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MFI-Net: A multi-resolution fusion input network for retinal vessel segmentation.

Yun Jiang, Chao Wu, Ge Wang, Hui-Xia Yao, Wen-Huan Liu,

Segmentation of retinal vessels is important for doctors to diagnose some diseases. The segmentation accuracy of retinal vessels can be effectively improved by using deep learning methods. However, most of the existing methods are incomplete for shallow feature extraction, and some superficial features are lost, resulting in blurred vessel boundaries ... Read more >>

PLoS One (PloS one)
[2021, 16(7):e0253056]

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Regulations and Norms for Reuse of Residual Clinical Biospecimens and Health Data.

Elizabeth E Umberfield, Sharon L R Kardia, Yun Jiang, Andrea K Thomer, Marcelline R Harris,

Nurse scientists are increasingly interested in conducting secondary research using real world collections of biospecimens and health data. The purposes of this scoping review are to (a) identify federal regulations and norms that bear authority or give guidance over reuse of residual clinical biospecimens and health data, (b) summarize domain ... Read more >>

West J Nurs Res (Western journal of nursing research)
[2021, :1939459211029296]

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Intensive vegetable production results in high nitrate accumulation in deep soil profiles in China.

Xinlu Bai, Yun Jiang, Hongzhi Miao, Shaoqi Xue, Zhujun Chen, Jianbin Zhou,

A comprehensive understanding of the patterns and controlling factors of nitrate accumulation in intensive vegetable production is essential to solve this problem. For the first time, the national patterns and controlling factors of nitrate accumulation in soil of vegetable systems in China were analysed by compiling 1262 observations from 117 ... Read more >>

Environ Pollut (Environmental pollution (Barking, Essex : 1987))
[2021, 287:117598]

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Dynamics of Bacterial and Fungal Communities and Metabolites During Aerobic Exposure in Whole-Plant Corn Silages With Two Different Moisture Levels.

Chunsheng Bai, Chao Wang, Lin Sun, Haiwen Xu, Yun Jiang, Na Na, Guomei Yin, Sibo Liu, Yanlin Xue,

The study was aimed to investigate the effect of moisture content on microbial communities, metabolites, fermentation quality, and aerobic stability during aerobic exposure in whole-plant corn silages preserved long time to improve the quality and aerobic stability of the silage during feed-out. Corn plants with two different moisture levels (high-moisture ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2021, 12:663895]

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Low Carbohydrate Diet Score and the Risk of Metabolic Syndrome in Chinese Adults

Baofu Guo, Xiaocheng Li, Di Jin, Hui Zuo, Fangyan Zhu, Yanli Wang, Yun Jiang, Baichun Zhu, Liankai Ma, Guoxiang Xie, Nan Zhou,

Previous studies on estimated associations between low carbohydrate diet (LCD) score and metabolic syndrome (MetS) are inconsistent. We aim to assess the association between LCD score and MetS in a Chinese population. A multi-stage random sampling method was applied and a total of 1993 participants aged more than 18 years ... Read more >>

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Feasibility of MR fingerprinting using a high-performance 0.55 T MRI system.

Adrienne E Campbell-Washburn, Yun Jiang, Gregor Körzdörfer, Mathias Nittka, Mark A Griswold,

<h4>Background</h4>MR fingerprinting (MRF) is a versatile method for rapid multi-parametric quantification. The application of MRF for lower MRI field could enable multi-contrast imaging and improve exam efficiency on these systems. The purpose of this work is to demonstrate the feasibility of 3D whole-brain T1 and T2 mapping using MR fingerprinting ... Read more >>

Magn Reson Imaging (Magnetic resonance imaging)
[2021, 81:88-93]

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Effect of Lactobacillus hilgardii, Lactobacillus buchneri, or their combination on the fermentation and nutritive value of sorghum silage and corn silage.

Kathy G Arriola, Diwakar Vyas, Donghyeon Kim, Mariele C N Agarussi, Vanessa P Silva, Milton Flores, Yun Jiang, Xue Yanlin, Andres A Pech-Cervantes, Luiz F Ferraretto, Adegbola T Adesogan,

The objective of this study was to determine the effect of inoculation with Lactobacillus hilgardii with or without Lactobacillus buchneri on the fermentation, chemical composition, and aerobic stability of sorghum and corn silage after 2 ensiling durations. Sorghum forage was harvested at 27% dry matter (DM; experiment 1), and different ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, :]

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Crosstalk between reactive oxygen species and Dynamin-related protein 1 in periodontitis.

