Full Text Journal Articles by
Author Zhikai Yang

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Association of Serum Adipokines and Resting Energy Expenditure in Patients with Chronic Kidney Disease

Nanzha Abi, Xiao Xu, Zhikai Yang, Tiantian Ma, Jie Dong,

<h4>Background: </h4> and aim: Metabolic disorders are prevalent in patients with chronic kidney disease (CKD) and may lead to protein energy wasting. Adipokines play a vital role in energy metabolism. We aimed to determine the relationship between adipokine levels and resting energy expenditure (REE) in patients with CKD. <h4>Methods: </h4>: ... Read more >>

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Trimethylamine-N-oxide (TMAO) and clinical outcomes in patients with end-stage kidney disease receiving peritoneal dialysis.

Dongyuan Chang, Xiao Xu, Zhikai Yang, Tiantian Ma, Jing Nie, Jie Dong,

<h4>Background</h4>Trimethylamine-N-oxide (TMAO) is a gut bacteria-derived metabolite of l-carnitine and choline. A high concentration of TMAO has been proven to relate to cardiovascular disease (CVD), all-cause mortality and chronic kidney disease progression. We aimed to investigate the relation between the value of serum TMAO and outcomes for peritoneal dialysis (PD) ... Read more >>

Perit Dial Int (Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis)
[2021, :8968608211051809]

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LncRNA TLR8-AS1 suppresses miR-34a maturation in hepatocellular carcinoma to suppress cell proliferation and migration.

Xin Shi, Hu Chen, Wei Wang, Bingzheng Yan, Zhikai Yang, Jingpo Zhang,

TLR8-AS1 has been characterized as an oncogenic lncRNA in ovarian cancer, while its role in hepatocellular carcinoma (HCC) is unknown. This study aimed to explore the role of TLR8-AS1 in HCC. TLR8-AS1 expression in HCC and paired non-tumor tissues from 62 HCC patients was determined by RT-qPCR. The prognostic value ... Read more >>

Mamm Genome (Mammalian genome : official journal of the International Mammalian Genome Society)
[2021, 32(6):530-536]

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Cefoperazone and sulbactam-related eosinophilic peritonitis: a case report and literature review.

Zi Wang, Zhiying Li, Suping Luo, Zhikai Yang, Ying Xing, Chengwei Pu, Jie Dong,

Eosinophilic peritonitis (EP) is a well-described complication of peritoneal dialysis that occurs because of an overreaction to constituents that are related to the catheter or tubing, peritoneal dialysate, pathogenic infection, or intraperitoneal drug use. EP caused by antibiotic use is rare. We present the case of a patient with cefoperazone ... Read more >>

J Int Med Res (The Journal of international medical research)
[2021, 49(6):3000605211025367]

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Identification of docetaxel-related biomarkers for prostate cancer.

Yun Peng, Shiqiang Dong, Zhikai Yang, Yuxuan Song, Jin Ding, Dingkun Hou, Lili Wang, Zheyu Zhang, Nan Li, Haitao Wang,

Prostate cancer (PCa) which was the second commonly diagnosed malignancy, contributed to the top fifth carcinoma death in men. Nevertheless, the main chemotherapeutic agent docetaxel came to failure due to chemoresistance. Recently, increasing evidence suggested the importance of tumour microenvironment (TME) in PCa. The present study aimed to explore the ... Read more >>

Andrologia (Andrologia)
[2021, 53(7):e14079]

Cited: 3 times

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Novel equation for estimating resting energy expenditure in patients with chronic kidney disease.

Xiao Xu, Zhikai Yang, Tiantian Ma, Ziqian Li, Yuan Chen, Yingdong Zheng, Jie Dong,

<h4>Background</h4>In chronic kidney disease (CKD), determining energy expenditure is the precondition for recommending energy intake in nutrition management.<h4>Objectives</h4>We aimed to develop and validate a resting energy expenditure (REE) equation for patients with CKD.<h4>Methods</h4>This cross-sectional study enrolled 300 patients with CKD (stages 3-5) according to inclusion and exclusion criteria. Stepwise linear ... Read more >>

Am J Clin Nutr (The American journal of clinical nutrition)
[2021, 113(6):1647-1656]

Cited: 1 time

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Genome-wide mediation analysis: bridging the divide between genotype and phenotype via transcriptomic data in maize

Zhikai Yang, Gen Xu, Qi Zhang, Toshihiro Obata, Jinliang Yang,

Mapping genotype to phenotype is an essential topic in genetics and genomics research. As the Omics data become increasingly available, genome-wide association study (GWAS) has been widely applied to establish the relationship between genotype and phenotype. However, signals detected by GWAS usually span broad genomic regions with many underneath candidate ... Read more >>

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Target localization during respiration motion based on LSTM: A pilot study on robotic puncture system.

