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Author Zhiyuan Li

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Mycotoxins detection: view in the lens of molecularly imprinted polymer and nanoparticles.

Daniel Mukunzi, Jean de Dieu Habimana, Zhiyuan Li, Xiaobo Zou,

Molecularly imprinted polymers (MIPs) are tailor-made functional composites which selectively recognize and bind the target molecule of interest. MIP composites are products of the massively cross-linked polymer matrices, generated via polymerization, with bio-inspired recognition cavities that are morphologically similar in size, shape and spatial patterns to the target conformation. These ... Read more >>

Crit Rev Food Sci Nutr (Critical reviews in food science and nutrition)
[2022, :1-35]

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Hypochlorous Acid Can Be the Novel Option for the Meibomian Gland Dysfunction Dry Eye through Ultrasonic Atomization.

Zhiyuan Li, Haiyan Wang, Mo Liang, Zhenghua Li, Yvliang Li, Xiaoping Zhou, Guoping Kuang,

<h4>Background</h4>Dry eye is a multifactor disease which needs comprehensive treatments to keep the homeostasis of ocular surface.<h4>Objective</h4>To explore the effect of hypochlorous acid on the meibomian gland dysfunction dry eye through ultrasonic atomization.<h4>Methods</h4>We set this study of 0.01% HOCL and 0.1% hyaluronate by ultrasonic atomization. All the data was recorded ... Read more >>

Dis Markers (Disease markers)
[2022, 2022:8631038]

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Rational Programming of Cas12a for Early-Stage Detection of COVID-19 by Lateral Flow Assay and Portable Real-Time Fluorescence Readout Facilities.

Zhijian Yi, Jean de Dieu Habimana, Omar Mukama, Zhiyuan Li, Nelson Odiwuor, Hanzhi Jing, Chengrong Nie, Mei Hu, Zuoxian Lin, Hongping Wei, Lingwen Zeng,

Coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has led to a global pandemic with a high spread rate and pathogenicity. Thus, with limited testing solutions, it is imperative to develop early-stage diagnostics for rapid and accurate detection of SARS-CoV-2 to contain the rapid transmission of the ongoing COVID-19 ... Read more >>

Biosensors (Basel) (Biosensors)
[2021, 12(1):]

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Identification and functional characterization of gonadotropin -releasing hormone in pompano (Trachinotus ovatus).

Xilin Ren, Yanlin Huang, Xiaomeng Li, Zhiyuan Li, Hao Yang, Ruiqi He, Honggan Zhong, Guangli Li, Huapu Chen,

Gonadotropin-releasing hormone (GnRH) is an important neuropeptide in the reproductive system. Although GnRH analogues have been used to artificially spawn pompano (Trachinotus sp.), the native forms of GnRH have not been described in this species. In this study three GnRH subtypes [sea bream GnRH (sbGnRH), chicken GnRH-Ⅱ (cGnRH-Ⅱ) and salmon ... Read more >>

Gen Comp Endocrinol (General and comparative endocrinology)
[2022, 316:113958]

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Effects of SNPs in SOD2 and SOD3 interacted with fluoride exposure on the susceptibility of dental fluorosis.

Yuhui Du, Xiaoli Fu, Jing Jin, Zhiyuan Li, Kaihong Xu, Meng Guo, Xiangbo Hou, Zichen Feng, Limin Ding, Yongxiang Gong, Bin Liu, Fangfang Yu, Guoyu Zhou, Yue Ba,

A total of 649 children aged 7-13 years of age were recruited in a cross-sectional study in Tongxu County, China (2017) to assess the effects of interaction between single nucleotide polymorphisms (SNPs) in SOD2 and SOD3 gene and fluoride exposure on dental fluorosis (DF) status. Associations between biomarkers and DF ... Read more >>

Int J Hyg Environ Health (International journal of hygiene and environmental health)
[2022, 239:113879]

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A Pyroptosis-Associated Signature Plays a Role in Prognosis Prediction And Indicating Infiltration in Immune Microenvironment in Clear Cell Renal Cell Carcinoma

Zhiyuan Li, Zhinan Xia, Yipeng Yu, Licheng Cai, Wengang Jian, Tengda Wang, Wei Xue, Xingyuan Wang, Bowen Wang, Peng Zhang, Wenhao Yao, Cheng Zhang, Chunyang Wang,

<h4>Background: </h4> About 90% renal malignancies are RCCs (renal cell carcinomas) and the main subtype in histology is ccRCC (clear cell RCC). In recent years, pyroptosis was considered as a kind of inflammation-related programmed cell death, which played a part in the invasion, metastasis and proliferation of tumor cells, thereby ... Read more >>

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Ameliorating Effect of Umbilical Cord Mesenchymal Stem Cells in a Human Induced Pluripotent Stem Cell Model of Dravet Syndrome.

