Full Text Journal Articles by
Author Zahid Ali

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Prevalence of QTc interval prolongation and its associated risk factors among psychiatric patients: a prospective observational study.

Zahid Ali, Mohammad Ismail, Zahid Nazar, Fahadullah Khan, Qasim Khan, Sidra Noor,

BACKGROUND:QT interval prolongation is a growing concern worldwide, posing psychiatric patients to life-threatening fatal arrhythmias i.e., torsade de pointes. This study aimed to identify the prevalence of QT interval prolongation, its associated risk factors and prescribing patterns of QT prolonging drugs among psychiatric patients. METHOD:A prospective observational study was conducted ... Read more >>

BMC Psychiatry (BMC psychiatry)
[2020, 20(1):277]

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Captivity stress influences the DNA damage of Pavo cristatus under environmental conditions of Faisalabad, Pakistan.

Shabana Naz, Shifa Muazzam, Anila Sagheer, Arnab Tanveer, Nishat Ali Khan, Zahid Ali, Naila Chand, Rifat Ullah Khan,

The surroundings of wild and captive birds are divergent in existence. Wild birds inhabiting their natural environment have unlimited resources availability. They face variety of captivity stresses when moved from wild habitat to caged enclosures. The effect of similar captivity stresses on the DNA of birds living in cages for ... Read more >>

Environ Sci Pollut Res Int (Environmental science and pollution research international)
[2020, 27(5):5636-5639]

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Potential drug-drug interactions among pneumonia patients: do these matter in clinical perspectives?

Sidra Noor, Mohammad Ismail, Zahid Ali,

BACKGROUND:Pneumonia patients are usually hospitalized due to severe nature of the disease or for the management of comorbid illnesses or associated symptoms. Such patients are prescribed with multiple medications which increase the likelihood of potential drug-drug interactions (pDDIs). Therefore, in this study the prevalence, levels (severity and documentation), predictors (risk ... Read more >>

BMC Pharmacol Toxicol (BMC pharmacology & toxicology)
[2019, 20(1):45]

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Efficient and reproducible somatic embryogenesis and micropropagation in tomato via novel structures - Rhizoid Tubers.

Wajeeha Saeed, Saadia Naseem, Daniyal Gohar, Zahid Ali,

A dual in vitro regeneration system consisting of indirect organogenesis and somatic embryogenesis (SE), applicable to several varieties of tomato-Solanum lycopersicum (cv. Riogrande, cv. Roma, hybrid 17905 and model cv. M82) has been established. This system is both improved and highly reproducible compared to current methods. Callus initiation, plant regeneration ... Read more >>

PLoS ONE (PloS one)
[2019, 14(5):e0215929]

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The dawn of phage therapy.

Sana Rehman, Zahid Ali, Momna Khan, Nazish Bostan, Saadia Naseem,

Bacteriophages or phages, being the most abundant entities on earth, represent a potential solution to a diverse range of problems. Phages are successful antibacterial agents whose use in therapeutics was hindered by the discovery of antibiotics. Eventually, because of the development and spread of antibiotic resistance among most bacterial species, ... Read more >>

Rev. Med. Virol. (Reviews in medical virology)
[2019, 29(4):e2041]

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Anopheles sundaicus Mosquitoes as Vector for Plasmodium knowlesi, Andaman and Nicobar Islands, India.

Pachalil Thiruvoth Vidhya, Ittoop Pulikkottil Sunish, Anwesh Maile, Ali Khan Zahid,

Using PCR and sequencing, we found Plasmodium knowlesi in the malaria vector Anopheles sundaicus mosquito collected from Katchal Island in the Andaman and Nicobar Islands, India. We cannot rule out natural transmission of this parasite to humans through this mosquito species. An in-depth investigation is needed to prevent disease outbreaks. ... Read more >>

Emerging Infect. Dis. (Emerging infectious diseases)
[2019, 25(4):817-820]

Cited: 1 time

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Knowledge and Practice of Pharmacists toward Antimicrobial Stewardship in Pakistan.

Inayat Ur Rehman, Malik Muhammad Asad, Allah Bukhsh, Zahid Ali, Humera Ata, Juman Abdulelah Dujaili, Ali Qais Blebil, Tahir Mehmood Khan,

Background: The irrational use, "over the counter supply", and unregulated supply chains of antimicrobials are contributing toward antimicrobial resistance. Antimicrobial stewardship programs regulate antimicrobials usage to prevent resistance and reduce health care burden. Objective: To assess the knowledge and practice of pharmacists' working in various healthcare settings toward antimicrobial stewardship ... Read more >>

Pharmacy (Basel) (Pharmacy (Basel, Switzerland))
[2018, 6(4):]

Cited: 2 times

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Potential drug-drug interactions in outpatient department of a tertiary care hospital in Pakistan: a cross-sectional study.

