Full Text Journal Articles by
Author Zahed Mahmood


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Hantavirus diseases pathophysiology, their diagnostic strategies and therapeutic approaches: A review.

Naveed Munir, Muhammad Jahangeer, Shoukat Hussain, Zahed Mahmood, Mehvish Ashiq, Fatima Ehsan, Muhammad Akram, Syed Muhammad Ali Shah, Muhammad Riaz, Aneezah Sana,

Hantaviruses are enveloped negative (-) single-stranded RNA viruses belongs to Hantaviridae family, hosted by small rodents and entering into the human body through inhalation, causing haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) also known as hantavirus cardiopulmonary syndrome (HCPS). Hantaviruses infect approximately more than 200 000 people ... Read more >>

Clin Exp Pharmacol Physiol (Clinical and experimental pharmacology & physiology)
[2020, :]

Cited: 0 times

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Therapeutic Response of Epimedium gandiflorum's Different Doses to Restore the Antioxidant Potential and Reproductive Hormones in Male Albino Rats.

Naveed Munir, Zahed Mahmood, Muhammad Yameen, Ghulam Mustafa,

Current study was planned to explore the therapeutic response of different doses of hydroethanolic extract of Epimedium grandiflorum leaves in male albino rats. Phytochemical analysis, HPLC and FTIR spectroscopy results revealed the presence of wide range of phenolic compounds and functional groups, respectively. Further, extract not induced significant hemolysis (7.56 ... Read more >>

Dose Response (Dose-response : a publication of International Hormesis Society)
[2020, 18(3):1559325820959563]

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Naegleria fowleri: Sources of infection, pathophysiology, diagnosis, and management; a review.

Muhammad Jahangeer, Zahed Mahmood, Naveed Munir, Umm-E-Amara Waraich, Imtiaz Mahmood Tahir, Muhammad Akram, Syed Muhammad Ali Shah, Syed Muhammad Ali Shah, Ayesha Zulfqar, Rida Zainab,

Naegleria fowleri, a thermophilic flagellate amoeba known as a "brain-eating" amoeba, is the aetiological agent of a perilous and devastating waterborne disease known as primary amoebic meningoencephalitis (PAM), both in humans as well as in animals. PAM is a rare but fatal disease affecting young adults all around the world, ... Read more >>

Clin. Exp. Pharmacol. Physiol. (Clinical and experimental pharmacology & physiology)
[2020, 47(2):199-212]

Cited: 3 times

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Hexose monophosphate shunt, the role of its metabolites and associated disorders: A review.

Muhammad Akram, Syed Muhammad Ali Shah, Naveed Munir, Muhammad Daniyal, Imtiaz Mahmood Tahir, Zahed Mahmood, Muhammad Irshad, Muhammad Akhlaq, Sabira Sultana, Rida Zainab,

The hexose monophosphate (HMP) shunt acts as an essential component of cellular metabolism in maintaining carbon homeostasis. The HMP shunt comprises two phases viz. oxidative and nonoxidative, which provide different intermediates for the synthesis of biomolecules like nucleotides, DNA, RNA, amino acids, and so forth; reducing molecules for anabolism and detoxifying the reactive oxygen species ... Read more >>

J Cell Physiol (Journal of cellular physiology)
[2019, :]

Cited: 0 times

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Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review.

Muhammad Akram, Imtiaz Mahmood Tahir, Syed Muhammad Ali Shah, Zahed Mahmood, Awais Altaf, Khalil Ahmad, Naveed Munir, Muhammad Daniyal, Suhaila Nasir, Huma Mehboob,

Viral infections are being managed therapeutically through available antiviral regimens with unsatisfactory clinical outcomes. The refractory viral infections resistant to available antiviral drugs are alarming threats and a serious health concern. For viral hepatitis, the interferon and vaccine therapies solely are not ultimate solutions due to recurrence of hepatitis C ... Read more >>

Phytother Res (Phytotherapy research : PTR)
[2018, 32(5):811-822]

Cited: 12 times

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Drug resistant strains of Mycobacterium tuberculosis identified through PCR-RFLP from patients of Central Punjab, Pakistan.

Muhammad Riaz, Zahed Mahmood, Muhammad Tariq Javed, Irum Javed, Muhammad Shahid, Mazhar Abbas, Syed Ehtisham-Ul-Haque,

The study was carried out to determine, by PCR-RFLP, the magnitude of drug resistance in Mycobacterium tuberculosis The study was carried out on 221 random sputum samples collected from patients and 120 suspected cases of drug resistance. Genetic variation in drug-resistant strains was evaluated through PCR-RFLP for isoniazid, ethambutol, streptomycin, ... Read more >>

Int J Immunopathol Pharmacol (International journal of immunopathology and pharmacology)
[2016, 29(3):443-449]

Cited: 2 times

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Identification of ofloxacin-resistant Mycobacterium tuberculosis by PCR-RFLP and Sequencing.

Irum Javed, Zahed Mahmood, Muhammad Shahid, Tanweer Khaliq,

This study was planned to verify the resistance frequency of Ofloxacin (OFX) against Mycobacterium tuberculosis by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) technique and sequencing. Total 366 clinical samples of suspected TB patients were collected from various localities of central Punjab. All of them were found positive by ... Read more >>

Pak J Pharm Sci (Pakistan journal of pharmaceutical sciences)
[2016, 29(1 Suppl):281-286]

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Impact of reactive oxygen species on antioxidant capacity of male reproductive system.

Muhammad Riaz, Zahed Mahmood, Muhammad Shahid, M Usman Qamar Saeed, Imtiaz Mahmood Tahir, Sm Ali Shah, Naveed Munir, Ahmed El-Ghorab,

The present research work was aimed to study the mutual interaction of reactive oxygen species (ROS) and basal cells antioxidant capacity in the male reproductive system and to further establish the association between selected heavy metals and stress markers. Total oxidant status (TOS) and total antioxidant status (TAS) of serum ... Read more >>

Int J Immunopathol Pharmacol (International journal of immunopathology and pharmacology)
[2016, 29(3):421-425]

Cited: 3 times

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Variation in minerals, phenolics and antioxidant activity of peel and pulp of different varieties of peach (Prunus persica L.) fruit from Pakistan.

Maleeha Manzoor, Farooq Anwar, Zahed Mahmood, Umer Rashid, Muhammad Ashraf,

Peach (Prunus persica L.), being a potential source of bioactive compounds, has been demonstrated to have medicinal benefits. In this study variation of minerals and antioxidant characteristics (total phenolic contents, total flavonoid contents, reducing power, inhibition of peroxidation using linoleic acid system and DPPH free radical scavenging activity) between peel ... Read more >>

Molecules (Molecules (Basel, Switzerland))
[2012, 17(6):6491-6506]

Cited: 8 times

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