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Monitoring bronchoalveolar lavage with electrical impedance tomography: first experience in a patient with COVID-19.

Yingyun Fu, Rongrong Zou, Shouhong Wang, Junmin Wen, Lei Rong, Ming Tang, Baojun Yu, Fulan Cen, Zhanqi Zhao, Inez Frerichs, Andy Adler, Yingxia Liu, Lei Liu,

Patients with the novel coronavirus disease (COVID-19) often have airways secretions that severely compromise ventilation. This study investigates electrical impedance tomography (EIT) monitoring of a therapeutic bronchoalveolar lavage (BAL) in a patient with COVID-19. A patient with COVID-19 developed acute respiratory distress syndrome requiring mechanical ventilation. He received regional BAL ... Read more >>

Physiol Meas (Physiological measurement)
[2020, :]

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Detection of Acute Pulmonary Embolism by Electrical Impedance Tomography and Saline Bolus Injection.

Huaiwu He, Yun Long, Inéz Frerichs, Zhanqi Zhao,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, :]

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Bedside Evaluation of Pulmonary Embolism by Saline Contrast Electrical Impedance Tomography Method:A Prospective Observational Study.

Huaiwu He, Yi Chi, Yun Long, Siyi Yuan, Rui Zhang, Inéz Frerichs, Knut Möller, Feng Fu, Zhanqi Zhao,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, :]

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Titration of extra-PEEP against intrinsic-PEEP in severe asthma by electrical impedance tomography: A case report and literature review.

Huaiwu He, Siyi Yuan, Chi Yi, Yun Long, Rui Zhang, Zhanqi Zhao,

RATIONALE:The use of extra-positive end-expiratory pressure (PEEP) at a level of 80% intrinsic-PEEP (iPEEP) to improve ventilation in severe asthma patients with control ventilation remains controversial. Electrical impedance tomography (EIT) may provide regional information for determining the optimal extra-PEEP to overcome gas trapping and distribution. Moreover, the experience of using ... Read more >>

Medicine (Madr) (Medicine)
[2020, 99(26):e20891]

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COVID-19 pneumonia: phenotype assessment requires bedside tools.

Zhanqi Zhao, Wan-Hsuan Kung, Hou-Tai Chang, Yeong-Long Hsu, Inéz Frerichs,

Crit Care (Critical care (London, England))
[2020, 24(1):272]

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Effect of postextubation high-flow nasal cannula therapy on lung recruitment and overdistension in high-risk patient.

Rui Zhang, Huaiwu He, Long Yun, Xiang Zhou, Xu Wang, Yi Chi, Siyi Yuan, Zhanqi Zhao,

BACKGROUND:Postextubation high-flow nasal cannula (HFNC) is used as a support therapy in high-risk patients in ICU. This study aimed to determine the effects of HFNC therapy on lung recruitment and overdistension assessed by electrical impedance tomography (EIT). METHODS:Twenty-four patients who received HFNC within 24 h after extubation were prospectively enrolled in ... Read more >>

Crit Care (Critical care (London, England))
[2020, 24(1):82]

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Optimal mean airway pressure during high-frequency oscillatory ventilation in an experimental model of acute respiratory distress syndrome: EIT-based method.

Songqiao Liu, Zhanqi Zhao, Li Tan, Lihui Wang, Knut Möller, Inéz Frerichs, Tao Yu, Yingzi Huang, Chun Pan, Yi Yang, Haibo Qiu,

BACKGROUND:High-frequency oscillatory ventilation (HFOV) may theoretically provide lung protective ventilation. The negative clinical results may be due to inadequate mean airway pressure (mPaw) settings in HFOV. Our objective was to evaluate the air distribution, ventilatory and hemodynamic effects of individual mPaw titration during HFOV in ARDS animal based on oxygenation ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2020, 10(1):31]

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Thoracic electrical impedance tomography in Chinese hospitals: a review of clinical research and daily applications.

