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Author Yuho Horikoshi

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A 15-Month-old Boy With Kawasaki Disease-like Symptoms.

Hiroshi Hayashi, Kazuhiro Uda, Keiji Akamine, Nanako Kawata, Shogo Akahoshi, Masaki Shimizu, Yuho Horikoshi, Hiroshi Hataya,

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2021, 40(2):173-174]

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Impact of methicillin-resistant Staphylococcus aureus colonization in a neonatal intensive care unit after discharge.

Jumpei Kuroda, Kaoru Okazaki, Takemi Murai, Yuta Aizawa, Yuho Horikoshi,

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2020, :]

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Nationwide surveillance of bacterial pathogens isolated from children conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2017: General overview of pathogenic antimicrobial susceptibility.

Naruhiko Ishiwada, Kazuo Fujimaki, Tetsuya Matsumoto, Hiroshi Kiyota, Kazuhiro Tateda, Junko Sato, Hideaki Hanaki, Reiko Takayanagi, Yoshio Yamaguchi, Tadashi Hoshino, Haruo Kuroki, Satoshi Iwata, Takeshi Tajima, Yuho Horikoshi, Hiroyuki Shiro, Masahiro Bamba, Naohisa Kawamura, Kazunobu Ouchi, Keita Matsubara, Takafumi Okada, Kenji Furuno, Naoki Tsumura,

A nationwide surveillance of the antimicrobial susceptibility of pediatric patients to bacterial pathogens was conducted by Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in Japan in 2017. The isolates were collected from 18 medical facilities between March 2017 and May ... Read more >>

J Infect Chemother (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2020, :]

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Kawasaki disease following coronavirus disease 2019 with prolonged fecal viral shedding.

Kazuhiro Uda, Keiko Okita, Keiko Soneda, Kimihiro Taniguchi, Yuho Horikoshi,

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2020, :]

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School-based approach for parasitic diseases control in Japan and Africa.

Yuho Horikoshi, Usman Muhammad Ibrahim, Shaun K Morris,

Japan has achieved significant improvements in control and prevention of parasitic infections through school-based approach since 1930s. The use of chemical fertilizer in agriculture, safe water and food, and improved sanitation and hygiene also contributed to the near eradication of endemic parasites. However, parasite infections continued to affect children mostly ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2020, :]

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Impacts of Primary Care Physician System on Healthcare Utilization and Antibiotic Prescription: Difference-in-Differences and Causal Mediation Analyses.

Yusuke Okubo, Nobuaki Michihata, Kazuhiro Uda, Noriko Kinoshita, Yuho Horikoshi, Isao Miyairi,

BACKGROUND:The overutilization of healthcare and overuse/misuse of antibiotics in Japan are responsible for the increase in healthcare expenditure and the development of antimicrobial resistance. The Japanese government started paying incentives to medical facilities for primary care physician registrations, but the impact of this new policy is still unclear. METHODS:We conducted ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2020, 39(10):937-942]

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National trends in appropriate antibiotics use among pediatric inpatients with uncomplicated lower respiratory tract infections in Japan.

Yusuke Okubo, Kazuhiro Uda, Noriko Kinoshita, Yuho Horikoshi, Isao Miyairi, Nobuaki Michihata, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga,

BACKGROUND:Japan was ranked as the worst country of 36 high-income countries in terms of oral antibiotic consumptions for children. Knowing the patterns and variations of antibiotic use for pediatric inpatients with uncomplicated respiratory infections is an important step to promote judicious antibiotic use. METHODS:Discharge records were extracted for children aged ... Read more >>

J Infect Chemother (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2020, 26(11):1122-1128]

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First case of Legionella pneumonia in a female patient with anorexia nervosa.

Manami Sammori, Hanako Funakoshi, Yoshimitsu Fukai, Naoki Shimizu, Yuho Horikoshi,

J Paediatr Child Health (Journal of paediatrics and child health)
[2020, :]

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CTX-M group gene distribution of extended spectrum beta-lactamase-producing Enterobacteriaceae at a Japanese Children's hospital.

Takayuki Yamanaka, Hanako Funakoshi, Kazue Kinoshita, Chinami Iwashita, Yuho Horikoshi,

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae have spread globally as one of the most common multidrug resistant organisms. Although a wide variety of ESBL genes were known in each geographical region, few reports existed on the distribution of ESBL genes in Japanese children. To clarify the distribution of ESBL genes, we investigated ... Read more >>

J Infect Chemother (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2020, 26(9):1005-1007]

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Prospective monitoring of carbapenem use and pseudomonal resistance across pediatric institutions.

Isao Miyairi, Kensuke Shoji, Noriko Kinoshita, Junpei Saitoh, Yoshie Sugahara, Yasushi Watanabe, Makoto Komura, Masashi Kasai, Yuho Horikoshi, Masayoshi Shinjoh, Takashi Igarashi, ,

OBJECTIVE:To determine whether carbapenem consumption and Pseudomonas aeruginosa resistance rates can be used as benchmarks to compare and improve antimicrobial stewardship programs across multiple pediatric hospitals. DESIGN:A prospective study. SETTING AND PARTICIPANTS:Healthcare institutions in Japan with >100 pediatric beds. METHODS:An annual survey of the total days of therapy (DOT) per ... Read more >>

Infect Control Hosp Epidemiol (Infection control and hospital epidemiology)
[2020, 41(9):1042-1047]

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Pediatric acute dacryocystitis due to Eikenella corrodens: A case report.

