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Author Yushan Li

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A longitudinal study of semen quality among Chinese sperm donor candidates during the past 11 years.

Junjie Liu, Yanpeng Dai, Yushan Li, Enwu Yuan, Quanxian Wang, Xingling Wang, Yichun Guan,

Studies suggest that semen quality is declining globally, however, the debate remains open due to the possible effects of ethnic and geographical differences. This study aimed to explore whether semen quality of sperm donor candidates has changed in Henan Province, China from 2009 to 2019. In this retrospective study, we ... Read more >>

Sci Rep (Scientific reports)
[2020, 10(1):10771]

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Regulation of laryngeal squamous cell cancer progression by the lncRNA RP11-159K7.2/miR-206/DNMT3A axis.

Xin Wang, Boyu Yu, Qianqian Jin, Junyi Zhang, Bingrui Yan, Like Yang, Yushan Li, Qiuying Li, Peng Wang, Chuanhui Sun, Ming Liu, Linli Tian, Yanan Sun,

Long non-coding RNAs (lncRNAs), which are longer than 200 nt, have been proved to play a role in promoting or inhibiting cancer progression. The following study investigated the role and underlying mechanisms of lncRNA RP11-159K7.2 in laryngeal squamous cell carcinoma (LSCC) progression. Briefly, in situ hybridization (ISH) and real-time quantitative ... Read more >>

J. Cell. Mol. Med. (Journal of cellular and molecular medicine)
[2020, 24(12):6781-6795]

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LncRNA MSC-AS1 aggravates nasopharyngeal carcinoma progression by targeting miR-524-5p/nuclear receptor subfamily 4 group A member 2 (NR4A2).

Hongchao Yao, Like Yang, Linli Tian, Yan Guo, Yushan Li,

Background:Nasopharyngeal carcinoma (NPC) is a subtype of head and neck cancer with dismal prognosis and high relapse rate. The role of long non-coding RNAs (lncRNAs) in NPC has become a research hotspot in recent years. This study aimed to interrogate the function and mechanism of lncRNA MSC antisense RNA 1 ... Read more >>

Cancer Cell Int. (Cancer cell international)
[2020, 20:138]

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Selenium enhances iron plaque formation by elevating the radial oxygen loss of roots to reduce cadmium accumulation in rice (Oryza sativa L.).

Gaoxiang Huang, Changfeng Ding, Yushan Li, Taolin Zhang, Xingxiang Wang,

The inhibition of cadmium (Cd) absorption by selenium (Se) in rice may be associated with iron plaque (IP) formation, but the driving mechanisms are still unclear. This study investigated the effects of Se on the growth, oxidative toxicity, radial oxygen loss (ROL), IP formation, and Cd absorption of rice exposed ... Read more >>

J. Hazard. Mater. (Journal of hazardous materials)
[2020, 398:122860]

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Analysis of the women with the AMH concentrations below the limit of reference range but with the ideal number of retrieved oocytes.

Wenbin Wu, Xingling Wang, Yushan Li, Yuchao Zhang,

PURPOSE:Serum anti-Mullerian hormone (AMH) shows a strong positive correlation to the number of oocytes retrieved but the patients undergoing assisted reproductive technology (ART) with lower AMH concentrations also could retrieve an ideal number of oocytes sometimes. The aim of the current study was to assess the performance of this population. METHODS:This ... Read more >>

Arch. Gynecol. Obstet. (Archives of gynecology and obstetrics)
[2020, 301(4):1089-1094]

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Male fertility in Mus musculus requires the activity of TRYX5 in sperm migration into the oviduct.

Haihang Zhang, Yushan Li, Kuiqing Cui, Xiu Chen, Cuiling Shang, Wanping Min, Peng Jin, Zhaodi Jiang, Deshun Shi, Qingyou Liu, Fengchao Wang,

Nowadays, abnormal loss of serine proteases appears very frequently in male patients with unexplained sterility. In fact, many testis-specific serine proteases, the largest family among the four protease families implicated in murine spermatogenesis, are indispensable for reproduction. In the present study, we demonstrate that the previously uncharacterized testis-specific serine protease ... Read more >>

J. Cell. Physiol. (Journal of cellular physiology)
[2020, 235(9):6058-6072]

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Long noncoding RNA Mirt2 prohibits lipopolysaccharide-evoked HK-2 cell injury via modulation of microRNA-126.

