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In vivo kinematics of deep lunges and sit-to-stand activities in patients with bicruciate-retaining total knee arthroplasty.

Young-Min Kwon, Paul Arauz, Yun Peng, Christian Klemt,

AIMS:The removal of the cruciate ligaments in total knee arthroplasty (TKA) has been suggested as a potential contributing factor to patient dissatisfaction, due to alteration of the in vivo biomechanics of the knee. Bicruciate retaining (BCR) TKA allows the preservation of the cruciate ligaments, thus offering the potential to reproduce ... Read more >>

Bone Joint J (The Bone & Joint Journal)
[2020, 102-B(6_Supple_A):59-65]

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Grade Prediction of Bleeding Volume in Cesarean Section of Patients With Pernicious Placenta Previa Based on Deep Learning.

Jun Liu, Tao Wu, Yun Peng, Rongguang Luo,

In order to predict the amount of bleeding in the cesarean section of the patients with Pernicious Placenta Previa (PPP), this study proposed an automatic blood loss prediction method based on Magnetic Resonance Imaging (MRI) uterus image. Firstly, the DeepLab-V3 + network was used to segment the original MRI abdominal ... Read more >>

Front Bioeng Biotechnol (Frontiers in bioengineering and biotechnology)
[2020, 8:343]

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In Vitro Kinematic Analysis of Single Axis Radius Posterior-Substituting Total Knee Arthroplasty.

Paul Arauz, Yun Peng, Tiffany Castillo, Christian Klemt, Young-Min Kwon,

This is an experimental study. As current posterior-substituting (PS) total knee arthroplasties have been reported to incompletely restore intrinsic joint biomechanics of the healthy knee, the recently designed single axis radius PS knee system was introduced to increase posterior femoral translation and promote ligament isometry. As there is a paucity ... Read more >>

J Knee Surg (The journal of knee surgery)
[2020, :]

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Performance evaluation of two iterative reconstruction algorithms, MBIR and ASIR, in low radiation dose and low contrast dose abdominal CT in children.

Jihang Sun, Lixin Yang, Zuofu Zhou, Dan Zhang, Wei Han, Qifeng Zhang, Yun Peng,

BACKGROUND:The adverse effect of low-dose CT on image quality may be mitigated using iterative reconstructions. The purpose of this study was to evaluate the performance of the full model-based iterative reconstruction (MBIR) and adaptive statistical reconstruction (ASIR) algorithms in low radiation dose and low contrast dose abdominal contrast-enhanced CT (CECT) ... Read more >>

Radiol Med (La Radiologia medica)
[2020, :]

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Differential White Matter Maturation from Birth to 8 Years of Age.

Qinlin Yu, Yun Peng, Huiying Kang, Qinmu Peng, Minhui Ouyang, Michelle Slinger, Di Hu, Haochang Shou, Fang Fang, Hao Huang,

Comprehensive delineation of white matter (WM) microstructural maturation from birth to childhood is critical for understanding spatiotemporally differential circuit formation. Without a relatively large sample of datasets and coverage of critical developmental periods of both infancy and early childhood, differential maturational charts across WM tracts cannot be delineated. With diffusion ... Read more >>

Cereb. Cortex (Cerebral cortex (New York, N.Y. : 1991))
[2020, 30(4):2673-2689]

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Corrigendum to "Profiling of mitochondrial genomes in SCA3/MJD patients from mainland China" [Gene 738 (2020) 144487].

Hongyu Yuan, Huihua Yang, Linliu Peng, Yun Peng, Zhao Chen, Linlin Wan, Chunrong Wang, Yuting Shi, Victor Wei Zhang, Beisha Tang, Rong Qiu, Hong Jiang,

Gene (Gene)
[2020, 740:144607]

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Clinical Characteristics of Secondary Immune Thrombocytopenia Associated With Primary Sjögren's Syndrome.