Mohammad Ismail, Sidra Noor, Umme Harram, Inamul Haq, Iqbal Haider, Faiza Khadim, Qasim Khan, Zahid Ali, Tahir Muhammad, Muhammad Asif,

BACKGROUND:Potential drug-drug interactions (pDDIs) are one of the preventable drug related problems having the risk of serious adverse events or therapeutic failure. In developing countries like Pakistan, this issue remains poorly addressed. The objective of this study was to explore prevalence of pDDIs in the Outpatient Department (OPD) of a ... Read more >>

BMC Health Serv Res (BMC health services research)
[2018, 18(1):762]

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Computational modeling and functional characterization of a GgChi: A class III chitinase from corms of Gladiolus grandiflorus.

Maria Rafiq, Ashiq Hussain, Kausar Hussain Shah, Qamar Saeed, Muhammad Umair Sial, Zahid Ali, Friedrich Buck, Richard E Goodman, Binish Khaliq, Uzma Ishaq, Mirza Ahsen Baig, Aisha Munawar, Seema Mahmood, Ahmed Akrem,

The present study describes the predicted model and functional characterization of an endochitinase (30 kDa) from corms of Gladiolus grandiflorus. ESI-QTOF-MS generated peptide showed 96% sequence homology with family 18, Class III acidic endochitinase of Gladiolus gandavensis. Purified G. grandiflorus chitinase (GgChi) hydrolyzed 4-methylumbelliferyl β-d-N,N',N''-triacetylchitotriose substrate showing specific endochitinase activity. Since ... Read more >>

Kaohsiung J. Med. Sci. (The Kaohsiung journal of medical sciences)
[2018, 34(12):673-683]

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Efficient and reproducible somatic embryogenesis and micro propagation in tomato via novel structures -Rhizoid Tubers

Wajeeha Saeed, Saadia Naseem, Daniyal Gohar, Zahid Ali,

Abstract An improved and highly reproducible system for invitro regeneration via somatic embryogenesis (S.E), applicable to several varieties of tomato (cv. Riogrande , cv. Roma grande , hybrid 17905 and model cv. M82) has been developed. First, we developed a conventional indirect organogenesis for all four varieties used in this ... Read more >>

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Moxifloxacin-induced QT interval prolongation and torsades de pointes: a narrative review.

Fahadullah Khan, Mohammad Ismail, Qasim Khan, Zahid Ali,

INTRODUCTION:Moxifloxacin is widely used for the treatment of a number of infectious diseases because of its favorable pharmacological profile and high clinical success rate. However, it is often criticized for its higher risk of QTc interval prolongation (QTIP) and torsades de pointes (TdP). AREAS COVERED:A review of published literature on ... Read more >>

Expert Opin Drug Saf (Expert opinion on drug safety)
[2018, 17(10):1029-1039]

Cited: 2 times

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Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy.

Aoibhinn McDonnell, Susie Collins, Zahid Ali, Laura Iavarone, Raulin Surujbally, Simon Kirby, Richard P Butt,

The effect of PF-05089771, a selective, peripherally restricted Nav1.7 sodium channel blocker on pain due to diabetic peripheral neuropathy was investigated in a randomised, placebo and active-controlled parallel group clinical trial (NCT02215252). A 1-week placebo-run in the period was followed by a 4-week treatment period and a 1-week placebo run-out/taper-down ... Read more >>

Pain (Pain)
[2018, 159(8):1465-1476]

Cited: 10 times

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Structure-activity relationships of strigolactones via a novel, quantitative in planta bioassay.

Elena Sanchez, Emma Artuso, Chiara Lombardi, Ivan Visentin, Beatrice Lace, Wajeeha Saeed, Marco L Lolli, Piermichele Kobauri, Zahid Ali, Francesca Spyrakis, Pilar Cubas, Francesca Cardinale, Cristina Prandi,

Strigolactones (SLs) are plant hormones with various functions in development, responses to stress, and interactions with (micro)organisms in the rhizosphere, including with seeds of parasitic plants. Their perception for hormonal functions requires an α,β-hydrolase belonging to the D14 clade in higher plants; perception of host-produced SLs by parasitic seeds relies ... Read more >>

J. Exp. Bot. (Journal of experimental botany)
[2018, 69(9):2333-2343]

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Prevalence of the risk factors for QT prolongation and associated drug-drug interactions in a cohort of medical inpatients.

