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Author Zifan Liu

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Effect of limb rotation on radiographic alignment measurement in mal-aligned knees.

Xiaoshu Sun, Bin Yang, Shengzhao Xiao, Yichen Yan, Zifan Liu, Liang Yuan, Xiaohua Wang, Bin Sun, Jie Yao, Yubo Fan,

<h4>Purpose</h4>Long-leg-radiography (LLR) is commonly used for the measurement of lower limb alignment. However, limb rotations during radiography may interfere with the alignment measurement. This study examines the effect of limb rotation on the accuracy of measurements based on the mechanical and anatomical axes of the femur and tibia, with variations ... Read more >>

Biomed Eng Online (Biomedical engineering online)
[2021, 20(1):119]

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Prediction of HER2 expression in breast cancer by combining PET/CT radiomic analysis and machine learning.

Yiwen Chen, Ziyang Wang, Guotao Yin, Chunxiao Sui, Zifan Liu, Xiaofeng Li, Wei Chen,

<h4>Background</h4>Human epidermal growth factor receptor 2 (HER2) expression status determination significantly contributes to HER2-targeted therapy in breast cancer (BC). The purpose of this study was to evaluate the role of radiomics and machine learning based on PET/CT images in HER2 status prediction, and to identify the most effective combination of ... Read more >>

Ann Nucl Med (Annals of nuclear medicine)
[2021, :]

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WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity.

Guohui Zhong, Dingsheng Zhao, Jianwei Li, Zifan Liu, Junjie Pan, Xinxin Yuan, Wenjuan Xing, Yinglong Zhao, Shukuan Ling, Yingxian Li,

Cardiac muscle is extremely sensitive to changes in loading conditions; the microgravity during space flight can cause cardiac remodeling and function decline. At present, the mechanism of microgravity-induced cardiac remodeling remains to be revealed. WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is an important activator of pressure overload-induced cardiac ... Read more >>

Front Cell Dev Biol (Frontiers in cell and developmental biology)
[2021, 9:739944]

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3' untranslated region of Ckip-1 inhibits cardiac hypertrophy independently of its cognate protein.

Yinlong Zhao, Shukuan Ling, Jianwei Li, Guohui Zhong, Ruikai Du, Youyou Li, Yanqing Wang, Caizhi Liu, Xiaoyan Jin, Wei Liu, Tong Liu, Yuheng Li, Dingsheng Zhao, Weijia Sun, Zizhong Liu, Zifan Liu, Junjie Pan, Xinxin Yuan, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li,

<h4>Aims</h4>3' untranslated region (3' UTR) of mRNA is more conserved than other non-coding sequences in vertebrate genomes, and its sequence space has substantially expanded during the evolution of higher organisms, which substantiates their significance in biological regulation. However, the independent role of 3' UTR in cardiovascular disease was largely unknown.<h4>Methods ... Read more >>

Eur Heart J (European heart journal)
[2021, 42(36):3786-3799]

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Anti-inflammatory Therapies for Coronary Heart Disease: A Systematic Review and Meta-Analysis.

Haiming Wang, Min Jiang, Xin Li, Yunzhang Zhao, Junjie Shao, Zifan Liu, Lejian Lin, Qiang Xu, Lin Wang, Xuechun Lu, Haomin Zhang, Yundai Chen, Ran Zhang,

<b>Background:</b> Anti-inflammatory therapy has been proposed as a promising treatment for coronary heart disease (CHD) that could reduce residual inflammation risk (RIR) and therefore major adverse cardiovascular events. We implemented a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the clinical benefits of anti-inflammatory agents in patients ... Read more >>

Front Cardiovasc Med (Frontiers in cardiovascular medicine)
[2021, 8:726341]

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Effect of limb rotation on radiographic alignment measurement in mal-aligned knees

Xiaoshu Sun, Bin Yang, Shengzhao Xiao, Yichen Yan, Zifan Liu, Liang Yuan, Xiaohua Wang, Bin Sun, Jie Yao, Yubo Fan,

<h4>Purpose: </h4> Long-leg-radiography (LLR) is commonly used for measurement of lower limb alignment. However, limb rotations during radiography may interfere with the alignment measurement. This study examines the effect of limb rotation on the accuracy of measurements based on the mechanical and anatomical axes of the femur and tibia, with ... Read more >>

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The next generation therapy for lung cancer: taking medicine by inhalation.

Ziyao Wang, Zifan Liu, Jie Mei, Shanshan Xu, Ying Liu,

The inhalation administration method which has been applied to treat respiratory diseases has the characteristics of painlessness high efficiency and non-invasiveness, and the drug can also be targeted at the organ level first to reduce the loss of drug during circulation. Therefore, delivering medicine by inhalation administration has brought a ... Read more >>

Nanotechnology (Nanotechnology)
[2021, 32(39):]

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WWP1 deficiency protects from cardiac remodeling induced by simulated microgravity

Guohui Zhong, Dingsheng Zhao, Jianwei Li, Zifan Liu, Junjie Pan, Xinxin Yuan, Wenjuan Xing, Yinglong Zhao, Shukuan Ling, Yingxian Li,

Cardiac muscle is extremely sensitive to changes in loading conditions, the microgravity during space flight can cause cardiac remodeling and function decline. At present, the mechanism of microgravity-induced cardiac remodeling remains to be revealed. WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is an important activator of pressure-overload induced cardiac ... Read more >>

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Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination.

