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Post-treatment Lyme Disease as a Model for Persistent Symptoms in Lyme Disease.

Alison W Rebman, John N Aucott,

It has long been observed in clinical practice that a subset of patients with Lyme disease report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal pain, which may last for a significant period of time. These symptoms, which can range from mild to severe, have been reported ... Read more >>

Front Med (Lausanne) (Frontiers in Medicine)
[2020, 7:57]

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Endocannabinoid-Mediated Neuromodulation in the Olfactory Bulb: Functional and Therapeutic Significance.

Naina Bhatia-Dey, Thomas Heinbockel,

Endocannabinoid synthesis in the human body is naturally occurring and on-demand. It occurs in response to physiological and environmental stimuli, such as stress, anxiety, hunger, other factors negatively disrupting homeostasis, as well as the therapeutic use of the phytocannabinoid cannabidiol and recreational use of exogenous cannabis, which can lead to ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2020, 21(8):]

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Multiple pulmonary nodules in granulomatous polyangiitis: A case series.

Itthiphat Arunsurat, Wipa Reechaipichitkul, Apichart So-Ngern, Nipon Chaisuriya, Ajanee Mahankkanukrauh, Pailin Ratanawatkul, Worawat Chumpangern, Pongsakorn Kampan,

Granulomatous polyangiitis (GPA) is a multiple systemic necrotizing vasculitis. Diagnosis of pulmonary nodules in GPA is still challenging in clinical practice, however, other extrapulmonary manifestations, serology, and histopathology may help the diagnosis of GPA. This case series was of limed GPA with one of the largest pulmonary nodules which had ... Read more >>

Respir Med Case Rep (Respiratory Medicine Case Reports)
[2020, 30:101043]

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Tick Cell Lines in Research on Tick Control.

Ahmed Al-Rofaai, Lesley Bell-Sakyi,

Ticks and the diseases they transmit are of huge veterinary, medical and economic importance worldwide. Control of ticks attacking livestock and companion animals is achieved primarily by application of chemical or plant-based acaricides. However, ticks can rapidly develop resistance to any new product brought onto the market, necessitating an ongoing ... Read more >>

Front Physiol (Frontiers in Physiology)
[2020, 11:152]

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Seroprevalence of Lymes disease in the Nagarahole and Bandipur forest areas of South India.

Kalpana Babu, Krishna R Murthy, M Bhagya, Praveen R Murthy, Vinuth N Puttamallesh, V Ravi,

Purpose:The aim of this study was to determine the seroprevalence of Lymes disease in a population at risk in south India. Methods:Prospective ongoing study and included screening of forest workers and staff of Nagarahole and Bandipur forest ranges in South India for Lymes disease. Screening included a detailed questionnaire for ... Read more >>

Indian J Ophthalmol (Indian journal of ophthalmology)
[2020, 68(1):100-105]

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Caffeine Consumption in Children: Innocuous or Deleterious? A Systematic Review.

Yeyetzi C Torres-Ugalde, Angélica Romero-Palencia, Alma D Román-Gutiérrez, Deyanira Ojeda-Ramírez, Rebeca M E Guzmán-Saldaña,

Caffeine is the most consumed psychostimulant worldwide. Its use among children is controversial. Although it produces an increase in brain activity, it could hamper growth and development in young consumers. Therefore, the aim of this review was to recognize changes produced by caffeine in children under 12 years of age ... Read more >>

Int J Environ Res Public Health (International journal of environmental research and public health)
[2020, 17(7):]

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Psychiatric Presentation of Anti-NMDA Receptor Encephalitis.