Zhanqi Zhao, Feng Fu, Inéz Frerichs,

Chinese scientists and researchers have a long history with electrical impedance tomography (EIT), which can be dated back to the 1980s. No commercial EIT devices for chest imaging were available until the year 2014 when the first device received its approval from the China Food and Drug Administration. Ever since ... Read more >>

Physiol Meas (Physiological measurement)
[2020, 41(4):04TR01]

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The influence of an electrical impedance tomography belt on lung function determined by spirometry in sitting position.

Na Zhang, Hongying Jiang, Chenxi Zhang, Qing Li, Yi Li, Bin Zhang, Jia Deng, Guangyu Niu, Bo Yang, Inez Frerichs, Knut Moeller, Feng Fu, Zhanqi Zhao,

OBJECTIVE:The aim of the study was to examine whether an electrical impedance tomography (EIT) electrode belt changed the lung function in healthy volunteers and patients with respiratory muscle weakness (RMW) and chronic obstructive pulmonary disease (COPD). APPROACH:In total, thirty subjects were included (10 healthy volunteers, 10 subjects with RMW, maximum ... Read more >>

Physiol Meas (Physiological measurement)
[2020, 41(4):044002]

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Regional air trapping in acute exacerbation of obstructive lung diseases measured with electrical impedance tomography: a feasibility study.

Zhanqi Zhao, Mei-Yun Chang, Inéz Frerichs, Jia-Hao Zhang, Hou-Tai Chang, Chien-Hung Gow, Knut Möller,

BACKGROUND:Since bronchial abnormalities often exhibit spatial non-uniformity which may be not correctly assessed by conventional global lung function measures, regional information may help to characterize the disease progress. We hypothesized that regional air trapping during mechanical ventilation could be characterized by regional end-expiratory flow (EEF) derived from electrical impedance tomography ... Read more >>

Minerva Anestesiol (Minerva anestesiologica)
[2020, 86(2):172-180]

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Simple Electrical Impedance Tomography Measures for the Assessment of Ventilation Distribution.

Inéz Frerichs, Zhanqi Zhao, Tobias Becher,

Am. J. Respir. Crit. Care Med. (American journal of respiratory and critical care medicine)
[2020, 201(3):386-388]

Cited: 1 time

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PEEP guided by electrical impedance tomography during one-lung ventilation in elderly patients undergoing thoracoscopic surgery.

Kun Liu, Chengya Huang, Meiying Xu, Jingxiang Wu, Inez Frerichs, Knut Moeller, Zhanqi Zhao,

Background:To examine the influence of positive end-expiratory pressure (PEEP) settings on lung mechanics and oxygenation in elderly patients undergoing thoracoscopic surgery. Methods:One hundred patients aged >65 years were randomly allocated into either the PEEP5 or the electrical impedance tomography (EIT) group (PEEPEIT). Each group underwent volume-controlled ventilation (tidal volume 6 ... Read more >>

Ann Transl Med (Annals of translational medicine)
[2019, 7(23):757]

Cited: 1 time

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Oxygen Therapy Delivery and Body Position Effects Measured With Electrical Impedance Tomography.

Zhiyong Yuan, Xiaoning Han, Lisha Wang, Ping Xue, Yunbo Sun, Inéz Frerichs, Knut Möller, Jinyan Xing, Zhanqi Zhao,

BACKGROUND:The aim of this prospective randomized crossover study was to compare the short-term effects of high-flow nasal cannula (HFNC) therapy and a 45° head-up tilt to the short-term effects of conventional oxygen (O2) therapy in post-abdominal surgery patients. METHODS:A total of 18 subjects who were successfully weaned from ventilator support ... Read more >>

Respir Care (Respiratory care)
[2020, 65(3):281-287]

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Respiratory muscle endurance training with normocapnic hyperpnoea for patients with chronic spinal cord injury: A pilot short-term randomized controlled trial.

