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Strontium-substituted hydroxyapatite grown on graphene oxide nanosheet-reinforced chitosan scaffold to promote bone regeneration.

Tingting Wu, Binglin Li, Wanshun Wang, Lingling Chen, Zhan Li, Ming Wang, Zhengang Zha, Zefeng Lin, Hong Xia, Tao Zhang,

The strontium-substituted hydroxyapatite (SrHA) is a commonly used material in bone regeneration for its good osteoconductivity and high alkaline phosphatase (ALP) activity. Scaffolds used in bone defects require a high compressive modulus. However, the SrHA nanoparticle-doped scaffold cannot properly fit the required mechanical properties. Therefore, a lot of effort has ... Read more >>

Biomater Sci (Biomaterials science)
[2020, 8(16):4603-4615]

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A phenylenediamine-based carbon dot-modified silica stationary phase for hydrophilic interaction chromatography.

Yali Yang, Haijuan Zhang, Jia Chen, Zhan Li, Liang Zhao, Hongdeng Qiu,

Red emitting carbon dots derived from p-phenylenediamine (PPDCDs) were successfully prepared and grafted onto the surface of silica spheres, which served as a new stationary phase (Sil-PPDCDs) for liquid chromatography with excellent hydrophilic selectivity. Various hydrophilic analytes including nucleosides and bases, amino acids, saccharides and ginsenosides can be well separated ... Read more >>

Analyst (The Analyst)
[2020, 145(3):1056-1061]

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The ATR-WEE1 kinase module inhibits the MAC complex to regulate replication stress response.

Lili Wang, Li Zhan, Yan Zhao, Yongchi Huang, Chong Wu, Ting Pan, Qi Qin, Yiren Xu, Zhiping Deng, Jing Li, Honghong Hu, Shaowu Xue, Shunping Yan,

DNA damage response is a fundamental mechanism to maintain genome stability. The ATR-WEE1 kinase module plays a central role in response to replication stress. Although the ATR-WEE1 pathway has been well studied in yeasts and animals, how ATR-WEE1 functions in plants remains unclear. Through a genetic screen for suppressors of ... Read more >>

Nucleic Acids Res (Nucleic acids research)
[2021, :]

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Late-onset Hearing Loss From Congenital Cytomegalovirus Infection After Newborn Period in a Highly Immune Population in China.

Chengbin Wang, Xiaolin Liu, Shiwen Wang, Wenqiang Zhang, Haiyan Wang, Wei Ma, Xiangxin Meng, Xingqu Xu, Zhan Li, Qiang Pan, Shuxia Zhang, Ping Wang, Qian Lin, Xiaofang Wang, Minal Amin, Sheila Dollard, Aiqiang Xu, Winnie Chung,

After following 141 children with likely asymptomatic congenital cytomegalovirus infection in a highly immune population in China, four children (2.8%) were found to have late-onset hearing loss. No maternal or childhood factors, except higher saliva cytomegalovirus viral load at birth (P = 0.03), were associated with increased risk of developing ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(1):70-73]

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Highly Selective Separation of Rare Earth Elements by Zn-BTC Metal-Organic Framework/Nanoporous Graphene via In Situ Green Synthesis.

Jinsheng Wu, Zhan Li, Hongxin Tan, Shaobo Du, Tianqi Liu, Yanli Yuan, Xiuhui Liu, Hongdeng Qiu,

Rare earth elements (REEs) are used widely in devices of many fields, but it is still a troublesome task to achieve their selective separation and purification. Metal-organic frameworks (MOFs) as an emerging porous crystalline material have been used for selective separation of REEs using the size-selective crystallization properties. However, so ... Read more >>

Anal Chem (Analytical chemistry)
[2020, :]

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Nitrogen-doped nanoporous graphene induced by a multiple confinement strategy for membrane separation of rare earth.

Hongxin Tan, Xin Zhang, Zhan Li, Qing Liang, Jinsheng Wu, Yanli Yuan, Shiwei Cao, Jia Chen, Juewen Liu, Hongdeng Qiu,

Rare earth separation is still a major challenge in membrane science. Nitrogen-doped nanoporous graphene (NDNG) is a promising material for membrane separation, but it has not yet been tested for rare earth separation, and it is limited by multi-complex synthesis. Herein, we developed a one-step, facile, and scalable approach to ... Read more >>

iScience (iScience)
[2021, 24(1):101920]

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HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer.