Dominique Endres, Sebastian Rauer, Winfried Kern, Nils Venhoff, Simon J Maier, Kimon Runge, Patrick Süß, Bernd Feige, Kathrin Nickel, Timo Heidt, Katharina Domschke, Karl Egger, Harald Prüss, Philipp T Meyer, Ludger Tebartz van Elst,

Background: Anti-N-methyl D-aspartate (NMDA) receptor encephalitis is an autoimmune condition characterized by neuropsychiatric symptoms, including epileptic seizures, movement disorders, autonomic instability, disturbances of consciousness, paranoia, delusions, and catatonia. Ovarian teratomas and viral infections, typically Herpes simplex viruses, have previously been demonstrated to precipitate anti-NMDA receptor encephalitis, but in many cases, ... Read more >>

Front Neurol (Frontiers in Neurology)
[2019, 10:1086]

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An Appraisal of Antidotes' Effectiveness: Evidence of the Use of Phyto-Antidotes and Biotechnological Advancements.

Christiana Eleojo Aruwa, Yusuf Ola Mukaila, Abdulwakeel Ayokun-Nun Ajao, Saheed Sabiu,

Poisoning is the greatest source of avoidable death in the world and can result from industrial exhausts, incessant bush burning, drug overdose, accidental toxication or snake envenomation. Since the advent of Albert Calmette's cobra venom antidote, efforts have been geared towards antidotes development for various poisons to date. While there ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2020, 25(7):]

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Lactoferrin infant feeding trial_Canada (LIFT_Canada): protocol for a randomized trial of adding lactoferrin to feeds of very-low-birth-weight preterm infants.

Elizabeth V Asztalos, Keith Barrington, Abhay Lodha, William Tarnow-Mordi, Andrew Martin,

BACKGROUND:In Canada alone, almost 3000 VLBW infants are born and treated annually with almost 1200 going onto death or survival with severe brain injury, chronic lung disorders, aggressive retinopathy of prematurity, late-onset sepsis, or significant necrotizing enterocolitis. Lactoferrin is an antimicrobial, antioxidant, anti-inflammatory iron-carrying, bifidogenic glycoprotein found in all vertebrates ... Read more >>

BMC Pediatr (BMC pediatrics)
[2020, 20(1):40]

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Antecedent infections in Guillain-Barré syndrome: a single-center, prospective study.

Yanlei Hao, Weifang Wang, Bart C Jacobs, Baojun Qiao, Mengshi Chen, Daiqiang Liu, Xungang Feng, Yuzhong Wang,

OBJECTIVE:To investigate the spectrum of antecedent infections in Chinese patients with Guillain-Barré syndrome (GBS) and analyze the infections-related clinical phenotypes locally. METHODS:A prospective case-control study of 150 patients diagnosed with GBS and age- and sex-matched neurological and healthy controls was performed to investigate recent infections of 14 pathogens serologically and ... Read more >>

Ann Clin Transl Neurol (Annals of clinical and translational neurology)
[2019, 6(12):2510-2517]

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Recreational 'mud fever': Leptospira interrogans induced diffuse alveolar hemorrhage and severe acute respiratory distress syndrome in a U.S. Navy seaman following 'mud-run' in Hawaii.

Sarah A Schmalzle, Ali Tabatabai, Michael Mazzeffi, Ann Matta, Allison Hollis, Marc Zubrow, Keshava Rajagopal, Kerri Thom, Thomas Scalea,

A 23-year-old man with a viral-like prodrome developed sudden severe dyspnea and was found to have renal failure, anemia, shock, and diffuse alveolar hemorrhage with acute respiratory distress syndrome, requiring emergent endotracheal intubation and extracorporeal membrane oxygenation (ECMO). Travel and exposure history from peripheral sources revealed that the patient had ... Read more >>

IDCases (IDCases)
[2019, 15:e00529]

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General Infectious Disease Question and Answer Items.

Christine M. Houser,

An overview of the general pediatric infectious disease topics necessary for ward knowledge, clinical acumen in practice, and board examination preparation is presented in an easy-to-study question & answer format. ... Read more >>

Pediatr Infect Dis (Pediatric infectious disease)
[0, :27-187]

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Facial paralysis as a presenting symptom of infant leukemia: A case report and literature review.