Qasim Khan, Mohammad Ismail, Iqbal Haider, Zahid Ali,

BACKGROUND/PURPOSE:Medical inpatients are at increased risk of QT interval prolongation due to multiple risk actors and QT prolonging drugs. This study aimed to identify the prevalence of risk factors for QT prolongation; QT prolonging medications; associated drug-drug interactions (QT-DDIs); their predictors; and TdP (torsades de pointes) risks of drugs. METHODS:This ... Read more >>

J. Formos. Med. Assoc. (Journal of the Formosan Medical Association = Taiwan yi zhi)
[2019, 118(1 Pt 1):109-115]

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Strigolactones Biosynthesis and Their Role in Abiotic Stress Resilience in Plants: A Critical Review.

Wajeeha Saeed, Saadia Naseem, Zahid Ali,

Strigolactones (SLs), being a new class of plant hormones, play regulatory roles against abiotic stresses in plants. There are multiple hormonal response pathways, which are adapted by the plants to overcome these stressful environmental constraints to reduce the negative impact on overall crop plant productivity. Genetic modulation of the SLs ... Read more >>

Front Plant Sci (Frontiers in plant science)
[2017, 8:1487]

Cited: 9 times

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Nickel adsorption onto polyurethane ethylene and vinyl acetate sorbents.

Munawar Iqbal, Zahid Ali, M Afzal Qamar, Abid Ali, Fida Hussain, Mazhar Abbas, Jan Nisar,

The present study was conducted to appraise the efficiencies of polyurethane ethylene sorbent (PES) and vinyl acetate sorbent (VAS) for nickel (Ni) adsorption. Process variables, i.e. Ni(II) ions initial concentration, pH, contact time and adsorbent dosage were optimized by response surface methodology (RSM) approach. The Ni(II) adsorption was fitted to ... Read more >>

Water Sci. Technol. (Water science and technology : a journal of the International Association on Water Pollution Research)
[2017, 76(1-2):219-235]

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Tunable guided-mode resonance filter with a gradient grating period fabricated by casting a stretched PDMS grating wedge.

Chaolong Fang, Bo Dai, Zheng Li, Ali Zahid, Qi Wang, Bin Sheng, Dawei Zhang,

A compact, tunable guided-mode resonant filter (GMRF) is experimentally demonstrated whose spectral reflectance wavelength varies as a function of the illumination position on the device. The GMRF consists of a grating of gradient-varying period ranging from 402.5 to 466.6 nm, which is obtained by casting a stretched polydimethylsiloxane (PDMS) grating ... Read more >>

Opt Lett (Optics letters)
[2016, 41(22):5302-5305]

Cited: 3 times

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Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile.

Aoibhinn McDonnell, Betsy Schulman, Zahid Ali, Sulayman D Dib-Hajj, Fiona Brock, Sonia Cobain, Tina Mainka, Jan Vollert, Sanela Tarabar, Stephen G Waxman,

Inherited erythromelalgia, the first human pain syndrome linked to voltage-gated sodium channels, is widely regarded as a genetic model of human pain. Because inherited erythromelalgia was linked to gain-of-function changes of sodium channel Na(v)1.7 only a decade ago, the literature has mainly consisted of reports of genetic and/or clinical characterization ... Read more >>

Brain (Brain : a journal of neurology)
[2016, 139(Pt 4):1052-1065]

Cited: 19 times

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Potential drug-drug interactions in medical intensive care unit of a tertiary care hospital in Pakistan.

Mohammad Ismail, Farmanullah Khan, Sidra Noor, Iqbal Haider, Inam-Ul Haq, Zahid Ali, Zahir Shah, Mohsin Hassam,

Background Patients admitted to intensive care unit (ICU) present with severe and life-threatening illnesses. Most of them suffer from various comorbidities. They usually receive complex pharmacotherapy with large number of medicines which increase the risk of drug-drug interactions (DDIs). Objective The present report aimed to investigate prevalence and levels of ... Read more >>

Int J Clin Pharm (International journal of clinical pharmacy)
[2016, 38(5):1052-1056]

Cited: 6 times

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Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

