Full Text Journal Articles by
Author Yutian Chong

Advertisement

Find full text journal articles






Association between the nasopharyngeal microbiome and metabolome in patients with COVID-19.

Jing Liu, Sheng Liu, Zhao Zhang, Xuejun Lee, Wenxuan Wu, Zhanlian Huang, Ziying Lei, Wenxiong Xu, Dabiao Chen, Xing Wu, Yang Guo, Liang Peng, Bingliang Lin, Yutian Chong, Xiangyu Mou, Mang Shi, Ping Lan, Tao Chen, Wenjing Zhao, Zhiliang Gao,

SARS-CoV-2, the causative agent for COVID-19, infect human mainly via respiratory tract, which is heavily inhabited by local microbiota. However, the interaction between SARS-CoV-2 and nasopharyngeal microbiota, and the association with metabolome has not been well characterized. Here, metabolomic analysis of blood, urine, and nasopharyngeal swabs from a group of ... Read more >>

Synth Syst Biotechnol (Synthetic and systems biotechnology)
[2021, 6(3):135-143]

Cited: 0 times

View full text PDF listing >>



Unsupervised Hierarchical Clustering Identifies Immune Gene Subtypes in Gastric Cancer.

Jing Cao, Jiao Gong, Xinhua Li, Zhaoxia Hu, Yingjun Xu, Hong Shi, Danyang Li, Guangjian Liu, Yusheng Jie, Bo Hu, Yutian Chong,

<b>Objectives:</b> The pathogenesis of heterogeneity in gastric cancer (GC) is not clear and presents as a significant obstacle in providing effective drug treatment. We aimed to identify subtypes of GC and explore the underlying pathogenesis. <b>Methods:</b> We collected two microarray datasets from GEO (GSE84433 and GSE84426), performed an unsupervised cluster ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2021, 12:692454]

Cited: 0 times

View full text PDF listing >>



Advertisement

Atrial fibrillation increased in-hospital and 4-year all-cause mortality in Critically ill patients with liver cirrhosis

Yanting Luo, Bingyuan Wu, Yuankai Wu, Long Peng, Zexiong Li, Jieming Zhu, Zhongzhen Su, Jinlai Liu, Suhua Li, Yutian Chong,

<h4>Objective: </h4> The purpose of this study was to use a large database that contains information on patient intensive care unit (ICU) admissions to study critically ill patients with cirrhosis and the relation with atrial fibrillation and short-term and 4-year mortality. MethodsThe Monitoring in Intensive Care Database III database was ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



A Simple Nomogram Developed for Predicting HCC Metastasis Based on Micrornas 

Yong Zhu, Yusheng Jie, Yuankai Wu, Wenting Tang, Jing Cao, Zhongzhen Su, ZhenJian Zhuo, Jiao Gong, Yutian Chong,

<h4>Background: </h4> Owing to lack of predictive models for HCC metastasis based on the expression of miRNAs, we aimed to develop a simple model for identification of HCC patients at high risk of metastasis. <h4>Methods: </h4> HCC datasets with metastasis information were acquired from the Gene Expression Omnibus (GEO), and ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Deep learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) with CT images.

Ying Song, Shuangjia Zheng, Liang Li, Xiang Zhang, Xiaodong Zhang, Ziwang Huang, Jianwen Chen, Ruixuan Wang, Huiying Zhao, Yunfei Zha, Jun Shen, Yutian Chong, Yuedong Yang,

A novel coronavirus (COVID-19) has emerged recently as an acute respiratory syndrome. The outbreak was originally reported in Wuhan, China, but has subsequently been spread world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially important for fast diagnoses. Thus, it is urgent ... Read more >>

IEEE/ACM Trans Comput Biol Bioinform (IEEE/ACM transactions on computational biology and bioinformatics)
[2021, PP:]

Cited: 27 times

View full text PDF listing >>



Accurately Discriminating COVID-19 from Viral and Bacterial Pneumonia According to CT Images Via Deep Learning.

Fudan Zheng, Liang Li, Xiang Zhang, Ying Song, Ziwang Huang, Yutian Chong, Zhiguang Chen, Huiling Zhu, Jiahao Wu, Weifeng Chen, Yutong Lu, Yuedong Yang, Yunfei Zha, Huiying Zhao, Jun Shen,

Computed tomography (CT) is one of the most efficient diagnostic methods for rapid diagnosis of the widespread COVID-19. However, reading CT films brings a lot of concentration and time for doctors. Therefore, it is necessary to develop an automatic CT image diagnosis system to assist doctors in diagnosis. Previous studies ... Read more >>

Interdiscip Sci (Interdisciplinary sciences, computational life sciences)
[2021, 13(2):273-285]

Cited: 1 time

View full text PDF listing >>



HCC subtypes based on the activity changes of immunologic and hallmark gene sets in tumor and nontumor tissues.