Cui Bai, Nana Nie, Yushan Li, Chong Zhang, Min Xu, Zipu Li,

Long noncoding RNA myocardial infarction-associated transcript 2 (lncRNA Mirt2) is a burgeoning lncRNA, its anti-inflammatory capacity has been testified. Nonetheless, the functions of Mirt2 in immunoglobulin A nephropathy are unexplored. We tried to impart the influences of Mirt2 in lipopolysaccharide (LPS)-evoked HK-2 cells damage. HK-2 cells were manipulated with 10 ... Read more >>

Biofactors (BioFactors (Oxford, England))
[2020, 46(3):465-474]

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Age-specific and sex-specific reference intervals for non-fasting lipids and apolipoproteins in 7260 healthy Chinese children and adolescents measured with an Olympus AU5400 analyser: a cross-sectional study.

Junjie Liu, Yanpeng Dai, Enwu Yuan, Yushan Li, Quanxian Wang, Linkai Wang, Yanhua Su,

AIMS:Ethnic, demographic, lifestyle, genetic and environmental factors influence lipids and apolipoproteins. The aim of this study was to establish age-specific and gender-specific reference intervals for non-fasting lipids and apolipoproteins in healthy Chinese children and adolescents. METHODS:This study followed the Clinical and Laboratory Standards Institute EP28-A3c guidelines. Non-fasting samples were collected ... Read more >>

BMJ Open (BMJ open)
[2019, 9(8):e030201]

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Paediatric reference intervals for common coagulation assays in Chinese children as performed on the STA-R coagulation analyzer.

Junjie Liu, Yanpeng Dai, Enwu Yuan, Yushan Li, Quanxian Wang, Linkai Wang, Yanhua Su,

INTRODUCTION:In order to correctly manage the paediatric patients affected with haemostatic disorders, age-appropriate reference intervals should be used. The purpose of this study was to establish age-specific reference intervals for prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (aPTT) and fibrinogen (Fg). METHODS:In this study, a total of ... Read more >>

Int J Lab Hematol (International journal of laboratory hematology)
[2019, 41(5):697-701]

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Research on Lane a Compensation Method Based on Multi-Sensor Fusion.

Yushan Li, Wenbo Zhang, Xuewu Ji, Chuanxiang Ren, Jian Wu,

The curvature of the lane output by the vision sensor caused by shadows, changes in lighting and line breaking jumps over in a period of time, which leads to serious problems for unmanned driving control. It is particularly important to predict or compensate the real lane in real-time during sensor ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2019, 19(7):]

Cited: 1 time

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A Novel LncRNA, AC091729.7 Promotes Sinonasal Squamous Cell Carcinomas Proliferation and Invasion Through Binding SRSF2.

Boyu Yu, Linmei Qu, Tianyi Wu, Bingrui Yan, Xuan Kan, Xuehui Zhao, Like Yang, Yushan Li, Ming Liu, Linli Tian, Yanan Sun, Qiuying Li,

Long non-coding RNAs (lncRNAs) play important roles in various biological progresses of carcinogenesis. However, the function of lncRNAs in human sinonasal squamous cell carcinoma (SNSCC) remains greatly unclear. In the current study, lncRNA AC091729.7 expression was examined in SNSCC samples by using microarray, RNA in situ hybridization (ISH) and real-time ... Read more >>

Front Oncol (Frontiers in oncology)
[2019, 9:1575]

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Intestinal probiotics restore the ecological fitness decline of Bactrocera dorsalis by irradiation.

Zhaohui Cai, Zhichao Yao, Yushan Li, Zhiyong Xi, Kostas Bourtzis, Zheng Zhao, Shuai Bai, Hongyu Zhang,

The sterile insect technique (SIT) as an eco-friendly and reliable strategy has been used to control populations of insect pests of agricultural, veterinary and human health importance. Successful applications of SIT rely on the high-level ecological fitness of sterile males. A suitable and stable gut microbiome can contribute to the ... Read more >>

Evol Appl (Evolutionary Applications)
[2018, 11(10):1946-1963]

Cited: 3 times

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"Same difference": comprehensive evaluation of four DNA methylation measurement platforms.