Miki Tanaka, Kotaro Araki, Hiroshi Higuchi, Kahoru Fukuoka-Araki, Yuho Horikoshi, Hiroshi Hataya,

Eikenella corrodens is a facultatively anaerobic gram-negative rod bacterium in the oropharynx and respiratory tract. It is a member of HACEK (Haemophilus spp., Aggregatibacter spp., Cardiobacterium hominis, E. corrodens, and Kingella kingae) group commonly associated with endocarditis and craniofacial infections. It is usually susceptible to penicillin, second and third-generation cephalosporins, and ... Read more >>

J Infect Chemother (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2020, 26(5):510-512]

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Diagnostic errors in pediatric bacterial osteomyelitis.

Yuki Otani, Yuta Aizawa, Hiroshi Hataya, Yuho Horikoshi,

<h4>Background</h4>Clinical evidence for improving diagnostic accuracy in pediatric medicine is still scarce. Septic osteomyelitis is sometimes challenging for physicians to diagnose. The aim of this study was to improve patient care through identifying the incidence and reasons for errors in the diagnosis of bacterial osteomyelitis in pediatric patients.<h4>Methods</h4>We retrospectively identified ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2019, 61(10):988-993]

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Incidence and aetiology of serious viral infections in young febrile infants.

Itaru Hayakawa, Osamu Nomura, Kazuhiro Uda, Yu Funakoshi, Hiroshi Sakakibara, Yuho Horikoshi,

AIM:While the incidence and aetiology of serious bacterial infections among febrile infants younger than 90 days old are well studied, those concerning viral infection are not. There are severe life-threatening viral infections requiring immediate intense therapy. The objective of the study is to describe the incidence and aetiology of serious viral ... Read more >>

J Paediatr Child Health (Journal of paediatrics and child health)
[2020, 56(4):586-589]

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1148. Antimicrobial Stewardship Program at a Long-term Care Hospital for Severely Handicapped Children and Adults.

Sho Ishii, Kazuhiro Uda, Yasuko Kudo, Koji Fukano, Masako Igari, Tetsuji Kaneko, Kazuhiko Morikawa, Wakana Furushima, Kahoru Fukuoka, Ayaka Koide, Yuho Horikoshi,

AbstractBackgroundAlthough antimicrobial stewardship program (ASP) is also recommended for a long-term care facility (LTCF), research on ASP in LTCFs is still limited. Our study was conducted at an LTCF offering chronic medical care for pediatric and adult patients with extensive medical needs since childhood. Our aim of this study was ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2019, 6(Suppl 2):S409-S410]

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Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015.

Yu Funakoshi, Kenta Ito, Saeko Morino, Kazue Kinoshita, Yoshihiko Morikawa, Tatsuo Kono, Yen Hai Doan, Hiroyuki Shimizu, Nozomu Hanaoka, Masami Konagaya, Tsuguto Fujimoto, Ai Suzuki, Takashi Chiba, Tetsuya Akiba, Yasuhiro Tomaru, Ken Watanabe, Norio Shimizu, Yuho Horikoshi,

<h4>Background</h4>Outbreaks of enterovirus D68 (EV-D68) respiratory infections in children were reported globally in 2014. In Japan, there was an EV-D68 outbreak in the autumn of 2015 (September-October). The aim of this study was to compare EV-D68-specific polymerase chain reaction (PCR)-positive and EV-D68-specific PCR-negative patients.<h4>Methods</h4>Pediatric patients admitted for any respiratory symptoms ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2019, 61(8):768-776]

Cited: 2 times

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Ototoxicity and Nephrotoxicity With Elevated Serum Concentrations Following Vancomycin Overdose: A Retrospective Case Series.

Kazuhiro Uda, Junichi Suwa, Kenta Ito, Hiroshi Hataya, Yuho Horikoshi,

Although a high vancomycin serum concentration is known to be associated with nephrotoxicity, its association with ototoxicity is not well known. The purpose of our study was to examine the latter association in pediatric patients, especially in cases of accidental overdose. Pediatric patients who received vancomycin at our facility between ... Read more >>

J Pediatr Pharmacol Ther (The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG)
[2019, 24(5):450-455]

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Trends in varicella and mumps vaccination rates in children under 3 years of age in a tertiary children's hospital in Japan.

Yoshihiko Morikawa, Saeko Morino, Kenta Ito, Mihoko Furuichi, Shigeko Miyokawa, Takayo Shoji, Yuho Horikoshi,

<h4>Background</h4>In Japan, the voluntary vaccination rate is not known accurately. Although two doses of the measles and rubella vaccines have been part of the universal vaccine program since 2006, the varicella vaccine was added in October 2014 while the mumps vaccine still remains voluntary. The aim of this study was ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2019, 61(9):882-888]

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Multidrug-resistant Gram-negative Bacterial Bloodstream Infections in Children's Hospitals in Japan, 2010-2017.