Xue-Ting Hu, Wei Xing, Rong-Sen Zhao, Yan Tan, Xiao-Feng Wu, Luo-Quan Ao, Zhan Li, Meng-Wei Yao, Mu Yuan, Wei Guo, Shang-Ze Li, Jian Yu, Xiang Ao, Xiang Xu,

<h4>Background</h4>Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis. Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators. Here, we elucidated a novel role of histone deacetylase 2 (HDAC2) in regulating EMT and CRC metastasis via ncRNA.<h4>Methods</h4>The expression of HDACs in CRC was analyzed ... Read more >>

J Exp Clin Cancer Res (Journal of experimental & clinical cancer research : CR)
[2020, 39(1):270]

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The value of virtual bronchoscopic navigation and radial endobronchial ultrasound-guided transbronchial lung cryobiopsies for pulmonary lymphangitic carcinomatosis.

Lingling Pang, Tingshu Jiang, Xueping Liu, Zhan Li, Shenchun Zou, Pengfei Yu,

<h4>Background</h4>Pulmonary lymphangitic carcinomatosis (PLC) is characterized by malignant infiltration into lung lymphatic channels from a primary site and is often observed in advanced malignant tumors. This study aimed to evaluate the diagnostic yield of transbronchial lung cryobiopsy in PLC guided by radial endobronchial ultrasound and virtual bronchoscopic navigation (VBN).<h4>Methods</h4>This prospective ... Read more >>

J Thorac Dis (Journal of thoracic disease)
[2020, 12(12):7666-7674]

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Experiences and views of people with diabetes during Ramadan fasting: A qualitative meta-synthesis.

Jieying Liao, Tianfang Wang, Zhan Li, Haotian Xie, Shanshan Wang,

<h4>Objectives</h4>To review and appraise the existing qualitative studies on Ramadan fasting in participants with diabetes and to integrate valuable qualitative evidence for optimizing diabetes management.<h4>Methods</h4>Twelve databases (PubMed, Embase, Cochrane Library, Science Direct, CINAHL, PsycINFO, JBI (Joanna Briggs institute), Web of Science, and four Chinese databases) were searched to identify qualitative ... Read more >>

PLoS One (PloS one)
[2020, 15(11):e0242111]

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Ultrabright Quantum Photon Sources on Chip.

Zhaohui Ma, Jia-Yang Chen, Zhan Li, Chao Tang, Yong Meng Sua, Heng Fan, Yu-Ping Huang,

Quantum photon sources of high rate, brightness, and purity are increasingly desirable as quantum information systems are quickly scaled up and applied to many fields. Using a periodically poled lithium niobate microresonator on chip, we demonstrate photon-pair generation at high rates of 8.5 and 36.3 MHz using only 3.4 and 13.4  μW ... Read more >>

Phys Rev Lett (Physical review letters)
[2020, 125(26):263602]

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Construction of Position-Controllable Graphene Bubbles in Liquid Nitrogen with Assistance of Low-Power Laser.

Xin Zhang, Haojie Zhang, Shiwei Cao, Ning Zhang, Bo Jin, Zewen Zong, Zhan Li, Ximeng Chen,

Graphene bubbles (GBs) are of significant interest owing to their distinguished electrical, optical, and magnetic properties. GBs can also serve as high-pressure reaction vessels to numerous chemical reactions. However, previous strategies to produce GBs are relatively elaborate and random. Therefore, their potential applications are severely restricted. Here, a facile and ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2020, 12(50):56260-56268]

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HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer

Xue-ting Hu, Wei Xing, Rong-sen Zhao, Yan Tan, Xiao-feng Wu, Luo-quan Ao, Zhan Li, Meng-wei Yao, Mu Yuan, Wei Guo, Shang-ze Li, Jian Yu, Xiang Ao, xiang xu,

<h4>Background: </h4> Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis . Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators. Here, we elucidated a novel role of histone deacetylase 2 ( HDAC2 ) in regulating EMT and CRC metastasis via ncRNA. <h4>Methods: </h4> ... Read more >>

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Bifunctional and Bioreducible Dendrimer Bearing a Fluoroalkyl Tail for Efficient Protein Delivery Both In Vitro and In Vivo.