Fan Dai, Guomei Yang, Peishi Rao, Puqi Wu, Rongjuan Chen, Yuechi Sun, Yun Peng, Hongyan Qian, Bin Wang, Shiju Chen, Yuan Liu, Guixiu Shi,

Objective: Clinical characteristics of immune thrombocytopenia (ITP) associated with primary Sjögren's syndrome (pSS) have not been clearly defined. This study aimed to evaluate the prevalence and clinical characteristics of secondary ITP in patients with pSS. Methods: 291 pSS patients in our hospital were retrospectively analyzed. Clinical manifestations and laboratory findings ... Read more >>

Front Med (Lausanne) (Frontiers in medicine)
[2020, 7:138]

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Arabidopsis V-ATPase d2 subunit plays a role in plant responses to oxidative stress

Shuang Feng, Yun Peng, Enhui Liu, Hongping Ma, Kun Qiao, Aimin Zhou, Shenkui Liu, Yuanyuan Bu,

Abstract Background : Vacuolar-type H + -ATPase (V-ATPase) is a multisubunit proton pump located on the endomembranes, which plays an important role in plant growth. The Arabidopsis V-ATPase d subunit consists of two isoforms, AtVHA-d1 and AtVHA-d2. Results: In this study, the function of the AtVHA-d2 gene was investigated. Histochemical ... Read more >>

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Involvement of the JNK signaling in granular corneal dystrophy by modulating TGF-β-induced TGFBI expression and corneal fibroblast apoptosis.

Danyao Nie, Xinhua Liu, Yuan Wang, Wenling He, Ming Li, Yun Peng, Jing Zhang, Liangnan Sun, Zonghui Yan, Lin Ye,

Granular corneal dystrophy (GCD) is featured by corneal deposits of transforming growth factor beta-induced gene (TGFBI) mediated by the TGF-β (transforming growth factor-β)/Smad signaling. However, the roles of c-Jun amino-terminal kinase (JNK) pathway in GCD pathogenesis remains unexplored, which was investigated in this study. JNK signaling activation and inhibition in ... Read more >>

In Vitro Cell. Dev. Biol. Anim. (In vitro cellular & developmental biology. Animal)
[2020, 56(3):234-242]

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A prognostic nomogram based on competing endogenous RNA network for clear-cell renal cell carcinoma

Yun Peng, Shangrong Wu, Zihan Xu, Dingkun Hou, Nan Li, Zheyu Zhang, Lili Wang, Yangyi Zhang, Haitao Wang,

Abstract Backgroud Clear-cell renal cell carcinoma (ccRCC) is stubborn to traditional chemotherapy and radiation treatment, which makes its clinical management a major challenge. Recently, we have made efforts to understand the etiology of ccRCC. Increasing evidence revealed that the competing endogenous RNA (ceRNA) were involved in the development of various ... Read more >>

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Relationships of Stresses on Alveolar Bone and Abutment of Dental Implant from Various Bite Forces by Three-Dimensional Finite Element Analysis.

Xiaoning Kang, Yiming Li, Yixi Wang, Yao Zhang, Dongsheng Yu, Yun Peng,

Occlusal trauma caused by improper bite forces owing to the lack of periodontal membrane may lead to bone resorption, which is still a problem for the success of dental implant. In our study, to avoid occlusal trauma, we put forward a hypothesis that a microelectromechanical system (MEMS) pressure sensor is ... Read more >>

Biomed Res Int (BioMed research international)
[2020, 2020:7539628]

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Effects of Grape Seed Proanthocyanidin Extract on Obesity.

Miao Liu, Peng Yun, Ying Hu, Jiao Yang, Rim Bahadur Khadka, Xiaochun Peng,

Obesity is a chronic metabolic disease resulting from excessive fat accumulation and/or abnormal distribution caused by multiple factors. As a major component of metabolic syndrome, obesity is closely related to many diseases such as type 2 diabetes mellitus, hyperlipidemia, hypertension, coronary heart disease, stroke and cancer. Hence, the problem of ... Read more >>

Obes Facts (Obesity facts)
[2020, 13(2):279-291]

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Development of Brain Structural Networks Over Age 8: A Preliminary Study Based on Diffusion Weighted Imaging.

Zhanxiong Wu, Yun Peng, Sudhakar Selvaraj, Paul E Schulz, Yingchun Zhang,

Brain structural network changes provide key information about the aging process of the brain. Unfortunately, there has yet to be a detailed characterization of these structural networks across different age groups. Efforts to classify these networks have also been hampered by their reliance on technically limited traditional methods, which are ... Read more >>

Front Aging Neurosci (Frontiers in aging neuroscience)
[2020, 12:61]

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Profiling of mitochondrial genomes in SCA3/MJD patients from mainland China.