Thadeous J Kacmarczyk, Mame P Fall, Xihui Zhang, Yuan Xin, Yushan Li, Alicia Alonso, Doron Betel,

BACKGROUND:DNA methylation in CpG context is fundamental to the epigenetic regulation of gene expression in higher eukaryotes. Changes in methylation patterns are implicated in many diseases, cellular differentiation, imprinting, and other biological processes. Techniques that enrich for biologically relevant genomic regions with high CpG content are desired, since, depending on ... Read more >>

Epigenetics Chromatin (Epigenetics & chromatin)
[2018, 11(1):21]

Cited: 1 time

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Expression of long non-coding RNA HOXA11-AS is correlated with progression of laryngeal squamous cell carcinoma.

Lingmei Qu, Meng Jin, Like Yang, Chuanhui Sun, Peng Wang, Yushan Li, Linli Tian, Ming Liu, Yanan Sun,

Long noncoding RNA HOXA11 antisense RNA (HOXA11-AS) is involved in tumorigenesis and development of some human cancers. However, the role of HOXA11-AS in human laryngeal squamous cell cancer (LSCC) is yet unclear. In this study, we firstly investigated the expression of HOXA11-AS in LSCC. Microarray and qRT-PCR showed that the ... Read more >>

Am J Transl Res (American journal of translational research)
[2018, 10(2):573-580]

Cited: 6 times

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Gestational age-specific reference intervals for 15 biochemical measurands during normal pregnancy in China.

Yanpeng Dai, Junjie Liu, Enwu Yuan, Yushan Li, Quanxian Wang, Liting Jia, Linkai Wang, Yanhua Su,

Aims Physiological changes that occur during pregnancy can influence biochemical parameters. Therefore, using reference intervals based on specimens from non-pregnant women to interpret laboratory results during pregnancy may be inappropriate. This study aimed to establish the essential reference intervals for a range of analytes during pregnancy. Methods A cross-sectional study ... Read more >>

Ann. Clin. Biochem. (Annals of clinical biochemistry)
[2018, 55(4):446-452]

Cited: 1 time

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"Same Difference": Comprehensive evaluation of three DNA methylation measurement platforms

Thadeous Kacmarczyk, Mame Fall, Xihui Zhang, Yuan Xin, Yushan Li, Alicia Alonso, Doron Betel,

ABSTRACT Background DNA methylation in CpG context is fundamental to the epigenetic regulation of gene expression in high eukaryotes. Disorganization of methylation status is implicated in many diseases, cellular differentiation, imprinting, and other biological processes. Techniques that enrich for biologically relevant genomic regions with high CpG content are desired, since, ... Read more >>

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[Pathogenic Analyses of an Outbreak of Viral Encephalitis Caused by ECHO30 in Guazhou of Gansu Province, China].

Jianhua Chen, Zhen Zhu, Yushan Li, Haizhuo Wu, Haixia Liu, Xuxia Wang, Deshan Yu,

We used molecular-biology methods to identify the pathogens that caused an outbreak of viral encephalitis in Guazhou (Gansu province, China)during June-August 2015.We also undertook molecular characterizations of these pathogens. A total of 132samples(14cerebrospinal fluid(CSF)samples;25throat swabs;66serum samples;27fecal samples)were collected from 74 patients during the outbreak of viral encephalitis. For CSF and ... Read more >>

Bing Du Xue Bao (Bing du xue bao = Chinese journal of virology)
[2016, 32(6):721-726]

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The dual oxidase gene BdDuox regulates the intestinal bacterial community homeostasis of Bactrocera dorsalis.

Zhichao Yao, Ailin Wang, Yushan Li, Zhaohui Cai, Bruno Lemaitre, Hongyu Zhang,

The guts of metazoans are in permanent contact with the microbial realm that includes beneficial symbionts, nonsymbionts, food-borne microbes and life-threatening pathogens. However, little is known concerning how host immunity affects gut bacterial community. Here, we analyze the role of a dual oxidase gene (BdDuox) in regulating the intestinal bacterial ... Read more >>

ISME J (The ISME journal)
[2016, 10(5):1037-1050]

Cited: 13 times

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High Genetic Diversity of Microbial Cellulase and Hemicellulase Genes in the Hindgut of Holotrichia parallela Larvae.

Ping Sheng, Yushan Li, Sean D G Marshall, Hongyu Zhang,

In this study, we used a culture-independent method based on library construction and sequencing to analyze the genetic diversity of the cellulase and hemicellulase genes of the bacterial community resident in the hindgut of Holotrichia parallela larvae. The results indicate that there is a large, diverse set of bacterial genes ... Read more >>

Int J Mol Sci (International journal of molecular sciences)
[2015, 16(7):16545-16559]

Cited: 4 times

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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.