Yuxiang Ma, Zhikai Yang, Wei Wu, Hongzhi Xie, Lixu Gu,

<h4>Background</h4>In the needle biopsy, the respiratory motion causes the displacement of thoracic-abdominal soft tissues, which brings great difficulty to accurate localization. Based on internal target motion and external marker motion, the existing methods need to establish a correlation model or a prediction model to compensate the respiratory movement, which can ... Read more >>

Int J Med Robot (The international journal of medical robotics + computer assisted surgery : MRCAS)
[2021, 17(3):e2247]

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The Peritoneal Dialysis Telemedicine-assisted Platform Cohort (PDTAP) Study: Design and methods.

Tiantian Ma, Zhikai Yang, Shaomei Li, Huaying Pei, Jinghong Zhao, Yi Li, Zibo Xiong, Yumei Liao, Zhanzheng Zhao, Jing Xiao, Ying Li, Qiongzhen Lin, Zhaoxia Zheng, Liping Duan, Gang Fu, Shanshan Guo, Wenbo Hu, Yulin Li, Fuyun Sun, Nan Zhao, Qin Wang, Tianrong Ji, Beiru Zhang, Rui Yu, Li Hao, Guiling Liu, Li Zuo, Huiping Zhao, Caili Wang, Lirong Deng, Hongyu Chen, Li Li, Yulan Shen, Yong Zhang, Lihua Wang, Yan Yan, Zhigang Ma, Yingping Li, Xianchao Zhang, Xuejian Wang, Yirong Liu, Xinying Gao, Zhonggao Xu, Li Zhang, Shutong Du, Cui Zhao, Xiaoli Chen, Hongyi Li, Yingli Yue, Shanshan Chen, Yingchun Ma, Yuanyuan Wei, Jingwei Zhou, Jie Lv, Yingdong Zheng, Sainan Zhu, Minghui Zhao, Jie Dong, ,

<h4>Objectives</h4>The primary objective of the Peritoneal Dialysis Telemedicine<b>-</b>assisted Platform Cohort (PDTAP) Study is to explore potential predictors and their effects on patient survival, technique survival, and the occurrence of infectious and noninfectious complications.<h4>Design</h4>The PDTAP study is a national-level cohort study in China. A newly developed PD telemedicine application provided a ... Read more >>

Perit Dial Int (Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis)
[2022, 42(1):75-82]

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Genomic selection to optimize doubled haploid-based hybrid breeding in maize

Jinlong Li, Dehe Cheng, Shuwei Guo, Zhikai Yang, Ming Chen, Chen Chen, Yanyan Jiao, Wei Li, Chenxu Liu, Yu Zhong, Xiaolong Qi, Jinliang Yang, Shaojiang Chen,

<h4>ABSTRACT</h4> Crop improvement, as a long-term endeavor, requires continuous innovations in technique from multiple perspectives. Doubled haploid (DH) technology for pure inbred production, which shaves years off of the conventional selfing approach, has been widely used for breeding. However, the final success rate of in vivo maternal DH production is ... Read more >>

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The cut-off values of handgrip strength and lean mass index for sarcopenia among patients on peritoneal dialysis.

Xiao Xu, Zhikai Yang, Tiantian Ma, Ziqian Li, Yuan Chen, Yingdong Zheng, Jie Dong,

<h4>Background</h4>Sarcopenia is common and contributes to a high risk of mortality among general population. There is no consensus regarding the cut-off values for sarcopenia in terms of mortality among chronic kidney disease patients. This study aimed to explore and validate cut-off points of handgrip strength (HGS) and lean mass index ... Read more >>

Nutr Metab (Lond) (Nutrition & metabolism)
[2020, 17:84]

Cited: 1 time

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Use of Peritoneal Dialysis in Acute Kidney Injury: How Far Away?

Zhikai Yang, Jie Dong, Li Yang,

Acute kidney injury (AKI) has become a worldwide public health problem, resulting in a high risk of mortality and progression to chronic kidney disease. Peritoneal dialysis (PD) can be an effective renal support for AKI, especially in regions where medical resources are limited, but actually underused. In this article, the ... Read more >>

Semin Nephrol (Seminars in nephrology)
[2020, 40(5):506-515]

Cited: 1 time

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Operational considerations for peritoneal dialysis management during the COVID-19 pandemic.

Zhikai Yang, Jie Dong,

<h4>Background</h4>Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease caused by a novel coronavirus-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is spread from human to human and has resulted in a global pandemic, posing a disastrous public health risk worldwide. Patients with chronic kidney disease, especially those on dialysis, ... Read more >>

Clin Kidney J (Clinical kidney journal)
[2020, 13(3):322-327]

Cited: 1 time

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Acute Kidney Injury Relevant to Tubulointerstitial Nephritis with Late-Onset Uveitis Superimposed by Thrombotic Microangiopathy: A Case Report and Review of the Literature.

