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Annotating Putative D. discoideum Proteins Using I-TASSER.

Jacquelyn McCullough, Petra Fey, Ryan J Rahman, Morgan Wallace, Seeta Morey, Kyle Sahlberg, Ethan McGonagle, Danielle Hess, Chance Hatfield, Michaela-Romina Sarmiento, Jordi Velasquez, Richard H Gomer,

Using Gene Ontology annotation in any aspect or using any evidence code, we found that approximately 14% percent of predicted <i>D. discoideum</i> proteins have no GO annotations and no obvious similarity to any annotated protein across diverse organisms. We have been systematically examining these unannotated protein sequences using software that ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Synergistic effects of hmp-2/β-catenin and sma-1H-spectrin on epidermal morphogenesis in Caenorhabditis elegans.

Sydney Wieberg, Harper Euwer, Anna Gerst, Stephanie L Maiden,

The F-actin, spectrin, and microtubule cytoskeletons are important mediators of embryonic epidermal morphogenesis in <i>Caenorhabditis elegans</i>. While SMA-1/β<sub>H</sub>-spectrin is known to organize actin bundles that connect to cadherin-based adhesions, the role of microtubules in the developing epidermis is not well understood. To determine if the spectrin cytoskeleton also plays a ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Swimming exercise reduces native ⍺-synuclein protein species in a transgenic C. elegans model of Parkinson's disease.

Minna Y Schmidt, Manish Chamoli, Gordon J Lithgow, Julie K Andersen,

Exercise has been historically recommended to prevent many disease conditions. Intense exercise in particular, has been shown to be beneficial for Parkinson's disease (PD) - stopping and even reversing symptoms in some patients. Recent research in mammalian animal models of Parkinson's have shown that exercise affects ⍺-synuclein aggregate species, considered ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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The Joubert syndrome protein CEP41 is excluded from the distal segment of cilia in C. elegans.

Sebiha Cevik, Oktay I Kaplan,

Rare diseases are a fundamental issue in today's world, affecting more than 300 million individuals worldwide. According to data from Orphanet and OMIM, about 50-60 new conditions are added to the list of over 6,000 clinically distinct diseases each year, rendering disease diagnosis and treatment even more challenging. Ciliopathies comprise ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Distinct spatiotemporal distribution of Hsp90 under high-heat and mild-heat stress conditions in fission yeast.

Teruaki Takasaki, Naofumi Tomimoto, Takumi Ikehata, Ryosuke Satoh, Reiko Sugiura,

The molecular chaperone Hsp90 is highly conserved from bacteria to mammals. In fission yeast, Hsp90 is essential in many cellular processes and its expression is known to be increased by heat stress (HS). Here, we describe the distinct spatiotemporal distribution of Hsp90 under high-heat stress (HHS: 45˚C) and mild-heat stress ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Corrigendum: A histamine-gated channel is an efficient negative selection marker for C. elegans transgenesis.

[This corrects the article DOI: 10.17912/micropub.biology.000349.]. ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Mutations in the Physcomitrium patens gene encoding Aminodeoxychorismate Synthase confer auxotrophic phenotypes.

Michael J Prigge, Yingluo Wang, Mark Estelle,

To facilitate genetic mapping of developmental mutants of <i>Physcomitrium patens</i>, we produced a genetic marker that combines recessive auxotrophy with dominant positive selection. We first identified the gene affected by the <i>pabB4</i> auxotrophic mutation and then replaced it with a cassette that confers antibiotic resistance. This strain may be used ... Read more >>

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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A histamine-gated channel is an efficient negative selection marker for C. elegans transgenesis.

Sonia El Mouridi, Sarah AlHarbi, Christian Frøkjær-Jensen,

MicroPubl Biol (microPublication biology)
[2021, 2021:]

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Genetic analysis of the interaction between the N- and C-terminal halves of UNC-112 (kindlin).

Hiroshi Qadota, Yating Luo, Andres F Oberhauser, Guy M Benian,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Glutamatergic transmission regulates locomotory behavior on a food patch in C. elegans.

Trevor Wolf, Ariana Perez, Gareth Harris,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Caenorhabditis elegans larvae undergo early developmental arrest on a diet of Gram-positive bacterium Enterococcus faecalis.

Madhumanti Dasgupta, Nagagireesh Bojanala, Meghana Shashikanth, Varsha Singh,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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UMEPPI: An ultrasensitive detection method for protein-protein interaction.

Mikiya Umeyama, Jun Hirose, Kengo Morohashi,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Auxin does not affect a suite of morphological or behavioral phenotypes in two wild-type C. elegans strains.

Troy A McDiarmid, Lexis D Kepler, Catharine H Rankin,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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A T231E Mutant that Mimics Pathologic Phosphorylation of Tau in Alzheimer's disease Causes Activation of the Mitochondrial Unfolded Protein Response in C. elegans touch neurons.

Sanjib Guha, Sarah Fischer, Anson Cheng, Gail V W Johnson, Keith Nehrke,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Quantitative insight into the combinatorial interactions within MYB-BHLH-WD complex in Arabidopsis thaliana.

Mikiya Umeyama, Kengo Morohashi,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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The salt-inducible kinase KIN-29 regulates lifespan via the class II histone-deacetylase HDA-4.

Tatiana Nikooei, Aja McDonagh, Alexander M van der Linden,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Generating reliable hypomorphic phenocopies by RNAi using long dsRNA as diluent.

Kimberly N Bekas, Bryan T Phillips,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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The C. elegans TRPV channel proteins OSM-9 and OCR-2 contribute to aversive chemical sensitivity.

Emily A Mehle, Savannah E Sojka, Medha K C, Rosy M Zel, Sebastian J Reese, Denise M Ferkey,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

Cited: 1 time

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Expression of a FRET-based ATP Biosensor in the C. elegans Intestine.

Jose Soto, Madeline Rivera, Gina Broitman-Maduro, Morris F Maduro,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Exposing a novel genetic interaction between unc-33/CRMP and hmp-2/β-catenin during Caenorhabditis elegans embryogenesis.

John Garzanelli, Stephanie Maiden,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Plant hexokinase phylogenetic analysis highlights a possible regulation by the posttranslational modifier SUMO.

Pedro Humberto Castro, Sara Freitas, Herlander Azevedo,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Role of GLD-3 in suppression of the germline stem cell fate.

Ariz Mohammad, Jian Chen, Tim Schedl,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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The C. elegans CEPsh glia are largely dispensable for stress-induced sleep.

Rony Soto, Cheryl Van Buskirk,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Kavain suppresses human Aβ-induced paralysis in C. elegans.

Manish Chamoli, Shankar J Chinta, Julie K Andersen, Gordon J Lithgow,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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Regulation of sleep by KIN-29 is not developmental.

Jeremy J Grubbs, Alexander M van der Linden, David M Raizen,

MicroPubl Biol (microPublication biology)
[2020, 2020:]

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