Jia Lv, Changping Wang, Hongru Li, Zhan Li, Qianqian Fan, Ying Zhang, Yiwen Li, Hui Wang, Yiyun Cheng,

Rational design of stimuli-responsive polymers for cytosolic protein delivery with robust efficiency is of great importance but remains a challenging task. Here, we reported a bioreducible and amphiphilic dendrimer bearing a fluoroalkyl tail for this purpose. The fluorolipid was conjugated to the focal point of a cysteamine-cored polyamidoamine dendrimer via ... Read more >>

Nano Lett (Nano letters)
[2020, 20(12):8600-8607]

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Anomalous slowdown of pump light in Raman fiber lasers.

Wenchao Wang, Tianhao Xian, Lirun Gao, Wenyan Zhang, Li Zhan,

Usually, the pump light in lasers should perform fast light owing to operating in the absorption band. In this study, we observe and demonstrate anomalous slowdown of the pump light in a Raman fiber laser. Experiments show that the pump light can be slowed down to sub-nanoseconds at a repetition ... Read more >>

Opt Lett (Optics letters)
[2020, 45(22):6226-6229]

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Manganese-mediated reductive functionalization of activated aliphatic acids and primary amines.

Zhan Li, Ke-Feng Wang, Xin Zhao, Huihui Ti, Xu-Ge Liu, Honggen Wang,

Alkyl carboxylic acids as well as primary amines are ubiquitous in all facets of biological science, pharmaceutical science, chemical science and materials science. By chemical conversion to redox-active esters (RAE) and Katritzky's N-alkylpyridinium salts, respectively, alkyl carboxylic acids and primary amines serve as ideal starting materials to forge new connections. ... Read more >>

Nat Commun (Nature communications)
[2020, 11(1):5036]

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Acute noise causes down-regulation of ECM protein expression in guinea pig cochlea

Min Shi, Lei Shi, Daxiong Ding, Yiyong Hu, Guowei Qi, Li Zhan, Yuhua Zhu, Ping Lv, Ning Yu,

<h4>Objective</h4> To study the differences in cochlea protein expression before and after noise exposure using proteomics to reveal the pathological mechanism of noise-induced hearing loss (NIHL). <h4>Methods</h4> A guinea pig NIHL model was established to test the ABR thresholds before and after noise exposure. The proteomics technology was used to ... Read more >>

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Automatic Recognition of Auditory Brainstem Response Characteristic Waveform based on BiLSTM

Cheng Chen, Li Zhan, Xiaoxin Pan, Zhiliang Wang, Xiaoyu Guo, Handai Qin, Fen Xiong, Wei Shi, Min Shi, Fei Ji, Qiuju Wang, Ning Yu, Ruoxiu Xiao,

<h4>Background</h4> Auditory brainstem response (ABR) test is widely used in newborn hearing screening and hearing disease diagnosis. Identifying and marking are challenging and repetitive tasks because of complex rules of ABR characteristic waveform and interference of background noise. <h4>Methods</h4> This study proposes an automatic method to recognize ABR characteristic waveform. ... Read more >>

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Subharmonic Entrainment Breather Solitons in Ultrafast Lasers.

Tianhao Xian, Li Zhan, Wenchao Wang, Wenyan Zhang,

We study theoretically and experimentally the subharmonic entrainment (SHE) breather soliton in mode-locked lasers for the first time, in which the ratio of the breather period to the round-trip time is an integer. We build a non-Hermitian degeneracy map of breather soliton, and illustrate that SHE arises between the two ... Read more >>

Phys Rev Lett (Physical review letters)
[2020, 125(16):163901]

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Correction: Photothermal conversion of gold nanoparticles for uniform pulsed laser warming of vitrified biomaterials.

Yilin Liu, Joseph Kangas, Yiru Wang, Kanav Khosla, Jacqueline Pasek-Allen, Li Zhan, Aaron Saunders, Steven Oldenburg, John Bischof,

Correction for 'Photothermal conversion of gold nanoparticles for uniform pulsed laser warming of vitrified biomaterials' by Yilin Liu et al., Nanoscale, 2020, 12, 12346-12356, DOI: 10.1039/D0NR01614D. ... Read more >>

Nanoscale (Nanoscale)
[2020, 12(39):20543]

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Cryopreservation and Laser Nanowarming of Zebrafish Embryos Followed by Hatching and Spawning.