Youlu Zhao, Junwen Huang, Tao Su, Zhikai Yang, Xizi Zheng, Liu Yang, Xujie Zhou, Xiaojuan Yu, Hui Wang, Suxia Wang, Gang Liu, Li Yang,

<h4>Background</h4>The syndrome of tubulointerstitial nephritis and uveitis (TINU) is an uncommon and multisystemic autoimmune disorder. This review reports a rare case of TINU being superimposed on thrombotic microangiopathy (TMA) and, by comparing with the available literature, also summarizes the clinical features, associated conditions, treatment, and outcome of patients with TINU.<h4>Summary</h4>Herein, ... Read more >>

Kidney Dis (Basel) (Kidney diseases (Basel, Switzerland))
[2020, 6(6):414-421]

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Prevention of peritoneal dialysis-related peritonitis by regular patient retraining via technique inspection or oral education: a randomized controlled trial.

Ying Xu, Yuhui Zhang, Bin Yang, Suping Luo, Zhikai Yang, David W Johnson, Jie Dong,

BACKGROUND:There has been little research on strategies for prevention of peritoneal dialysis (PD)-related peritonitis. We explored whether regular retraining on bag exchanges (via two methods: technique inspection and oral education) every other month could help reduce the risk of peritonitis in PD patients through a randomized controlled trial (RCT). METHOD:This ... Read more >>

Nephrol Dial Transplant (Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association)
[2020, 35(4):676-686]

Cited: 1 time

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Eosinophilic peritonitis and nephrotic syndrome in Kimura's disease: a case report and literature review : Eosinophilic peritonitis in Kimura's disease.

Bingxin Yu, Zhikai Yang, Di Song, Zi Wang, Damin Xu, Suxia Wang, Lin Nong, Fude Zhou, Jie Dong,

<h4>Background</h4>Eosinophilic peritonitis is a relatively rare entity. Kimura's disease is a rare chronic inflammatory disorder of unknown etiology, characterized by subcutaneous nodules mainly in the head and neck region, regional lymphadenopathy and occasional involvement of kidney. There is currently no report of eosinophilic peritonitis in Kimura's disease.<h4>Case presentation</h4>A 44-year-old Chinese ... Read more >>

BMC Nephrol (BMC nephrology)
[2020, 21(1):138]

Cited: 1 time

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Pramipexole in peritoneal dialysis patients with restless legs syndrome (RLS): a protocol for a multicentre double-blind randomised controlled trial.

Tian-Tian Ma, Zhikai Yang, Sainan Zhu, Jing-Hong Zhao, Yi Li, Fu-Yun Sun, Nan Zhao, Zu-Ying Xiong, Zi-Bo Xiong, Jie Dong,

<h4>Introduction</h4>Restless legs syndrome (RLS) is a common neurological sensorimotor disorder among patients with end stage renal disease. This clinical trial aimed to provide evidence on the efficacy and safety of pramipexole in patients with uremic RLS receiving peritoneal dialysis (PD).<h4>Methods and analysis</h4>This is a 12-week, multicentre, randomised, double-blind, placebo-controlled clinical ... Read more >>

BMJ Open (BMJ open)
[2020, 10(2):e033815]

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The cut-off values of handgrip strength and lean mass index for sarcopenia among patients on peritoneal dialysis

Xiao Xu, Zhikai Yang, Tiantian Ma, Ziqian Li, Yuan Chen, Yingdong Zheng, Jie Dong,

Background Sarcopenia is common and contributes to a high risk of mortality among general population. There is no consensus regarding the cut-off values for sarcopenia in terms of mortality among chronic kidney disease patients. This study aimed to explore and validate cut-off points of handgrip strength (HGS) and lean mass ... Read more >>

Nutr Metab (Lond) (Nutrition & metabolism)
[2020, 17:]

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The effects of oral vitamin D supplementation on the prevention of peritoneal dialysis-related peritonitis: study protocol for a randomized controlled clinical trial

Yuhui Zhang, Xiao Xu, Haichen Pi, Zhikai Yang, David Johnson, Jie Dong,

<h4>Background: </h4> Vitamin D deficiency has been shown to be closely associated with peritoneal dialysis (PD)-related peritonitis. The aim of this study is to examine the feasibility of conducting a large, powered randomized controlled trial to determine the effects of vitamin D supplementation on the risk of PD-related peritonitis in ... Read more >>

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Sleep Disorders and Cognitive Impairment in Peritoneal Dialysis: A Multicenter Prospective Cohort Study.