Hongyu Yuan, Huihua Yang, Linliu Peng, Yun Peng, Zhao Chen, Linlin Wan, Chunrong Wang, Yuting Shi, Victor Wei Zhang, Beisha Tang, Rong Qiu, Hong Jiang,

Spinocerebellar ataxia type 3, also known as Machado-Joseph disease (SCA3/MJD), is the most common type of autosomal dominant cerebellar ataxias. Few studies focused on the changes of the whole mitochondrial genomes of SCA3/MJD patients and its relationship with the pathogenesis of SCA3/MJD. We adapted one-step long-range PCR to amplify the ... Read more >>

Gene (Gene)
[2020, 738:144487]

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The influence of common component on myoelectric pattern recognition.

Bo Yao, Yun Peng, Xu Zhang, Yingchun Zhang, Ping Zhou, Jiangbo Pu,

J. Int. Med. Res. (The Journal of international medical research)
[2020, 48(3):300060520903617]

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Infection with Novel Coronavirus (SARS-CoV-2) Causes Pneumonia in the Rhesus Macaques

Chao Shan, Yan-Feng Yao, Xing-Lou Yang, Yi-Wu Zhou, Jia Wu, Ge Gao, Yun Peng, Lian Yang, Xue Hu, Jin Xiong, Ren-Di Jiang, Hua-Jun Zhang, Xiao-Xiao Gao, Cheng Peng, Juan Min, Ying Chen, Hao-Rui Si, Peng Zhou, Yan-Yi Wang, Hong-Ping Wei, Wei Pang, Zheng-Fei Hu, Long-Bao Lv, Yong-Tang Zheng, Zheng-Li Shi, Zhi-Ming Yuan,

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Corrigendum: Alterations of the Gut Microbiota in Multiple System Atrophy Patients.

Linlin Wan, Xin Zhou, Chunrong Wang, Zhao Chen, Huirong Peng, Xuan Hou, Yun Peng, Puzhi Wang, Tianjiao Li, Hongyu Yuan, Yuting Shi, Xiaocan Hou, Keqin Xu, Yue Xie, Lang He, Kun Xia, Beisha Tang, Hong Jiang,

[This corrects the article DOI: 10.3389/fnins.2019.01102.]. ... Read more >>

Front Neurosci (Frontiers in neuroscience)
[2020, 14:19]

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FKBP51 induces p53-dependent apoptosis and enhances drug sensitivity of human non-small-cell lung cancer cells.

Yu Chen, Zhiqiang Liu, Yuequn Wang, Jian Zhuang, Yun Peng, Xiaoyang Mo, Jimei Chen, Yan Shi, Mengxiong Yu, Wanwan Cai, Yahuan Li, Xiaolan Zhu, Wuzhou Yuan, Yongqing Li, Fang Li, Zuoqiong Zhou, Guo Dai, Xiangli Ye, Yongqi Wan, Zhigang Jiang, Ping Zhu, Xiongwei Fan, Xiushan Wu,

Lung cancer is one of the most prevalent cancer types worldwide, and non-small-cell lung cancer (NSCLC) accounts for ~85% of all lung cancer cases. Despite the notable prevalence of NSCLC, the mechanisms underlying its progression remain unclear. The present study investigated the involvement of FK506-binding protein 51 (FKBP51) in NSCLC ... Read more >>

Exp Ther Med (Experimental and therapeutic medicine)
[2020, 19(3):2236-2242]

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Knockdown of MALAT1 attenuates high-glucose-induced angiogenesis and inflammation via endoplasmic reticulum stress in human retinal vascular endothelial cells.

Yuan Wang, Ling Wang, Hui Guo, Yun Peng, Danyao Nie, Jinsong Mo, Lin Ye,

Diabetic retinopathy (DR) is one of the most severe complications of diabetes mellitus, and retinal endoplasmic reticulum stress (ERS) plays an important role in the pathogenesis of DR. However, the exact mechanisms by which ERS mediates DR remain unclear. In this study, human retinal vascular endothelial cells (RVECs) were cultured ... Read more >>

Biomed. Pharmacother. (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie)
[2020, 124:109699]

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Gender-specific difference of in-vivo kinematics in patients with unilateral total hip arthroplasty.