Kanav Khosla, Joseph Kangas, Yilin Liu, Li Zhan, Jonathan Daly, Mary Hagedorn, John Bischof,

This study shows for the first time the ability to rewarm cryopreserved zebrafish embryos that grow into adult fish capable of breeding normally. The protocol employs a single injection of cryoprotective agents (CPAs) and gold nanorods (GNRs) into the yolk and immersion in a precooling bath to dehydrate the perivitelline ... Read more >>

Adv Biosyst (Advanced biosystems)
[2020, 4(11):e2000138]

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Preparation of Vortex Porous Graphene Chiral Membrane for Enantioselective Separation.

Hongxin Tan, Tianqi Liu, Xin Zhang, Qiang Shan, Jia Chen, Zhan Li, Hirotaka Ihara, Hongdeng Qiu,

Chiral materials are usually the key to the separation of chiral membranes. In this work, we propose a new strategy that chiral porous graphene membrane can be fabricated from nonchiral porous graphene by mechanical stirring to induce vortex structure. Porous graphene with controlled, nanosized pores was synthesized by a newly ... Read more >>

Anal Chem (Analytical chemistry)
[2020, 92(20):13630-13633]

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A new ZIF molecular-sieving membrane for high-efficiency dye removal.

Zhan Li, Pingping Yang, Zhuangzhuang Gao, Mingqiu Song, Qianrong Fang, Ming Xue, Shilun Qiu,

A new and robust ZIF membrane was successfully prepared and evaluated for dye removal capacity. Benefitting from its favourable pore structure and thin selective layer, this ZIF membrane showed excellent removal efficiency for a variety of dyes, with rejection rates of over 99.8% and high water flux up to ∼100 ... Read more >>

Chem Commun (Camb) (Chemical communications (Cambridge, England))
[2019, 55(24):3505-3508]

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Influence of nanopore density on ethylene/acetylene separation by monolayer graphene.

Bo Jin, Xin Zhang, Fei Li, Ning Zhang, Zewen Zong, Shiwei Cao, Zhan Li, Ximeng Chen,

The use of nanoporous graphene for separation has attracted increasing interest over the past few years. Nanopore size, temperature, pressure and functionalization are vital for selectivity, but the influence of nanopore density is not known. Thus, we designed a monolayer nanoporous graphene membrane and revealed the influence of nanopore density ... Read more >>

Phys Chem Chem Phys (Physical chemistry chemical physics : PCCP)
[2019, 21(11):6126-6132]

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Efficient and highly tunable second-harmonic generation in Z-cut periodically poled lithium niobate nanowaveguides.

Jia-Yang Chen, Chao Tang, Zhao-Hui Ma, Zhan Li, Yong Meng Sua, Yu-Ping Huang,

Thin-film lithium-niobate-on-insulator (LNOI) has emerged as a superior integrated-photonics platform for linear, nonlinear, and electro-optics. Here we combine quasi-phase-matching, dispersion engineering, and tight mode confinement to realize nonlinear parametric processes with both high efficiency and wide wavelength tunability. On a millimeter-long, Z-cut LNOI waveguide, we demonstrate efficient (1900±500%W-1cm-2) and highly ... Read more >>

Opt Lett (Optics letters)
[2020, 45(13):3789-3792]

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Antioxidant shape amphiphiles for accelerated wound healing.

Zhan Li, Jianhua Zhang, Yu Fu, Lu Yang, Fang Zhu, Xianhu Liu, Zhipeng Gu, Yiwen Li,

Shape amphiphiles refer to a class of molecular conjugates composed by distinct building blocks with incommensurate shapes and chemical interactions. Whilst extensive efforts have been devoted to the solid state self-assembly and nanolithography applications of shape amphiphiles, only very limited examples of their usage in the biomedical field have been ... Read more >>

J Mater Chem B (Journal of materials chemistry. B)
[2020, 8(31):7018-7023]

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