Youlu Zhao, Yuhui Zhang, Zhikai Yang, Jinwei Wang, Zuying Xiong, Jinlan Liao, Li Hao, Guiling Liu, Yeping Ren, Qin Wang, Liping Duan, Zhaoxia Zheng, Jie Dong,

<h4>Background</h4>Patients with chronic kidney disease experience a high burden of sleep disorders, and there are associations between sleep disorders and cognitive impairment.<h4>Objectives</h4>Based on our previous cross-sectional survey on cognitive impairment in peritoneal dialysis, we further explored the relationship between sleep disorders and cognitive impairment, and predictors for declining cognitive function.<h4>Method</h4>We ... Read more >>

Kidney Blood Press Res (Kidney & blood pressure research)
[2019, 44(5):1115-1127]

Cited: 7 times

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Effects of tea polyphenols on the structural and physicochemical properties of high-hydrostatic-pressure-gelatinized rice starch

Jingjing Du, Xianfeng Du, Xiaona Wang, Xiaonan Xu, Zhikai Yang,

Effects of tea polyphenols (TP) on the structural and physicochemical properties of rice starch were evaluated under a 30 min high hydrostatic pressure (HHP) treatment (200–600 MPa). The results of differential scanning calorimetry (DSC) indicated a reduction in the gelatinization temperatures and the gelatinization enthalpy of rice starch/tea polyphenols (RS/TP) ... Read more >>

(Food hydrocolloids.)
[2019, 91:256-262]

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Improvement of stability of blueberry anthocyanins by carboxymethyl starch/xanthan gum combinations microencapsulation

Xuran Cai, Xianfeng Du, Daomei Cui, Xiaona Wang, Zhikai Yang, Guilan Zhu,

The study was to improve the stability of blueberry anthocyanins (ANS) by encapsulating it with carboxymethyl starch (CMS)/xanthan gum (XG) combinations of five ratios (CMS/XG: 30/1, 60/1, 90/1, 120/1, 150/1, w/w). The results revealed that all the microcapsules presented high encapsulation efficiency. Fluorescence microscopy showed that ANS distributed homogenously through ... Read more >>

(Food hydrocolloids.)
[2019, 91:238-245]

Cited: 2 times

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Effect of ultra-high pressure on quality characteristics of parboiled rice

Xiaonan Xu, Weilong Yan, Zhikai Yang, Xiaona Wang, Yu Xiao, Xianfeng Du,

Quality characteristics of parboiled rice pre-treated by ultra-high pressures (UHP, 100–600 MPa) were investigated in this study. The LF-NMR results and morphologies of parboiled rice grain showed that UHP treatment promoted uniform distribution of water in rice grain and effectively eliminated “white-core” grain. The total colour difference (ΔE*) increased with ... Read more >>

J Cereal Sci (Journal of cereal science)
[2019, 87:117-123]

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Intraperitoneal Vancomycin Plus Either Oral Moxifloxacin or Intraperitoneal Ceftazidime for the Treatment of Peritoneal Dialysis-Related Peritonitis: A Randomized Controlled Pilot Study.

Rong Xu, Zhikai Yang, Zhen Qu, Huan Wang, Xue Tian, David W Johnson, Jie Dong,

<h4>Background</h4>Intraperitoneal administration of antibiotics is recommended as a first treatment for managing peritoneal dialysis (PD)-related peritonitis. However, the efficacy of oral administration of quinolones has not been well studied.<h4>Study design</h4>Randomized controlled pilot study.<h4>Setting & participants</h4>80 eligible patients with PD-related peritonitis from Peking University First Hospital (40 in each arm).<h4>Intervention</h4>Intraperitoneal vancomycin, ... Read more >>

Am J Kidney Dis (American journal of kidney diseases : the official journal of the National Kidney Foundation)
[2017, 70(1):30-37]

Cited: 2 times

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Reciprocal genomic evolution in the ant-fungus agricultural symbiosis.

Sanne Nygaard, Haofu Hu, Cai Li, Morten Schiøtt, Zhensheng Chen, Zhikai Yang, Qiaolin Xie, Chunyu Ma, Yuan Deng, Rebecca B Dikow, Christian Rabeling, David R Nash, William T Wcislo, Seán G Brady, Ted R Schultz, Guojie Zhang, Jacobus J Boomsma,

The attine ant-fungus agricultural symbiosis evolved over tens of millions of years, producing complex societies with industrial-scale farming analogous to that of humans. Here we document reciprocal shifts in the genomes and transcriptomes of seven fungus-farming ant species and their fungal cultivars. We show that ant subsistence farming probably originated ... Read more >>

Nat Commun (Nature communications)
[2016, 7:12233]

Cited: 42 times

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