Jianing Xi, Hongying Jiang, Na Zhang, Jianjun Wang, Bin Zhang, Hongli Cao, Bo Yang, Inez Frerichs, Knut Möller, Zhanqi Zhao,

OBJECTIVE:To investigate the effects of normocapnic hyperpnoea training on pulmonary function and patient-reported outcomes in chronic spinal cord injury. DESIGN:Single-centre randomized controlled trial. PATIENTS:Eighteen patients with spinal cord injury > 24 months post-injury and without regular respiratory muscle training prior to the study were included prospectively. METHODS:Patients were randomly assigned to ... Read more >>

J Rehabil Med (Journal of rehabilitation medicine)
[2019, 51(8):616-620]

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Electrical impedance tomography for chest imaging in acute respiratory failure.

Inéz Frerichs, Zhanqi Zhao,

Eur. Respir. J. (The European respiratory journal)
[2019, 54(4):]

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The incidence and interpretation of large differences in EIT-based measures for PEEP titration in ARDS patients.

Zhanqi Zhao, Li-Chung Lee, Mei-Yun Chang, Inez Frerichs, Hou-Tai Chang, Chien-Hung Gow, Yeong-Long Hsu, Knut Möller,

Positive end-expiratory pressure (PEEP) can be titrated by electrical impedance tomography (EIT). The aim of the present study was to examine the performance of different EIT measures during PEEP trials with the aim of identifying "optimum" PEEP and to provide possible interpretations of largely diverging results. After recruitment (maximum plateau ... Read more >>

J Clin Monit Comput (Journal of Clinical Monitoring and Computing)
[2019, :]

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Regional lung function in nonsmokers and asymptomatic current and former smokers.

Barbara Vogt, Kathinka Deuß, Victoria Hennig, Zhanqi Zhao, Ingmar Lautenschläger, Norbert Weiler, Inéz Frerichs,

Electrical impedance tomography (EIT) is able to detect rapid lung volume changes during breathing. The aim of our observational study was to characterise the heterogeneity of regional ventilation distribution in lung-healthy adults by EIT and to detect the possible impact of tobacco consumption. A total of 219 nonsmokers, asymptomatic ex-smokers ... Read more >>

ERJ Open Res (ERJ open research)
[2019, 5(3):]

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Comparison of Combined Bipolar Radiofrequency Impedance-Controlled Endometrial Ablation with Levonorgestrel Intrauterine System versus Bipolar Radiofrequency Endometrial Ablation Alone in Women with Abnormal Uterine Bleeding.

Hui Zhao, Baojun Yang, Limin Feng, Haixia Li, Hongyu Shang, Zhanqi Zhao, Yinmei Dai,

STUDY OBJECTIVE:This study aims to evaluate the efficacy of the combination of bipolar radiofrequency impedance-controlled endometrial ablation (NovaSure; Hologic Inc., Bedford, MA) and levonorgestrel intrauterine system (LNG-IUS; Mirena; Schering AG, Berlin, Germany) placement in comparison with NovaSure endometrial ablation alone in patients with abnormal uterine bleeding (AUB). DESIGN:A propensity score ... Read more >>

J Minim Invasive Gynecol (Journal of minimally invasive gynecology)
[2020, 27(3):774-780]

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Detection of pulmonary oedema by electrical impedance tomography: validation of previously proposed approaches in a clinical setting.

Zhanqi Zhao, Hongli He, Jingying Luo, Andy Adler, Xiaoqin Zhang, Rongan Liu, Yunping Lan, Sen Lu, Xiaoxiu Luo, Yu Lei, Inez Frerichs, Xiaobo Huang, Knut Möller,

OBJECTIVE:The aim of the present study was to evaluate two previously proposed approaches based on electrical impedance tomography (EIT) to assess pulmonary oedema at the bedside. APPROACH:Fourteen patients with acute respiratory distress syndrome were included and examined prospectively. Patients were rotated laterally along their longitudinal axis from supine to 45-degree ... Read more >>

Physiol Meas (Physiological measurement)
[2019, 40(5):054008]

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A Review of Electrical Impedance Tomography in Lung Applications: Theory and Algorithms for Absolute Images.