Jiao Gong, Rong Li, Yaqiong Chen, Zhenjian Zhuo, Shuru Chen, Jing Cao, Qi Zhang, Yutian Chong, Bo Hu,

The prognostic role of adjacent nontumor tissue in hepatocellular carcinoma (HCC) patients is still not clear. The activity changes of immunologic and hallmark gene sets in adjacent nontumor tissues may substantially impact on prognosis by affecting proliferation of liver cells and colonization of circulating tumor cells after HCC treatment measures ... Read more >>

Brief Bioinform (Briefings in bioinformatics)
[2021, :]

Cited: 1 time

View full text PDF listing >>



Activated Hepatic Stellate Cells Induce Infiltration and Formation of CD163+ Macrophages via CCL2/CCR2 Pathway.

Sujuan Xi, Xiaoyan Zheng, Xiangyong Li, Yuming Jiang, Yuankai Wu, Jiao Gong, Yusheng Jie, Zhanyi Li, Jing Cao, Liuping Sha, Min Zhang, Yutian Chong,

<b>Background:</b> Activated hepatic stellate cells (aHSCs) regulate the function of immune cells during liver fibrosis. As major innate cells in the liver, macrophages have inducible plasticity. Nevertheless, the mechanisms through which aHSCs regulate macrophages' phenotype and function during liver fibrosis and cirrhosis remain unclear. In this study, we examined the ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2021, 8:627927]

Cited: 0 times

View full text PDF listing >>



Association between Circulating Growth Differentiation Factor 15 and Cirrhotic Primary Biliary Cholangitis.

Zhanyi Li, Yu Liu, Xiangyong Li, Yuankai Wu, Fangji Yang, Qiwan Mo, Yutian Chong,

Primary biliary cholangitis (PBC) is a common condition that usually shows a progressive course towards cirrhosis without adequate treatment. Growth differentiation factor 15 (GDF15) plays multiple roles in various pathological conditions. The overall role of circulating GDF15 in cirrhotic PBC requires further investigation. Twenty patients with cirrhotic PBC, 26 with ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:5162541]

Cited: 0 times

View full text PDF listing >>



Applying Random Forest Model Algorithm to GFR Estimation

Peijia Liu, Dong Yang, Shaomin Li, Yutian Chong, Wentao Hu, Bohan Wang, Xun Liu,

<h4>Background: </h4> The utilization of estimating-GFR equations is critical for kidney disease in the clinic. However, the performance of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation has not improved substantially in the past eight years. Here we hypothesized that random forest regression(RF) method could go beyond revised linear regression, ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Bayesian network to predict hepatitis B surface antigen seroclearance in chronic hepatitis B patients.

Yun Huang, Xiangyong Li, Xiaoyan Zheng, Xiaolu Tian, Mingxue Yu, Liuping Sha, Yinhui Liu, Yutian Chong, Yuantao Hao, Xu You,

There is a need for an interpretable, accurate and interactions-considered model for predicting hepatitis B surface antigen (HBsAg) seroclearance. We aimed to construct a Bayesian network (BN) model using available medical records to predict HBsAg seroclearance in chronic hepatitis B (CHB) patients, and to evaluate the model's performance. This was ... Read more >>

J Viral Hepat (Journal of viral hepatitis)
[2020, 27(12):1326-1337]

Cited: 0 times

View full text PDF listing >>



A comprehensive analysis of the MAGE family as prognostic and diagnostic markers for hepatocellular carcinoma.

Rong Li, Jiao Gong, Cuicui Xiao, Shuguang Zhu, Zhongying Hu, Jinliang Liang, Xuejiao Li, Xijing Yan, Xijian Zhang, Danyang Li, Wei Liu, Yutian Chong, Yusheng Jie,

The Melanoma Antigen Gene (MAGE) family is a large, highly conserved group of proteins which was reported to participate in the progression of multiple cancers in humans. However, the function of distinct MAGE genes in hepatocellular carcinoma (HCC) is largely unclear. In this study, we comprehensively evaluated the expression, clinical ... Read more >>

Genomics (Genomics)
[2020, 112(6):5101-5114]

Cited: 3 times

View full text PDF listing >>



Upper Respiratory Tract Viral Ribonucleic Acid Load at Hospital Admission Is Associated With Coronavirus Disease 2019 Disease Severity.