Yuta Aizawa, Takayo Shoji, Kenta Ito, Masashi Kasai, Hiroki Sakurai, Etsushi Toyofuku, Kisei Minami, Tadashi Hoshino, Yuho Horikoshi,

<h4>Background</h4>The risk factors of multidrug-resistant (MDR) Gram-negative bacilli (GNB) bloodstream infection (BSI) are not yet known in children. Our aim was to evaluate risk factors and outcomes associated with MDR GNB BSI in children.<h4>Methods</h4>Patients with GNB BSI were enrolled between April 2010 and March 2017 at 8 children's hospitals in ... Read more >>

Pediatr Infect Dis J (The Pediatric infectious disease journal)
[2019, 38(7):653-659]

Cited: 1 time

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Nationwide survey of indications for oral antimicrobial prescription for pediatric patients from 2013 to 2016 in Japan.

Kazuhiro Uda, Yusuke Okubo, Noriko Kinoshita, Naho Morisaki, Masahi Kasai, Yuho Horikoshi, Isao Miyairi,

<h4>Background</h4>Antimicrobial resistance is a major public health concern. In 2016, the Japanese government launched a national action plan aimed at achieving a 33% and 50% reduction in the number of total and oral antimicrobial prescriptions (cephalosporins, macrolides, and quinolones) from the 2013 figures by 2020, respectively. The purpose of this ... Read more >>

J Infect Chemother (Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy)
[2019, 25(10):758-763]

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Cefmetazole for extended-spectrum β-lactamase-producing Enterobacteriaceae in pediatric pyelonephritis.

Kotaro Araki, Kahoru Fukuoka, Hiroshi Higuchi, Yuta Aizawa, Yuho Horikoshi,

BACKGROUND:Pyelonephritis caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is an urgent problem in pediatrics. Although carbapenem is the standard therapy for infections caused by ESBL-producing Enterobacteriaceae, some cephamycins, including cefmetazole, are stable against hydrolysis by ESBL. There are few reports, however, on the use of cefmetazole in children. The aim of ... Read more >>

Pediatr Int (Pediatrics international : official journal of the Japan Pediatric Society)
[2019, 61(6):572-577]

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White chalky dermatitis in a very preterm neonate with fungal skin infection.

Yutaro Tomobe, Ryu Yoneda, Yuho Horikoshi, Kaoru Okazaki,

Arch Dis Child Fetal Neonatal Ed (Archives of disease in childhood. Fetal and neonatal edition)
[2019, 104(4):F383]

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Comparison of USA300 with non-USA300 methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit.

Takemi Murai, Kaoru Okazaki, Kazue Kinoshita, Yuki Uehara, Hui Zuo, Yujie Lu, Yuki Ono, Takashi Sasaki, Keiichi Hiramatsu, Yuho Horikoshi,

<h4>Objectives</h4>Reports of USA300 methicillin-resistant Staphylococcus aureus (MRSA) strain were still scarce in neonatal intensive care units (NICUs) and the relationship of USA300 MRSA to clinical infections is still controversial. The primary outcome was the incidence of MRSA infections caused by the USA300 and non-USA300 strains at a NICU in Japan.<h4>Methods</h4>This ... Read more >>

Int J Infect Dis (International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases)
[2019, 79:134-138]

Cited: 2 times

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1917. Diagnostic Errors in Bacterial Osteomyelitis in Children.

Yuki Otani, Yuta Aizawa, Hiroshi Hataya, Yuho Horikoshi,

AbstractBackgroundDelayed or erroneous diagnoses of bacterial infections may cause adverse outcomes in patients. Bacterial osteomyelitis has a low incidence, is only infrequently encountered by primary care pediatricians, and has obscure symptoms in children that make an early and accurate diagnosis challenging. The aim of this study was to determine the ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2018, 5(Suppl 1):S552-S552]

Cited: 0 times

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Caterpillar Sign in an Infant with Hypertrophic Pyloric Stenosis.

Reiko Kawai, Kazuhiro Uda, Yuho Horikoshi, Hiroshi Hataya,

J Pediatr (The Journal of pediatrics)
[2019, 208:292]

Cited: 0 times

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2334. Risk Factors of Multidrug-Resistant Gram-Negative Bacterial Bloodstream Infections in Children’s Hospitals in Japan.

Yuta Aizawa, Takayo Shoji, Kenta Ito, Masashi Kasai, Hiroki Sakurai, Etsushi Toyofuku, Kisei Minami, Tadashi Hoshino, Yuho Horikoshi,

AbstractBackgroundAlthough multidrug-resistant (MDR) Gram-negative bacilli (GNB) are a serious and growing concern worldwide, the epidemiological data on children are still limited. Our aim was to evaluate the risk factors for MDR GNB bloodstream infections (BSI) in children.MethodsPatients with GNB BSI were enrolled between April 2010 and March 2017 at eight ... Read more >>

Open Forum Infect Dis (Open forum infectious diseases)
[2018, 5(Suppl 1):S693-S694]

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