Full Text Journal Articles by
Author Zhi Heng Rao

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Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.

Shu-Jie Wu, Zhong-Hao Lin, Yuan-Zheng Lin, Zhi-Heng Rao, Jia-Feng Lin, Lian-Pin Wu, Lei Li,

Background:Persistent myocardial ischemia post-myocardial infarction can lead to fatal ventricular arrhythmias such as ventricular tachycardia and fibrillation, both of which carry high mortality rates. Dexmedetomidine (Dex) is a highly selective α2-agonist used in surgery for congenital cardiac disease because of its antiarrhythmic properties. Dex has previously been reported to prevent ... Read more >>

Front Physiol (Frontiers in physiology)
[2020, 11:33]

Cited: 0 times

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Alteration of Cholinergic Anti-Inflammatory Pathway in Rat With Ischemic Cardiomyopathy-Modified Electrophysiological Function of Heart.

Shu-Jie Wu, Yue-Chun Li, Zhe-Wei Shi, Zhong-Hao Lin, Zhi-Heng Rao, Si-Chao Tai, Mao-Ping Chu, Lei Li, Jia-Feng Lin,

With chronic ischemia after myocardial infarction, the resulting scar tissue result in electrical and structural remodeling vulnerable to an arrhythmogenic substrate. The cholinergic anti-inflammatory pathway elicited by vagal nerve via α7 nicotinic acetylcholine receptors (α7-nAChR) can modulate local and systemic inflammatory responses. Here, we aimed to clarify a novel mechanism ... Read more >>

J Am Heart Assoc (Journal of the American Heart Association)
[2017, 6(9):]

Cited: 4 times

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