Huifang Zhao, Shuai Li, Lang He, Feng Tang, Xiaobo Han, Weiyue Deng, Zuoxian Lin, Rongqi Huang, Zhiyuan Li,

Dravet syndrome (DS) is a form of severe childhood-onset refractory epilepsy typically caused by a heterozygous loss-of-function mutation. DS patient-derived induced pluripotent stem cells (iPSCs) are appropriate human cells for exploring disease mechanisms and testing new therapeutic strategies in vitro. Repeated spontaneous seizures can cause neuroinflammatory reactions and oxidative stress, ... Read more >>

Mol Neurobiol (Molecular neurobiology)
[2021, :]

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Bacterial Foraging Algorithm With Potential Field Guidance Mechanism

Zhiyuan Li, Zhicheng Wang,

To address the problems of weak quorum sensing ability and slow convergence speed in bacterial foraging algorithm, a bacterial foraging algorithm with potential field guidance mechanism is proposed. The algorithm combines the sampling guidance mechanism in the artificial potential field algorithm to provide the optimization direction for each bacterium; The ... Read more >>

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Fluoride Stimulates Anxiety- and Depression-like Behaviors Associated with SIK2-CRTC1 Signaling Dysfunction.

Guoyu Zhou, Yue Hu, Anqi Wang, Meng Guo, Yuhui Du, Yongxiang Gong, Limin Ding, Zichen Feng, Xiangbo Hou, Kaihong Xu, Fangfang Yu, Zhiyuan Li, Yue Ba,

Using Sprague-Dawley rats and rat PC12 cells treated with sodium fluoride (NaF), we investigated the effects of SIK2-CRTC1 signaling on the neurobehavioral toxicity induced by fluoride. The <i>in vivo</i> results demonstrated that NaF treatment induced anxiety- and depression-like behaviors in juvenile rats, resulting in histological and ultrastructural abnormalities in the ... Read more >>

J Agric Food Chem (Journal of agricultural and food chemistry)
[2021, 69(45):13618-13627]

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Heat-Moisture Treatment Further Reduces In Vitro Digestibility and Enhances Resistant Starch Content of a High-Resistant Starch and Low-Glutelin Rice.

Zhiyuan Li, Dongshu Guo, Xiao Li, Zhaocheng Tang, Xitie Ling, Tiantian Zhou, Baolong Zhang,

A novel rice germplasm <i>sbeIIb</i>/<i>Lgc1</i> producing grains rich in resistant starch (RS) but low in glutelin has been developed through CRISPR/Cas9-mediated targeted mutagenesis for its potential benefits to patients with diabetes and kidney diseases. In this study, a hydrothermal approach known as heat-moisture treatment (HMT) was identified as a simple ... Read more >>

Foods (Foods (Basel, Switzerland))
[2021, 10(11):]

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Hair follicle-derived mesenchymal stem cells decrease alopecia areata mouse hair loss and reduce inflammation around the hair follicle.

Weiyue Deng, Yuying Zhang, Wei Wang, Aishi Song, Omar Mukama, Jiarong Huang, Xiaobo Han, Sihao Deng, Zuoxian Lin, Jean du Dieu Habimana, Rongqi Huang, Kexin Peng, Bing Ni, Shusheng Zhang, Xiaoxin Yan, Ji Li, Lin-Ping Wu, Zhiyuan Li,

<h4>Background</h4>Alopecia areata (AA) is a common autoimmune hair loss disease with increasing incidence. Corticosteroids are the most widely used for hair loss treatment; however, long-term usage of hormonal drugs is associated with various side effects. Mesenchymal stem cells (MSCs) therapy has been studied extensively to curb autoimmune diseases without affecting ... Read more >>

Stem Cell Res Ther (Stem cell research & therapy)
[2021, 12(1):548]

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The neonatal PROC gene rs1799809 polymorphism modifies the association between prenatal air pollutants exposure and PROC promoter methylation.

Zhiyuan Li, Meng Yang, Leizhen Duan, Yongxiang Gong, Hongxia Xia, Francis-Kojo Afrim, Hui Huang, Xiaoxue Liu, Fangfang Yu, Yawei Zhang, Yue Ba, Guoyu Zhou,

Prenatal air pollution, protein C (PROC) gene abnormal methylation, and genetic mutation can cause a series of neonatal diseases, but the complex relationship between them remains unclear. Here, we recruited 552 mothers and their own babies during January 2010-January 2012 in Zhengzhou to explore such association. The air pollutant data ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, :]

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Occurrence and distribution of organophosphate flame retardants in the typical soil profiles of the Tibetan Plateau, China.

