Full Text Journal Articles by
Author Ziyi Jin

Advertisement

Find full text journal articles








Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.

Günter U Höglinger, Irene Litvan, Nuno Mendonca, Deli Wang, Hui Zheng, Beatrice Rendenbach-Mueller, Hoi-Kei Lon, Ziyi Jin, Nahome Fisseha, Kumar Budur, Michael Gold, Davis Ryman, Hana Florian, ,

<h4>Background</h4>Progressive supranuclear palsy is a neurodegenerative disorder associated with tau protein aggregation. Tilavonemab (ABBV-8E12) is a monoclonal antibody that binds to the N-terminus of human tau. We assessed the safety and efficacy of tilavonemab for the treatment of progressive supranuclear palsy.<h4>Methods</h4>We did a phase 2, multicentre, randomised, placebo-controlled, double-blind study ... Read more >>

Lancet Neurol (The Lancet. Neurology)
[2021, 20(3):182-192]

Cited: 0 times

View full text PDF listing >>



Response to: 'Correspondence on 'Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the Global Burden of Disease study 2017' by Chiang et al.

Ziyi Jin, Jinkou Zhao, Lingyun Sun,

Ann Rheum Dis (Annals of the rheumatic diseases)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Advertisement

Creatinine clearance rate predicts prognosis of patients with systemic lupus erythematosus: a large retrospective cohort study.

Jiahuan Ge, Ziyi Jin, Xuebing Feng, Wenyou Pan, Lin Liu, Min Wu, Huaixia Hu, Xiang Ding, Hua Wei, Yaohong Zou, Xian Qian, Meimei Wang, Jian Wu, Juan Tao, Jun Tan, Zhanyun Da, Miaojia Zhang, Jing Li, Lingyun Sun,

<h4>Objective</h4>To explore the association between the creatinine clearance rate (Ccr) and the prognosis of patients, and compared with estimated glomerular filtration rate (eGFR).<h4>Methods</h4>We retrospectively collected information of patients with SLE who were first hospitalized between 1999 and 2009 in Jiangsu Province, China, and followed up in 2010 and 2015. Ccr ... Read more >>

Clin Rheumatol (Clinical rheumatology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Factors associated with event-free survival in Chinese patients with Takayasu's arteritis.

Yu Wei, Cheng Zhao, Jun Liang, Ziyi Jin, Bingzhu Hua, Hong Wang, Huayong Zhang, Xuebing Feng,

<h4>Objectives</h4>To investigate long-term outcomes of Takayasu's arteritis (TA) and explore the predictive factors associated with poor prognosis.<h4>Methods</h4>We performed a retrospective study on consecutive TA patients admitted to the Nanjing Drum Tower Hospital during the period from July 2010 to March 2019. Potential factors contributing to adverse outcomes, including death, vascular ... Read more >>

Clin Rheumatol (Clinical rheumatology)
[2020, :]

Cited: 0 times

View full text PDF listing >>



Association of antimalarial drugs with decreased overall and cause specific mortality in systemic lupus erythematosus.

Ziyi Jin, Fan Wang, Wenyou Pan, Lin Liu, Min Wu, Huaixia Hu, Xiang Ding, Hua Wei, Yaohong Zou, Xian Qian, Meimei Wang, Jian Wu, Juan Tao, Jun Tan, Zhanyun Da, Miaojia Zhang, Jing Li, Xuebing Feng, Lingyun Sun,

<h4>Objective</h4>To evaluate the association and dose-response pattern between antimalarial drugs and overall and cause specific mortality in SLE patients.<h4>Methods</h4>Medical records including information on HCQ/chloroquine (CQ) prescription were extracted from Jiangsu Lupus database. The database was designed to collect data from SLE patients that first-hospitalized during 1999-2009 in Jiangsu province, China, ... Read more >>

Rheumatology (Oxford) (Rheumatology (Oxford, England))
[2020, :]

Cited: 0 times

View full text PDF listing >>



Effect of solid-state fermentation with Lactobacillus casei on the nutritional value, isoflavones, phenolic acids and antioxidant activity of whole soybean flour

Songlin Li, Ziyi Jin, Dianjie Hu, Wenwen Yang, Yongyong Yan, Xiaobao Nie, Jing Lin, Qingyu Zhang, Di Gai, Yuxiang Ji, Xiaoming Chen,

This work researched the effect of solid-state fermentation (SSF) with Lactobacillus casei on the changes of nutritional components, isoflavones, phenolic acids and antioxidant activity of whole soybean flour (WSF). Results showed that total protein, vitamin B1, vitamin B2, and β-carotene of WSF increased after fermentation. Fermented whole soybean flour (FWSF) ... Read more >>

Lebensm Wiss Technol (Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire)
[2020, 125:Not Available]

Cited: 0 times

View full text PDF listing >>



Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017.

