Full Text Journal Articles by
Author Zeeshan Ahmed

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Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis.

Zeeshan Ahmed,

Precision medicine aims to empower clinicians to predict the most appropriate course of action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID-19. With a progressive interpretation of the clinical, molecular, and genomic factors at play in diseases, more effective and personalized medical treatments are anticipated for many ... Read more >>

Hum Genomics (Human genomics)
[2020, 14(1):35]

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The impact of COVID-19 on an Irish vascular unit's service.

Mary J Connolly, Zeeshan Ahmed, Sayed Aly, Daragh Moneley, Elrasheid Kheirelseid, Peter Naughton, Seamus McHugh,

J. Vasc. Surg. (Journal of vascular surgery)
[2020, :]

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COVID-19 and comorbidities: Deleterious impact on infected patients.

Hasan Ejaz, Abdullah Alsrhani, Aizza Zafar, Humera Javed, Kashaf Junaid, Abualgasim E Abdalla, Khalid O A Abosalif, Zeeshan Ahmed, Sonia Younas,

The pandemic situation with the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from China has endangered human lives. Coronavirus disease 2019 (COVID-19) is presented with asymptomatic, mild, or severe pneumonia-like symptoms. COVID-19 patients with diabetes, chronic obstructive pulmonary disease (COPD), cardiovascular diseases (CVD), hypertension, malignancies, HIV, and other ... Read more >>

J Infect Public Health (Journal of infection and public health)
[2020, :]

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Food as medicine: A possible preventive measure against coronavirus disease (COVID-19).

Fan Yang, Yue Zhang, Akash Tariq, Xiaolan Jiang, Zeeshan Ahmed, Zhang Zhihao, Muhammad Idrees, Azizullah Azizullah, Muhammad Adnan, Rainer W Bussmann,

The recent and ongoing outbreak of coronavirus disease (COVID-19) is a huge global challenge. The outbreak, which first occurred in Wuhan City, Hubei Province, China and then rapidly spread to other provinces and to more than 200 countries abroad, has been declared a global pandemic by the World Health Organization. ... Read more >>

Phytother Res (Phytotherapy research : PTR)
[2020, :]

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100 Years of evolving gene-disease complexities and scientific debutants.

Saman Zeeshan, Ruoyun Xiong, Bruce T Liang, Zeeshan Ahmed,

It's been over 100 years since the word `gene' is around and progressively evolving in several scientific directions. Time-to-time technological advancements have heavily revolutionized the field of genomics, especially when it's about, e.g. triple code development, gene number proposition, genetic mapping, data banks, gene-disease maps, catalogs of human genes and ... Read more >>

Brief. Bioinformatics (Briefings in bioinformatics)
[2020, 21(3):885-905]

Cited: 3 times

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CRISPR-Cas9, A Promising Therapeutic Tool for Cancer Therapy: A Review.

Fatima Akram, Ikram Ul Haq, Zeeshan Ahmed, Hamza Khan, Muhammad Shrafat Ali,

Cancer is one of the most leading causes of mortality all over the world and remains a foremost social and economic burden. Mutations in the genome of individuals are taking place more frequently due to the excessive progress of xenobiotics and industrialization in the present world. With the progress in ... Read more >>

Protein Pept. Lett. (Protein and peptide letters)
[2020, :]

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Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis

Zeeshan Ahmed,

Precision medicine aims to empower clinicians to predict the most appropriate course of action for patients with complex diseases like cancer, diabetes, cardiomyopathy, and COVID-19. With a progressive interpretation of the clinical, molecular, and genomic factors at play in diseases, more effective and personalized medical treatments are anticipated for many ... Read more >>

Hum. Genomics (Human genomics)
[2020, 14(1):]

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Human gene and disease associations for clinical-genomics and precision medicine research.

Zeeshan Ahmed, Saman Zeeshan, Dinesh Mendhe, XinQi Dong,

We are entering the era of personalized medicine in which an individual's genetic makeup will eventually determine how a doctor can tailor his or her therapy. Therefore, it is becoming critical to understand the genetic basis of common diseases, for example, which genes predispose and rare genetic variants contribute to ... Read more >>

(Clinical and translational medicine)
[2020, 10(1):297-318]

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Automatization analysis of the extremely sensitive laser-based dual-mode biomedical sensor.

Usman Masud, Muhammad Iram Baig, Ahmed Zeeshan,

In order to design and manufacture a reliable biomedical sensor, sensitive tests have to be performed. This is of superlative importance as it has to be used for the general public. Keeping this into account, the test mechanism of such an extremely sensitive sensor is being done that involves exhaustive ... Read more >>

Lasers Med Sci (Lasers in medical science)
[2020, 35(7):1531-1542]

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Optical Trocar Causing Aortic Injury: A Potentially Fatal Complication of Minimal Access Surgery.