Lixi Shi, Yinghui Ji, Shufan Zhao, Houxuan Li, Yun Jiang, Jiajie Mao, Yang Chen, Xiaorong Zhang, Yixin Mao, Xiaoyu Sun, Panpan Wang, Jianfeng Ma, Shengbin Huang,

Excessive generation of reactive oxygen species (ROS) have great impacts on the development of periodontitis. Dynamin-related protein 1 (Drp1) mediated mitochondrial fission is the main reason and the result of excessive ROS generation. However, whether Drp1 and crosstalk between ROS and Drp1 contribute to the process of periodontitis remains elusive. ... Read more >>

Free Radic Biol Med (Free radical biology & medicine)
[2021, 172:19-32]

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Attention-Guided Network with Densely Connected Convolution for Skin Lesion Segmentation.

Shengxin Tao, Yun Jiang, Simin Cao, Chao Wu, Zeqi Ma,

The automatic segmentation of skin lesions is considered to be a key step in the diagnosis and treatment of skin lesions, which is essential to improve the survival rate of patients. However, due to the low contrast, the texture and boundary are difficult to distinguish, which makes the accurate segmentation ... Read more >>

Sensors (Basel) (Sensors (Basel, Switzerland))
[2021, 21(10):]

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Efficient endo-β-1,3-glucanase expression in Pichia pastoris for co-culture with Agrobacterium sp. for direct curdlan oligosaccharide production.

Minjie Gao, Guoshuai Yang, Feifei Li, Zichao Wang, Xiuyu Hu, Yun Jiang, Jiajun Yan, Zhitao Li, Xiaobei Zhan,

The production of curdlan oligosaccharides, a multifunctional and valuable carbohydrate, by hydrolyzing polysaccharides is of great interest. The endo-β-1,3-glucanase derived from Trichoderma harzianum was expressed in Pichia pastoris with three commonly used promoters (AOX1, GAP and FLD1). The purified recombinant endo-β-1,3-glucanase expressed by Pichia pastoris with GAP promoter displayed high ... Read more >>

Int J Biol Macromol (International journal of biological macromolecules)
[2021, 182:1611-1617]

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Nanoscopic wear behavior of dentinogenesis imperfecta type II tooth dentin.

Jiajie Mao, Lin Wang, Yun Jiang, Haoran Cheng, Ning Li, Shi Shi, Fan Fan, Jianfeng Ma, Shengbin Huang,

<h4>Objectives</h4>The aim of this study was to investigate the wear behavior of Dentinogenesis imperfecta type II (DGI-II) dentin and elucidate the correlation between its tribological properties and components.<h4>Methods</h4>The mid-coronal dentin of normal and DGI-II teeth were divided into two groups: perpendicular and parallel to the dentin tubules. The microstructure of ... Read more >>

J Mech Behav Biomed Mater (Journal of the mechanical behavior of biomedical materials)
[2021, 120:104585]

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One-step production of functional branched oligoglucosides with coupled fermentation of Pichia pastoris GS115 and Sclerotium rolfsii WSH-G01.

Minjie Gao, Ying Xu, Guoshuai Yang, Shuxia Jin, Xiuyu Hu, Yun Jiang, Li Zhu, Zhitao Li, Xiaobei Zhan,

Endo-β-1,3-glucanase with high specific activity is a prerequisite for enzymatic preparation of valuable β-oligoglucosides. Heterologous expression in Pichia pastoris GS115 with error-prone PCR technology was implemented, and the mutant strain 7 N12 was obtained. The mutant endo-β-1,3-glucanase showed efficient specific activities for degrading curdlan (366 U mg<sup>-1</sup>) and scleroglucan (274.5 U mg<sup>-1</sup>). Thereafter, one-step production ... Read more >>

Bioresour Technol (Bioresource technology)
[2021, 335:125286]

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In vitro digestion and fecal fermentation of highly resistant starch rice and its effect on the gut microbiota.

Zhi-Tao Li, Guo-Ao Hu, Li Zhu, Zhi-Chao Zhao, Yun Jiang, Min-Jie Gao, Xiao-Bei Zhan,

Highly resistant starch rice (HRSR) is of particular interest in terms of its capacity to deliver short-chain fatty acids (SCFAs) to the colon in the prevention of diabetes mellitus and obesity. In this study, HRSR was processed into cooked rice, rice milk, rice cake, and rice popcorn, and the in ... Read more >>

Food Chem (Food chemistry)
[2021, 361:130095]

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Lessons Learned for Identifying and Annotating Permissions in Clinical Consent Forms.