Xiaoyan Guo, Yusheng Jie, Yinong Ye, Ping Chen, Xinhua Li, Zhiliang Gao, Ganwen Li, Hong Deng, Yubao Zheng, Bingliang Lin, Yutian Chong, Fengjuan Chen,

<h4>Background</h4>The outbreak of coronavirus disease 2019 (COVID-19) has aroused global public health concerns. Multiple clinical features relating to host profile but not for virus have been identified as the risk factors for illness severity and/or the outcomes in COVID-19.<h4>Methods</h4>The clinical features obtained from a cohort of 195 laboratory-confirmed, nasopharynx-sampled patients ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2020, 7(7):ofaa282]

Cited: 1 time

View full text PDF listing >>



A Comprehensive Analysis of the MAGE Family as Prognostic and Diagnostic Markers for Hepatocellular Carcinoma

Rong Li, Jiao Gong, Cuicui Xiao, Shuguang Zhu, Zhongying Hu, Jinliang Liang, Xuejiao Li, Xijing Yan, Xijian Zhang, Danyang Li, Wei Liu, Yutian Chong, Yusheng Jie,

<h4>Background: </h4> The Melanoma Antigen Gene (MAGE) family is a large, highly conserved group of proteins that share a common MAGE homology domain. Multiple MAGEs are aberrantly expressed in a variety of cancers. However, the function of distinct MAGE genes in hepatocellular carcinoma (HCC) is largely unclear. Our study aimed ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Dysregulation of Circulating FGF19 and Bile Acids in Primary Biliary Cholangitis-Autoimmune Hepatitis Overlap Syndrome.

Zhanyi Li, Yu Liu, Fangji Yang, Jiahui Pang, Yuankai Wu, Yutian Chong, Xiangyong Li,

<h4>Background</h4>Primary biliary cholangitis-autoimmune hepatitis overlap syndrome (PBC-AIH OS), which exhibits features between autoimmune hepatitis and cholestasis, is a common condition and usually shows a progressive course toward cirrhosis and liver failure without adequate treatment. Synthesis of bile acids (BAs) plays an important role in liver injury in cholestasis, and the ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:1934541]

Cited: 0 times

View full text PDF listing >>



NCAPG Is a Promising Therapeutic Target Across Different Tumor Types.

Cuicui Xiao, Jiao Gong, Yusheng Jie, Jing Cao, Zhongcheng Chen, Rong Li, Yutian Chong, Bo Hu, Qi Zhang,

Background:With the advent of CRISPR-Cas9 genome editing tool in gene therapy, identification of aberrantly expressed genes is of great value across various cancer types. Since a large number of patients may benefit from molecular targeted gene therapy. The purpose of this study was to identify aberrantly expressed genes across various ... Read more >>

Front Pharmacol (Frontiers in pharmacology)
[2020, 11:387]

Cited: 2 times

View full text PDF listing >>



Activated Hepatic Stellate Cells Induce Infiltration and Formation of CD163+ Macrophages via CCL2/CCR2 Pathway

Sujuan Xi, Xiaoyan Zheng, Yuming Jiang, Yuankai Wu, Jiao Gong, Yusheng Jie, Xiangyong Li, Jing Cao, Liuping Sha, Min Zhang, Yutian Chong,

<h4>Background: </h4> Growing evidence indicates that activated hepatic stellate cells (aHSCs) play unexpected roles in regulating immune cells’ function during liver fibrosis. Macrophages feature with inducible plasticity according to the circumstances while patrol for potential pathogens. However, studies seldom investigate whether and how the aHSCs regulate the phenotype and function ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Applying Random Forest Model Algorithm to GFR estimation

Peijia Liu, Dong Yang, Shaomin Li, Yutian Chong, Ming Li, Wentao Hu, Bohan Wang, Xiang Liu, Xun Liu,

<h4>Background: </h4> The utilization of estimating-GFR equations is critical for kidney disease in the clinic. However, the performance of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation has not improved substantially in the past eight years. Here we hypothesized that random forest regression(RF) method could go beyond revised linear regression, ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



Deep learning Enables Accurate Diagnosis of Novel Coronavirus (COVID-19) with CT images

Song Ying, Shuangjia Zheng, Liang Li, Xiang Zhang, Xiaodong Zhang, Ziwang Huang, Jianwen Chen, Huiying Zhao, Ruixuan Wang, Yutian Chong, Jun Shen, Yunfei Zha, Yuedong Yang,

<h4>Background</h4> A novel coronavirus (COVID-19) has emerged recently as an acute respiratory syndrome. The outbreak was originally reported in Wuhan, China, but has subsequently been spread world-widely. As the COVID-19 continues to spread rapidly across the world, computed tomography (CT) has become essentially important for fast diagnoses. Thus, it is ... Read more >>

()
[, :]