Raajit Rampal, Altuna Alkalin, Jozef Madzo, Aparna Vasanthakumar, Elodie Pronier, Jay Patel, Yushan Li, Jihae Ahn, Omar Abdel-Wahab, Alan Shih, Chao Lu, Patrick S Ward, Jennifer J Tsai, Todd Hricik, Valeria Tosello, Jacob E Tallman, Xinyang Zhao, Danette Daniels, Qing Dai, Luisa Ciminio, Iannis Aifantis, Chuan He, Francois Fuks, Martin S Tallman, Adolfo Ferrando, Stephen Nimer, Elisabeth Paietta, Craig B Thompson, Jonathan D Licht, Christopher E Mason, Lucy A Godley, Ari Melnick, Maria E Figueroa, Ross L Levine,

Somatic mutations in IDH1/IDH2 and TET2 result in impaired TET2-mediated conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). The observation that WT1 inactivating mutations anticorrelate with TET2/IDH1/IDH2 mutations in acute myeloid leukemia (AML) led us to hypothesize that WT1 mutations may impact TET2 function. WT1 mutant AML patients have reduced 5hmC ... Read more >>

Cell Rep (Cell reports)
[2014, 9(5):1841-1855]

Cited: 90 times

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LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice.

Juan Chen, Rui Fu, Yan Cui, Jirong Pan, Yushan Li, Xiaoxin Zhang, Sylvia M Evans, Sheng Cui, Jiali Liu,

Kisspeptin and the G protein-coupled receptor 54 (GPR54) are highly abundant in the pancreas. In addition, circulating kisspeptin directly influences insulin secretion through GPR54. However, the mechanisms by which kisspeptin affects insulin release are unclear. The LIM-homeodomain transcription factor, Isl-1, is expressed in all pancreatic islet cells and is involved ... Read more >>

Mol. Endocrinol. (Molecular endocrinology (Baltimore, Md.))
[2014, 28(8):1276-1290]

Cited: 4 times

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LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3.

Yushan Li, Jirong Pan, Chao Wei, Juan Chen, Ying Liu, Jiali Liu, Xiaoxin Zhang, Sylvia M Evans, Yan Cui, Sheng Cui,

Abnormalities in pyloric development or in contractile function of the pylorus cause reflux of duodenal contents into the stomach and increase the risk of gastric metaplasia and cancer. Abnormalities of the pyloric region are also linked to congenital defects such as the relatively common neonatal hypertrophic pyloric stenosis, and primary ... Read more >>

BMC Biol. (BMC biology)
[2014, 12:25]

Cited: 9 times

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Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia.

Maria E Figueroa, Shann-Ching Chen, Anna K Andersson, Letha A Phillips, Yushan Li, Jason Sotzen, Mondira Kundu, James R Downing, Ari Melnick, Charles G Mullighan,

Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy and is characterized by recurring structural genetic alterations. Previous studies of DNA methylation suggest epigenetic alterations may also be important, but an integrated genome-wide analysis of genetic and epigenetic alterations in ALL has not been performed. We analyzed 137 B-lineage and ... Read more >>

J. Clin. Invest. (The Journal of clinical investigation)
[2013, 123(7):3099-3111]

Cited: 57 times

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ZnO nanorod array-coated mesh film for the separation of water and oil.

Hong Li, Yushan Li, Qinzhuang Liu,

Dense and vertically aligned ZnO nanorod arrays with a large area have been fabricated successfully on the stainless steel mesh by a simple chemical vapor deposition method. The coated mesh exhibited both superoleophilic and superhydrophobic properties, even if it was not modified by low surface energy materials. The separation efficiencies ... Read more >>

Nanoscale Res Lett (Nanoscale research letters)
[2013, 8(1):183]

Cited: 3 times

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[Trace chemical constituents contained in Trachelospermum jasminoides and structure identification].

Ling Jing, Nengjiang Yu, Yimin Zhao, Yushan Li,

OBJECTIVE: To study trace chemical constituents contained in traditional Chinese medicine Trachelospermum jasminoides. METHOD: The chemical constituents were separated and purified by using such column chromatographic methods as ployamide, silica gel, Sephadex LH-20 and ODS, and their structures were identified on the basis of spectral data analysis. RESULT: Eleven compounds ... Read more >>

Zhongguo Zhong Yao Za Zhi (Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica)
[2012, 37(11):1581-1585]

Cited: 1 time

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