Elizabeth E Umberfield, Yun Jiang, Susan H Fenton, Cooper Stansbury, Kathleen Ford, Kaycee Crist, Sharon L R Kardia, Andrea K Thomer, Marcelline R Harris,

<h4>Background</h4>The lack of machine-interpretable representations of consent permissions precludes development of tools that act upon permissions across information ecosystems, at scale.<h4>Objectives</h4>To report the process, results, and lessons learned while annotating permissions in clinical consent forms.<h4>Methods</h4>We conducted a retrospective analysis of clinical consent forms. We developed an annotation scheme following the ... Read more >>

Appl Clin Inform (Applied clinical informatics)
[2021, 12(3):429-435]

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Process intensification to produce a difficult-to-express therapeutic enzyme by high cell density perfusion or enhanced fed-batch.

Sigrid Särnlund, Yun Jiang, Veronique Chotteau,

Intensified bioprocesses have caught industrial interest in the field of biomanufacturing in recent years. Thanks to new technology, intensified processes can support high cell densities, higher productivities and longer process times, which together can offer lower cost of goods. In this study two different intensified process modes, high cell density ... Read more >>

Biotechnol Bioeng (Biotechnology and bioengineering)
[2021, :]

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Penitol A and Penicitols E-I: Citrinin Derivatives from Penicillium citrinum and the Structure Revision of Previously Proposed Analogues.

Meimei Cheng, Pinglin Li, Yun Jiang, Xuli Tang, Wenjie Zhang, Qi Wang, Guoqiang Li,

Penitol A (<b>1</b>), a new citrinin derivative with a rare tricyclic spiro skeleton, was isolated from a coral-derived strain of the fungus <i>Penicillium citrinum</i>. In addition, penicitols E-I (<b>2</b>-<b>6</b>), five new citrinin analogues, were coisolated. Their structures were determined by an analysis of 1D/2D NMR and HRESIMS data, statistical DP4+ ... Read more >>

J Nat Prod (Journal of natural products)
[2021, 84(4):1345-1352]

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Meta-analysis of effects of inoculation with Lactobacillus buchneri, with or without other bacteria, on silage fermentation, aerobic stability, and performance of dairy cows.

Kathy G Arriola, André S Oliveira, Yun Jiang, Donghyeon Kim, Henrique M Silva, Sam Churl Kim, Felipe X Amaro, Ibukun M Ogunade, Halima Sultana, Andres A Pech Cervantes, Luiz F Ferraretto, Diwakar Vyas, Adegbola T Adesogan,

A meta-analysis of 158 peer-reviewed articles was conducted to examine effects of inoculation with Lactobacillus buchneri (LB)-based inoculants (LBB) that did or did not include homolactic or obligate heterolactic bacteria on silage fermentation and aerobic stability. A complementary meta-analysis of 12 articles examined LBB inoculation effects on dairy cow performance. ... Read more >>

J Dairy Sci (Journal of dairy science)
[2021, 104(7):7653-7670]

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Effect of lactic acid stress on biofilm formation of Escherichia coli O26 at different temperatures

Xiaoyu Mi, Jie Hu, Su Zhang, Siqi Wang, Wangchen Zhao, Longfeng Wang, Yun Jiang,

Similar to Escherichia coli O157, non‐O157 also inherits certain acid resistance, and its stress response can be induced under acidic conditions, which may be affected by temperature. In this study, O26, the main serotype of non‐O157 E. coli, was investigated in order to evaluate the effect of lactic acid stress ... Read more >>

(Journal of food safety.)
[2021, 41(2):Not Available]

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Succession of Bacterial Community During the Initial Aerobic, Intense Fermentation, and Stable Phases of Whole-Plant Corn Silages Treated With Lactic Acid Bacteria Suspensions Prepared From Other Silages.

Lin Sun, Chunsheng Bai, Haiwen Xu, Na Na, Yun Jiang, Guomei Yin, Sibo Liu, Yanlin Xue,

The present study was aimed at investigating the bacterial community in lactic acid bacteria (LAB) suspensions prepared from whole-plant corn silage (LAB suspension-CS) and <i>Elymus sibiricus</i> silage (LAB suspension-ES) and the bacterial community succession of whole-plant corn silages inoculated with LAB suspension-CS or LAB suspension-ES during initial aerobic phase, intense ... Read more >>

Front Microbiol (Frontiers in microbiology)
[2021, 12:655095]

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Acceptance and Use of Home-Based Electronic Symptom Self-Reporting Systems in Patients With Cancer: Systematic Review.