Liyuan Wang, Zhiling Wang, Chaomin Wan, Xiaotang Cai, Ge Zhang, Chunqi Lai,

RATIONALE:Facial paralysis as the initial clinical presentation of infant leukemia (IL) is rare, and the rate of its misdiagnosis is high. Identifying the clinical characteristics of IL with facial paralysis as the initial symptom is necessary to improve the understanding of the causes of facial paralysis and IL. PATIENT CONCERNS:A ... Read more >>

Medicine (Baltimore) (Medicine)
[2018, 97(51):e13673]

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Comparative analysis of viruses in four bee species collected from agricultural, urban, and natural landscapes.

Tugce Olgun, Sydney E Everhart, Troy Anderson, Judy Wu-Smart,

Managed honey bees (Apis mellifera L.) and wild bees provide critical ecological services that shape and sustain natural, agricultural, and urban landscapes. In recent years, declines in bee populations have highlighted the importance of the pollination services they provide and the need for more research into the reasons for global ... Read more >>

PLoS ONE (PloS one)
[2020, 15(6):e0234431]

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The utility of peripheral blood leucocyte ratios as biomarkers in infectious diseases: A systematic review and meta-analysis.

Clark D Russell, Arun Parajuli, Hugo J Gale, Naomi S Bulteel, Philipp Schuetz, Cornelis P C de Jager, Anne J M Loonen, Georgios I Merekoulias, J Kenneth Baillie,

OBJECTIVES:To assess the utility of the neutrophil:lymphocyte (NLR), lymphocyte:monocyte (LMR) and platelet:lymphocyte ratios (PLR) as infection biomarkers. METHODS:PubMed/MEDLINE, Embase and Cochrane databases were searched to identify eligible articles. Studies of diagnosis, severity or outcome were included. PROSPERO systematic review registration CRD42017075032. RESULTS:Forty studies were included, reporting on bacterial and viral ... Read more >>

J. Infect. (The Journal of infection)
[2019, 78(5):339-348]

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Rhinocerebral mucormycosis after functional endoscopic sinus surgery: A case report.

Cha Dong Yeo, Jong Seung Kim, Sam Hyun Kwon, Eun Jung Lee, Min Hee Lee, Su Geun Kim, Yeon Seok You, June Sun Kim, Jong Hwan Lee, Ji Seob Ryu,

RATIONALE:Mucormycosis is a rare fungal infection which mainly develops in compromised hosts and the associated mortality rate is high. PATIENT CONCERNS:We report a case of mucormycosis in a 59-year-old woman following routine endoscopic sinus surgery. The patient had a history of diabetes mellitus (DM) and bronchial asthma. DIAGNOSES:On follow-up 4 ... Read more >>

Medicine (Baltimore) (Medicine)
[2018, 97(51):e13290]

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Myomesin is part of an integrity pathway that responds to sarcomere damage and disease.

Kendal Prill, Casey Carlisle, Megan Stannard, Pamela J Windsor Reid, David B Pilgrim,

The structure and function of the sarcomere of striated muscle is well studied but the steps of sarcomere assembly and maintenance remain under-characterized. With the aid of chaperones and factors of the protein quality control system, muscle proteins can be folded and assembled into the contractile apparatus of the sarcomere. ... Read more >>

PLoS ONE (PloS one)
[2019, 14(10):e0224206]

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"Smelling and Tasting" Parkinson's Disease: Using Senses to Improve the Knowledge of the Disease.

Valentina Oppo, Marta Melis, Melania Melis, Iole Tomassini Barbarossa, Giovanni Cossu,

Among non-motor manifestations of Parkinson's Disease (PD), peripheral, sensory symptoms are particularly relevant. Smell dysfunction starts very early and frequently precedes the PD motor symptoms by years (being often a cue to the diagnosis). Moreover, olfactory system could be, together with gut, one of those peripheral sites where PD pathology ... Read more >>

Front Aging Neurosci (Frontiers in Aging Neuroscience)
[2020, 12:43]

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Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease.

Andrew C Giles, Brock Grill,

Huwe1 is a highly conserved member of the HECT E3 ubiquitin ligase family. Here, we explore the growing importance of Huwe1 in nervous system development, function and disease. We discuss extensive progress made in deciphering how Huwe1 regulates neural progenitor proliferation and differentiation, cell migration, and axon development. We highlight ... Read more >>

Neural Dev (Neural development)
[2020, 15(1):6]

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Acute Neonatal Respiratory Failure.