Ziyi Jin, Dandan Wang, Huayong Zhang, Jun Liang, Xuebing Feng, Jinkou Zhao, Lingyun Sun,

OBJECTIVE:To assess cause-specific incidence and its trend of musculoskeletal (MSK) disorders at global, regional and national levels. METHODS:Data on MSK disorders were downloaded from the Global Burden of Disease 2017 study website. Estimated annual percentage change (EAPC) was calculated to quantify the temporal trend in age-standardised incidence rate (ASR) of ... Read more >>

Ann Rheum Dis (Annals of the rheumatic diseases)
[2020, 79(8):1014-1022]

Cited: 0 times

View full text PDF listing >>



Surface-Enhanced Resonance Raman Scattering-Guided Brain Tumor Surgery Showing Prognostic Benefit in Rat Models.

Limei Han, Wenjia Duan, Xinwei Li, Cong Wang, Ziyi Jin, Yuting Zhai, Chong Cao, Luo Chen, Wenjing Xu, Ying Liu, Yong-Yan Bi, Jianfeng Feng, Ying Mao, Qi Yue, Xiao-Yong Zhang, Cong Li,

Glioma is the most frequent form of malignant brain tumors. Surgical debulking is a major strategy for glioma treatment. However, there is a great challenge for the neurosurgeons to intraoperatively identify the true margins of glioma because of its infiltrative nature. Tumor residues or microscopic satellite foci left in the ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2019, 11(17):15241-15250]

Cited: 0 times

View full text PDF listing >>



Pharmacokinetics, Safety, Tolerability, and Pharmacodynamics of Alicapistat, a Selective Inhibitor of Human Calpains 1 and 2 for the Treatment of Alzheimer Disease: An Overview of Phase 1 Studies.

Hoi-Kei Lon, Nuno Mendonca, Sandra Goss, Ahmed A Othman, Ahmed A Othman, Charles Locke, Ziyi Jin, Beatrice Rendenbach-Mueller,

Alicapistat is an orally active selective inhibitor of calpain 1 and 2 whose overactivation has been linked to Alzheimer disease (AD). Three studies were conducted in healthy subjects (18-55 years), 1 in healthy elderly subjects (≥65 years), and 1 in patients with mild to moderate AD. Four studies assessed pharmacokinetics, 1 study ... Read more >>

Clin Pharmacol Drug Dev (Clinical pharmacology in drug development)
[2019, 8(3):290-303]

Cited: 1 time

View full text PDF listing >>



Methotrexate Dose in Patients With Early Rheumatoid Arthritis Impacts Methotrexate Polyglutamate Pharmacokinetics, Adalimumab Pharmacokinetics, and Efficacy: Pharmacokinetic and Exposure-response Analysis of the CONCERTO Trial.

Sandra L Goss, Cheri E Klein, Ziyi Jin, Charles S Locke, Ramona C Rodila, Hartmut Kupper, Gerd-Rudiger Burmester, Walid M Awni,

PURPOSE:Methotrexate (MTX) and adalimumab are well-recognized treatments of rheumatoid arthritis (RA), the efficacy of which may be driven by intracellular polyglutamates (PGs). The aim of this analysis was to characterize MTX PG concentrations and adalimumab pharmacokinetics in the CONCERTO trial. In addition, the relationships between MTX dose/pharmacokinetics, adalimumab pharmacokinetics, and ... Read more >>

Clin Ther (Clinical therapeutics)
[2018, 40(2):309-319]

Cited: 5 times

View full text PDF listing >>



Tobacco and alcohol use among drug users receiving methadone maintenance treatment: a cross-sectional study in a rural prefecture of Yunnan Province, Southwest China.

Song Duan, Ziyi Jin, Xing Liu, Yuecheng Yang, Runhua Ye, Renhai Tang, Meiyang Gao, Yingying Ding, Na He,

<h4>Objective</h4>To estimate the prevalence of ever, current and heavy tobacco and alcohol use and their correlates among patients undergoing methadone maintenance treatment (MMT).<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>The study was conducted in all of the 5 MMT clinics in Dehong Prefecture, China.<h4>Participants</h4>2121 (81.6%) eligible MMT participants were included in the study population.<h4>Analysis</h4>Ordinal logistic regression ... Read more >>

BMJ Open (BMJ open)
[2017, 7(3):e014643]

Cited: 5 times

View full text PDF listing >>



Research on medical image encryption in telemedicine systems.

Yin Dai, Huanzhen Wang, Zixia Zhou, Ziyi Jin,

Recently, advances in computers and high-speed communication tools have led to enhancements in remote medical consultation research. Laws in some localities require hospitals to encrypt patient information (including images of the patient) before transferring the data over a network. Therefore, developing suitable encryption algorithms is quite important for modern medicine. ... Read more >>

Technol Health Care (Technology and health care : official journal of the European Society for Engineering and Medicine)
[2016, 24 Suppl 2:S435-42]

Cited: 2 times

View full text PDF listing >>





Advertisement

Disclaimer
0.8324 s