Youmin Cho, Huiting Zhang, Marcelline Ruth Harris, Yang Gong, Ellen Lavoie Smith, Yun Jiang,

<h4>Background</h4>Electronic symptom self-reporting systems (e-SRS) have been shown to improve symptoms and survival in patients with cancer. However, patient engagement in using e-SRS for voluntary symptom self-reporting is less optimal. Multiple factors can potentially affect patients' acceptance and engagement in using home-based e-SRS. However, such factors have not been fully ... Read more >>

J Med Internet Res (Journal of medical Internet research)
[2021, 23(3):e24638]

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Evaluation of the pharmacokinetic effects of itraconazole on alflutinib (AST2818): an open-label, single-center, single-sequence, two-period randomized study in healthy volunteers.

Jianfu Heng, Qi Tang, Xue Chen, Jingjing Bao, Jun Deng, Yong Chen, Jiao Zhao, Songlin Zhu, Xiaobao Liu, Feng Yang, Yun Jiang, Nong Yang, Kunyan Li,

Alflutinib (AST2818) is a newly developed third-generation EGFR tyrosine kinase inhibitor for the treatment of lung cancer patients with T790M-resistant mutations. It is metabolized mainly by the CYP3A4 enzyme. At the same time, it has the potential to induce CYP3A4. In this study, we aimed to estimate the effect of ... Read more >>

Eur J Pharm Sci (European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences)
[2021, 162:105815]

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Biotransformation of alkylamides and alkaloids by lactic acid bacteria strains isolated from Zanthoxylum bungeanum meal.

Chenman Li, Qing Kong, Haijin Mou, Yun Jiang, Yongli Du, Fang Zhang,

Zanthoxylum bungeanum meal (ZBM) is the by-product of Z. bungeanum seeds after pressing. It is restricted as a feed additive because it contains stimulating and potentially harmful substances, which are alkylamides and alkaloids. This study described the use of Lactobacillus paracasei and L. acidipiscis isolated from ZBM in solid-state fermentation ... Read more >>

Bioresour Technol (Bioresource technology)
[2021, 330:124944]

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Neighborhood effects and environmental variables drive sapling growth in a young subtropical tree plantation

Zhiqiang Shen, Yuanzhi Li, Zhiyi Chen, Bingwei Zhang, Yonglin Zhong, Nianxun Xi, Xianhui Zhu, Wei Lin, Qing He, Wenqi Luo, Songling Liu, Wei Wei, Hanlun Liu, Yun Jiang, Weitao Wang, Dongxia Chen, Junli Xiao, Hui Tang, Buhang Li, Chengjin Chu, Youshi Wang,

We established a forest biodiversity and ecosystem functioning experiment in southern China by planting 20,480 saplings of eight subtropical tree species in 320 plots in monocultures and mixtures of two, four and eight species to explore the biodiversity-ecosystem functioning (BEF) relationships and the underlying coexistence determinants. In this study, we ... Read more >>

For Ecol Manage (Forest ecology and management.)
[2021, 483:Not Available]

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Study of growth, metabolism, and morphology of Akkermansia muciniphila with an in vitro advanced bionic intestinal reactor.

Zhitao Li, Guoao Hu, Li Zhu, Zhenglong Sun, Yun Jiang, Min-Jie Gao, Xiaobei Zhan,

<h4>Background</h4>As a kind of potential probiotic, Akkermansia muciniphila abundance in human body is directly causally related to obesity, diabetes, inflammation and abnormal metabolism. In this study, A. muciniphila dynamic cultures using five different media were implemented in an in vitro bionic intestinal reactor for the first time instead of the ... Read more >>

BMC Microbiol (BMC microbiology)
[2021, 21(1):61]

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Dietary taurine supplementation ameliorates muscle loss in chronic heat stressed broilers via suppressing the perk signaling and reversing endoplasmic reticulum‐stress‐induced apoptosis

Bingbing Ma, Lin Zhang, Jiaolong Li, Tong Xing, Yun Jiang, Feng Gao,

BACKGROUND: Heat stress seriously affects animal health and induces enormous financial losses in poultry production. Exploring the appropriate means for ameliorating unfavorable effects caused by heat stress is essential. We investigated whether taurine supplementation could attenuate breast muscle loss in chronic heat‐stressed broilers, as well as its mechanism. We designed ... Read more >>

J Sci Food Agric (Journal of the science of food and agriculture)
[2021, 101(5):2125-2134]

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