Desmond Bohn, Peter A. Dargaville, Peter G. Davis, Alastair A. Hutchison, Louise S. Owen,

Acute respiratory failure requiring assisted ventilation is one of the most common reasons for admission to the neonatal intensive care unit. Respiratory failure is the inability to maintain either normal delivery of oxygen to the tissues or normal removal of carbon dioxide from the tissues. It occurs when there is ... Read more >>

(Pediatric and Neonatal Mechanical Ventilation)
[0, :1185-1265]

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The International Network for Evaluating Outcomes (iNeo) of neonates: evolution, progress and opportunities.

Prakesh S Shah, Kei Lui, Brian Reichman, Mikael Norman, Satoshi Kusuda, Liisa Lehtonen, Mark Adams, Maximo Vento, Brian A Darlow, Neena Modi, Franca Rusconi, Stellan Håkansson, Laura San Feliciano, Kjell K Helenius, Dirk Bassler, Shinya Hirano, Shoo K Lee,

Neonates born very preterm (before 32 weeks' gestational age), are a significant public health concern because of their high-risk of mortality and life-long disability. In addition, caring for very preterm neonates can be expensive, both during their initial hospitalization and their long-term cost of permanent impairments. To address these issues, ... Read more >>

Transl Pediatr (Translational pediatrics)
[2019, 8(3):170-181]

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Neurological disorders in HIV in Africa: a review.

William P Howlett,

Background:Neurological disorders in HIV infection are a common cause of morbidity and mortality. The aim of this paper is to provide a narrative overview of up to date information concerning neurological disorders affecting HIV infected persons in Africa. Methods:Seminal research concerning neurological disorders among HIV-infected adults in sub-Saharan Africa from ... Read more >>

Afr Health Sci (African health sciences)
[2019, 19(2):1953-1977]

Cited: 1 time

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Antibiotic regimens for neonatal sepsis - a protocol for a systematic review with meta-analysis.

Steven Kwasi Korang, Sanam Safi, Christian Gluud, Ulrik Lausten-Thomsen, Janus C Jakobsen,

BACKGROUND:Sepsis is a major cause of morbidity and mortality among neonates and infants. Antibiotics are a central part of the first line treatment for sepsis in neonatal intensive care units worldwide. However, the evidence on the clinical effects of the commonly used antibiotic regimens for sepsis in neonates remains scarce. ... Read more >>

Syst Rev (Systematic reviews)
[2019, 8(1):306]

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Invasive rhinocerebral mucormycosis in a patient with liver cirrhosis leading to fatal massive stroke.

Taher Sabobeh, Kamran Mushtaq, Ahmed Elsotouhy, Adham A Ammar, Sameera Rashid,

Immunocompromised status is associated with invasive fungal infections including mucormycosis. These infections are challenging to treat and associated with high overall mortality. Here we report a fatal case of invasive mucormycosis in a cirrhotic, diabetic patient. Despite the swift diagnosis and management; the fungal invasion of the right internal carotid ... Read more >>

Med Mycol Case Rep (Medical Mycology Case Reports)
[2018, 22:69-73]

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Atypical and severe manifestations of chikungunya virus infection in French Guiana: A hospital-based study.

Timothee Bonifay, Christelle Prince, Clarisse Neyra, Magalie Demar, Dominique Rousset, Hatem Kallel, Mathieu Nacher, Félix Djossou, Loïc Epelboin, ,

BACKGROUND:French Guiana (FG) was the first country in South America to declare chikungunya virus infection (CHIKV). The outbreak affected about 16,000 persons between February 2014 and October 2015, with several atypical cases, but only two fatal cases. We aimed to describe the clinical presentation of patients hospitalized for CHIKV infection, ... Read more >>

PLoS ONE (PloS one)
[2018, 13(12):e0207406]

Cited: 2 times

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