Full Text Journal Articles by
Author Zhaoxiong Chen

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Urinary Molecular Pathology for Patients with Newly Diagnosed Urothelial Bladder Cancer.

Ruiyun Zhang, Jingyu Zang, Feng Xie, Yue Zhang, Yiqiu Wang, Ying Jing, Yi Zhang, Zhaoxiong Chen, Akezhouli Shahatiaili, Mei-Chun Cai, Zhixin Zhao, Pan Du, Shidong Jia, Guanglei Zhuang, Haige Chen,

<h4>Purpose</h4>Next-generation sequencing (NGS)-based profiling of both urinary tumor DNA (utDNA) and circulating tumor DNA (ctDNA) shows promise for noninvasive detection and surveillance of urothelial bladder cancer (UBC). However, the analytic performance of these assays remains undefined in the real-world setting. Here, we sought to evaluate the concordance between tumor DNA ... Read more >>

J Urol (The Journal of urology)
[2021, :101097JU0000000000001878]

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Microbial process-oriented understanding of stimulation of soil N2O emission following the input of organic materials.

Zhaoxiong Chen, Xiaoshun Tu, Han Meng, Chen Chen, Yuejun Chen, Ahmed S Elrys, Yi Cheng, Jinbo Zhang, Zucong Cai,

Although crop residue return increases upland soil emissions of nitrous oxide (N<sub>2</sub>O), a potent greenhouse gas, the mechanisms responsible for the increase remain unclear. Here, we investigate N<sub>2</sub>O emission pathways, gross nitrogen (N)-cycling rates, and associated N-cycling gene abundances in an upland soil following the addition of various organic material ... Read more >>

Environ Pollut (Environmental pollution (Barking, Essex : 1987))
[2021, 284:117176]

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Dynamic Stabilization Adjacent to Fusion versus Posterior Lumbar Interbody Fusion for the Treatment of Lumbar Degenerative Disease: A Meta-Analysis.

Xiangyao Sun, Zhaoxiong Chen, Siyuan Sun, Wei Wang, Tongtong Zhang, Chao Kong, Shibao Lu,

This study evaluated differences in outcome variables between dynamic stabilization adjacent to fusion (DATF) and posterior lumbar interbody fusion (PLIF) for the treatment of lumbar degenerative disease. A systematic review of PubMed, EMBASE, and Cochrane was performed. The variables of interest included clinical adjacent segment pathologies (CASPs), radiological adjacent segment ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:9309134]

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Intervertebral disc degeneration in mice with type II diabetes induced by leptin receptor deficiency.

Xinhua Li, Xiaoming Liu, Yiru Wang, Fuming Cao, Zhaoxiong Chen, Zhouyang Hu, Bin Yu, Hang Feng, Zhaoyu Ba, Tao Liu, Haoxi Li, Bei Jiang, Yufeng Huang, Lijun Li, Desheng Wu,

BACKGROUND:The leptin receptor-deficient knockout (db/db) mouse is a well-established model for studying type II diabetes mellitus (T2DM). T2DM is an important risk factor of intervertebral disc degeneration (IVDD). Although the relationship between type I diabetes and IVDD has been reported by many studies, few studies have reported the effects of ... Read more >>

BMC Musculoskelet Disord (BMC musculoskeletal disorders)
[2020, 21(1):77]

Cited: 3 times

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Accurate loop calling for 3D genomic data with cLoops.

Yaqiang Cao, Zhaoxiong Chen, Xingwei Chen, Daosheng Ai, Guoyu Chen, Joseph McDermott, Yi Huang, Xiaoxiao Guo, Jing-Dong J Han,

<h4>Motivation</h4>Sequencing-based 3D genome mapping technologies can identify loops formed by interactions between regulatory elements hundreds of kilobases apart. Existing loop-calling tools are mostly restricted to a single data type, with accuracy dependent on a predefined resolution contact matrix or called peaks, and can have prohibitive hardware costs.<h4>Results</h4>Here, we introduce cLoops ... Read more >>

Bioinformatics (Bioinformatics (Oxford, England))
[2020, 36(3):666-675]

Cited: 9 times

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Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions.