Zihao Zhang, Yue Xu, Yan Wang, Zhiyuan Li, Chenmeng Yang, Timothy F M Rodgers, Feng Tan,

The urbanization and development of Tibetan Plateau (TP) probably results in a significant contamination of organic pollutants, such as organophosphate flame retardants (OPFRs). However, there is a lack of monitoring and evaluation of their occurrence and risks in the soil of TP. We investigated the concentrations, vertical distributions, potential sources, ... Read more >>

Sci Total Environ (The Science of the total environment)
[2022, 807(Pt 2):150519]

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CRISPR/Cas9 mediated gene correction ameliorates abnormal phenotypes in spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cells.

Lang He, Shang Wang, Linliu Peng, Huifang Zhao, Shuai Li, Xiaobo Han, Jean de Dieu Habimana, Zhao Chen, Chunrong Wang, Yun Peng, Huirong Peng, Yue Xie, Lijing Lei, Qi Deng, Linlin Wan, Na Wan, Hongyu Yuan, Yiqing Gong, Guangdong Zou, Zhiyuan Li, Beisha Tang, Hong Jiang,

Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is a progressive autosomal dominant neurodegenerative disease caused by abnormal CAG repeats in the exon 10 of ATXN3. The accumulation of the mutant ataxin-3 proteins carrying expanded polyglutamine (polyQ) leads to selective degeneration of neurons. Since the pathogenesis of SCA3 has not been fully ... Read more >>

Transl Psychiatry (Translational psychiatry)
[2021, 11(1):479]

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Proarrhythmic effects induced by benzethonium chloride and domiphen bromide in vitro and in vivo.

Yan Long, Jian Hou, Feng Tang, Zuoxian Lin, Xiaolin Huang, Wei Li, Yili Chen, Zhiyuan Li, Zhongkai Wu,

Benzethonium chloride (BZT) and domiphen bromide (DMP) are widely used as antimicrobials in drugs, vaccines and industry. However, no cardiac safety data has been developed on both compounds. Previously we reported BZT and DMP as high-affinity human ether-a-go-go related gene (HERG) channel inhibitors with unknown proarrhythmic risk. Here, we investigate ... Read more >>

Toxicol Appl Pharmacol (Toxicology and applied pharmacology)
[2021, 431:115731]

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Hemodynamic variation is a dominant contributing factor of Graves’ hyperthyroidism complication: Heart failure and fatal liver disfunction: a case report and analysis

Yi Fang, Zhiyuan Li, Jinjing Wang, Jianbin Su, Jing Zeng, Jian Xue, Xinyu Li,

Tachycardia and atrial fibrillation are cardiovascular symptoms of Graves’ hyperthyroidism, if left untreated and further deterioration can result in heart failure and liver dysfunction, we describe a female patient to present the continuum of the pathophysiology development, to highlight the hemodynamic variation is dominant contributing factor of Graves’ hyperthyroidism complication ... Read more >>

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Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.

Fang-Fang Yu, Juan Zuo, Xiaoli Fu, Ming-Hui Gao, Lei Sun, Shui-Yuan Yu, Zhiyuan Li, Guo-Yu Zhou, Yue Ba,

To identify the role of the Hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure. Environmental response genes (ERGs) of bone injury induced by fluoride exposure were obtained from the Comparative Toxicogenomics Database, and annotated by STRING for KEGG pathway enrichment analysis. The CCK-8 kit ... Read more >>

Ecotoxicol Environ Saf (Ecotoxicology and environmental safety)
[2021, 225:112796]

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Whole-genome sequencing for surveillance of tuberculosis drug resistance and determination of resistance level in China.

Dongxin Liu, Fei Huang, Guoliang Zhang, Wencong He, Xichao Ou, Ping He, Bing Zhao, Baoli Zhu, Fei Liu, Zhiyuan Li, Chunfa Liu, Hui Xia, Shengfen Wang, Yang Zhou, Timothy M Walker, Lei Liu, Derrick W Crook, Yanlin Zhao,

<h4>Objectives</h4>Phenotypic drug susceptibility testing for prediction of tuberculosis (TB) drug resistance is slow and unreliable, limiting individualized therapy and monitoring of national TB data. Our study evaluated whole-genome sequencing (WGS) for its predictive accuracy, use in TB drug-resistance surveillance and ability to quantify the effects of resistance-associated mutations on MICs ... Read more >>

Clin Microbiol Infect (Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases)
[2021, :]

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Transformation of Cr under sintering of Ca-rich solid waste with kaolin: Analysis of multi-element coupled interactions.