Dingsheng Zhao, Guohui Zhong, Jianwei Li, Junjie Pan, Yinlong Zhao, Hailin Song, Weijia Sun, Xiaoyan Jin, Yuheng Li, Ruikai Du, Jielin Nie, Tong Liu, Junmeng Zheng, Yixin Jia, Zifan Liu, Wei Liu, Xinxin Yuan, Zizhong Liu, Jinping Song, Guanghan Kan, Youyou Li, Caizhi Liu, Xingcheng Gao, Wenjuan Xing, Yan-Zhong Chang, Yingxian Li, Shukuan Ling,

<h4>Background</h4>Without adequate treatment, pathological cardiac hypertrophy induced by sustained pressure overload eventually leads to heart failure. WWP1 (WW domain-containing E3 ubiquitin protein ligase 1) is an important regulator of aging-related pathologies, including cancer and cardiovascular diseases. However, the role of WWP1 in pressure overload-induced cardiac remodeling and heart failure is ... Read more >>

Circulation (Circulation)
[2021, 144(9):694-711]

Cited: 2 times

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Adaptive digital filter for the processing of atmospheric lidar signals measured by imaging lidar techniques.

Zifan Liu, Chenguang Yang, Zhenfeng Gong, Hui Li, Liang Mei,

The lidar signal measured by the atmospheric imaging lidar technique is subject to sunlight background noise, dark current noise, and fixed pattern noise (FPN) of the image sensor, etc., which presents quite different characteristics compared to the lidar signal measured by the pulsed lidar technique based on the time-of-flight principle. ... Read more >>

Appl Opt (Applied optics)
[2020, 59(30):9454-9463]

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Endoplasmic reticulum stress-dependent activation of iNOS/NO-NF-κB signaling and NLRP3 inflammasome contributes to endothelial inflammation and apoptosis associated with microgravity.

Min Jiang, Haiming Wang, Zifan Liu, Lejian Lin, Lin Wang, Manjiang Xie, Danyang Li, Jibin Zhang, Ran Zhang,

Exposure to microgravity results in vascular remodeling and cardiovascular dysfunction. To elucidate the mechanism involved in this condition, we investigated whether endoplasmic reticulum (ER) stress during simulated microgravity induced endothelial inflammation and apoptosis in human umbilical vein endothelial cells (HUVECs). Microgravity was simulated by clinorotation in the current study. We ... Read more >>

FASEB J (FASEB journal : official publication of the Federation of American Societies for Experimental Biology)
[2020, 34(8):10835-10849]

Cited: 8 times

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Posterior reversible encephalopathy syndrome in preeclampsia and eclampsia: The role of hypomagnesemia.

Xiaobo Fang, Haibin Wang, Zifan Liu, Jia Chen, Hu Tan, Yanling Liang, Dunjin Chen,

PURPOSE:Posterior reversible encephalopathy syndrome (PRES), defined by its clinical and imaging manifestations, is a critical maternal complication. The specific pathophysiological mechanism of PRES has not been fully elucidated and remains controversial. Recently, several case studies reported that hypomagnesemia is present in the acute phase of PRES regardless of its etiology. ... Read more >>

Seizure (Seizure)
[2020, 76:12-16]

Cited: 3 times

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Glutamic Acid Decarboxylase Antibody in a Patient with Myelitis: A Retrospective Study.

Zifan Liu, Qingmei Huang, Huijuan Li, Wei Qiu, Baikeng Chen, Jie Luo, Huacai Yang, Tianni Liu, Si Liu, Huiming Xu, Youming Long, Cong Gao,

<h4>Objective</h4>The aim of this study was to evaluate the positive rate of serum glutamic acid decarboxylase (GAD) autoantibody in patients with myelitis and to describe the clinical findings in patients with positive GAD antibody.<h4>Methods</h4>Serum samples were collected from 390 patients with myelitis, including 210 patients positive for aquaporin 4 (AQP4) ... Read more >>

Neuroimmunomodulation (Neuroimmunomodulation)
[2018, 25(2):68-72]

Cited: 2 times

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Naturalistic drive cycle synthesis for pickup trucks.

Zifan Liu, Andrej Ivanco, Zoran Filipi,

<h4>Problem</h4>Future pick-up trucks are meeting much stricter fuel economy and exhaust emission standards. Design tradeoffs will have to be carefully evaluated to satisfy consumer expectations within the regulatory and cost constraints. Boundary conditions will obviously be critical for decision making: thus, the understanding of how customers are driving in naturalistic ... Read more >>

J Safety Res (Journal of safety research)
[2015, 54:109-115]

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