Rashid Usman, Hafsa Ahmed, Zeeshan Ahmed, Maqsood Ali,

Trocar injury to abdominal aorta is uncommon and even rare with optical trocars. Such injury, resulting from umbilical trocar insertion, is potentially fatal. It often causes on-table death due to torrential life-threatening haemorrhage and unavailability of expert vascular help. We present a rare case of an injury to infra-renal abdominal ... Read more >>

J Coll Physicians Surg Pak (Journal of the College of Physicians and Surgeons--Pakistan : JCPSP)
[2020, 30(1):85-87]

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Artificial intelligence with multi-functional machine learning platform development for better healthcare and precision medicine.

Zeeshan Ahmed, Khalid Mohamed, Saman Zeeshan, XinQi Dong,

Precision medicine is one of the recent and powerful developments in medical care, which has the potential to improve the traditional symptom-driven practice of medicine, allowing earlier interventions using advanced diagnostics and tailoring better and economically personalized treatments. Identifying the best pathway to personalized and population medicine involves the ability ... Read more >>

Database (Oxford) (Database : the journal of biological databases and curation)
[2020, 2020:]

Cited: 2 times

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Debutant iOS app and gene-disease complexities in clinical genomics and precision medicine.

Zeeshan Ahmed, Saman Zeeshan, Ruoyun Xiong, Bruce T Liang,

BACKGROUND:The last decade has seen a dramatic increase in the availability of scientific data, where human-related biological databases have grown not only in count but also in volume, posing unprecedented challenges in data storage, processing, analysis, exchange, and curation. Next generation sequencing (NGS) advancements have facilitated and accelerated the process ... Read more >>

(Clinical and translational medicine)
[2019, 8(1):26]

Cited: 1 time

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Response to comment on Asad Maqbool Ahmad et al. (JPMA 2018; 68: 1613) -- Granulocyte-colony stimulating factor in neonatal sepsis with leukopenia: A prospective cohort study.

Asad Maqbool Ahmad, Zeeshan Ahmed, Talal Waqar, Arshad Khushdil,

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2019, 69(9):1405]

Cited: 0 times

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A Photonic pH Sensor Based on Photothermal Spectroscopy

Matthew Hartings, Nathan J. Castro, Zeeshan Ahmed,

Although the determination of pH is a standard laboratory measurement, new techniques capable of measuring pH are being developed to facilitate modern technological advances. Bio-industrial processing, tissue engineering, and intracellular environments impose unique measurement requirements on probes of pH. We describe a fiber optic-based platform, which measures the heat released ... Read more >>

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Current laboratory techniques commonly used for the detection of molecular biomarkers and potential technologies on the horizon.

Muhammad Shariq Shaikh, Zeeshan Ansar Ahmed,

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2019, 69(7):1063]

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Spectrum of dystrophin gene mutations observed in patients suspected of Duchenne muscular dystrophy in Pakistan

Zeeshan Ahmed,

Clin Med (Lond) (Clinical medicine (London, England))
[2019, 19(Suppl 3):32-32]

Cited: 0 times

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Yunis-Varon Syndrome.

Abdul Wahab Siddique, Zeeshan Ahmed, Ammar Haider, Hina Khalid, Tooba Karim,

Yunis-Varon syndrome is a rare autosomal recessive disorder with characteristic facial features and limb anomalies. We report a neonate born to consanguineously married normal parents with typical clinical and radiologic features of Yunis-Varon syndrome along with complete cleft lip and palate: an infrequent association. The family had two previous babies ... Read more >>

J Ayub Med Coll Abbottabad (Journal of Ayub Medical College, Abbottabad : JAMC)
[2019, 31(2):290-292]

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Tumour lysis syndrome in a patient with undifferentiated endometrial stromal sarcoma.

Zeeshan Ahmed, Ahmed Barefah, Parveen Wasi, Graham Jones, Jennifer Ramsay,

•Tumour lysis syndrome is an oncologic emergency.•Tumour lysis syndrome is most commonly encountered in hematologic malignancies.•Herein we report a case of tumour lysis syndrome in an endometrial stromal sarcoma. ... Read more >>

(Gynecologic oncology reports)
[2019, 28:41-43]

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Granulocyte-colony stimulating factor in neonatal sepsis with leukopenia: A prospective cohort study.