Lishuang Cao, Aoibhinn McDonnell, Anja Nitzsche, Aristos Alexandrou, Pierre-Philippe Saintot, Alexandre J C Loucif, Adam R Brown, Gareth Young, Malgorzata Mis, Andrew Randall, Stephen G Waxman, Philip Stanley, Simon Kirby, Sanela Tarabar, Alex Gutteridge, Richard Butt, Ruth M McKernan, Paul Whiting, Zahid Ali, James Bilsland, Edward B Stevens,

In common with other chronic pain conditions, there is an unmet clinical need in the treatment of inherited erythromelalgia (IEM). TheSCN9Agene encoding the sodium channel Nav1.7 expressed in the peripheral nervous system plays a critical role in IEM. A gain-of-function mutation in this sodium channel leads to aberrant sensory neuronal ... Read more >>

Sci Transl Med (Science translational medicine)
[2016, 8(335):335ra56]

Cited: 41 times

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Systematic Review of Computer Based Assessments in Medical Education.

Saad Al-Amri, Zahid Ali,

Medical schools, postgraduate training institutes, licensing and certification bodies have developed and implemented many new methods for accurate, reliable, and timely assessments of the competence of medical professionals and practicing physicians. The underlying objective of all these assessments is to not only evaluate the students' learning and educational goals but ... Read more >>

Saudi J Med Med Sci (Saudi journal of medicine & medical sciences)
[2016, 4(2):79-88]

Cited: 0 times

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RARE CASE OF IDIOPATHIC GINGIVAL FIBROMATOSIS AFFECTING PRIMARY DENTITION.

Sanaa Ahmed, Zahid Ali,

Gingival fibromatosis (GF) is a rare condition with an estimated incidence of 1750,000 in autosomal dominant cases and is supposedly genetic in origin. Gingival fibromatosis (GF) may occur as an isolated finding (Idiopathic gingival fibromatosis or IGF) or in combination with additional clinical problems that is, giving rise to syndromic ... Read more >>

J Ayub Med Coll Abbottabad (Journal of Ayub Medical College, Abbottabad : JAMC)
[2015, 27(4):933-935]

Cited: 0 times

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Mesoporous TiO₂ spheres interconnected by multiwalled carbon nanotubes as an anode for high-performance lithium ion batteries.

Nguyen Thi Hong Trang, Zahid Ali, Dae Joon Kang,

We report on the excellent electrochemical response of lithium ion batteries that use a composite material comprised of mesoporous titanium dioxide (MTO) spheres and multiwalled carbon nanotubes (MWCNTs) for the anode. The composite structure was synthesized via a combined sol-gel and solvothermal method, and the batteries exhibited unprecedented discharge capacity, ... Read more >>

ACS Appl Mater Interfaces (ACS applied materials & interfaces)
[2015, 7(6):3676-3683]

Cited: 3 times

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Naproxen effects on brain response to painful pressure stimulation in patients with knee osteoarthritis: a double-blind, randomized, placebo-controlled, single-dose study.

Mónica Giménez, Jesús Pujol, Zahid Ali, Marina López-Solà, Oren Contreras-Rodríguez, Joan Deus, Héctor Ortiz, Carles Soriano-Mas, Jone Llorente-Onaindia, Jordi Monfort,

The aim of our study was to investigate the effects of naproxen, an antiinflammatory analgesic drug, on brain response to painful stimulation on the affected knee in chronic osteoarthritis (OA) using functional magnetic resonance imaging (fMRI) in a double-blind, placebo-controlled study.A sample of 25 patients with knee OA received naproxen ... Read more >>

J. Rheumatol. (The Journal of rheumatology)
[2014, 41(11):2240-2248]

Cited: 10 times

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Utility of 3-dimensional image reconstruction in the diagnosis of small-bowel masses in capsule endoscopy (with video).

Emanuele Rondonotti, Anastasios Koulaouzidis, Alexandros Karargyris, Andry Giannakou, Lucia Fini, Marco Soncini, Marco Pennazio, Sarah Douglas, Aman Shams, Neil Lachlan, Ali Zahid, Giovanna Mandelli, Carlo Girelli,

In small-bowel capsule endoscopy (SBCE), differentiating masses (ie, lesions of higher probability for neoplasia) requiring more aggressive intervention from bulges (essentially, false-positive findings) is a challenging task; recently, software that enables 3-dimensional (3D) reconstruction has become available.To evaluate whether "coupling" 3D reconstructed video clips with the standard 2-dimensional (s2D) counterparts ... Read more >>

Gastrointest. Endosc. (Gastrointestinal endoscopy)
[2014, 80(4):642-651]

Cited: 10 times

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