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Effect of DMSO on lifespan and physiology in C. elegans : Implications for use of DMSO as a solvent for compound delivery.

Abdelrahman AlOkda, Jeremy M Van Raamsdonk,

Dimethyl sulfoxide (DMSO) is a solvent that has been used for basic and medical research based on its ability to dissolve both polar and non-polar compounds. In order to use DMSO to deliver compounds that may impact longevity or neurodegeneration, it is important to first determine the effects of DMSO ... Read more >>

MicroPubl Biol (microPublication biology)
[2022, 2022:]

Cited: 0 times

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The DYF-5 RCK and CDKL-1 CDKL5 kinases contribute differentially to shape distinct sensory neuron cilia morphologies in C. elegans.

Ashish Kumar Maurya, Piali Sengupta,

The conserved CCRK, RCK, and CDKL5 kinases regulate cilia length in diverse organisms. In <i>C. elegans</i> , DYF-18 CCRK regulates DYF-5 RCK to shape both simple and complex cilia morphologies. The CDKL5 ortholog CDKL-1 has also been suggested to act downstream of DYF-18 but independently of DYF-5 to regulate lengths ... Read more >>

MicroPubl Biol (microPublication biology)
[2022, 2022:]

Cited: 0 times

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