Thiago de Castro Martins, André Kubagawa Sato, Fernando Silva de Moura, Erick Dario León Bueno de Camargo, Olavo Luppi Silva, Talles Batista Rattis Santos, Zhanqi Zhao, Knut Möeller, Marcelo Brito Passos Amato, Jennifer L Mueller, Raul Gonzalez Lima, Marcos de Sales Guerra Tsuzuki,

Electrical Impedance Tomography (EIT) is under fast development, the present paper is a review of some procedures that are contributing to improve spatial resolution and material properties accuracy, admitivitty or impeditivity accuracy. A review of EIT medical applications is presented and they were classified into three broad categories: ARDS patients, ... Read more >>

Annu Rev Control (Annual reviews in control)
[2019, 48:442-471]

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Comparison of electrical impedance tomography and intracranial pressure during dehydration treatment of cerebral edema.

Bin Yang, Bing Li, Canhua Xu, Shijie Hu, Meng Dai, Junying Xia, Peng Luo, Xuetao Shi, Zhanqi Zhao, Xiuzhen Dong, Zhou Fei, Feng Fu,

Cerebral edema after brain injury can lead to brain damage and death if diagnosis and treatment are delayed. This study investigates the feasibility of employing electrical impedance tomography (EIT) as a non-invasive imaging tool for monitoring the development of cerebral edema, in which impedance imaging of the brain related to ... Read more >>

Neuroimage Clin (NeuroImage. Clinical)
[2019, 23:101909]

Cited: 2 times

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Inspiratory muscle training can be monitored by electrical impedance tomography.

Zhanqi Zhao, Inez Frerichs, Mei-Yun Chang, Knut Möller,

Aust Crit Care (Australian critical care : official journal of the Confederation of Australian Critical Care Nurses)
[2019, 32(2):79-80]

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The calculation of mechanical power is not suitable for intra-patient monitoring under pressure-controlled ventilation.

Zhanqi Zhao, Inez Frerichs, Huaiwu He, Yun Long, Knut Möller, Ary Serpa Neto, Marcus J Schultz,

Intensive Care Med (Intensive Care Medicine)
[2019, 45(5):749-750]

Cited: 1 time

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Positive end-expiratory pressure titration with electrical impedance tomography and pressure-volume curve in severe acute respiratory distress syndrome.

Zhanqi Zhao, Mei-Ying Chang, Mei-Yun Chang, Chien-Hung Gow, Jia-Hao Zhang, Yeong-Long Hsu, Inez Frerichs, Hou-Tai Chang, Knut Möller,

BACKGROUND:The study objective was to compare titration of positive end-expiratory pressure (PEEP) with electrical impedance tomography (EIT) and with ventilator-embedded pressure-volume loop in severe acute respiratory distress syndrome (ARDS). METHODS:We have designed a prospective study with historical control group. Twenty-four severe ARDS patients (arterial oxygen partial pressure to fractional inspired ... Read more >>

Ann Intensive Care (Annals of intensive care)
[2019, 9(1):7]

Cited: 2 times

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Electrical Impedance Changes at Different Phases of Cerebral Edema in Rats with Ischemic Brain Injury.

Jiali Song, Rongqing Chen, Lin Yang, Ge Zhang, Weichen Li, Zhanqi Zhao, Canhua Xu, Xiuzhen Dong, Feng Fu, Feng Fu,

Cerebral edema contributes significantly to the morbidity and mortality associated with many common neurologic conditions. Clinically, a diagnostic tool that can be used to monitor cerebral edema in real-time and differentiate between different types of cerebral edema is urgently needed. Because there are differences in electrical impedance between normal cortical ... Read more >>

Biomed Res Int (BioMed research international)
[2018, 2018:9765174]

Cited: 1 time

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