Asad Maqbool Ahmad, Zeeshan Ahmed, Arshad Khushdil, Talal Waqar,

OBJECTIVE:To observe the duration for normalization of the Total Leucocyte Count (TLC) with adjuvant Granulocyte-Colony Stimulating Factor (G-CSF) treatment in leukopenic neonatal sepsis, and to compare the neutrophilic response to G-CSF in neutropenic vs non-neutropenic subgroups. METHODS:This prospective cohort study was carried out at the Neonatal Intensive Care Unit at ... Read more >>

J Pak Med Assoc (JPMA. The Journal of the Pakistan Medical Association)
[2018, 68(11):1613-1617]

Cited: 0 times

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A photonic pH sensor based on photothermal spectroscopy.

Matthew R Hartings, Nathan J Castro, Kathryn Gill, Zeeshan Ahmed,

Although the determination of pH is a standard laboratory measurement, new techniques capable of measuring pH are being developed to facilitate modern technological advances. Bio-industrial processing, tissue engineering, and intracellular environments impose unique measurement requirements on probes of pH. We describe a fiber optic-based platform, which measures the heat released ... Read more >>

Sens Actuators B Chem (Sensors and actuators. B, Chemical)
[2019, 301:]

Cited: 0 times

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MAV-clic: management, analysis, and visualization of clinical data.

Zeeshan Ahmed, Minjung Kim, Bruce T Liang,

Objectives:Develop a multifunctional analytics platform for efficient management and analysis of healthcare data. Materials and Methods:Management, Analysis, and Visualization of Clinical Data (MAV-clic) is a Health Insurance Portability and Accountability Act of 1996 (HIPAA)-compliant framework based on the Butterfly Model. MAV-clic extracts, cleanses, and encrypts data then restructures and aggregates ... Read more >>

JAMIA Open (JAMIA open)
[2019, 2(1):23-28]

Cited: 1 time

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Role of Corticosteroids in Reducing Respiratory Morbidity in Neonates Delivered by Elective Cesarean Section before 39 Weeks.

Arshad Khushdil, Shehla Baqai, Madiha Ahmed, Zeeshan Ahmed,

OBJECTIVE:To determine the effect of dexamethasone administration to women between 37 to 39 weeks of gestation on neonatal outcome in terms of respiratory morbidity and the need for NICU admission. STUDY DESIGN:An experimental study. PLACE AND DURATION OF STUDY:Department of Obstetrics and Department of Neonatology, Military Hospital, Rawalpindi, Pakistan, from ... Read more >>

J Coll Physicians Surg Pak (Journal of the College of Physicians and Surgeons--Pakistan : JCPSP)
[2018, 28(12):906-909]

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Fabrication and Testing of Photonic Thermometers.

Nikolai N Klimov, Zeeshan Ahmed,

In recent years, a push for developing novel silicon photonic devices for telecommunications has generated a vast knowledge base that is now being leveraged for developing sophisticated photonic sensors. Silicon photonic sensors seek to exploit the strong confinement of light in nano-waveguides to transduce changes in physical state to changes ... Read more >>

J Vis Exp (Journal of visualized experiments : JoVE)
[2018, (140):]

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A Novel Clinico-Biochemical Score for Screening of Inherited Metabolic Diseases in Children.

Oshaque Ali, Ayesha Hafeez, Aamir Ijaz, Munir Akmal Lodhi, Muhammad Asif Nawaz, Zeeshan Ahmed,

OBJECTIVE:To evaluate a novel clinico-biochemical score for screening of inherited metabolic diseases (IMDs) in children in our setup. STUDY DESIGN:Descriptive analytical study. PLACE AND DURATION OF STUDY:Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, from August 2016 to August 2017. METHODOLOGY:Clinical data, preliminary biochemical investigations, plasma ... Read more >>

J Coll Physicians Surg Pak (Journal of the College of Physicians and Surgeons--Pakistan : JCPSP)
[2018, 28(11):853-857]

Cited: 1 time

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A study of outcomes in conservatively managed patients with large abdominal aortic aneurysms deemed unfit for surgical repair.

Ahmed Elmallah, Mohamed Elnagar, Niamh Bambury, Zeeshan Ahmed, Joseph Dowdall, Denis Mehigan, Stephen Sheehan, Mary Barry,

BACKGROUND:The current advancement and increasing use of diagnostic imaging has led to increased detection of abdominal aortic aneurysms (AAA). Many of these patients are unfit for elective AAA surgery. AIM:To investigate the outcome of conservative management of unfit patients with large AAA (>5.5 cm) who are turned down for elective ... Read more >>

Vascular (Vascular)
[2019, 27(2):161-167]

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