Yaqiang Cao, Guoyu Chen, Gang Wu, Xiaoli Zhang, Joseph McDermott, Xingwei Chen, Chi Xu, Quanlong Jiang, Zhaoxiong Chen, Yingying Zeng, Daosheng Ai, Yi Huang, Jing-Dong J Han,

A few families of transposable elements (TEs) have been shown to evolve into <i>cis</i>-regulatory elements (CREs). Here, to extend these studies to all classes of TEs in the human genome, we identified widespread enhancer-like repeats (ELRs) and find that ELRs reliably mark cell identities, are enriched for lineage-specific master transcription ... Read more >>

Genome Res (Genome research)
[2019, 29(1):40-52]

Cited: 11 times

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Accurate loop calling for 3D genomic data with cLoops

Yaqiang Cao, Xingwei Chen, Daosheng Ai, Zhaoxiong Chen, Guoyu Chen, Joseph McDermott, Yi Huang, Jing-Dong Han,

Sequencing-based 3D genome mapping technologies can identify loops formed by interactions between regulatory elements hundreds of kilobases apart. Existing loop-calling tools are mostly restricted to a single data type, with accuracy dependent on a pre-defined resolution contact matrix or called peaks, and can have prohibitive hardware costs. Here we introduce ... Read more >>

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Morphometry evaluations of cervical osseous endplates based on three dimensional reconstructions.

Hang Feng, Haoxi Li, Zhaoyu Ba, Zhaoxiong Chen, Xinhua Li, Desheng Wu, Desheng Wu,

<h4>Purpose</h4>Accurate and comprehensive data on cervical endplates is essential for developing and improving cervical devices. However, current literature on vertebral disc geometry is scarce or not suitable. The aim of this study was to obtain quantitative parameters of cervical endplates and provide morphometric references for designing cervical devices.<h4>Methods</h4>In this study, ... Read more >>

Int Orthop (International orthopaedics)
[2019, 43(6):1521-1528]

Cited: 1 time

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A retrospective study: Does cigarette smoking induce cervical disc degeneration?

Zhaoxiong Chen, Xinhua Li, Fumin Pan, Desheng Wu, Haoxi Li,

<h4>Objective</h4>To investigate cigarette smoking's relevance with cervical disc degeneration.<h4>Methods</h4>We randomly selected 320 patients who came to our spine disease department outpatient clinic with chief complaint of neck-shoulder pain during June 2014-June 2016. According to the detailed smoking history, these patients were divided into 3 different groups, which were active smoker ... Read more >>

Int J Surg (International journal of surgery (London, England))
[2018, 53:269-273]

Cited: 2 times

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Prioritized cervical or lumbar surgery for coexisting cervical and lumbar stenosis: Prognostic analysis of 222 case.

Haoxi Li, Zhaoxiong Chen, Xinhua Li, Tao Liu, Bin Shen, Yufeng Huang, Desheng Wu,

<h4>Background context</h4>Single-stage surgery is usually applied to improving the symptoms of coexisting cervical and lumbar stenosis. In most cases, patients' willingness, surgery affordability, surgical trauma, surgical complications and patients' tolerance to surgery all limit the application of single-stage surgery. For patients who cannot receive single-stage surgery, we hope that we ... Read more >>

Int J Surg (International journal of surgery (London, England))
[2017, 44:344-349]

Cited: 2 times

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Emergency 1-stage anterior approach for cervical spine infection complicated by epidural abscess.

Haoxi Li, Zhaoxiong Chen, Zhiyao Yong, Xinhua Li, Yufeng Huang, Desheng Wu,

It was a retrospective analysis.The aim of the study was to explore the safety and reliability of emergency 1-stage radical debridement and reconstruction using titanium mesh filled with autologous bone for patients with cervical spine infection complicated by epidural abscess.At present, cervical spine infection complicated by epidural abscess is known ... Read more >>

Medicine (Baltimore) (Medicine)
[2017, 96(26):e7301]

Cited: 1 time

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Literature mining of protein phosphorylation using dependency parse trees.

Mang Wang, Hong Xia, Dongdong Sun, Zhaoxiong Chen, Minghui Wang, Ao Li,

As one of the most common post-translational modifications (PTMs), protein phosphorylation plays an important role in various biological processes, such as signaling transduction, cellular metabolism, differentiation, growth, regulation and apoptosis. Protein phosphorylation is of great value not only in illustrating the underlying molecular mechanisms but also in treatment of diseases ... Read more >>

Methods (Methods (San Diego, Calif.))
[2014, 67(3):386-393]

Cited: 1 time

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Aquarium

ZHAOXIONG CHEN,

The utility model relates to an aquarium, which comprises a body, a cover, a filter and a lighting device. The aquarium is characterized in that the filter and the lighting device are arranged in a top board the filter consists of a water pump and a filter tank a filter ... Read more >>

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