Read more >>

JACC Case Rep (Jacc. Case Reports)
[0, 2(3):341-346]

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Is myocardial revascularization really necessary in patients with ≥50% but <70% coronary stenosis undergoing valvular surgery?

Benedetto Del Forno, Guido Ascione, Elisabetta Lapenna, Cinzia Trumello, Stefania Ruggeri, Igor Belluschi, Alessandro Verzini, Giuseppe Iaci, David Ferrara, Davide Schiavi, Roberta Meneghin, Alessandro Castiglioni, Ottavio Alfieri, Michele De Bonis,

OBJECTIVES:The aim of this study is to evaluate the immediate and mid-term effects of omitting coronary artery bypass grafting in patients with moderate coronary artery stenosis who have a primary indication for valvular surgery. METHODS:We included 77 consecutive patients admitted to our Institution for aortic or mitral valve surgery between ... Read more >>

Eur J Cardiothorac Surg (European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery)
[2020, :]

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Stage B Aortic Regurgitation in Bicuspid Aortic Valve: New Observations on Progression Rate and Predictors.

Li-Tan Yang, Patricia A Pellikka, Maurice Enriquez-Sarano, Joseph F Maalouf, Christopher G Scott, Hector I Michelena,

JACC Cardiovasc Imaging (JACC. Cardiovascular imaging)
[2020, :]

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Totally endoscopic aortic valve replacement via an anterolateral approach using a standard prosthesis.

Masayoshi Tokoro, Sadanari Sawaki, Takahiro Ozeki, Mamoru Orii, Akihiko Usui, Toshiaki Ito,

OBJECTIVES:Totally endoscopic aortic valve replacement (AVR) is still a challenging operation, and only a few series reports exist in the literature. The purposes of this study were to establish a method for endoscopic AVR and evaluate its initial results. METHODS:A total of 47 patients (median age 76 years, 17 men) underwent ... Read more >>

Interact Cardiovasc Thorac Surg (Interactive cardiovascular and thoracic surgery)
[2020, 30(3):424-430]

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Outcomes of aortic coarctation surgical repair in adolescents and adults.

Sungkyu Cho, Chang-Ha Lee, Eung Re Kim, Jae Hong Lim,

OBJECTIVES:Coarctation of the aorta (CoA) in adolescents and adults is relatively rare. Several operative techniques have been reported, but there is no consensus. METHODS:From November 1994 to July 2018, a total of 24 adolescents and adults underwent CoA repair. The mean age at operation was 29.9 ± 15.1; 19 (79%) patients were ... Read more >>

Interact Cardiovasc Thorac Surg (Interactive cardiovascular and thoracic surgery)
[2020, :]

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Letter by Shar et al Regarding Article, "Low and Oscillatory Wall Shear Stress Is Not Related to Aortic Dilation in Patients With Bicuspid Aortic Valve: A Time-Resolved 3-Dimensional Phase-Contrast Magnetic Resonance Imaging Study".

Jason A Shar, Janet Liu, Samantha K Atkins, Philippe Sucosky,

Arterioscler. Thromb. Vasc. Biol. (Arteriosclerosis, thrombosis, and vascular biology)
[2020, 40(4):e114-e115]

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Response by Dux-Santoy et al to Letter Regarding Article, "Low and Oscillatory Wall Shear Stress Is Not Related to Aortic Dilation in Patients With Bicuspid Aortic Valve: A Time-Resolved 3-Dimensional Phase-Contrast Magnetic Resonance Imaging Study".

Lydia Dux-Santoy, Andrea Guala, Julio Sotelo, Sergio Uribe, Gisela Teixidó-Turà, Arturo Evangelista, José F Rodríguez-Palomares,

Arterioscler. Thromb. Vasc. Biol. (Arteriosclerosis, thrombosis, and vascular biology)
[2020, 40(4):e116-e117]

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Prosthetic aortic graft replacement of the ascending thoracic aorta alters biomechanics of the native descending aorta as assessed by transthoracic echocardiography.

Maria C Palumbo, Lisa Q Rong, Jiwon Kim, Pedram Navid, Razia Sultana, Jonathan Butcher, Alberto Redaelli, Mary J Roman, Richard B Devereux, Leonard N Girardi, Mario F L Gaudino, Jonathan W Weinsaft,

INTRODUCTION:In patients with ascending aortic (AA) aneurysms, prosthetic graft replacement yields benefit but risk for complications in the descending aorta persists. Longitudinal impact of AA grafts on native descending aortic physiology is poorly understood. METHODS:Transthoracic echocardiograms (echo) in patients undergoing AA elective surgical grafting were analyzed: Descending aortic deformation indices ... Read more >>

PLoS ONE (PloS one)
[2020, 15(3):e0230208]

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