Yun Peng, Paul Arauz, Young-Min Kwon,

PURPOSE:Asymmetric gait patterns are known to persist in patients with unilateral total hip arthroplasty (THA). Little is known about the effect of gender on gait asymmetry. This study aimed to determine whether gait asymmetry differs between genders in unilateral THA patients and can be explained by component positioning. METHODS:23 female ... Read more >>

Hip Int (Hip international : the journal of clinical and experimental research on hip pathology and therapy)
[2020, :1120700020903498]

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Do magnetic resonance imaging manifestations of skeletal system improve after treatment of Gaucher disease?

Di Li, Xiaojuan Tao, Ningning Zhang, Aihua Huo, Huiying Kang, Chen Xu, Yonghong Zhang, Yun Peng,

OBJECTIVES:Skeletal lesions are the most serious complications of Gaucher disease (GD). The pathological changes of skeletal system are complex, which seriously affects the quality of life. The aim was to investigate whether the skeletal system improved in quantitative imaging after treatment with enzyme replacement therapy (ERT). METHODS:Magnetic resonance imaging (MRI) ... Read more >>

Eur J Radiol (European journal of radiology)
[2020, 125:108851]

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The effect of structural parameters of total hip arthroplasty on polyethylene liner wear behavior: A theoretical model analysis.

Guoan Li, Yun Peng, Chaochao Zhou, Zhongmin Jin, Hany Bedair,

Using large femoral heads in total hip arthroplasty (THA) has been widely advocated to improve the function and longevity of the components. However, increasing the head size has been shown to accelerate polyethylene liner wear. Few studies have investigated the effect of other important structural parameters (such as polyethylene liner ... Read more >>

J. Orthop. Res. (Journal of orthopaedic research : official publication of the Orthopaedic Research Society)
[2019, :]

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Myosin X interaction with KIF13B, a crucial pathway for Netrin-1-induced axonal development

Hua-Li Yu, Yun Peng, Yang Zhao, Yong-Sheng Lan, Bo Wang, Lu Zhao, Dong Sun, Jin-Xiu Pan, Zhao-Qi Dong, Lin Mei, Yu-Qiang Ding, Xiao-Juan Zhu, Wen-Cheng Xiong,

ABSTRACT Myosin X (Myo X) transports cargos to the tip of filopodia for cell adhesion, migration, and neuronal axon guidance. Deleted in Colorectal Cancer (DCC) is one of Myo X cargos essential for Netrin-1-regulated axon pathfinding. Myo X’s function in axon development in vivo and the underlying mechanisms remain poorly ... Read more >>

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STING-Associated Vasculopathy with Onset in Infancy in Three Children with New Clinical Aspect and Unsatisfactory Therapeutic Responses to Tofacitinib.

Xiaolei Tang, Hui Xu, Chunju Zhou, Yun Peng, Hui Liu, Jinrong Liu, Huimin Li, Haiming Yang, Shunying Zhao,

PURPOSE:STING-associated vasculopathy with onset in infancy (SAVI) is a new rare auto-inflammatory disease. The purpose of this study is to report new cases and summarize the manifestations and outcome of SAVI. METHODS:We made a retrospective analysis of three pediatric patients diagnosed with SAVI between March 2016 and July 2018 in ... Read more >>

J. Clin. Immunol. (Journal of clinical immunology)
[2020, 40(1):114-122]

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A genome-wide association study of reproduction traits in four pig populations with different genetic backgrounds.

Jiang Yao, Tang Shao Qing, Xiao Wei, Yun Peng, Ding Xiang Dong,

Objective:Genome-wide association study and two meta-analysis based on GWAS performed to explore the genetic mechanism underlying variation in pig number born alive (NBA) and total number born (TNB). Methods:Single trait GWAS and two meta-analysis (single-trait meta analysis and multi-trait meta analysis) were used in our study for NBA and TNB ... Read more >>

Asian-australas. J. Anim. Sci. (Asian-Australasian journal of animal sciences)
[2019, :]

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