Zhicheng Zhu, Yaji Huang, Jianrui Zha, Mengzhu Yu, Haoqiang Cheng, Zhenrong Zhang, Lu Dong, Zhiyuan Li, Conghui Fan,

The high toxicity of Cr-Ca compounds generated during the heat treatment of solid waste will heavily threat the environment. In this work, a kind of Ca-rich river sludge which is bound with Ca and heavy metals was combusted with kaolin under 900 °C for 3 h in a muffle to study the ... Read more >>

Chemosphere (Chemosphere)
[2022, 287(Pt 3):132181]

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A RADIOLUMINESCENCE STUDY OF DOSE CHARACTERISTICS OF LIF:MG,TI.

Siyuan Zhang, Kaiyong Tang, Haijun Fan, Zhiyuan Li, Guangwei Huang, Kun Wu, Li Fu,

A radioluminescence (RL) study of dose characteristics of tissue-equivalent LiF:Mg,Ti was carried out to determine the possible application as a real-time dosemeter. An RL measurements system based on LiF:Mg,Ti coupled with optical fiber was developed, and a blank fiber was set to remove the stem effect generated by the optical ... Read more >>

Radiat Prot Dosimetry (Radiation protection dosimetry)
[2021, 195(2):69-74]

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Carbon and nitrogen metabolism under nitrogen variation affects flavonoid accumulation in the leaves of Coreopsis tinctoria.

Zhiyuan Li, Hong Jiang, Huizhuan Yan, Xiumei Jiang, Yan Ma, Yong Qin,

Flavonoids are phytochemicals present in medicinal plants and contribute to human health. <i>Coreopsis tinctoria</i>, a species rich in flavonoids, has long been used in traditional medicine and as a food resource. N (nitrogen) fertilization can reduce flavonoid accumulation in <i>C. tinctoria</i>. However, there is limited knowledge regarding N regulatory mechanisms. ... Read more >>

PeerJ (PeerJ)
[2021, 9:e12152]

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Clinicopathologic features and BRAF mutation status of tracheal glomus tumors - Characterization of 4 cases and the distinction from low-grade neuroendocrine tumors.

Jie Lin, Jie Luo, Huang Chen, Zhiyuan Li, Yanfen Shi, Hongliang Sun, Zhenrong Zhang, Guowu Zhou, Dingrong Zhong,

<h4>Background</h4>Glomus tumors are uncommon and mostly benign mesenchymal neoplasms of the perivascular family. To date, only a few cases of glomus tumors occurring in the trachea have been reported. Tracheal glomus tumors simulated low-grade neuroendocrine tumors on clinical and histomorphological examination, so the differential diagnosis between these two entities is ... Read more >>

Ann Diagn Pathol (Annals of diagnostic pathology)
[2021, 55:151797]

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Physiological changes and transcript identification in Coreopsis tinctoria Nutt. in early stages of salt stress.

Hong Jiang, Zhiyuan Li, Xiumei Jiang, Yong Qin,

<i>Coreopsis tinctoria</i> Nutt. (<i>C. tinctoria</i>) is a special tea ingredient that adapts to certain salt stresses and shares the functions of chrysanthemum. With annual expansion of the cultivation area of <i>C. tinctoria</i> in Xinjiang (China), soil salinity may become a constraint for chrysanthemum cultivation. To investigate the response of C. ... Read more >>

PeerJ (PeerJ)
[2021, 9:e11888]

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Optimal allocation of CO2 emission quotas at the city level in Bohai Rim Economic Circle based on multi-objective decision approach.

Zhiyuan Li, Huadun Chen, Juan Wang, Tao Zhao,

As the most developed city circle in northern China, allocating CO<sub>2</sub> emission quotas at the Bohai Rim Economic Circle (BREC) city level is essential for developing specific abatement policies. Thus, with reflecting multi-principles (fairness, efficiency, sustainability, and feasibility), this paper formulates the CO<sub>2</sub> emission quota allocation among cities in BREC ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2021, 28(43):60798-60817]

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The Roles of Neuropeptide Y (Npy) and Peptide YY (Pyy) in Teleost Food Intake: A Mini Review.

Daniel Assan, Umar Farouk Mustapha, Huapu Chen, Zhiyuan Li, Yuhao Peng, Guangli Li,

Neuropeptide Y family (NPY) is a potent orexigenic peptide and pancreatic polypeptide family comprising neuropeptide Y (Npy), peptide YYa (Pyya), and peptide YYb (Pyyb), which was previously known as peptide Y (PY), and tetrapod pancreatic polypeptide (PP), but has not been exhaustively documented in fish. Nonetheless, <i>Npy</i> and <i>Pyy</i> to ... Read more >>

Life (Basel) (Life (Basel, Switzerland))
[2021, 11(6):]

Cited: 2 times

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