Cited: 5 times

View full text PDF listing >>



DGAT-onco: A powerful method to detect oncogenes by integrating differential mutational analysis and functional impacts of somatic mutations

Haoyang Zhang, Junkang Wei, Zifeng Liu, Xun Liu, Yutian Chong, Yutong Lu, Huiying Zhao, Yuedong Yang,

<h4>Motivation</h4> Oncogenes are genes whose malfunctions play critical roles in cancer development, and their discovery is a major aim of cancer mechanisms study. By counting the mutation frequency, oncogenes have been identified with frequent mutations, while it is believed that many more oncogenes could be discovered by differential mutational profile ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



To Improve Protein Sequence Profile Prediction through Image Captioning on Pairwise Residue Distance Map.

Sheng Chen, Zhe Sun, Lihua Lin, Zifeng Liu, Xun Liu, Yutian Chong, Yutong Lu, Huiying Zhao, Yuedong Yang,

Protein sequence profile prediction aims to generate multiple sequences from structural information to advance the protein design. Protein sequence profile can be computationally predicted by energy-based or fragment-based methods. By integrating these methods with neural networks, our previous method, SPIN2, has achieved a sequence recovery rate of 34%. However, SPIN2 ... Read more >>

J Chem Inf Model (Journal of chemical information and modeling)
[2020, 60(1):391-399]

Cited: 1 time

View full text PDF listing >>



Fluconazole plus flucytosine is a good alternative therapy for non-HIV and non-transplant-associated cryptococcal meningitis: A retrospective cohort study.

Zhanyi Li, Yu Liu, Yutian Chong, Xiangyong Li, Yusheng Jie, Xiaoyan Zheng, Ying Yan,

Cryptococcal meningitis (CM) carries a high risk of mortality with increasing incidences in immune competent hosts. Current treatments are not well tolerated, and evaluation of other treatments is needed. Fluconazole and 5-flucytosine in treating immune competent hosts have not been characterised. To evaluate the efficacy of fluconazole and 5-flucytosine in ... Read more >>

Mycoses (Mycoses)
[2019, 62(8):686-691]

Cited: 1 time

View full text PDF listing >>



To Improve Protein Sequence Profile Prediction through Image Captioning on Pairwise Residue Distance Map

Sheng Chen, Zhe Sun, Zifeng Liu, Xun Liu, Yutian Chong, Yutong Lu, Huiying Zhao, Yuedong Yang,

<h4>ABSTRACT</h4> Protein sequence profile prediction aims to generate multiple sequences from structural information to advance the protein design. Protein sequence profile can be computationally predicted by energy-based method or fragment-based methods. By integrating these methods with neural networks, our previous method, SPIN2 has achieved a sequence recovery rate of 34%. ... Read more >>

()
[, :]

Cited: 0 times

View full text PDF listing >>



The clinical value of Fibulin-1 for prognosis and its prospective mechanism in intrahepatic cholangiocarcinoma.

Yusheng Jie, Jiao Gong, Cuicui Xiao, Jun Zheng, Zhiwei Zhang, Xinhua Li, Zhiliang Gao, Bo Hu, Yutian Chong,

<h4>Background</h4>Intrahepatic cholangiocarcinoma (ICC) is the second most common malignancy arising from the liver. Fibulin-1 has been demonstrated to be involved in various cancers, however, its role in ICC remains unclear.<h4>Methods</h4>To study the clinical value and potential molecular mechanism of Fibulin-1 in ICC, immunohistochemistry and bioinformatic analyses were performed using data ... Read more >>

HPB (Oxford) (HPB : the official journal of the International Hepato Pancreato Biliary Association)
[2019, 21(4):499-507]

Cited: 2 times

View full text PDF listing >>



Naturally Occurring Resistance-Associated Variants to Hepatitis C Virus Direct-Acting Antiviral Agents in Treatment-Naive HCV Genotype 6a-Infected Patients.

Zhanyi Li, Ying Liu, Ying Zhang, Xiaoqiong Shao, Qiumin Luo, Xiaoyan Guo, Guoli Lin, Qingxian Cai, Zhixin Zhao, Yutian Chong,

<h4>Background and objective</h4>The direct-acting antiviral agents (DAAs) antiviral therapy has drastically improved the prognosis of hepatitis C virus (HCV) patients. However, the viral drug resistance-associated variants (RAVs) can limit the efficacy of DAAs. For the HCV-6a is not the predominant prevalent genotype; the data on the prevalence of naturally occurring ... Read more >>

Biomed Res Int (BioMed research international)
[2017, 2017:9849823]

Cited: 5 times

View full text PDF listing >>



Advertisement

Disclaimer
1.1561 s